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The Number of women discovered with cancer simultaneously in both breasts appears to be increasing and such bilateral cancers tend to be multicentric, according to a West German research group. A Harjanto Tulusan, M.D. and his colleagues at Erlangen, West Germany, have examined tissue from both breasts of 1048 patients at Frauenklinik der Universitaet, 16,7 % of whom had a simultaneous cancer and another 10 % of whom had typical proliferative mastopathy in their opposite breasts. All women in the West German study had bilateral mammography before surgery. Biopsy sites were determined by mammographic and/or clinical findings, such as microcalcifications or asymmetrical thickening. If such indications were absent, Tulusan said, random biopsies were usually performed in the upper outer quadrant of the opposite breast.