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Operation optimization problem of capacitated assembly manufacturing supply chain was investigated in this paper. Three-stage system open equations of all planning periods were set up. Acceptable delivery time for customers form time window that was also considered as constraint on assembly system supply chain. The planning time is divided into many equally intervals, and operation decisions of every period can vary with time. Ability constraint in the process of supply chain operation, delivery time constraints and different production components’ quantity ratio constrain were all considered in the dynamic operation optimization model. Optimization problem is solved by hybrid mixed integral optimization and SQP algorithm. And a set of numerical examples that reveal the insights into the dynamic optimization policy.