Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor (English)
- New search for: Choo, Edna F.
- New search for: Belvin, Marcia
- New search for: Chan, Jocelyn
- New search for: Hoeflich, Klaus
- New search for: Orr, Christine
- New search for: Robarge, Kirk
- New search for: Yang, Xiaoye
- New search for: Zak, Mark
- New search for: Boggs, Jason
- New search for: Choo, Edna F.
- New search for: Belvin, Marcia
- New search for: Chan, Jocelyn
- New search for: Hoeflich, Klaus
- New search for: Orr, Christine
- New search for: Robarge, Kirk
- New search for: Yang, Xiaoye
- New search for: Zak, Mark
- New search for: Boggs, Jason
In:
Xenobiotica
;
40
, 11
;
751-762
;
2010
- Article (Journal) / Electronic Resource
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Title:Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitor
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Contributors:Choo, Edna F. ( author ) / Belvin, Marcia ( author ) / Chan, Jocelyn ( author ) / Hoeflich, Klaus ( author ) / Orr, Christine ( author ) / Robarge, Kirk ( author ) / Yang, Xiaoye ( author ) / Zak, Mark ( author ) / Boggs, Jason ( author )
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Published in:Xenobiotica ; 40, 11 ; 751-762
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Publisher:
- New search for: Taylor & Francis
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Publication date:2010-11-01
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Size:12 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 40, Issue 11
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 721
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In vitro assessment of metabolic drug–drug interaction potential of AZD2624, neurokinin-3 receptor antagonist, through cytochrome P450 enzyme identification, inhibition, and induction studiesLi, Yan / Zhou, Diansong / Ferguson, Stephen S. / Dorff, Peter / Simpson, Thomas R. / Grimm, Scott W. et al. | 2010
- 730
-
Pharmacokinetics and elucidation of the rates and routes of N-glucuronidation of PF-592379, an oral dopamine 3 agonist in rat, dog, and humanAttkins, Neil / Betts, Alison / Hepworth, David / Heatherington, Anne C. et al. | 2010
- 743
-
Pharmacokinetics of fexofenadine following LPS administration to ratsJaisue, S. / Gerber, J.P. / Davey, A.K. et al. | 2010
- 751
-
Preclinical disposition and pharmacokinetics-pharmacodynamic modeling of biomarker response and tumour growth inhibition in xenograft mouse models of G-573, a MEK inhibitorChoo, Edna F. / Belvin, Marcia / Chan, Jocelyn / Hoeflich, Klaus / Orr, Christine / Robarge, Kirk / Yang, Xiaoye / Zak, Mark / Boggs, Jason et al. | 2010
- 763
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Mitochondrial/lysosomal toxic cross-talk plays a key role in cisplatin nephrotoxicityPourahmad, Jalal / Hosseini, Mir-Jamal / Eskandari, Mohammad Reza / Shekarabi, Seyed Mohammad / Daraei, Bahram et al. | 2010
- 772
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Cyclosporine-induced changes in drug metabolizing enzymes in hyperlipemic rabbit kidneys could explain its toxicityElbarbry, Fawzy / Ragheb, Ahmed / Attia, Ahmed / Chibbar, Rajni / Marfleet, Travis / Shoker, Ahmed et al. | 2010
- 782
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Influence of drug-transporter polymorphisms on the pharmacokinetics of fexofenadine enantiomersAkamine, Yumiko / Miura, Masatomo / Sunagawa, Satoko / Kagaya, Hideaki / Yasui-Furukori, Norio / Uno, Tsukasa et al. | 2010