3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors (English)
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- New search for: Kutz, Craig J.
- New search for: Holshouser, Steven L.
- New search for: Marrow, Ethan A.
- New search for: Woster, Patrick M.
- New search for: Kutz, Craig J.
- New search for: Holshouser, Steven L.
- New search for: Marrow, Ethan A.
- New search for: Woster, Patrick M.
In:
MedChemComm
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5
, 12
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1863-1870
;
2014
- Article (Journal) / Electronic Resource
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Title:3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitors
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Contributors:Kutz, Craig J. ( author ) / Holshouser, Steven L. ( author ) / Marrow, Ethan A. ( author ) / Woster, Patrick M. ( author )
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Published in:MedChemComm ; 5, 12 ; 1863-1870
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Publisher:
- New search for: The Royal Society of Chemistry
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Publication date:2014-11-19
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Size:8 pages
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Source:
Table of contents – Volume 5, Issue 12
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1771
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Front cover| 2014
- 1773
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Contents list| 2014
- 1779
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Structural biology and chemistry of protein arginine methyltransferasesSchapira, Matthieu / Ferreira de Freitas, Renato et al. | 2014
- 1789
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Discovery of an orally active subtype-selective HDAC inhibitor, chidamide, as an epigenetic modulator for cancer treatmentPan, De-Si / Yang, Qian-Jiao / Fu, Xin / Shan, Song / Zhu, Jing-Zhong / Zhang, Kun / Li, Zhi-Bin / Ning, Zhi-Qiang / Lu, Xian-Ping et al. | 2014
- 1797
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Repair of methyl lesions in RNA by oxidative demethylationYe, Fei / Zhang, Liyi / Jin, Lu / Zheng, Mingyue / Jiang, Hualiang / Luo, Cheng et al. | 2014
- 1804
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Can we use the epigenetic bioactivity of caloric restriction and phytochemicals to promote healthy ageing?Christodoulou, Michael. S. / Thomas, Adeline / Poulain, Stéphane / Vidakovic, Melita / Lahtela-Kakkonen, Maija / Matulis, Daumantas / Bertrand, Philippe / Bartova, Eva / Blanquart, Christophe / Mikros, Emmanuel et al. | 2014
- 1821
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Identification of 2,4-diamino-6,7-dimethoxyquinoline derivatives as G9a inhibitorsSrimongkolpithak, Nitipol / Sundriyal, Sandeep / Li, Fengling / Vedadi, Masoud / Fuchter, Matthew J. et al. | 2014
- 1829
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Synthesis of hybrid anticancer agents based on kinase and histone deacetylase inhibitorsPatel, Hiren / Chuckowree, Irina / Coxhead, Peter / Guille, Matthew / Wang, Minghua / Zuckermann, Alexandra / Williams, Robin S. B. / Librizzi, Mariangela / Paranal, Ronald M. / Bradner, James E. et al. | 2014
- 1834
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Evaluation of functional groups as acetyl-lysine mimetics for BET bromodomain inhibitionSharp, Phillip P. / Garnier, Jean-Marc / Huang, David C. S. / Burns, Christopher J. et al. | 2014
- 1843
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Structure-based approaches towards identification of fragments for the low-druggability ATAD2 bromodomainChaikuad, Apirat / Petros, Andrew M. / Fedorov, Oleg / Xu, Jing / Knapp, Stefan et al. | 2014
- 1849
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An azumamide C analogue without the zinc-binding functionalityVilladsen, Jesper S. / Kitir, Betül / Wich, Kathrine / Friis, Tina / Madsen, Andreas S. / Olsen, Christian A. et al. | 2014
- 1856
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Pyrido- and benzisothiazolones as inhibitors of histone acetyltransferases (HATs)Furdas, S. D. / Hoffmann, I. / Robaa, D. / Herquel, B. / Malinka, W. / Świątek, P. / Akhtar, A. / Sippl, W. / Jung, M. et al. | 2014
- 1863
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3,5-Diamino-1,2,4-triazoles as a novel scaffold for potent, reversible LSD1 (KDM1A) inhibitorsKutz, Craig J. / Holshouser, Steven L. / Marrow, Ethan A. / Woster, Patrick M. et al. | 2014
- 1871
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Design and chemoproteomic functional characterization of a chemical probe targeted to bromodomains of BET family proteinsWu, Jiang / Shin, Julia / Williams, Cara M. M. / Geoghegan, Kieran F. / Wright, Stephen W. / Limburg, David C. / Sahasrabudhe, Parag / Bonin, Paul D. / Lefker, Bruce A. / Ramsey, Simeon J. et al. | 2014
- 1879
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Optimisation of a triazolopyridine based histone demethylase inhibitor yields a potent and selective KDM2A (FBXL11) inhibitorEngland, Katherine S. / Tumber, Anthony / Krojer, Tobias / Scozzafava, Giuseppe / Ng, Stanley S. / Daniel, Michelle / Szykowska, Aleksandra / Che, KaHing / von Delft, Frank / Burgess-Brown, Nicola A. et al. | 2014
- 1887
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Design, synthesis, and preliminary bioactivity studies of substituted purine hydroxamic acid derivatives as novel histone deacetylase (HDAC) inhibitorsWang, Junhua / Sun, Feng'e / Han, Leiqiang / Hou, Xuben / Pan, Xiaole / Liu, Renshuai / Tang, Weiping / Fang, Hao et al. | 2014
- 1892
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Structure–activity relationship studies of SETD8 inhibitorsMa, Anqi / Yu, Wenyu / Xiong, Yan / Butler, Kyle V. / Brown, Peter J. / Jin, Jian et al. | 2014
- 1899
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Back cover| 2014