Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold (English)
- New search for: Jia, Jian-Min
- New search for: Jia, Jian-Min
- New search for: Liu, Fang
- New search for: Xu, Xiao-Li
- New search for: Guo, Xiao-Ke
- New search for: Jiang, Fen
- New search for: Cherfaoui, Bahidja
- New search for: Sun, Hao-Peng
- New search for: You, Qi-Dong
In:
Bioorganic & medicinal chemistry letters
;
24
, 6
; 1557-1561
;
2014
-
ISSN:
- Article (Journal) / Print
-
Title:Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffold
-
Contributors:Jia, Jian-Min ( author ) / Liu, Fang / Xu, Xiao-Li / Guo, Xiao-Ke / Jiang, Fen / Cherfaoui, Bahidja / Sun, Hao-Peng / You, Qi-Dong
-
Published in:Bioorganic & medicinal chemistry letters ; 24, 6 ; 1557-1561
-
Publisher:
- New search for: Elsevier
-
Place of publication:Amsterdam [u.a.]
-
Publication date:2014
-
ISSN:
-
ZDBID:
-
Type of media:Article (Journal)
-
Type of material:Print
-
Language:English
- New search for: 35.70 / 44.33 / 44.42
- Further information on Basic classification
-
Keywords:
-
Classification:
-
Source:
Table of contents – Volume 24, Issue 6
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1443
-
Graphical contents list| 2014
- 1452
-
Novel dimeric Smac analogs as prospective anticancer agentsMicewicz, Ewa D. / Luong, Hai T. / Jung, Chun-Ling / Waring, Alan J. / McBride, William H. / Ruchala, Piotr et al. | 2014
- 1458
-
cis-1-Oxo-heterocyclyl-4-amido cyclohexane derivatives as NPY5 receptor antagonistsBurns, James Ford / Chen, Bin / Chen, Chien-An / Doller, Dario / Edelmenky, Eman / Jiang, Yu / Peterson, John M. / Sabio, Michael / Weiss, Jessie / White, Andrew D. et al. | 2014
- 1462
-
Synthesis and antiproliferative evaluation of 13-aryl-13H-benzo[g]benzothiazolo [2,3-b]quinazoline-5,14-dionesWu, Liqiang / Zhang, Chong / Li, Weilin et al. | 2014
- 1466
-
The discovery of reverse tricyclic pyridone JAK2 inhibitors. Part 2: Lead optimizationSiu, Tony / Kumarasinghe, Sathyajith E. / Altman, Michael D. / Katcher, Matthew / Northrup, Alan / White, Catherine / Rosenstein, Craig / Mathur, Anjili / Xu, Lin / Chan, Grace et al. | 2014
- 1472
-
Evaluation of nicotine and cotinine analogs as potential neuroprotective agents for Alzheimer’s diseaseGao, Jie / Adam, Bao-Ling / Terry, Alvin V. Jr. et al. | 2014
- 1479
-
The synthesis of 4,7-disubstituted-2H-benzo[b][1,4]-oxazin-3(4H)-ones using Smiles rearrangement and their in vitro evaluation as platelet aggregation inhibitorsXia, Shuai / Liu, Ji-Qiang / Wang, Xiu-Hua / Tian, Ye / Wang, Yu / Wang, Jing-Huan / Fang, Liang / Zuo, Hua et al. | 2014
- 1484
-
Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 proteinPetros, Andrew M. / Swann, Steven L. / Song, Danying / Swinger, Kerren / Park, Chang / Zhang, Haichao / Wendt, Michael D. / Kunzer, Aaron R. / Souers, Andrew J. / Sun, Chaohong et al. | 2014
- 1489
-
5-Hydroxy-2-(2-phenylethyl)chromone (5-HPEC): A novel non-nitrogenous ligand for 5-HT2B receptorWilliams, Dwight A. / Zaidi, Saheem A. / Zhang, Yan et al. | 2014
- 1493
-
4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing phenothiazines as antitubercular agentsSiddiqui, Arif B. / Trivedi, Amit R. / Kataria, Vipul B. / Shah, Viresh H. et al. | 2014
- 1496
-
Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agentsAng, Wei / Ye, Weiwei / Sang, Zitai / Liu, Yuanyuan / Yang, Tao / Deng, Yong / Luo, Youfu / Wei, Yuquan et al. | 2014
- 1502
-
Activity of caffeic acid derivatives against Candida albicans biofilmDe Vita, Daniela / Friggeri, Laura / D’Auria, Felicia Diodata / Pandolfi, Fabiana / Piccoli, Francesco / Panella, Simona / Palamara, Anna Teresa / Simonetti, Giovanna / Scipione, Luigi / Di Santo, Roberto et al. | 2014
- 1506
-
Preparation and optimization of new 4-(2-(indolin-1-yl)-2-oxoethyl)-2-morpholinothiazole-5-carboxylic acid and amide derivatives as potent and selective PI3Kβ inhibitorsCertal, Victor / Halley, Frank / Virone-Oddos, Angela / Filoche-Rommé, Bruno / Carry, Jean-Christophe / Gruss-Leleu, Florence / Bertin, Luc / Guizani, Houlfa / Pilorge, Fabienne / Richepin, Patrick et al. | 2014
- 1506
-
Preparation and optimization of new 4-(2-(indolin-1-yl)-2-oxoethyl)-2-morpholinothiazole-5-carboxylic acid and amide derivatives as potent and selective PI3K@b inhibitorsCertal, V. / Halley, F. / Virone-Oddos, A. / Filoche-Romme, B. / Carry, J. C. / Gruss-Leleu, F. / Bertin, L. / Guizani, H. / Pilorge, F. / Richepin, P. et al. | 2014
- 1511
-
Synthesis and antitumor activities of novel dipeptide derivatives derived from dehydroabietic acidHuang, Xiao-Chao / Wang, Meng / Wang, Heng-Shan / Chen, Zhen-Feng / Zhang, Ye / Pan, Ying-Ming et al. | 2014
- 1519
-
Synthesis of ethynylbenzene-substituted glycol as a versatile probe for labeling oligonucleotidesRen, Qin / Tsunaba, Kana / Kitamura, Yoshiaki / Nakashima, Remi / Shibada, Aya / Ikeda, Masato / Kitade, Yukio et al. | 2014
- 1523
-
Discovery of dual ZAP70 and Syk kinases inhibitors by docking into a rare C-helix-out conformation of SykZhao, Hongtao / Caflisch, Amedeo et al. | 2014
- 1528
-
Synthesis of novel l-rhamnose derived acyclic C-nucleosides with substituted 1,2,3-triazole core as potent sodium-glucose co-transporter (SGLT) inhibitorsPutapatri, Siddamal Reddy / Kanwal, Abhinav / Banerjee, Sanjay K. / Kantevari, Srinivas et al. | 2014
- 1532
-
Discovery of 1,3,4-oxidiazole scaffold compounds as inhibitors of superoxide dismutase expressionLukas, Thomas J. / Schiltz, Gary E. / Arrat, Hasan / Scheidt, Karl / Siddique, Teepu et al. | 2014
- 1538
-
Development of tag-free photoprobes for studies aimed at identifying the target of novel Group A Streptococcus antivirulence agentsYestrepsky, Bryan D. / Kretz, Colin A. / Xu, Yuanxi / Holmes, Autumn / Sun, Hongmin / Ginsburg, David / Larsen, Scott D. et al. | 2014
- 1545
-
Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esteraseMuscia, Gisela C. / Hautmann, Stephanie / Buldain, Graciela Y. / Asís, Silvia E. / Gütschow, Michael et al. | 2014
- 1550
-
Preparation and evaluation of novel pyrazolo[1,5-a]pyrimidine acetamides, closely related to DPA-714, as potent ligands for imaging the TSPO 18kDa with PETMédran-Navarrete, Vincent / Damont, Annelaure / Peyronneau, Marie-Anne / Kuhnast, Bertrand / Bernards, Nicholas / Pottier, Géraldine / Marguet, Frank / Puech, Frédéric / Boisgard, Raphaël / Dollé, Frédéric et al. | 2014
- 1557
-
Synthesis and evaluation of a novel class Hsp90 inhibitors containing 1-phenylpiperazine scaffoldJia, Jian-Min / Liu, Fang / Xu, Xiao-Li / Guo, Xiao-Ke / Jiang, Fen / Cherfaoui, Bahidja / Sun, Hao-Peng / You, Qi-Dong et al. | 2014
- 1562
-
Sinugyrosanolide A, an unprecedented C-4 norcembranoid, from the Formosan soft coral Sinularia gyrosaCheng, Shi-Yie / Shih, Neng-Lang / Chuang, Cheng-Ta / Chiou, Shu-Fen / Yang, Chia-Ning / Wang, Shang-Kwei / Duh, Chang-Yih et al. | 2014
- 1565
-
Inhibition of cellular proliferation and induction of apoptosis in human lung adenocarcinoma A549 cells by T-type calcium channel antagonistChoi, Doo Li / Jang, Sun Jeong / Cho, Sehyeon / Choi, Hye-Eun / Rim, Hong-Kun / Lee, Kyung-Tae / Lee, Jae Yeol et al. | 2014
- 1571
-
New C4- and C1-derivatives of furo[3,4-c]pyridine-3-ones and related compounds: Evidence for site-specific inhibition of the constitutive proteasome and its immunoisoformHovhannisyan, Anna / Pham, The Hien / Bouvier, Dominique / Piroyan, Alexander / Dufau, Laure / Qin, Lixian / Cheng, Yan / Melikyan, Gagik / Reboud-Ravaux, Michèle / Bouvier-Durand, Michelle et al. | 2014
- 1581
-
Discovery and structure–activity relationships study of novel thieno[2,3-b]pyridine analogues as hepatitis C virus inhibitorsWang, Ning-Yu / Zuo, Wei-Qiong / Xu, Ying / Gao, Chao / Zeng, Xiu-Xiu / Zhang, Li-Dan / You, Xin-Yu / Peng, Cui-Ting / Shen, Yang / Yang, Sheng-Yong et al. | 2014
- 1589
-
Probe development for detection of TERRA 1 intramolecular G-quadruplex formation using a fluorescent adenosine derivativeKim, In Sun / Seo, Young Jun et al. | 2014
- 1592
-
2-Amino-7-substituted benzoxazole analogs as potent RSK2 inhibitorsCostales, Abran / Mathur, Michelle / Ramurthy, Savithri / Lan, Jiong / Subramanian, Sharadha / Jain, Rama / Atallah, Gordana / Setti, Lina / Lindvall, Mika / Appleton, Brent A. et al. | 2014
- 1597
-
Suzuki coupling based synthesis and in vitro cytotoxic evaluation of 7-heteroaryl-substituted camptothecin analogsWang, Lei / Huang, Ying / Zhang, Jie / Tong, Linjiang / Chen, Yi / Lu, Wei / Huang, Qingqing et al. | 2014
- 1600
-
Synthesis and cytotoxic effect of pseudodiosgenyl saponins with thio-ring FZan, Xin / Gao, Jian / Gu, Guofeng / Liu, Shanshan / Sun, Bin / Liu, Lei / Lou, Hong-Xiang et al. | 2014
- 1605
-
Synthesis, antileishmanial activity and docking study of N′-substitutedbenzylidene-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetohydrazidesSangshetti, Jaiprakash N. / Shaikh, Rehan I. / Khan, Firoz A. Kalam / Patil, Rajendra H. / Marathe, Sayali D. / Gade, Wasudev N. / Shinde, Devanand B. et al. | 2014
- 1611
-
Discovery of a cyclopentylamine as an orally active dual NK1 receptor antagonist–serotonin reuptake transporter inhibitorWu, Yong-Jin / He, Huan / Gao, Qi / Wu, Dedong / Bertekap, Robert / Westphal, Ryan S. / Lelas, Snjezana / Newton, Amy / Wallace, Tanya / Taber, Matthew et al. | 2014
- 1615
-
Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like propertiesXiao, Dong / Zhu, Xiaohong / Yu, Younong / Shao, Ning / Wu, Jie / McCormick, Kevin D. / Dhondi, Pawan / Qin, Jun / Mazzola, Robert / Tang, Haiqun et al. | 2014
- 1621
-
Potential α-glucosidase inhibitors from thermal transformation of (+)-catechinKim, Taewan / Choi, Hyo Jin / Eom, Sung-Hwan / Lee, Jaemin / Kim, Tae Hoon et al. | 2014
- 1621
-
Potential @a-glucosidase inhibitors from thermal transformation of (+)-catechinKim, T. / Choi, H. J. / Eom, S. H. / Lee, J. / Kim, T. H. et al. | 2014
- IFC
-
Editorial board| 2014