The relationship between first‐degree family history of dementia, tau pathology and functional impairment among brain donors at risk for chronic traumatic encephalopathy (English)
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In:
Alzheimer's & Dementia
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17
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2021
- Article (Journal) / Electronic Resource
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Title:The relationship between first‐degree family history of dementia, tau pathology and functional impairment among brain donors at risk for chronic traumatic encephalopathy
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Contributors:Nair, Evan S ( author ) / Burton, Rebecca ( author ) / Abdolmohammadi, Bobak ( author ) / Saltiel, Nicole ( author ) / Uretsky, Madeline ( author ) / Shah, Arsal ( author ) / Baucom, Zachary H. ( author ) / Martin, Brett M ( author ) / Palmisano, Joseph ( author ) / Huber, Bertrand R. ( author )
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Published in:
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Publisher:
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Publication date:2021-12-01
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Size:1 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Source:
Table of contents – Volume 17
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1
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Issue Information| 2021
- 7
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Safety and target engagement profile of two oxaloacetate doses in Alzheimer's patientsVidoni, Eric D. / Choi, In‐Young / Lee, Phil / Reed, Gregory / Zhang, Na / Pleen, Joseph / Mahnken, Jonathan D. / Clutton, Jonathan / Becker, Annette / Sherry, Erica et al. | 2021
- 18
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Lifestyle, multi‐omics features, and preclinical dementia among Chinese: The Taizhou Imaging StudyJiang, Yanfeng / Cui, Mei / Tian, Weizhong / Zhu, Sibo / Chen, Jinhua / Suo, Chen / Liu, Zhenqiu / Lu, Ming / Xu, Kelin / Fan, Min et al. | 2021
- 29
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36‐month LipiDiDiet multinutrient clinical trial in prodromal Alzheimer's diseaseSoininen, Hilkka / Solomon, Alina / Visser, Pieter Jelle / Hendrix, Suzanne B / Blennow, Kaj / Kivipelto, Miia / Hartmann, Tobias / the LipiDiDiet clinical study group et al. | 2021
- 41
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Drug therapies for chronic conditions and risk of Alzheimer's disease and related dementias: A scoping reviewThunell, Johanna / Chen, Yi / Joyce, Geoffrey / Barthold, Douglas / Shekelle, Paul G. / Brinton, Roberta Diaz / Zissimopoulos, Julie et al. | 2021
- 49
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Blood neuro‐exosomal synaptic proteins predict Alzheimer's disease at the asymptomatic stageJia, Longfei / Zhu, Min / Kong, Chaojun / Pang, Yana / Zhang, Heng / Qiu, Qiongqiong / Wei, Cuibai / Tang, Yi / Wang, Qi / Li, Ying et al. | 2021
- 61
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APOE interacts with tau PET to influence memory independently of amyloid PET in older adults without dementiaWeigand, Alexandra J. / Thomas, Kelsey R. / Bangen, Katherine J. / Eglit, Graham M.L. / Delano‐Wood, Lisa / Gilbert, Paul E. / Brickman, Adam M. / Bondi, Mark W. / for the Alzheimer's Disease Neuroimaging Initiative et al. | 2021
- 70
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Education differentially contributes to cognitive reserve across racial/ethnic groupsAvila, Justina F. / Rentería, Miguel Arce / Jones, Richard N. / Vonk, Jet M. J. / Turney, Indira / Sol, Ketlyne / Seblova, Dominika / Arias, Franchesca / Hill‐Jarrett, Tanisha / Levy, Shellie‐Anne et al. | 2021
- 81
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Epidemiology of early onset dementia and its clinical presentations in the province of Modena, ItalyChiari, Annalisa / Vinceti, Giulia / Adani, Giorgia / Tondelli, Manuela / Galli, Chiara / Fiondella, Luigi / Costa, Manuela / Molinari, Maria A. / Filippini, Tommaso / Zamboni, Giovanna et al. | 2021
- 89
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The Brain Chart of Aging: Machine‐learning analytics reveals links between brain aging, white matter disease, amyloid burden, and cognition in the iSTAGING consortium of 10,216 harmonized MR scansHabes, Mohamad / Pomponio, Raymond / Shou, Haochang / Doshi, Jimit / Mamourian, Elizabeth / Erus, Guray / Nasrallah, Ilya / Launer, Lenore J. / Rashid, Tanweer / Bilgel, Murat et al. | 2021
- 103
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Retinal imaging in Alzheimer's and neurodegenerative diseasesSnyder, Peter J. / Alber, Jessica / Alt, Clemens / Bain, Lisa J. / Bouma, Brett E. / Bouwman, Femke H. / DeBuc, Delia Cabrera / Campbell, Melanie C.W. / Carrillo, Maria C. / Chew, Emily Y. et al. | 2021
- 112
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Alzheimer's team care approach—akin to diabetes—in the development, validation, and population assessment of retinal biomarkers for diseaseDueñas, Michael R. / Snyder, Peter J. et al. | 2021
- 115
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Hypothesis: Tau pathology is an initiating factor in sporadic Alzheimer's diseaseArnsten, Amy F. T. / Datta, Dibyadeep / Del Tredici, Kelly / Braak, Heiko et al. | 2021
- 125
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Unexpected awakenings in severe dementia from case reports to laboratoryBostanciklioğlu, Mehmet et al. | 2021
- 137
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Erratum| 2021
- 138
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Alzheimer's Association International Conference Neuroscience Next focused on early career researchers across all of neuroscience| 2021
- 149
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Reactive or transgenic increase in microglial TYROBP reveals a TREM2‐independent TYROBP–APOE link in wild‐type and Alzheimer's‐related miceAudrain, Mickael / Haure‐Mirande, Jean‐Vianney / Mleczko, Justyna / Wang, Minghui / Griffin, Jennifer K. / St George‐Hyslop, Peter H. / Fraser, Paul / Zhang, Bin / Gandy, Sam / Ehrlich, Michelle E. et al. | 2021
- 164
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ABCA7 and the altered lipidostasis hypothesis of Alzheimer's diseaseLyssenko, Nicholas N. / Praticò, Domenico et al. | 2021
- 175
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The APOE gene cluster responds to air pollution factors in mice with coordinated expression of genes that differs by age in humansHaghani, Amin / Thorwald, Max / Morgan, Todd E. / Finch, Caleb E. et al. | 2021
- 191
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Shared risk and protective factors between Alzheimer's disease and ischemic stroke: A population‐based longitudinal studyWang, Rui / Qiu, Chengxuan / Dintica, Christina S. / Shang, Ying / Calderón Larrañaga, Amaia / Wang, Hui‐Xin / Xu, Weili et al. | 2021
- 205
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Circulating metabolites are associated with brain atrophy and white matter hyperintensitiesde Leeuw, Francisca A. / Karamujić‐Čomić, Hata / Tijms, Betty M. / Peeters, Carel F.W. / Kester, Maartje I. / Scheltens, Philip / Ahmad, Shahzad / Vojinovic, Dina / Adams, Hieab H.H. / Hankemeier, Thomas et al. | 2021
- 215
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Non‐coding variants in MYH11, FZD3, and SORCS3 are associated with dementia in womenBlue, Elizabeth E. / Thornton, Timothy A. / Kooperberg, Charles / Liu, Simin / Wactawski‐Wende, Jean / Manson, JoAnn / Kuller, Lew / Hayden, Kathleen / Reiner, Alexander P. et al. | 2021
- 226
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Self‐reported obstructive sleep apnea, amyloid and tau burden, and Alzheimer's disease time‐dependent progressionBubu, Omonigho M. / Umasabor‐Bubu, Ogie Q. / Turner, Arlener D / Parekh, Ankit / Mullins, Anna E. / Kam, Korey / Birckbichler, Madeline K. / Mukhtar, Fahad / Mbah, Alfred K / Williams, Natasha J. et al. | 2021
- 246
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Recognizing African‐American contributions to neurology: The role of Solomon Carter Fuller (1872–1953) in Alzheimer's disease researchMohammed, Hamzah et al. | 2021
- 251
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Are we measuring the same thing? Psychometric and research considerations when adopting new testing modes in the time of COVID‐19Booth, Tom / Murray, Aja / Muniz‐Terrera, Graciela et al. | 2021
- 255
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Toward a theory‐based specification of non‐pharmacological treatments in aging and dementia: Focused reviews and methodological recommendationsSikkes, Sietske A.M. / Tang, Yi / Jutten, Roos J. / Wesselman, Linda M.P. / Turkstra, Lyn S. / Brodaty, Henry / Clare, Linda / Cassidy‐Eagle, Erin / Cox, Kay L. / Chételat, Gaël et al. | 2021
- 271
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Targeting increased levels of APP in Down syndrome: Posiphen‐mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse modelChen, Xu‐Qiao / Salehi, Ahmad / Pearn, Matthew L. / Overk, Cassia / Nguyen, Phuong D. / Kleschevnikov, Alexander M. / Maccecchini, Maria / Mobley, William C. et al. | 2021
- 295
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Dementia in Latin America: Paving the way toward a regional action planParra, Mario Alfredo / Baez, Sandra / Sedeño, Lucas / Gonzalez Campo, Cecilia / Santamaría‐García, Hernando / Aprahamian, Ivan / Bertolucci, Paulo HF / Bustin, Julian / Camargos Bicalho, Maria Aparecida / Cano‐Gutierrez, Carlos et al. | 2021
- 314
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Synaptic impairment: The new battlefield of Alzheimer's diseaseFrancesco, Di Lorenzo / Koch, Giacomo et al. | 2021
- 316
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Alzheimer's & Dementia: The Journal of the Alzheimer's AssociationMecca, Adam P. / van Dyck, Christopher H. et al. | 2021
- 318
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Alzheimer's Association Update| 2021
- 327
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2021 Alzheimer's disease facts and figures| 2021
- 407
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Blood polyunsaturated omega‐3 fatty acids, brain atrophy, cognitive decline, and dementia riskThomas, Aline / Baillet, Marion / Proust‐Lima, Cécile / Féart, Catherine / Foubert‐Samier, Alexandra / Helmer, Catherine / Catheline, Gwénaëlle / Samieri, Cécilia et al. | 2021
- 417
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Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathologyHou, Xu / Watzlawik, Jens O. / Cook, Casey / Liu, Chia‐Chen / Kang, Silvia S. / Lin, Wen‐Lang / DeTure, Michael / Heckman, Michael G. / Diehl, Nancy N. / Al‐Shaikh, Fadi S. Hanna et al. | 2021
- 431
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An examination of a novel multipanel of CSF biomarkers in the Alzheimer's disease clinical and pathological continuumVan Hulle, Carol / Jonaitis, Erin M. / Betthauser, Tobey J. / Batrla, Richard / Wild, Norbert / Kollmorgen, Gwendlyn / Andreasson, Ulf / Okonkwo, Ozioma / Bendlin, Barbara B. / Asthana, Sanjay et al. | 2021
- 446
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Immunity and amyloid beta, total tau and neurofilament light chain: Findings from a community‐based cohort studyFani, Lana / Ahmad, Shahzad / Ikram, M. Kamran / Ghanbari, Mohsen / Ikram, M. Arfan et al. | 2021
- 457
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Gene‐ and age‐informed screening for preclinical Alzheimer's disease trialsSpencer, Barbara E. / Digma, Leonardino A. / Jennings, Robin G. / Brewer, James B. / for the Alzheimer's Disease Neuroimaging Initiative and the A4 Study Team et al. | 2021
- 466
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APOE alleles’ association with cognitive function differs across Hispanic/Latino groups and genetic ancestry in the study of Latinos‐investigation of neurocognitive aging (HCHS/SOL)Granot‐Hershkovitz, Einat / Tarraf, Wassim / Kurniansyah, Nuzulul / Daviglus, Martha / Isasi, Carmen R. / Kaplan, Robert / Lamar, Melissa / Perreira, Krista M. / Wassertheil‐Smoller, Sylvia / Stickel, Ariana et al. | 2021
- 475
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Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1‐42Kober, Daniel L. / Stuchell‐Brereton, Melissa D. / Kluender, Colin E. / Dean, Hunter B. / Strickland, Michael R. / Steinberg, Deborah F. / Nelson, Samantha S. / Baban, Berevan / Holtzman, David M. / Frieden, Carl et al. | 2021
- 489
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Long genes are more frequently affected by somatic mutations and show reduced expression in Alzheimer's disease: Implications for disease etiologySoheili‐Nezhad, Sourena / van der Linden, Robert J. / Olde Rikkert, Marcel / Sprooten, Emma / Poelmans, Geert et al. | 2021
- 500
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Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementiaTsvetanov, Kamen A. / Gazzina, Stefano / Jones, P. Simon / van Swieten, John / Borroni, Barbara / Sanchez‐Valle, Raquel / Moreno, Fermin / Laforce, Robert Jr / Graff, Caroline / Synofzik, Matthis et al. | 2021
- 515
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Using Medicare claims in identifying Alzheimer's disease and related dementiasJain, Siddharth / Rosenbaum, Paul R. / Reiter, Joseph G. / Hoffman, Geoffrey / Small, Dylan S. / Ha, Jinkyung / Hill, Alexander S. / Wolk, David A. / Gaulton, Timothy / Neuman, Mark D. et al. | 2021
- 525
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Long‐term community noise exposure in relation to dementia, cognition, and cognitive decline in older adultsWeuve, Jennifer / D'Souza, Jennifer / Beck, Todd / Evans, Denis A. / Kaufman, Joel D. / Rajan, Kumar. B. / de Leon, Carlos F. Mendes / Adar, Sara D. et al. | 2021
- 534
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Item response theory analysis of the Clinical Dementia RatingLi, Yan / Xiong, Chengjie / Aschenbrenner, Andrew J. / Chang, Chih‐Hung / Weiner, Michael W / Nosheny, Rachel L / Mungas, Dan / Bateman, Randall J / Hassenstab, Jason / Moulder, Krista L et al. | 2021
- 543
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A ketogenic drink improves cognition in mild cognitive impairment: Results of a 6‐month RCTFortier, Mélanie / Castellano, Christian‐Alexandre / St‐Pierre, Valérie / Myette‐Côté, Étienne / Langlois, Francis / Roy, Maggie / Morin, Marie‐Christine / Bocti, Christian / Fulop, Tamas / Godin, Jean‐Philippe et al. | 2021
- 561
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Likelihood ratio statistics for gene set enrichment in Alzheimer's disease pathwaysBryan, Jordan / Mandan, Arpita / Kamat, Gauri / Gottschalk, W. Kirby / Badea, Alexandra / Adams, Kendra J. / Thompson, J. Will / Colton, Carol A. / Mukherjee, Sayan / Lutz, Michael W. et al. | 2021
- 574
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Development and validation of the Uniform Data Set (v3.0) executive function composite score (UDS3‐EF)Staffaroni, Adam M. / Asken, Breton M. / Casaletto, Kaitlin B. / Fonseca, Corrina / You, Michelle / Rosen, Howard J. / Boxer, Adam L. / Elahi, Fanny M. / Kornak, John / Mungas, Dan et al. | 2021
- 584
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Diagnostic accuracy of the Cogstate Brief Battery for prevalent MCI and prodromal AD (MCI A+T+) in a population‐based sampleAlden, Eva C. / Pudumjee, Shehroo B. / Lundt, Emily S. / Albertson, Sabrina M. / Machulda, Mary M. / Kremers, Walter K. / Jack, Clifford R. Jr / Knopman, David S. / Petersen, Ronald C. / Mielke, Michelle M. et al. | 2021
- 595
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Optimal age and outcome measures for Alzheimer's disease prevention trials in people with Down syndromeHithersay, Rosalyn / Baksh, R. Asaad / Startin, Carla M. / Wijeratne, Peter / Hamburg, Sarah / Carter, Ben / Strydom, Andre / The LonDownS Consortium et al. | 2021
- 605
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Nerve growth factor (NGF) pathway biomarkers in Down syndrome prior to and after the onset of clinical Alzheimer's disease: A paired CSF and plasma studyPentz, Rowan / Iulita, M. Florencia / Ducatenzeiler, Adriana / Videla, Laura / Benejam, Bessy / Carmona‐Iragui, María / Blesa, Rafael / Lleó, Alberto / Fortea, Juan / Cuello, A. Claudio et al. | 2021
- 618
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Biphasic cortical macro‐ and microstructural changes in autosomal dominant Alzheimer's diseaseMontal, Victor / Vilaplana, Eduard / Pegueroles, Jordi / Bejanin, Alexandre / Alcolea, Daniel / Carmona‐Iragui, María / Clarimón, Jordi / Levin, Johannes / Cruchaga, Carlos / Graff‐Radford, Neill R. et al. | 2021
- 629
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Plasma β‐secretase1 concentrations correlate with basal forebrain atrophy and neurodegeneration in cognitively healthy individuals at risk for ADVergallo, Andrea / Lemercier, Pablo / Cavedo, Enrica / Lista, Simone / Vanmechelen, Eugeen / De Vos, Ann / Zetterberg, Henrik / Blennow, Kaj / Habert, Marie‐Odile / Potier, Marie‐Claude et al. | 2021
- 641
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Clinical relevance of brain atrophy subtypes categorization in memory clinicsPlanche, Vincent / Bouteloup, Vincent / Mangin, Jean‐François / Dubois, Bruno / Delrieu, Julien / Pasquier, Florence / Blanc, Frédéric / Paquet, Claire / Hanon, Olivier / Gabelle, Audrey et al. | 2021
- 653
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Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypesLlibre‐Guerra, Jorge J. / Li, Yan / Allegri, Ricardo F. / Mendez, Patricio Chrem / Surace, Ezequiel I. / Llibre‐Rodriguez, Juan J. / Sosa, Ana Luisa / Aláez‐Verson, Carmen / Longoria, Erika‐Mariana / Tellez, Alberto et al. | 2021
- 665
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Cognitive impairment in sporadic cerebral small vessel disease: A systematic review and meta‐analysisHamilton, Olivia K. L. / Backhouse, Ellen V. / Janssen, Esther / Jochems, Angela C. C. / Maher, Caragh / Ritakari, Tuula E. / Stevenson, Anna J. / Xia, Lihua / Deary, Ian J. / Wardlaw, Joanna M. et al. | 2021
- 686
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Traumatic brain injury alters neuropsychiatric symptomatology in all‐cause dementiaBray, Michael J. C. / Richey, Lisa N. / Bryant, Barry R. / Krieg, Akshay / Jahed, Sahar / Tobolowsky, William / LoBue, Christian / Peters, Matthew E. et al. | 2021
- 692
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ENGAGE and EMERGE: Truth and consequences?Kuller, Lewis H. / Lopez, Oscar L. et al. | 2021
- 696
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Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019Knopman, David S. / Jones, David T. / Greicius, Michael D. et al. | 2021
- 702
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Open Peer Commentary to “Failure to demonstrate efficacy of aducanumab: An analysis of the EMERGE and ENGAGE Trials as reported by Biogen December 2019”Sabbagh, Marwan Noel / Cummings, Jeffrey et al. | 2021
- 704
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MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocolsWilcock, Donna / Jicha, Gregory / Blacker, Deborah / Albert, Marilyn S. / D'Orazio, Lina M. / Elahi, Fanny M. / Fornage, Myriam / Hinman, Jason D. / Knoefel, Janice / Kramer, Joel et al. | 2021
- 716
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MarkVCID cerebral small vessel consortium: II. Neuroimaging protocolsLu, Hanzhang / Kashani, Amir H. / Arfanakis, Konstantinos / Caprihan, Arvind / DeCarli, Charles / Gold, Brian T. / Li, Yang / Maillard, Pauline / Satizabal, Claudia L. / Stables, Lara et al. | 2021
- 726
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Register for May AAIC® Satellite Symposium and second Latinos & Alzheimer's symposium| 2021
- 733
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Diet, psychosocial stress, and Alzheimer's disease–related neuroanatomy in female nonhuman primatesFrye, Brett M. / Craft, Suzanne / Register, Thomas C. / Andrews, Rachel N. / Appt, Susan E. / Vitolins, Mara Z. / Uberseder, Beth / Silverstein‐Metzler, Marnie G. / Chen, Haiying / Whitlow, Christopher T. et al. | 2021
- 745
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Vascular health across young adulthood and midlife cerebral autoregulation, gait, and cognitionMahinrad, Simin / Shownkeen, Meghana / Sedaghat, Sanaz / Yaffe, Kristine / Hausdorff, Jeffrey M. / Lloyd‐Jones, Donald M. / Gorelick, Philip B. / Sorond, Farzaneh A. et al. | 2021
- 755
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Head‐to‐head comparison of clinical performance of CSF phospho‐tau T181 and T217 biomarkers for Alzheimer's disease diagnosisKarikari, Thomas K. / Emeršič, Andreja / Vrillon, Agathe / Lantero‐Rodriguez, Juan / Ashton, Nicholas J. / Kramberger, Milica Gregorič / Dumurgier, Julien / Hourregue, Claire / Čučnik, Saša / Brinkmalm, Gunnar et al. | 2021
- 768
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Multimorbidity burden and dementia risk in older adults: The role of inflammation and geneticsGrande, Giulia / Marengoni, Alessandra / Vetrano, Davide L. / Roso‐Llorach, Albert / Rizzuto, Debora / Zucchelli, Alberto / Qiu, Chengxuan / Fratiglioni, Laura / Calderón‐Larrañaga, Amaia et al. | 2021
- 777
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Brain structures and networks responsible for stimulation‐induced memory flashbacks during forniceal deep brain stimulation for Alzheimer's diseaseGermann, Jürgen / Elias, Gavin J.B. / Boutet, Alexandre / Narang, Keshav / Neudorfer, Clemens / Horn, Andreas / Loh, Aaron / Deeb, Wissam / Salvato, Bryan / Almeida, Leonardo et al. | 2021
- 788
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Cerebral amyloid‐β load is associated with neurodegeneration and gliosis: Mediation by p‐tau and interactions with risk factors early in the Alzheimer's continuumSalvadó, Gemma / Milà‐Alomà, Marta / Shekari, Mahnaz / Minguillon, Carolina / Fauria, Karine / Niñerola‐Baizán, Aida / Perissinotti, Andrés / Kollmorgen, Gwendlyn / Buckley, Christopher / Farrar, Gill et al. | 2021
- 801
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Comparison of CSF neurofilament light chain, neurogranin, and tau to MRI markersMielke, Michelle M. / Przybelski, Scott A. / Lesnick, Timothy G. / Kern, Silke / Zetterberg, Henrik / Blennow, Kaj / Knopman, David S. / Graff‐Radford, Jonathan / Petersen, Ronald C. / Jack, Clifford R. Jr. et al. | 2021
- 813
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Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non‐demented individuals with autosomal‐dominant Alzheimer's diseaseGuzmán‐Vélez, Edmarie / Zetterberg, Henrik / Fox‐Fuller, Joshua T. / Vila‐Castelar, Clara / Sanchez, Justin S. / Baena, Ana / Garcia‐Ospina, Gloria / Aguillon, David / Pardilla‐Delgado, Enmanuelle / Gatchel, Jennifer R. et al. | 2021
- 822
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ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degenerationCousins, Katheryn A.Q. / Phillips, Jeffrey S. / Irwin, David J. / Lee, Edward B. / Wolk, David A. / Shaw, Leslie M. / Zetterberg, Henrik / Blennow, Kaj / Burke, Sarah E. / Kinney, Nikolas G. et al. | 2021
- 831
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Harnessing the paradoxical phenotypes of APOE ɛ2 and APOE ɛ4 to identify genetic modifiers in Alzheimer's diseaseKim, Young Won / Al‐Ramahi, Ismael / Koire, Amanda / Wilson, Stephen J. / Konecki, Daniel M. / Mota, Samantha / Soleimani, Shirin / Botas, Juan / Lichtarge, Olivier et al. | 2021
- 847
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Utility of MRI in the identification of hippocampal sclerosis of agingWoodworth, Davis C. / Nguyen, Hannah L. / Khan, Zainab / Kawas, Claudia H. / Corrada, María M. / Sajjadi, S. Ahmad et al. | 2021
- 856
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The Clinician's Interview‐Based Impression of Change (Plus caregiver input) and goal attainment in two dementia drug trials: Clinical meaningfulness and the initial treatment responseStanley, Justin / Howlett, Susan E. / Dunn, Taylor / Rockwood, Kenneth et al. | 2021
- 866
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The search for a convenient procedure to detect one of the earliest signs of Alzheimer's disease: A systematic review of the prediction of brain amyloid statusAshford, Miriam T. / Veitch, Dallas P. / Neuhaus, John / Nosheny, Rachel L. / Tosun, Duygu / Weiner, Michael W. et al. | 2021
- 888
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Endogenous antagonists of N‐methyl‐d‐aspartate receptor in schizophreniaJorratt, Pascal / Hoschl, Cyril / Ovsepian, Saak V. et al. | 2021
- 910
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Association commits $14 million to novel drug trials in rare form of Alzheimer's| 2021
- 917
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How Bayesian statistics may help answer some of the controversial questions in clinical research on Alzheimer's diseaseTemp, Anna G. M. / Lutz, Michael W. / Trepel, Dominic / Tang, Yi / Wagenmakers, Eric‐Jan / Khachaturian, Ara S. / Teipel, Stefan et al. | 2021
- 920
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Age‐related calcium dysregulation linked with tau pathology and impaired cognition in non‐human primatesDatta, Dibyadeep / Leslie, Shannon N. / Wang, Min / Morozov, Yury M. / Yang, Shengtao / Mentone, SueAnn / Zeiss, Caroline / Duque, Alvaro / Rakic, Pasko / Horvath, Tamas L. et al. | 2021
- 933
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A novel tau‐based rhesus monkey model of Alzheimer's pathogenesisBeckman, Danielle / Chakrabarty, Paramita / Ott, Sean / Dao, Amanda / Zhou, Eric / Janssen, William G. / Donis‐Cox, Kristine / Muller, Scott / Kordower, Jeffrey H. / Morrison, John H. et al. | 2021
- 946
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Sequence of proteome profiles in preclinical and symptomatic Alzheimer's diseaseLi, Xiaohang / Tsolis, Konstantinos C. / Koper, Marta J. / Ronisz, Alicja / Ospitalieri, Simona / von Arnim, Christine A.F. / Vandenberghe, Rik / Tousseyn, Thomas / Scheuerle, Angelika / Economou, Anastassios et al. | 2021
- 959
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Actigraphic sleep patterns and cognitive decline in the Hispanic Community Health Study/Study of LatinosAgudelo, Christian / Tarraf, Wassim / Wu, Benson / Wallace, Douglas M. / Patel, Sanjay R. / Redline, Susan / Kaur, Sonya / Daviglus, Martha / Zee, Phyllis C. / Simonelli, Guido et al. | 2021
- 969
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Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changesMalpetti, Maura / Jones, P. Simon / Tsvetanov, Kamen A. / Rittman, Timothy / van Swieten, John C. / Borroni, Barbara / Sanchez‐Valle, Raquel / Moreno, Fermin / Laforce, Robert / Graff, Caroline et al. | 2021
- 984
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Integrative functional genomic analysis of intron retention in human and mouse brain with Alzheimer's diseaseLi, Hong‐Dong / Funk, Cory C. / McFarland, Karen / Dammer, Eric B. / Allen, Mariet / Carrasquillo, Minerva M. / Levites, Yona / Chakrabarty, Paramita / Burgess, Jeremy D. / Wang, Xue et al. | 2021
- 1005
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Modeling autosomal dominant Alzheimer's disease with machine learningLuckett, Patrick H. / McCullough, Austin / Gordon, Brian A. / Strain, Jeremy / Flores, Shaney / Dincer, Aylin / McCarthy, John / Kuffner, Todd / Stern, Ari / Meeker, Karin L. et al. | 2021
- 1017
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MRI‐assessed locus coeruleus integrity is heritable and associated with multiple cognitive domains, mild cognitive impairment, and daytime dysfunctionElman, Jeremy A. / Puckett, Olivia K. / Beck, Asad / Fennema‐Notestine, Christine / Cross, Latonya K. / Dale, Anders M. / Eglit, Graham M. L. / Eyler, Lisa T. / Gillespie, Nathan A. / Granholm, Eric L. et al. | 2021
- 1026
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The economic cost of delirium: A systematic review and quality assessmentKinchin, Irina / Mitchell, Eileen / Agar, Meera / Trépel, Dominic et al. | 2021
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The risk of dementia after coronary artery bypass grafting in relation to age and sexGiang, Kok Wai / Jeppsson, Anders / Karlsson, Martin / Hansson, Emma C. / Pivodic, Aldina / Skoog, Ingmar / Lindgren, Martin / Nielsen, Susanne J. et al. | 2021
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Bayes analysis supports null hypothesis of anti‐amyloid beta therapy in Alzheimer's diseaseRichard, Edo / den Brok, Melina G.H.E. / van Gool, Willem A. et al. | 2021
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The chronic neuropsychiatric sequelae of COVID‐19: The need for a prospective study of viral impact on brain functioningde Erausquin, Gabriel A. / Snyder, Heather / Carrillo, María / Hosseini, Akram A. / Brugha, Traolach S. / Seshadri, Sudha / the CNS SARS‐CoV‐2 Consortium et al. | 2021
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Traditional Chinese medicine for dementiaLi, Song / Wu, Zhengzhi / Le, Weidong et al. | 2021
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Stroke and dementia, leading causes of neurological disability and death, potential for preventionAvan, Abolfazl / Hachinski, Vladimir et al. | 2021
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Organizations join forces to support early diagnosis of Lewy body dementia| 2021
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Distinct effects of beta‐amyloid and tau on cortical thickness in cognitively healthy older adultsHarrison, Theresa M. / Du, Richard / Klencklen, Giuliana / Baker, Suzanne L. / Jagust, William J. et al. | 2021
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Increased β‐site APP cleaving enzyme 1‐mediated insulin receptor cleavage in type 2 diabetes mellitus with cognitive impairmentBao, Hong / Liu, Yiming / Zhang, Mengguo / Chen, Zuolong / Zhang, Weiwei / Ge, Yuhao / Kang, Dongmei / Gao, Feng / Shen, Yong et al. | 2021
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CVN‐AD Alzheimer's mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia compared to aged controlsTurner, Dennis A. / Degan, Simone / Hoffmann, Ulrike / Galeffi, Francesca / Colton, Carol A. et al. | 2021
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Concomitant neurodegenerative pathologies contribute to the transition from mild cognitive impairment to dementiaMcAleese, Kirsty E. / Colloby, Sean J. / Thomas, Alan J. / Al‐Sarraj, Safa / Ansorge, Olaf / Neal, James / Roncaroli, Federico / Love, Seth / Francis, Paul T. / Attems, Johannes et al. | 2021
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Lower complexity and higher variability in beat‐to‐beat systolic blood pressure are associated with elevated long‐term risk of dementia: The Rotterdam StudyMa, Yuan / Zhou, Junhong / Kavousi, Maryam / Lipsitz, Lewis A. / Mattace‐Raso, Francesco / Westerhof, Berend E. / Wolters, Frank J. / Wu, Julia W. / Manor, Brad / Ikram, M. Kamran et al. | 2021
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The diagnostic and prognostic capabilities of plasma biomarkers in Alzheimer's diseaseSimrén, Joel / Leuzy, Antoine / Karikari, Thomas K. / Hye, Abdul / Benedet, Andréa Lessa / Lantero‐Rodriguez, Juan / Mattsson‐Carlgren, Niklas / Schöll, Michael / Mecocci, Patrizia / Vellas, Bruno et al. | 2021
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Unhealthy foods may attenuate the beneficial relation of a Mediterranean diet to cognitive declineAgarwal, Puja / Dhana, Klodian / Barnes, Lisa L. / Holland, Thomas M / Zhang, Yanyu / Evans, Denis A. / Morris, Martha Clare et al. | 2021
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Sex differences in dementia and response to a lifestyle intervention: Evidence from Nordic population‐based studies and a prevention trialSindi, Shireen / Kåreholt, Ingemar / Ngandu, Tiia / Rosenberg, Anna / Kulmala, Jenni / Johansson, Lena / Wetterberg, Hanna / Skoog, Johan / Sjöberg, Linnea / Wang, Hui‐Xin et al. | 2021
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Increased APOE ε4 expression is associated with the difference in Alzheimer's disease risk from diverse ancestral backgroundsGriswold, Anthony J. / Celis, Katrina / Bussies, Parker L. / Rajabli, Farid / Whitehead, Patrice L. / Hamilton‐Nelson, Kara L. / Beecham, Gary W. / Dykxhoorn, Derek M. / Nuytemans, Karen / Wang, Liyong et al. | 2021
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Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohortIngala, Silvia / De Boer, Casper / Masselink, Larissa A / Vergari, Ilaria / Lorenzini, Luigi / Blennow, Kaj / Chételat, Gaël / Di Perri, Carol / Ewers, Michael / van der Flier, Wiesje M et al. | 2021
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Quantifying dementia prevention potential in the FINGER randomized controlled trial using the LIBRA prevention indexDeckers, Kay / Köhler, Sebastian / Ngandu, Tiia / Antikainen, Riitta / Laatikainen, Tiina / Soininen, Hilkka / Strandberg, Timo / Verhey, Frans / Kivipelto, Miia / Solomon, Alina et al. | 2021
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Rural‐urban differences in diagnostic incidence and prevalence of Alzheimer's disease and related dementiasRahman, Momotazur / White, Elizabeth M. / Mills, Caroline / Thomas, Kali S. / Jutkowitz, Eric et al. | 2021
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Cognitive measures lacking in EHR prior to dementia or Alzheimer's disease diagnosisMaserejian, Nancy / Krzywy, Henry / Eaton, Susan / Galvin, James E. et al. | 2021
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Regional brain iron associated with deterioration in Alzheimer's disease: A large cohort study and theoretical significanceAyton, Scott / Portbury, Stuart / Kalinowski, Pawel / Agarwal, Puja / Diouf, Ibrahima / Schneider, Julie A. / Morris, Martha Clare / Bush, Ashley I. et al. | 2021
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ISTAART PIAs reflect on lessons learned from the virtual AAIC 2020| 2021
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Generalizability of findings from a clinical sample to a community‐based sample: A comparison of ADNI and ARICGianattasio, Kan Z. / Bennett, Erin E. / Wei, Jingkai / Mehrotra, Megha L. / Mosley, Thomas / Gottesman, Rebecca F. / Wong, Dean F. / Stuart, Elizabeth A. / Griswold, Michael E. / Couper, David et al. | 2021
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Associations among education, age, and the dementia with Lewy bodies (DLB) metabolic pattern: A European‐DLB consortium projectBauckneht, Matteo / Chincarini, Andrea / Brendel, Matthias / Rominger, Axel / Beyer, Leonie / Bruffaerts, Rose / Vandenberghe, Rik / Kramberger, Milica G. / Trost, Maja / Garibotto, Valentina et al. | 2021
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TOMM40‐APOE haplotypes are associated with cognitive decline in non‐demented BlacksDeters, Kacie D. / Mormino, Elizabeth C. / Yu, Lei / Lutz, Michael W. / Bennett, David A. / Barnes, Lisa L. et al. | 2021
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COVID‐19 and dementia: Analyses of risk, disparity, and outcomes from electronic health records in the USWang, QuanQiu / Davis, Pamela B. / Gurney, Mark E. / Xu, Rong et al. | 2021
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Identification of undiagnosed dementia cases using a web‐based pre‐screening tool: The MOPEAD projectRodrigo, Adrián / Trigueros, Paloma / Jamilis, Laura / Alegret, Montserrat / Rodríguez, Octavio / Tárraga, Lluís / González‐Pérez, Antonio / Kramberger, Milica / Winblad, Bengt / Visser, Pieter Jelle et al. | 2021
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Gait variability across neurodegenerative and cognitive disorders: Results from the Canadian Consortium of Neurodegeneration in Aging (CCNA) and the Gait and Brain StudyPieruccini‐Faria, Frederico / Black, Sandra E. / Masellis, Mario / Smith, Eric E. / Almeida, Quincy J. / Li, Karen Z. H. / Bherer, Louis / Camicioli, Richard / Montero‐Odasso, Manuel et al. | 2021
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Sex differences in the behavioral variant of frontotemporal dementia: A new window to executive and behavioral reserveIllán‐Gala, Ignacio / Casaletto, Kaitlin B. / Borrego‐Écija, Sergi / Arenaza‐Urquijo, Eider M. / Wolf, Amy / Cobigo, Yann / Goh, Sheng Yang M. / Staffaroni, Adam M. / Alcolea, Daniel / Fortea, Juan et al. | 2021
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Cardiovascular risk and midlife cognitive decline in the Study of Women's Health Across the NationDerby, Carol A. / Hutchins, Franya / Greendale, Gail A. / Matthews, Karen A. / Sternfeld, Barbara / Everson‐Rose, Susan A. / Kazlauskaite, Rasa / Whitmer, Rachel A. / Brooks, Maria M. et al. | 2021
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Plasma p‐tau181, p‐tau217, and other blood‐based Alzheimer's disease biomarkers in a multi‐ethnic, community studyBrickman, Adam M. / Manly, Jennifer J. / Honig, Lawrence S. / Sanchez, Danurys / Reyes‐Dumeyer, Dolly / Lantigua, Rafael A. / Lao, Patrick J. / Stern, Yaakov / Vonsattel, Jean Paul / Teich, Andrew F. et al. | 2021
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Preclinical and clinical biomarker studies of CT1812: A novel approach to Alzheimer's disease modificationIzzo, Nicholas J. / Yuede, Carla M. / LaBarbera, Kelsie M. / Limegrover, Colleen S. / Rehak, Courtney / Yurko, Raymond / Waybright, Lora / Look, Gary / Rishton, Gilbert / Safferstein, Hank et al. | 2021
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Association of life‐course depression with the risk of dementia in late life: A nationwide twin studyYang, Wenzhe / Li, Xuerui / Pan, Kuan‐Yu / Yang, Rongrong / Song, Ruixue / Qi, Xiuying / Pedersen, Nancy L. / Xu, Weili et al. | 2021
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Plasma hydrogen sulfide: A biomarker of Alzheimer's disease and related dementiasDisbrow, Elizabeth / Stokes, Karen Y. / Ledbetter, Christina / Patterson, James / Kelley, Roger / Pardue, Sibile / Reekes, Tyler / Larmeu, Lana / Batra, Vinita / Yuan, Shuai et al. | 2021
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Deepen into sleep and wake patterns across Alzheimer's disease phenotypesFalgàs, Neus / Walsh, Christine M. / Neylan, Thomas C. / Grinberg, Lea T. et al. | 2021
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Virtual conferences broadcast research advances in 2021| 2021
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Investigating the association between cancer and the risk of dementia: Results from the Memento cohortChamberlain, Jonviea D. / Rouanet, Anaïs / Dubois, Bruno / Pasquier, Florence / Hanon, Olivier / Gabelle, Audrey / Ceccaldi, Mathieu / Krolak‐Salmon, Pierre / Béjot, Yannick / Godefroy, Olivier et al. | 2021
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Midlife vascular risk factors and risk of incident dementia: Longitudinal cohort and Mendelian randomization analyses in the UK BiobankMalik, Rainer / Georgakis, Marios K. / Neitzel, Julia / Rannikmäe, Kristiina / Ewers, Michael / Seshadri, Sudha / Sudlow, Cathie L.M. / Dichgans, Martin et al. | 2021
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Head injury and 25‐year risk of dementiaSchneider, Andrea L. C. / Selvin, Elizabeth / Latour, Lawrence / Turtzo, L. Christine / Coresh, Josef / Mosley, Thomas / Ling, Geoffrey / Gottesman, Rebecca F. et al. | 2021
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Ophthalmic conditions associated with dementia risk: The Cardiovascular Health StudyHwang, Phillip H. / Longstreth, Will T. Jr. / Thielke, Stephen M. / Francis, Courtney E. / Carone, Marco / Kuller, Lewis H. / Fitzpatrick, Annette L. et al. | 2021
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Replication study of plasma proteins relating to Alzheimer's pathologyShi, Liu / Winchester, Laura M. / Westwood, Sarah / Baird, Alison L. / Anand, Sneha N. / Buckley, Noel J / Hye, Abdul / Ashton, Nicholas J. / Bos, Isabelle / Vos, Stephanie J. B. et al. | 2021
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Extrapyramidal signs and Alzheimer's disease prognosis in a multiethnic, community‐based sample of demented eldersKociolek, Anton J. / Fernandez, Kayri K. / Jin, Zhezhen / Cosentino, Stephanie / Zhu, Carolyn W. / Gu, Yian / Stern, Yaakov et al. | 2021
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Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expressionSaito, Erin R. / Miller, Justin B. / Harari, Oscar / Cruchaga, Carlos / Mihindukulasuriya, Kathie A. / Kauwe, John S. K. / Bikman, Benjamin T. et al. | 2021
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Systematic in silico analysis of clinically tested drugs for reducing amyloid‐beta plaque accumulation in Alzheimer's diseaseMadrasi, Kumpal / Das, Raibatak / Mohmmadabdul, Hafiz / Lin, Lin / Hyman, Bradley T. / Lauffenburger, Douglas A. / Albers, Mark W. / Rissman, Robert A. / Burke, John M. / Apgar, Joshua F. et al. | 2021
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AMYQ: An index to standardize quantitative amyloid load across PET tracersPegueroles, Jordi / Montal, Victor / Bejanin, Alexandre / Vilaplana, Eduard / Aranha, Mateus / Santos‐Santos, Miguel Angel / Alcolea, Daniel / Carrió, Ignasi / Camacho, Valle / Blesa, Rafael et al. | 2021
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Whole‐genome sequencing reveals new Alzheimer's disease–associated rare variants in loci related to synaptic function and neuronal developmentProkopenko, Dmitry / Morgan, Sarah L. / Mullin, Kristina / Hofmann, Oliver / Chapman, Brad / Kirchner, Rory / Amberkar, Sandeep / Wohlers, Inken / Lange, Christoph / Hide, Winston et al. | 2021
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Measures of resting state EEG rhythms for clinical trials in Alzheimer's disease: Recommendations of an expert panelBabiloni, Claudio / Arakaki, Xianghong / Azami, Hamed / Bennys, Karim / Blinowska, Katarzyna / Bonanni, Laura / Bujan, Ana / Carrillo, Maria C. / Cichocki, Andrzej / de Frutos‐Lucas, Jaisalmer et al. | 2021
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Visualization of neurofibrillary tangle maturity in Alzheimer's disease: A clinicopathologic perspective for biomarker researchMoloney, Christina M. / Lowe, Val J. / Murray, Melissa E. et al. | 2021
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The Alzheimer's Association international guidelines for handling of cerebrospinal fluid for routine clinical measurements of amyloid β and tauHansson, Oskar / Batrla, Richard / Brix, Britta / Carrillo, Maria C. / Corradini, Veronika / Edelmayer, Rebecca M. / Esquivel, Rianne N. / Hall, Christina / Lawson, John / Bastard, Nathalie Le et al. | 2021
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Scientific meetings highlight collaboration and discovery| 2021
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Alzheimer's Disease Interventions: Implications of therapeutic promises amidst questions and doubts about clinically meaningful outcomes| 2021
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Quantifying progression in primary progressive aphasia with structural neuroimagingLombardi, Jolina / Mayer, Benjamin / Semler, Elisa / Anderl‐Straub, Sarah / Uttner, Ingo / Kassubek, Jan / Diehl‐Schmid, Janine / Danek, Adrian / Levin, Johannes / Fassbender, Klaus et al. | 2021
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Early prevention of cognitive impairment in the community population: The Beijing Aging Brain Rejuvenation InitiativeYang, Caishui / Li, Xin / Zhang, Junying / Chen, Yaojing / Li, He / Wei, Dongfeng / Lu, Peng / Liang, Ying / Liu, Zhen / Shu, Ni et al. | 2021
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Associations of loneliness with risk of Alzheimer's disease dementia in the Framingham Heart StudyAkhter‐Khan, Samia C. / Tao, Qiushan / Ang, Ting Fang Alvin / Itchapurapu, Indira Swetha / Alosco, Michael L. / Mez, Jesse / Piers, Ryan J. / Steffens, David C. / Au, Rhoda / Qiu, Wei Qiao et al. | 2021
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TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levelsHong, Shengjun / Dobricic, Valerija / Ohlei, Olena / Bos, Isabelle / Vos, Stephanie J. B. / Prokopenko, Dmitry / Tijms, Betty M. / Andreasson, Ulf / Blennow, Kaj / Vandenberghe, Rik et al. | 2021
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Functional decline in the aphasic variant of Alzheimer's diseaseMoeller, Stacey / Sridhar, Jaiashre / Martersteck, Adam / Coventry, Christina / Kuang, Alan / Zhang, Hui / Weintraub, Sandra / Mesulam, M.‐Marsel / Rogalski, Emily et al. | 2021
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Plasma P‐tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular diseaseChong, Joyce R. / Ashton, Nicholas J. / Karikari, Thomas K. / Tanaka, Tomotaka / Saridin, Francis N. / Reilhac, Anthonin / Robins, Edward G. / Nai, Ying‐Hwey / Vrooman, Henri / Hilal, Saima et al. | 2021
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Plasma amyloid β levels are driven by genetic variants near APOE, BACE1, APP, PSEN2: A genome‐wide association study in over 12,000 non‐demented participantsDamotte, Vincent / van der Lee, Sven J. / Chouraki, Vincent / Grenier‐Boley, Benjamin / Simino, Jeannette / Adams, Hieab / Tosto, Giuseppe / White, Charles / Terzikhan, Natalie / Cruchaga, Carlos et al. | 2021
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Characterization of dementia with Lewy bodies (DLB) and mild cognitive impairment using the Lewy body dementia module (LBD‐MOD)Galvin, James E. / Chrisphonte, Stephanie / Cohen, Iris / Greenfield, Keri K. / Kleiman, Michael J. / Moore, Claudia / Riccio, Mary Lou / Rosenfeld, Amie / Shkolnik, Niurka / Walker, Marcia et al. | 2021
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Agitation in Alzheimer's disease: Novel outcome measures reflecting the International Psychogeriatric Association (IPA) agitation criteriaDe Mauleon, Adelaide / Ismail, Zahinoor / Rosenberg, Paul / Miller, David / Cantet, Christelle / O'Gorman, Cedric / Vellas, Bruno / Lyketsos, Constantine / Soto, Maria et al. | 2021
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Validation and demonstration of a new comprehensive model of Alzheimer's disease progressionStern, Yaakov / Stallard, Eric / Kinosian, Bruce / Zhu, Carolyn / Cosentino, Stephanie / Jin, Zhezhen / Gu, Yian et al. | 2021
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Validity of the 2014 traumatic encephalopathy syndrome criteria for CTE pathologyMez, Jesse / Alosco, Michael L. / Daneshvar, Daniel H. / Saltiel, Nicole / Baucom, Zachary / Abdolmohammadi, Bobak / Uretsky, Madeline / Nicks, Raymond / Martin, Brett M. / Palmisano, Joseph N. et al. | 2021
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Hearing impairment and missing cognitive test scores in a population‐based study of older adults: The Atherosclerosis Risk in Communities neurocognitive studyDeal, Jennifer A. / Gross, Alden L. / Sharrett, A. Richey / Abraham, Alison G. / Coresh, Josef / Carlson, Michelle / Griswold, Michael / Mosley, Thomas / Power, Melinda C. / Ramulu, Pradeep et al. | 2021
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Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL‐1β drives amplified responses in primed astrocytes and neuronal network dysfunctionLopez‐Rodriguez, Ana Belen / Hennessy, Edel / Murray, Carol L. / Nazmi, Arshed / Delaney, Hugh J. / Healy, Dáire / Fagan, Steven G. / Rooney, Michael / Stewart, Erika / Lewis, Anouchka et al. | 2021
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Elevated plasma neurofilament light predicts a faster rate of cognitive decline over 5 years in participants with objectively‐defined subtle cognitive decline and MCIBangen, Katherine J. / Thomas, Kelsey R. / Weigand, Alexandra J. / Edmonds, Emily C. / Clark, Alexandra L. / Solders, Seraphina / Delano‐Wood, Lisa / Galasko, Douglas R. / Bondi, Mark W. / for the Alzheimer's Disease Neuroimaging Initiative et al. | 2021
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The impact of diabetes on cognitive impairment and its progression to dementiaDove, Abigail / Shang, Ying / Xu, Weili / Grande, Giulia / Laukka, Erika J. / Fratiglioni, Laura / Marseglia, Anna et al. | 2021
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Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by TOMM40–APOE variants in menKulminski, Alexander M. / Philipp, Ian / Loika, Yury / He, Liang / Culminskaya, Irina et al. | 2021
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Relationships among tau burden, atrophy, age, and naming in the aphasic variant of Alzheimer's diseaseMartersteck, Adam / Sridhar, Jaiashre / Coventry, Christina / Weintraub, Sandra / Mesulam, M.‐Marsel / Rogalski, Emily et al. | 2021
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Body mass index in early adulthood and dementia in late life: Findings from a pooled cohortZeki Al Hazzouri, Adina / Vittinghoff, Eric / Hoang, Tina / Golden, Sherita H. / Fitzpatrick, Annette L. / Zhang, Adina / Grasset, Leslie / Yaffe, Kristine et al. | 2021
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Recruitment of a multi‐site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trialShadyab, Aladdin H. / LaCroix, Andrea Z. / Feldman, Howard H. / van Dyck, Christopher H. / Okonkwo, Ozioma C. / Tam, Steven P. / Fairchild, J. Kaci / Welsh‐Bohmer, Kathleen A. / Matthews, Genevieve / Bennett, Daniel et al. | 2021
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Dementia is an age‐independent risk factor for severity and death in COVID‐19 inpatientsTahira, Ana C. / Verjovski‐Almeida, Sergio / Ferreira, Sergio T. et al. | 2021
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Health utility in preclinical and prodromal Alzheimer's disease for establishing the value of new disease‐modifying treatments—EQ‐5D data from the Swedish BioFINDER studyGustavsson, Anders / Raket, Lars Lau / Lilja, Mathias / Rutten‐Jacobs, Loes / Fues Wahl, Hanna / Bagijn, Marloes / Stomrud, Erik / Hansson, Oskar / Palmqvist, Sebastian et al. | 2021
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What can 7T sodium MRI tell us about cellular energy depletion and neurotransmission in Alzheimer's disease?Haeger, Alexa / Bottlaender, Michel / Lagarde, Julien / Porciuncula Baptista, Renata / Rabrait‐Lerman, Cécile / Luecken, Volker / Schulz, Jörg B. / Vignaud, Alexandre / Sarazin, Marie / Reetz, Kathrin et al. | 2021
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Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring announces new editor‐in‐chief for open access, peer reviewed journal| 2021
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Late‐onset schizophrenia and the competing risks of dementia and death: A national cohort studyLevine, Stephen Z / Weinstein, Galit / Rotstein, Anat / Goldberg, Yair / Reichenberg, Abraham / Sandin, Sven / Kodesh, Arad et al. | 2021
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Policy recommendations from the perspective of health professionals who work with people with dementia in public tertiary hospitals in ChinaZhao, Wenhong / Moyle, Wendy / Wu, Min‐Lin (Winnie) / Petsky, Helen et al. | 2021
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Adapted Tango to improve blood inflammatory markers in middle‐aged African‐American female caregivers of persons with Alzheimer's disease: A clinical trialWharton, Whitney / Jeong, Leanne / Ni, Liang / Bay, Allison A / Shin, Ryan / McCullough, Lauren / Silverstein, Hayley / Hart, Ariel R / Swieboda, Dominika / Hu, William T et al. | 2021
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Designing future nutrition clinical trials for dementia preventionSchneider, Lon S et al. | 2021
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Development and validation of the Yonsei Lifestyle Profile‐Satisfaction (YLP‐S) using the Rasch measurement modelPark, Kang‐Hyun / Park, Ji‐Hyuk / Hong, Ickpyo et al. | 2021
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Association of a MIND diet with the risk of dementia and brain structure in a French older populationThomas, Aline / Féart, Catherine / Helmer, Catherine / Catheline, Gwenaelle / Samieri, Cécilia et al. | 2021
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Modifications in response to the COVID‐19 pandemic in a multimodal intervention trial to prevent cognitive impairment in older women with cardiovascular diseaseHalloway, Shannon / Arvanitakis, Zoe / Wilbur, JoEllen / Schoeny, Michael E / Barnes, Lisa L / Pressler, Susan J / Gamboa, Charlene / Knudson, Krista / Borgia, Jeffrey A / Volgman, Annabelle Santos et al. | 2021
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Greater COVID‐19 impact for underrepresented racial and ethnic minority groups: A survey study on the Wisconsin Alzheimer’s Disease Research Center participantsMa, Yue / Spalitta, Alice / Wahoske, Michelle L / Blazel, Hanna / Chappell, Richard J / Chin, Nathaniel A / Johnson, Sterling C / Asthana, Sanjay / Gleason, Carey E / Carlsson, Cynthia M et al. | 2021
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The gut microbiome and cognitive function in midlife: The CARDIA studyMeyer, Katie A et al. | 2021
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Association between sleep, depressive symptoms, and pain with physical activity and physical functioning in the oldest old: CAIDE 85+ studyKekkonen, Eija / Hall, Anette / Kulmala, Jenni / Lisko, Inna / Ngandu, Tiia / Barbera, Mariagnese / Hallikainen, Merja / Soininen, Hilkka / Kivipelto, Miia / Solomon, Alina et al. | 2021
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Traumatic brain injury accelerates Parkinson’s disease onset without altering Parkinson’s neuropathologySpiegel, Jonathan / Sone, Je Yeong / Butler, Tracy / Pirraglia, Elizabeth / de Leon, Mony J et al. | 2021
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Influence of lifespan cognitive reserve indicator on cognitive trajectories in different domains: role of brain pathologiesLi, Xuerui / Song, Ruixue / Xu, Hui / Yang, Wenzhe / Qi, Xiuying / Kivipelto, Miia / Bennett, David A / Xu, Weili et al. | 2021
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Community paramedic‐delivered care transitions intervention reduces emergency department revisits among cognitively impaired patientsShah, Manish N / Green, Rebecca K / Jacobsohn, Gwen C / Jones, Courtney MC / Caprio, Thomas V / Cochran, Amy L / Cushman, Jeremy T / DuGoff, Eva / Lohmeier, Michael / Kind, Amy J et al. | 2021
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Fish intake and MRI burden of cerebrovascular disease in older adultsThomas, Aline / Crivello, Fabrice / Mazoyer, Bernard / Debette, Stéphanie / Tzourio, Christophe / Samieri, Cécilia et al. | 2021
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Association of dual impairment in physical performance and cognition with cognitive change over two years in older adultsPeng, Tao‐Chun / Chen, Yen‐Ching / Chen, Ta‐Fu / Chiou, Jeng‐Min / Chen, Jen‐Hau et al. | 2021
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Associations between social networks and cognitive declines in later life in longitudinal aging studies: A systematic review and meta‐analysisZhang, Yun / Clouston, Sean AP et al. | 2021
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Causal mediation analysis with longitudinal data: Relationships among sleep quality, diabetes, and subjective memory in older adultsPark, Sang‐Mi / Lee, Chang Dae et al. | 2021
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Cognitive decline related to substance consumption in a Colombian kindred with familial Alzheimer's disease: A retrospective cohort studyRamos‐Perez, Claudia Patricia / Villalba, Arvey Camilo / Garcia, Jenny / Lanata, Serggio / Lopez, Hugo Elias / Aguirre‐Acevedo, Daniel C / Lopera, Francisco et al. | 2021
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Compromised immunity rather than specific microbe may increase vulnerability to Alzheimer’s disease, and vaccines with beneficial off‐target effects may support immunity and prevent ADUkraintseva, Svetlana / Yashkin, Arseniy Pavlovich / Akushevich, Igor / Arbeev, Konstantin / Duan, Matt / Tropsha, Alex / Stallard, Eric / Yashin, Anatoliy et al. | 2021
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Trajectories of daytime sleepiness and sleep duration before diagnosis of dementia: A 14‐year follow‐up studyCavaillès, Clémence / Carriere, Isabelle / Wagner, Maude / Berr, Claudine / Dauvilliers, Yves / Jaussent, Isabelle et al. | 2021
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Anticholinergic burden and cognitive performance: Cross‐sectional results from the ELSA–Brasil studyMedeiros dos Santos, Adriana Nancy / Brunoni, Andre R / Goulart, Alessandra C / Viana, Maria Carmen / Benseñor, Isabela / Lotufo, Paulo / Suemoto, Claudia Kimie et al. | 2021
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Regression based machine learning model for dementia diagnosis in a community settingSalem, Fatima Abu / Chaaya, Monique / Ghannam, Hiyam / Al Feel, Roaa E / El Asmar, Khalil et al. | 2021
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The association of the ANU‐ADRI Alzheimer risk index score with cognition in the FINGER studyHall, Anette / Barbera, Mariagnese / Stephen, Ruth / Lehtisalo, Jenni / Ngandu, Tiia / Anstey, Kaarin J / Kivipelto, Miia / Solomon, Alina et al. | 2021
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The impact of the COVID‐19 pandemic on cognitive healthBrooker, Helen / Hayman, Vincent / Aarsland, Dag / Creese, Byron / Ballard, Clive / Corbett, Anne et al. | 2021
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Multidomain interventions for dementia risk reduction: Can we detect a change in the signal?Lussier, Isabelle / Guillemont, Juliette / Bacon, Simon L / Boivin, Michel / Ferland, Guylaine / Lavoie, Kim / Paré, Guy / Belleville, Sylvie et al. | 2021
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Mixed methods used in the refinement of an Alzheimer’s study registry to optimize recruitment of Latinx and Black individualsAggarwal, Raj / Stowell, Carter / Plant, Aaron / Creech, Deborah Neffa / George, Sheba / Williams, Emily / Fiore, Nora / Langbaum, Jessica B et al. | 2021
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The effect of missing cognitive data on the detection of bias due to hearing impairment in cognitive testingNichols, Emma / Deal, Jennifer A / Swenor, Bonnielin K / Abraham, Alison / Griswold, Michael E / Lin, Frank R / Mosley, Thomas H Jr. / Reed, Nicholas S / Sharrett, Richey / Gross, Alden L et al. | 2021
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Can engagement in socially and cognitively stimulating leisure activities compensate for other dementia risk factors? A prospective cohort studyDuffner, Lukas / Deckers, Kay / Cadar, Dorina / Steptoe, Andrew / de Vugt, Marjolein / Koehler, Sebastian et al. | 2021
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Tailoring recruitment message content to reach diverse communities for AD research participationEdwards, Dorothy Farrar / Dykema, Jennifer et al. | 2021
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Engagement with a preventive eHealth intervention in older adults (the HATICE trial): Predictive factors and associations with dementia and cardiovascular riskColey, Nicola / Andre, Laurine / Hoevenaar‐Blom, Marieke P / Ngandu, Tiia / Beishuizen, Cathrien / Barbera, Mariagnese / van Wanrooij, Lennard / Kivipelto, Miia / Soininen, Hilkka / Brayne, Carol et al. | 2021
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Ketones and improved cognition in MCI: Links to ApoE and white matter energeticsCunnane, Stephen / Roy, Maggie / Rheault, François / Fortier, Melanie / Descoteaux, Maxime / Castellano, Christian‐Alexandre / St. Pierre, Valerie / Bocti, Christian / Fulop, Tamas et al. | 2021
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Entorhinal thickness: A marker of DHA supplementation efficacy?Yassine, Hussein N / Solomon, Victoria A / He, Xulei / Cordova, Isabella / Kono, Naoko / Mack, Wendy J / Chui, Helena C / Schneider, Lon S / Harrington, Michael G / Braskie, Meredith N et al. | 2021
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Randomized trial of n‐3 PUFA for cerebral white matter hyperintensities, medial temporal lobe atrophy and white matter integrity in older non‐demented adults: Per‐protocol and ApoE stratified resultsBowman, Gene L / Murchison, Charles F / Silbert, Lisa C / Dodge, Hiroko H / Hagen, Kirsten / Lahna, David / Harris, William S / Kaye, Jeffrey A / Quinn, Joseph F / Shinto, Lynne et al. | 2021
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One in five community‐dwelling older adults will develop Alzheimer's dementia in five yearsFord, Christopher N / Rajan, Kumar B / Bennett, David A et al. | 2021
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Statin therapies reduce risk of Alzheimer’s disease and dementia with increased protective therapeutic effect with increasing ageTorrandell‐Haro, Georgina / Branigan, Gregory L / Vitali, Francesca / Brinton, Roberta Diaz et al. | 2021
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Iron intake, brain iron, and Alzheimer’s disease among community‐dwelling older adultsAgarwal, Puja / Ayton, Scott / Wang, Yamin / Agrawal, Sonal / Bennett, David A / Barnes, Lisa L / Leurgans, Sue E / Bush, Ashley I / Schneider, Julie A et al. | 2021
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MIND diet and risk of dementia in a population‐based cohortde Crom, Tosca / Ikram, M Arfan / Voortman, Trudy et al. | 2021
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Imagining the preventive city: How can urban environments support dementia prevention? A qualitative studyRoehr, Susanne / Rodriguez, Francisca S / Siemensmeyer, Rosa / Mueller, Felix / Romero‐Ortuno, Roman / Riedel‐Heller, Steffi G et al. | 2021
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Prevalence of dementia among elderly in Latin America and the Caribbean: A systematic review and meta‐analysisRibeiro, Fabiana / Santos, Ana Carolina Teixeira / Leist, Anja et al. | 2021
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Napping characteristics and cognitive function in older adultsLeng, Yue / Hagen, Erika W / Ravelo, Laurel A / Peppard, Paul E / Yaffe, Kristine et al. | 2021
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Effects of COVID‐19 on cognition of older African AmericansKavcic, Voyko / Podlesek, Anja / DiCerbo, Loraine M / Hanna, Sophie / Shair, Sarah / Giordani, Bruno et al. | 2021
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Cognition and elevated blood pressure in community‐dwelling older adults with subjective cognitive decline: A cross‐sectional exploratory studySilva, Narlon Cassio Boa Sorte / Gill, Dawn P / Owen, Adrian M / Petrella, Robert J et al. | 2021
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Factors associated with early and late onset Alzheimer disease in Down syndromeLai, Florence / Wang, Cassandra / Mercaldo, Nathaniel / Rosas, H Diana et al. | 2021
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Towards a brain health diplomacy toolkit: Supporting tomorrow's brain health leadersDawson, Walter D / Eyre, Harris A et al. | 2021
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Healthcare costs incurred by patients before entering GERAS‐US, a prospective, observational study of early Alzheimer’s disease: Impact of disease severity and amyloid statusChandler, Julie / Zimmer, Jennifer A / Kubisiak, Emily / Kubisiak, Joanna et al. | 2021
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Why would Canada have the longest wait times for an Alzheimer’s treatment among the G7 countries? A policy analysisMattke, Soeren / Wang, Mo et al. | 2021
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A study on the research trends of effectiveness of telehealth for the elderly through bibliographic analysisPark, SunHa et al. | 2021
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The screening and enrollment of underrepresented ethnoracial and educational populations in the Alzheimer's Disease Neuroimaging InitiativeAshford, Miriam T / Miller, Garrett / Raman, Rema / Donohue, Michael C / Okonkwo, Ozioma C / Mindt, Monica Rivera / Nosheny, Rachel L / Petersen, Ronald C / Aisen, Paul S / Weiner, Mike W et al. | 2021
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Physical activity and amyloid beta in middle‐aged and older adults: A systematic review and meta‐analysisRodriguez‐Ayllon, Maria / Arroyo‐Avila, Cristina / Alvarez‐Ortega, Miriam / Molina‐Garcia, Pablo / Solis‐Urra, Patricio / Molina‐Hidalgo, Cristina / Erickson, Kirk I / Esteban‐Cornejo, Irene et al. | 2021
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Association of neighborhood‐level socioeconomic advantage with cognition and dementia risk factors in an Australian cohortCavuoto, Marina G / Rowsthorn, Ella / Lavale, Alexandra / Yassi, Nawaf / Maruff, Paul T / Buckley, Rachel F / Lim, Yen Ying / Pase, Matthew P et al. | 2021
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Life activity patterns and mild cognitive impairment in older adultsWu, Chao‐Yi / Gothard, Sarah / Mattek, Nora / Wright, Kirsten M / Kaye, Jeffrey A / Dodge, Hiroko H / Beattie, Zachary et al. | 2021
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Conversational artificial intelligence and affective social robot for monitoring health and well‐being of people with dementiaWairagkar, Maitreyee / De Lima, Maria Raposo / Harrison, Matthew / Batey, Philippa / Daniels, Sarah / Barnaghi, Payam / Sharp, David J / Vaidyanathan, Ravi et al. | 2021
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Validation of dementia diagnostics toolbox using interactive iPad technologyChandra, Jay / Muthupalaniappan, Siva / Shang, Zisheng / Bose, Soham / Deng, Richard / Pecyna, Eryk / Chen, Alexander / Lin, Raymond / Butts, Dignity / Capo‐Battaglia, Athena et al. | 2021
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Comparison of remote and in‐person digital speech‐based measures of cognitionStegmann, Gabriela M / Hahn, Shira / Liss, Julie / Berisha, Visar / Mueller, Kimberly D et al. | 2021
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Deletion of the SPAG9 gene cause autosomal‐recessive intellectual disabilityAcosta‐Baena, Natalia / Tejada‐Moreno, Johanna A. / García, Alejandro Mejía / Caro, María Antonieta / Bedoya‐Berrío, Gabriel et al. | 2021
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Therapeutic investigation of alpha napthoflavone in the intracerebroventricular injection of L‐cysteine induced vascular dementia in ratsRishitha, Narahari / Muthuraman, Arunachalam et al. | 2021
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Praxis deficits in patients with Parkinson’s diseaseRounis, Elisabeth et al. | 2021
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Effect of insulin resistance on the association between cardiorespiratory fitness and cognition in adults at risk for Alzheimer's diseaseMcIntyre, Clayton Connor / Okonkwo, Ozioma C. / Gaitán, Julian M. / Bendlin, Barbara B / Edmunds, Kyle J et al. | 2021
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Assessment of Vision Function and Cognitive Dysfunction in Older Adults through Questionnaire SurveysRashik, Mohammad / Mozdbar, Sima / Aryal, Subhash / Johnson, Leigh Ann / O'Bryant, Sid et al. | 2021
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Electrophysiological Examination of Executive Functioning in Lean and Obese Younger AdultsLarsen, Brittany A / Klinedinst, Brandon S / Grundy, John / Willette, Auriel A et al. | 2021
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Deep Residual Inception Encoded‐Decoder Neural Network for amyloid PET harmonizationShah, Jay / Ghisays, Valentina / Luo, Ji / Chen, Yinghua / Lee, Wendy / Li, Baoxin / Benzinger, Tammie L.S. / Reiman, Eric M. / Chen, Kewei / Su, Yi et al. | 2021
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Investigating the impact of scatter correction on CentiloidLi, Shenpeng / O'Keefe, Graeme / Gillman, Ashley / Burnham, Samantha C / Masters, Colin L / Williams, Robert / Rowe, Christopher C / Fripp, Jurgen / Bourgeat, Pierrick / Villemagne, Victor L et al. | 2021
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Do polygenic scores of cerebral small vessel disease MRI markers predict white matter lesions?de Silva, Eric / Sudre, Carole H / Barnes, Jo / Scelsi, Marzia Antonella / Altmann, Andre et al. | 2021
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Neural somatosensory dysfunction is masked by variable executive declines across the Alzheimer’s disease spectrumWiesman, Alex I / Mundorf, Victoria M / Wolfson, Sara L / Johnson, Craig M / May, Pamela E / Murman, Daniel L / Wilson, Tony W et al. | 2021
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Semi‐quantitative [11C]PiB and [15O]H2O PET measures of cerebrospinal fluid dynamics discriminate amyloid load but not cognitive statusMinhas, Davneet S / Laymon, Charles M / Lopresti, Brian J / Cohen, Ann D / Tudorascu, Dana L / Mason, Neale S / Lopez, Oscar L. / Villemagne, Victor L / Aizenstein, Howard J / Mathis, Chester A et al. | 2021
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Baseline structural MRI and plasma biomarkers predict longitudinal structural atrophy and cognitive decline in early ADXie, Long / Das, Sandhitsu R. / Wisse, Laura / Ittyerah, Ranjit / de Flores, Robin / Yushkevich, Paul A. / Wolk, David A. et al. | 2021
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Neuroimaging and clinical characteristics of cognitive migration in community‐dwelling older adultsDuran, Tugce / Bateman, James R. / Williams, Benjamin J. / Okonmah‐Obazee, Stephanie / Craft, Suzanne / Lockhart, Samuel N. et al. | 2021
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rPOP: Robust PET‐only processing and quantification of community‐acquired amyloid‐PET from the IDEAS StudyIaccarino, Leonardo / La Joie, Renaud / Koeppe, Robert / Siegel, Barry A / Hillner, Bruce E / Gatsonis, Constantine / Whitmer, Rachel A. / Carrillo, Maria C. / Apgar, Charles / Camacho, Monica R et al. | 2021
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Modified Mediterranean ketogenic diet resolves default mode network connectivity differences between adults with normal and impaired cognitionKawas, Mohammad I / Lockhart, Samuel N. / Kim, Jeongchul / Neth, Bryan J. / Barcus, Richard A. / Hughes, Tim M. / Solingapuram Sai, Kiran K / Craft, Suzanne / Whitlow, Christopher T. et al. | 2021
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Prodromal markers of neurodegenerative disease: Insights from the UK Biobank datasetStreet, Duncan / Whiteside, David / Rittman, Timothy / Rowe, James B. et al. | 2021
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Fully automated immunoassays for measuring beta‐amyloid peptide (1‐42) and total tau in cerebral spinal fluidKozo, Daniel R et al. | 2021
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Prediction of Alzheimer disease using plasma RNA sequences from dementia genesIbanez, Laura / Bergmann, Kristy / Eteleeb, Abdallah / Wang, Fengxian / Norton, Joanne / Gentsch, Jen / Harari, Oscar / Cruchaga, Carlos et al. | 2021
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Motor proficiency composite scores as a novel biomarker for Alzheimer's diseaseKoppelmans, Vincent / Ruitenberg, Marit F.L. / Van der Geest, Jos / Duff, Kevin M. et al. | 2021
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Longitudinal tau accumulation in cognitively normal older adults is associated with baseline age, pathology, and activationAdams, Jenna N. / Harrison, Theresa M. / Maass, Anne / Baker, Suzanne L. / Jagust, William J. et al. | 2021
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Clinical and biological heterogeneity in autosomal dominant Alzheimer's diseaseQuiroz, Yakeel T. / Aguilar, Laura Ramirez / Giraldo‐Chica, Margarita / Aguillon, David / Baena, Ana Y. / Bocanegra, Yamile / Vila‐Castelar, Clara / Fox‐Fuller, Joshua T. / Pluim, Celina F. / Aduen, Paula et al. | 2021
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Analysis of brain structural connectivity networks and white matter integrity in patients with mild cognitive impairmentBergamino, Maurizio / Walsh, Ryan R. / Stokes, Ashley M. et al. | 2021
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Classification of AD/MCI/HC based on amyloid‐PET using Random Forest EnsembleBao, Yiwen / Chiu, Patrick Ka‐Chun / Shea, Yat Fung / Kwan, Joseph S.K. / Chan, Hon Wai Felix / Mak, Henry et al. | 2021
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Cerebrospinal fluid and saliva lactoferrin as a diagnostic biomarker for Alzheimer’s disease in a mixed memory clinic populationGleerup, Helena Sophia / Jensen, Camilla Steen / Høgh, Peter / Hasselbalch, Steen Gregers / Simonsen, Anja Hviid et al. | 2021
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Multimodal evaluation of the melanopsin retinal ganglion cells system in relation to circadian rhythms in Alzheimer’s disease and agingLa Morgia, Chiara / Mitolo, Micaela / Santoro, Aurelia / Romagnoli, Martina / Maserati, Michelangelo Stanzani / Evangelisti, Stefania / De Matteis, Maddalena / Palombo, Flavia / Bacalini, Maria Giulia / Capellari, Sabina et al. | 2021
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Poor sleep is associated with smaller hippocampal subfields in cognitively normal elderly individualsAlperin, Noam et al. | 2021
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Optimization of biosensor cell lines for the detection of tau seeding competency in human CSFLathuiliere, Aurelien / Jo, Youhwa / Fan, Zhanyun / Hyman, Bradley T. et al. | 2021
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Tau and synaptic biomarkers but not amyloid‐β are associated with cerebral perfusion in the Alzheimer’s disease spectrumAhmadi, Khazar / Pereira, Joana B. / Berron, David / Vogel, Jacob W. / Ingala, Silvia / Strandberg, Olof / Janelidze, Shorena / Barkhof, Frederik / Knutsson, Linda / van Westen, Danielle et al. | 2021
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Classified biomarker panel with tau microtubule binding regions identifies pathophysiological changes in Alzheimer’s disease continuumHorie, Kanta / Barthelemy, Nicolas R. / Sato, Chihiro / Li, Yan / McDade, Eric / Bateman, Randall J. et al. | 2021
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Older adults with Alzheimer’s disease exhibit an altered relationship between plasma sTREM2 and inflammatory markersWeber, Grace E. / Khrestian, Maria / Tuason, Elizabeth D. / Shao, Yvonne / Pillai, Jagan A. / Rao, Stephen M. / Feng, Hao / DeSilva, Tara M. / Stauffer, Shaun / Leverenz, James B. et al. | 2021
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Amyloid‐tau‐neurodegeneration (ATN) profiles and influence of age‐of‐onset on cognitive trajectories in a Southeast Asian cohort: SYNC projectVipin, Ashwati / Koh, Chen Ling / Wong, Benjamin / Zailan, Fatin Zahra / Tan, Yi Jayne / Soo, See Ann / Satish, Vaynii / Kumar, Dilip / Wang, Brian Zhiyang / Ng, Adeline Su Lyn et al. | 2021
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Multimodal brain imaging demonstrates that both amyloid burden and glucose metabolism predict the severity of cognitive impairment in patients with Alzheimer’s diseaseAtay, Lutfiye Ozlem / Akdemir, Umit Ozgur / Yetim, Ezgi / Balci, Erdem / Arsava, Ethem Murat / Topcuoglu, Mehmet Akif / Saka, Esen et al. | 2021
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The auditory mismatch negativity reflects accelerated aging in adults with Down’s syndromeAvancini, Chiara / Cambridge Intellectual and Developmental Disabilities Research Group et al. | 2021
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Why don’t Alzheimer’s disease patients know that they forget?Razafimahatratra, Solofo / Guieysse, Thomas / Medani, Takfarinas / Lejeune, François‐Xavier / Houot, Marion / George, Nathalie / La Corte, Valentina / Klarsfeld, André / Dreyfus, Gérard / Pantazis, Dimitrios et al. | 2021
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Saliva biomarkers for Alzheimer’s disease risk in a rat model of low and high intrinsic exercise capacityAlmarghalani, Daniyah / Hardy, Ana Maria Gregio / Hasan, Syed Abdul‐Moiz / Shah, Zahoor A. / Koch, Lauren Gerard et al. | 2021
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Falls predict cognitive statusGray, Michelle / Paulson, S. / Gills, J.L. / Glenn, J.M. / Madero, E.N. / Myers, J. / Campitelli, A. / Jones, M. / Vincenzo, J. / Walter, C. et al. | 2021
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SavaDx, a novel plasma biomarker to detect Alzheimer’s disease, confirms mechanism of action of simufilamWang, Hoau‐Yan / Pei, Zhe / Xu, Qiang / Brunelle, Lynn A / Burns, Lindsay H. / Thornton, George Ben et al. | 2021
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Investigating white matter connectomes in amnestic and non‐amnestic Alzheimer's disease clinical variantsBharne, Pandurang R. / Kinney, Nikolas G. / Da Re, Fulvio / Spotorno, Nicola / Olm, Christopher A. / Cook, Philip / Irwin, David J. / McMillan, Corey T. / Grossman, Murray / Phillips, Jeffrey S. et al. | 2021
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Cerebrospinal fluid and brain PET measures of synaptic density glycoprotein 2A: Biomarkers of synaptic density in Alzheimer’s diseaseMecca, Adam P. / Ashton, Nicholas J. / Chen, Ming‐Kai / O'Dell, Ryan S. / Naganawa, Mika / Toyonaga, Takuya / Zhao, Wenzhen / Nabulsi, Nabeel B. / Brinkmalm, Ann / Kvartsberg, Hlin et al. | 2021
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Relationship between resting state alpha electroencephalographic rhythms and aging in cognitively unimpaired seniors and patients with mild cognitive impairment due to Alzheimer’s disease and amnestic mild cognitive impairmentDel Percio, Claudio / Lizio, Roberta / Noce, Giuseppe / Lopez, Susanna / Soricelli, Andrea / Ferri, Raffaele / Güntekin, Bahar / Yener, Gorsev / Marizzoni, Moira / Frisoni, Giovanni B et al. | 2021
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Decrease of event related theta power is more profound in patients with Parkinson's disease dementia in comparison to Alzheimer's disease dementiaYıldırım, Ebru / Gündüz, Duygu Hünerli / Hanoğlu, Lutfu / Yener, Gorsev / Güntekin, Bahar et al. | 2021
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CSF amyloid, tau, and neurodegeneration biomarkers are associated with longitudinal cognitive decline in preclinical ADCody, Karly Alex / Betthauser, Tobey J. / Hulle, Carol A. / Koscik, Rebecca L. / Jonaitis, Erin M. / Clark, Lindsay R. / Chin, Nathaniel A. / Okonkwo, Ozioma C. / Bendlin, Barbara B. / Asthana, Sanjay et al. | 2021
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Discrepancy between plasma pTau181 and tau‐PET statusesTissot, Cécile / Kunach, Peter / Therriault, Joseph / Lussier, Firoza Z. / Benedet, Andréa Lessa / Chamoun, Mira / Pascoal, Tharick A. / Servaes, Stijn / Bezgin, Gleb / Arias, Jaime Fernandez et al. | 2021
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Quantitative assessment of cortical excitability in Alzheimer’s dementia and its association with clinical symptoms: A systematic review and meta‐analysesJoseph, Shaylyn / Patterson, Rachel A. / Wang, Wei / Blumberger, Daniel M. / Rajji, Tarek K. / Kumar, Sanjeev et al. | 2021
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Pre‐pivotal clinical study of β‐amyloid in the ocular lens by Sapphire II‐aftobetin eye scan: Correlation with amyloid PET imaging in mild cognitive impairment (MCI) and mild Alzheimer’s disease (AD)Goldstein, Lee E. / Wilke, Susanne / Goodman, Ira J. / Nilan, Dennis / Sadowsky, Carl H. et al. | 2021
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Plasma Aβ40, Aβ42 and Aβ‐clearance proteins as blood biomarkers for Alzheimer's disease, subjective cognitive decline, and MCIIto, Hitomi / Shan, Liu / Hata, Naoko / Korenaga, Tatsumi / Suzuki, Hideaki / Meno, Kohji / Takihara, Takanobu / Akatsu, Hiroyasu / Matsukawa, Noriyuki / Asada, Takashi et al. | 2021
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Association of physical strength and AD biomarkers in cognitively unimpaired patientsKim, Aelim / Kim, Woo‐Ram / Noh, Young et al. | 2021
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Quantitative amyloid PET in the AMYPAD diagnostic and patient management studyBuckley, Christopher / Gispert, Juan Domingo / Altomare, Daniele / Moro, Christian / Bullich, Santiago / Caprioglio, Camilla / Scheltens, Philip / Van Berckel, Bary N.M. / Collij, Lyduine E. / Alves, Isadora Lopes et al. | 2021
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Mass spectrometric measurement of six site‐specific tau phosphorylations in CSF and blood of Alzheimer's disease patientsMontoliu‐Gaya, Laia / Ashton, Nicholas J. / Benedet, Andréa Lessa / Rodriguez, Juan Lantero / Brinkmalm, Gunnar / Karikari, Thomas K. / Kern, Silke / Rosa‐Neto, Pedro / Zetterberg, Henrik / Blennow, Kaj et al. | 2021
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Transcriptomics, metabolomics, lipidomics, metabolic flux and mGWAS analyses of sphingolipid pathway highlights novel drugs for Alzheimer’s diseaseBaloni, Priyanka / Arnold, Matthias / Moreno, Herman / Nho, Kwangsik / Kastenmüller, Gabi / Suhre, Karsten / Buitrago, Luna / Louie, Gregory / Kueider‐Paisley, Alexandra / Saykin, Andrew J. et al. | 2021
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An increase in fatty acid indices in cerebrospinal fluid of mild cognitive impairment precedes a decrease in Alzheimer’sFonteh, Alfred N. / Cipolla, Matthew / Arakaki, Xianghong / Chui, Helena C. / Harrington, Michael G. et al. | 2021
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Assessment of AD‐related plasma biomarkers in diverse ancestral populationsGriswold, Anthony J. / Rajabli, Farid / Garcia‐Serje, Catherine / Hamilton‐Nelson, Kara L. / Adams, Larry D. / Tejada, Sergio / Mena, Pedro Ramon / Starks, Takiyah D. / Whitehead, Patrice L. / Silva‐Vergara, Concepcion et al. | 2021
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Levels of the synaptic proteins PSD‐95, SNAP‐25, and neurogranin are selectively increased in the cerebrospinal fluid of patients with Alzheimer’s diseaseKivisäkk, Pia / Carlyle, Becky C. / Ramirez, Christopher E. / Trombetta, Bianca A. / Mendes, Muriel / Brock, Mary / Rubel, Carrie E. / Czerkowicz, Julie / Graham, Danielle / Arnold, Steven E. et al. | 2021
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In‐depth investigation in tau positron emission tomography tracers off‐target binding with voxel‐to‐voxel correlation analysis of tau and amyloid PET signal to histological iron and tau deposit in non‐Alzheimer tauopathiesChen, Yuheng / Alegro, Maryana / Li, Song / La Joie, Renaud / Shankar, Anubhav / Lee, Wing Hung / Kantamneni, Namrata / Nasar, Rakin / Miller, Bruce L. / Rabinovici, Gil D. et al. | 2021
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Clinical reporting following the quantification of cerebrospinal fluid biomarkers in Alzheimer's disease: An international overviewDelaby, Constance / Teunissen, Charlotte E. / Blennow, Kaj / Alcolea, Daniel / Arisi, Ivan / Amar, Elodie Bouaziz / Beaume, Anne / Bedel, Aurélie / Bellomo, Giovanni / Bigot‐Corbel, Edith et al. | 2021
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TMS for the characterization of different types of dementia disorders: A systematic review and meta‐analysisQuintanilla‐Sanchez, Carolina / Salcido‐Montenegro, Alejandro / Antal, Andrea / Nañez‐Terreros, Homero et al. | 2021
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Relationship between platelet derived growth factor receptor‐β and Alzheimer’s biomarkers in a racially diverse, high‐risk cohortButts, Brittany / Miners, Scott / Kehoe, Patrick G. / Hu, William T. / Huang, Hanfeng / Verble, Danielle D. / Zetterberg, Henrik / Zhao, Liping / Wharton, Whitney et al. | 2021
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Clinical performance of the beta‐amyloid 1‐42/1‐40 ratio determined from automated Lumipulse G1200 cerebrospinal fluid Abeta1‐42 and Abeta1‐40 assays, assessed by concordance with PET imaging statusWinslow, John W. / Martone, Robert L. / Badal, Youssouf W. / Chenna, Ahmed W. / Cai, Suqin W / Sperinde, Jeff W. / Ayonke, Jeric W. / Vergara, Jamie / Yee, Brandon W. / Spiro, Lisa W. et al. | 2021
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Changes in alkaline phosphate and calcium levels during early mild cognitive impairment, indicating a role for bone in the progression of Alzheimer’s diseaseSuryadevara, Vidyani / Monte, Willis S. et al. | 2021
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"Multi‐domain interventions for dementia prevention – A Systematic Review"Castro, Carolina B / Costa, Lais / Dias, Cintia B / Chen, Juliana / Loo, Ruey / Sohrabi, Hamid R / Brown, Belinda M / Martins, Ralph N et al. | 2021
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Event‐Related Delta Oscillations are Diminished in Parkinson’s Disease with Different Cognitive Status: A Longitudinal EEG StudyGündüz, Duygu Hünerli / Çolakoğlu, Beril Dönmez / Güntekin, Bahar / Yener, Gorsev et al. | 2021
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Comparison of latent cognitive reserve markers and a latent marker score in Alzheimer’s diseaseErsoezlue, Ersin / Rauchmann, Boris‐Stephan / Perneczky, Robert / Alzheimer’s Disease Neuroimaging Initiative et al. | 2021
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Unraveling the challenging life experience of persons with mild cognitive impairment: A mixed‐methods studyLin, Rose S.Y. / Li, Polly W.C. / Chau, Patsy P.H. / Yu, Doris S.F. et al. | 2021
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Affective and cognitive deficits in a novel AD mouse model: A role for noradrenaline and inflammationSedgwick, Katie Sarah / Dwyer, Dominic / Good, Mark A / Saito, Takashi et al. | 2021
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Mindfulness is associated with amyloid, tau and cognition in preclinical ADStrikwerda‐Brown, Cherie / Ozlen, Hazal / Binette, Alexa Pichet / Chapleau, Marianne / Villeneuve, Sylvia / PREVENT‐AD Research Group et al. | 2021
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Cultural adaptation and validation of the Addenbrooke’s Cognitive Examination III in a Taiwanese population (T‐ACE‐III) presenting to hospital with suspected dementiaYu, Ruan‐Ching / Mukadam, Naaheed / Kapur, Narinder / Stott, Joshua / Livingston, Gill et al. | 2021
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Fluid intelligence and its neural correlates in early onset mild cognitive impairmentCarbone, Chiara / Bardi, Elisa / Corni, Maria Giulia / Fiondella, Luigi / Salemme, Simone / Vinceti, Giulia / Tondelli, Manuela / Molinari, Maria Angela / Chiari, Annalisa / Zamboni, Giovanna et al. | 2021
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Considerations for designing DLB trialsArmstrong, Melissa J et al. | 2021
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Pilot trial of dronabinol adjunctive treatment of agitation in Alzheimer's disease (THC‐AD)Rosenberg, Paul B. / Outen, John D. / Amjad, Halima / Burhanullah, Haroon / Vandrey, Ryan / Agronin, Marc / Castaneda, Ricardo / Isesalaya, Maria / Walsh, Patricia / Ash, Eleanor T. et al. | 2021
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Changes in subjective and objective cognitive decline in non‐depressed, non‐demented patients with Parkinson's disease: A 1 to 2 years’ follow‐upRattanabannakit, Chatchawan / Wongkanjana, Nutchaphol / Munjit, Rabwas / Warunyuwong, Wikrom / Srivanitchapoom, Prachaya / Senanarong, Vorapun et al. | 2021
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Analysis of cognitive and functional states with relation to variables: A quantitative study in MauritiusDorkhy, Geeta Devi et al. | 2021
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Utility of Birmingham Cognitive Screen (BCoS) to differentiate vascular cognitive impairment and Alzheimer’s diseaseApostolopoulos, Dimitrios / Bickerton, Wai‐Ling / Brett, Lucy / Laverick, Rosanna / Rotshtein, Pia / Hosseini, Akram A. et al. | 2021
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Circadian rhythm disturbance in agitation of Alzheimer's diseaseRosenberg, Paul B. / Outen, John D. / Spira, Adam P. / Zipunnikov, Vadim / Wanigatunga, Sarah K. / Wu, Mark N. et al. | 2021
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Self‐reflection is associated with markers of Alzheimer’s disease in cognitively unimpaired older adultsDemnitz‐King, Harriet / Chocat, Anne / Collette, Fabienne / Dautricourt, Sophie / Gonneaud, Julie / Jessen, Frank / Klimecki, Olga M / Salmon, Pierre Krolak / Lutz, Antoine / Molinuevo, Jose Luis et al. | 2021
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Task‐free functional networks related to emotion processing in frontotemporal lobar degenerationCanu, Elisa / Calderaro, Davide / Castelnovo, Veronica / Leocadi, Michela / Basaia, Silvia / Filippi, Massimo / Agosta, Federica et al. | 2021
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Defining physical activity: A comparison of actigraphy monitoring and self‐report measuresVandeBunte, Anna M. / Djukic, Nina / You, Michelle / Fonseca, Corrina / Kramer, Joel H / Casaletto, Kaitlin B et al. | 2021
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Amyloid accumulation associated with worse performance of complex taskKeleman, Audrey A. / Bollinger, Rebecca M. / Ances, Beau M. / Stark, Susan L. et al. | 2021
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Semantic clustering and memory in the everyday problem‐solving of mild cognitive impairment subtypesNayares, Claudia / Bailey, Makayla / Jimenez, Celine / Balakid, Jannine / Lent, David D / Alving, Loren / Woo, Ellen et al. | 2021
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A cognitive composite for genetic frontotemporal dementia: GENFI‐cogPoos, Jackie M. / Nicholas, Jennifer M / Moore, Katrina M / Russell, Lucy L / Peakman, Georgia / Jiskoot, Lize C. / van den Berg, Esther / Papma, Janne M. / Seelaar, Harro / Pijnenburg, Yolande A.L. et al. | 2021
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Using a virtual reality path integration task to investigate entorhinal functioning in individuals with and without subjective cognitive declineAlkan, Merve / Bierbrauer, Anne / Kunz, Lukas / Axmacher, Nikolai / Jessen, Frank et al. | 2021
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Subjective cognitive decline is associated with higher anxiety and depression during the COVID‐19‒related confinementSánchez‐Benavides, Gonzalo / Akinci, Muge / Minguillón, Carolina / Deulofeu, Carme / Salvadó, Gemma / González‐de‐Echávarri, José María / Brugulat‐Serrat, Anna / Suarez‐Calvet, Marc / Sala‐Vila, Aleix / Grau‐Rivera, Oriol et al. | 2021
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Family stories: Subjective cognitive decline profile associated with a familial history of Alzheimer’s diseaseRobertson, Frank / Marx, Hannah / Jacova, Claudia et al. | 2021
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Differentiating memory clinic patients and healthy volunteers using machine‐learning analysis of speech and eye movements during a reading taskSoroski, Thomas / Barral, Oswald / Jang, Hyeju / Newton‐Mason, Sally May / Shajan, Sheetal / Tutt, Pavan / Granby, Saffrin / Rizzo, Matteo / Chui, Diego / Teng, Minnie Y et al. | 2021
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The Women’s Healthy Ageing Project: A pattern of cognitive decline after brain injuryBird, Stefanie / Faux, Noel G / Szoeke, Cassandra et al. | 2021
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Leukotriene receptor antagonist use is associated with slower cognitive decline in Alzheimer’s diseaseXiong, Lisa Y. / Ouk, Michael / Wu, Che‐Yuan / Rabin, Jennifer S. / Lanctôt, Krista L. / Herrmann, Nathan / Black, Sandra E. / Edwards, Jodi D. / Swardfager, Walter et al. | 2021
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The first female engineer at General Motor’s descent into Alzheimer’s with sundowners: A daughter’s scholarly research and case study as caregiverKeely, Amy J et al. | 2021
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Development of educational system for paramedics specializing to dementia elderlies analyzed by artificial intelligence and its learning effectsHonda, Miwako / Une, Saki / Gineste, Yves / Nakazawa, Atsushi et al. | 2021
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The risks of polypharmacy in ambulatory and home care patients affected with dementia: The PharE StudyGareri, Pietro / Russo, Emilio / Condito, Andrea / De Sarro, Giovambattista et al. | 2021
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Effectiveness of home‐based telerehabilitation in mild to moderate Alzheimer’s disease: A randomised controlled studyMenengiç, Kübra Nur / Yeldan, İpek / Cınar, Nilgun / Şahiner, Türker AH et al. | 2021
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Memory improvement effects of Ganoderma mediosinense in mice via its anticholinergic and antioxidant activitiesSingh, Varinder / Arora, Sandeep / Kaur, Ravneet / Shri, Richa et al. | 2021
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Heparan sulfate: In vitro and in vivo proof of efficacy of this new therapeutic strategy for halting Alzheimer disease‐related tauopathy developmentMaïza, Auriane / Douaron, Gael Le / Soria, Aida Muntsant / Li, Yong / Ramakrishnan, Kithika / Ouidja, Mohand Ouidir / Fifre, Alexandre / Chantepie‐Laborde, Sandrine / Jospin, Estelle / Laffray, Xavier et al. | 2021
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E2511, a novel small compound TrkA allosteric modulator, induces a specific trophic signaling via direct binding to TrkA, and can reverse the loss of choline acetyltransferase (ChAT) positive neurons in transgenic models of ADTomioka, Takeyasu / Moriyama, Yoshiyuki / Hiramatsu, Naoki / Kosasa, Takashi / Kondo, Keita / Wakita, Hisashi et al. | 2021
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Impact of protocol design on between scale discrepancies in early AD clinical trialsMiller, David S. / Kott, Alan et al. | 2021
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Baseline characteristics for CLARITY AD: A phase 3 placebo‐controlled, double‐blind, parallel‐group, 18‐month study evaluating lecanemab (ban2401) in early Alzheimer's diseaseLynch, Shau Yu / Irizarry, Michael C / Dhadda, Shobha / Li, David JianJun / Kanekiyo, Michio / Bogoslovsky, Tanya / Gee, Michelle / Reyderman, Larisa / Kaplow, June / Rabe, Martin et al. | 2021
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Forecasting progression of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) with digital twinsBertolini, Daniele / Loukianov, Anton D. / Smith, Aaron / Li‐Bland, David / Pouliot, Yannick / Walsh, Jonathan R. / Fisher, Charles K. et al. | 2021
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The neutral sphingomyelinase 2 inhibitor PDDC reduces tau burden in Alzheimer’s disease miceTallon, Carolyn / Bell, Benjamin J / Malvankar, Medhinee / Hollinger, Kristen R / Thomas, Ajit G / Yoo, Seung Wan / Chaudhuri, Amrita Datta / Wu, Ying / Rais, Rana / Haughey, Norman J et al. | 2021
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Neurocognitive effects of acupuncture in dementia: A brief literature reviewNicanord, Ernst J / Raji, Mukaila et al. | 2021
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Using Bayesian hierarchical analysis to combine evidence across outcomes and trialsDickson, Samuel P / Nicodemus‐Johnson, Jessie / Knowlton, Newman / Syndergaard, Tess / Neff, Jacob / Earnshaw, Madison / Hennessey, Sean / Hendrix, Suzanne B. et al. | 2021
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Pimavanserin and concomitant anti‐dementia medication use in patients with neurodegenerative and/or neurovascular disorders: Safety outcomes from pooled clinical data and the HARMONY studyFoff, Erin P. / McEvoy, Bradley / Skoog, Benjamin / Demos, George et al. | 2021
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Improved functional connectivity after a 6‐month ketogenic supplementation in mild cognitive impairmentRoy, Maggie / Edde, Manon / Fortier, Melanie / Croteau, Etienne / Castellano, Christian‐Alexandre / St. Pierre, Valerie / Vandenberghe, Camille / Morin, Marie‐Christine / Langlois, Francis / Bocti, Christian et al. | 2021
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Plasma Aβ 42:40 ratio tracks with changes in brain amyloid PET SUVr in the core and open label extension of the phase 2 proof of concept study ban2401‐g000‐201 following treatment with lecanemab in subjects with early Alzheimer’s diseaseSwanson, Chad J / Kanekiyo, Michio / Kaplow, June / Dhadda, Shobha / Irizarry, Michael C / Koyama, Akihiko / Li, David JianJun / Verbel, David / Gordon, Robert / Heanue‐Travers, Helena et al. | 2021
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Cognitive outcomes of anti‐amyloid‐β monoclonal antibodies in patients with Alzheimer's disease: A systematic review and meta‐analysis of randomized controlled trialsFernandez, Paulo Eduardo Lahoz / Silva, Guilherme Diogo et al. | 2021
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Age and circadian rhythm‐dependent effects of M1 muscarinic acetylcholine receptor positive allosteric modulators and donepezil on sleep‐wake architecture and arousalRussell, Jason K / Bubser, Michael / Newhouse, Paul A / Lindsley, Craig W / Jones, Carrie K et al. | 2021
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Developing human cellular models to understand biological mechanisms linked to AD genetic riskYoung, Jessica E. et al. | 2021
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Proliferating microglia exhibit unique transcriptomal and functional alterations in Alzheimer’s diseaseVillacampa, Nàdia / Sarlus, Heela / Martorell, Paula / Slutzkin, Ilya / Mcmanus, Roisin M. / Beyer, Marc / Segal, Eran / Heneka, Michael T. et al. | 2021
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Influence of chronic microglial activation and aging on the medial septal cholinergic cell number and morphologyGamage, Rashmi Vasundhara / Gyengesi, Erika et al. | 2021
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Spatial transcriptomics of human middle temporal gyrus reveals layer‐specific gene expression in early Alzheimer’s diseaseChen, Shuo / Chang, Yuzhou / Li, Liangping / Serrano, Geidy E / Beach, Thomas G / Duff, Karen E / Ma, Qin / Fu, Hongjun et al. | 2021
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Probiotic Bifidobacterium breve decreases Aβ production via the upregulation of ADAM10 level and attenuates microglia activation in an APP knock‐in mouse model of Alzheimer’s diseaseJung, Cha‐Gyun / Abdelhamid, Mona / Zhou, Chunyu / Taslima, Ferdous / Abdullah, Mohammad / Michikawa, Makoto et al. | 2021
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Lipidome changes due to accumulation of cholesterol via APP‐C99 alters neuronal permeabilityMontesinos, Jorge / Area‐Gomez, Estela et al. | 2021
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The impacts of menopause on a mouse model of co‐morbid metabolic syndrome and Alzheimer’s diseaseAbi‐Ghanem, Charly / Salinero, Abigail E / Gannon, Olivia J / Riccio, David / Mansour, Febronia / Kelly, Richard D / Kordit, David / Wang, Matthew / Kyaw, Nyi‐Rein / Cirrito, John R et al. | 2021
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An integrated systems‐level analysis of the molecular changes resulting from systemic inflammation in Alzheimer’s diseaseMacBean, Lachlan F / Smith, Rebecca G. / Smith, Adam R. / Nicoll, James AR / Boche, Delphine / Lunnon, Katie et al. | 2021
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Spatial pattern of R2 relaxation rate is associated with limbic‐predominant, age‐related, TDP‐43 encephalopathy neuropathological change (LATE‐NC)Tazwar, Mahir / Evia, Arnold M Jr. / Tamhane, Ashish A / Bennett, David A. / Schneider, Julie A. / Arfanakis, Konstantinos et al. | 2021
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Towards holistic theory and therapeutics of Alzheimer's disease: The AD‐DROP ontologyDaly, Timothy / Bourdenx, Mathieu / Henry, Vincent / Epelbaum, Stéphane et al. | 2021
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AIM2 inflammasome mediates hallmark neuropathological alterations and cognitive impairment in a mouse model of vascular dementiaPoh, Luting / Fann, David / Wong, Peiyan / Rajeev, Vismitha / Selvaraji, Sharmelee / Chen, Christopher / Lai, Mitchell Kim Peng / Lim, Hsiu Kim Lina / Arumugam, Thiruma Valavan et al. | 2021
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The majority of the patients with a monogenic predisposition for dementia did not fulfill current criteria for genetic testingVan Der Lee, Sven J / Hulsman, Marc / van Spaendonk, Rosalina M.L. / Cohn‐Hokke, Petra E / van der Flier, Wiesje M / Holstege, Henne / Scheltens, Philip et al. | 2021
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CNTN5 is associated with disease risk and pathology throughout the Alzheimer’s disease continuumDauar, Marina Tedeschi / Picard, Cynthia / Rosa‐Neto, Pedro / Villeneuve, Sylvia / Poirier, Judes / Prevent‐AD Research Group et al. | 2021
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Cell type‐specific gene expression changes in Alzheimer’s patients with varying levels of cerebral amyloid angiopathyPatel, Tulsi / Udine, Evan / Wang, Xue / Allen, Mariet / Is, Ozkan / Tutor‐New, Frederick Q / Carnwath, Troy / Deniz, Kaancan / Lincoln, Sarah J. / Nguyen, Thuy et al. | 2021
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Astrocyte‐secreted TIMP‐1 binds to CD63 and differentially phosphorylates Akt in protecting neurons and promoting cognitive recovery in 5xFAD miceSarkar, Sukanya / Paidi, Ramesh Kumar / Biswas, Subhas Chandra et al. | 2021
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Copy number variation (CNV) identification and association study on 3,928 Alzheimer’s disease whole genome sequencing data from the Alzheimer’s Disease Sequencing Project (ADSP)Lee, Wan‐Ping / Conery, Mitchell / Valladares, Otto / Chou, Yi‐Fan / Leung, Yuk Yee / Kuzma, Amanda B / Tucci, Albert A / Brucker, Amanda / Lu, Wenbin / Schellenberg, Gerard D. et al. | 2021
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TREM2‐independent neuroprotection is mediated by monocyte‐derived macrophages in a mouse model of Alzheimer’s diseaseDvir‐Szternfeld, Raz / Castellani, Giulia / Arad, Michal / Cahalon, Liora / Colaiuta, Sara P / Keren‐Shaul, Hadas / Croese, Tommaso / Ulland, Tyler K. / Colonna, Marco / Weiner, Assaf et al. | 2021
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Axonal transport dynamics explain directional bias in tau depositionTorok, Justin / Maia, Pedro D. / Verma, Parul / Mezias, Christopher / Raj, Ashish et al. | 2021
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A novel therapeutic approach to treat Alzheimer's disease: The brain‐specific signal peptide peptidase‐like 2b (SPPL2b)Tambaro, Simone / Riccardo, Maccioni / Zerial, Stefania / Wagener, Annika / Andrade‐Talavera, Yuniesky / Fisahn, André / Mentrup, Torben / Schröder, Bernd / Nilsson, Per et al. | 2021
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Increased ERb expression during ageing could be neuroprotective against Alzheimer’s disease development in the male but not the female brainAlmutairi, Jawza A / Gee, Julia M / Kidd, Emma J et al. | 2021
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Elucidating the neurodegnerative sequelae leading to VCID pathologyEarly, Alexandria N / Weekman, Erica M / Sudduth, Tiffany L / Price, Brittani R / Woolums, Abigail E / Hawthorne, Danielle / Seaks, Charles E IV / Wilcock, Donna M et al. | 2021
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Extensive genetic and phenotypic description of MAPT p.R406W in the Flanders‐Belgian populationGossye, Helena / Van Mossevelde, Sara / van der Zee, Julie / Vermeiren, Yannick / Sieben, Anne / De Roeck, Naomi / De Bleecker, Jan / De Deyn, Peter Paul / Cras, Patrick / Engelborghs, Sebastiaan et al. | 2021
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Epigenome‐wide association study of hippocampal volumeLiu, Dan / Aziz, N. Ahmad / Estrada, Santiago / Reuter, Martin / Breteler, Monique M.B. et al. | 2021
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Cancer history associates with a lower burden of dementia and Alzheimer’s‐type neuropathology in autopsied research volunteersKaranth, Shama D / McDowell, Jaclyn K / Nelson, Peter T / Katsumata, Yuriko / Kryscio, Richard J / Schmitt, Frederick A / Fardo, David W. / Abner, Erin L et al. | 2021
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Mapping tau burden and neuronal loss in MAPT‐associated frontotemporal lobar degenerationGiannini, Lucia AA / Ohm, Daniel T / Rozemuller, Annemieke J.M. / Suh, EunRan R / Van Deerlin, Vivianna M / Trojanowski, John Q / Lee, Eddie B / van Swieten, John C / Grossman, Murray / Seelaar, Harro et al. | 2021
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A new biochemical method for ultra‐purification of amyloids from Alzheimer’s disease brain tissuesUpadhyay, Arun / Siemer, Ansgar / Langen, Ralf / Vassar, Robert J. / Savas, Jeffrey N et al. | 2021
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Amyloid‐β analysis from brain cells using microfluidics and mass spectrometryVillarreal, Jorvani Cruz / Egatz‐Gomez, Ana / Liu, Jiawei / Ros, Robert / Noutsios, George T. / Sandrin, Todd R. / Coleman, Paul D. / Ros, Alexandra et al. | 2021
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A scoping review of the association of social disadvantage and vascular neuropathologyKeller, Sarah A / Hansmann, KJ / Powell, Ryan / Kind, Amy J. et al. | 2021
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Cholinergic preservation in the oldest‐old prefrontal cortexMaxwell, Selena P / Cash, Meghan K / Darvesh, Sultan et al. | 2021
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High‐fat diet generally exacerbates, but is sometimes protective against, cognitive dysfunction in female AD mice depending on genetic backgroundDunn, Amy R / Dai, Miko / Bridges, Dave / O'Connell, Kristen MS / Kaczorowski, Catherine C. et al. | 2021
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Elucidating the temperature exposome in Alzheimer’s diseaseMcFadden, Samuel / Findley, Caleigh A. / Cox, MaKayla F. / Fang, Yimin / Bartke, Andrzej / Hascup, Erin R. / Hascup, Kevin N. et al. | 2021
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Estrogen transcriptomic regulation of brain bioenergetics and metabolism is cell‐type‐specific and estrogen‐receptor‐subtype‐dependentWang, Yiwei / Shang, Yuan / Yin, Fei / Brinton, Roberta Diaz et al. | 2021
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Accumulation of periodic‐acid Schiff granules is increased in the presence of humanized amyloid betaForner, Stefania / Javonillo, Dominic I / Tran, Kristine M / Phan, Jimmy / Da Cunha, Celia / Baglietto‐Vargas, David / Kawauchi, Shimako / Tenner, Andrea J / LaFerla, Frank / MacGregor, Grant R et al. | 2021
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Evaluation of late‐onset Alzheimer’s disease risk variants in mouse modelsSasner, Michael / Oblak, Adrian L / Garceau, Dylan / Kotredes, Kevin P / Soni, Disha / Lin, Peter Bor‐Chian / Preuss, Christoph / Uyar, Asli / Pandey, Ravi S / Carter, Gregory W et al. | 2021
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Alzheimer’s disease polygenic scores predict changes in executive function across 12 years in late middle ageGustavson, Daniel E. / Reynolds, Chandra A. / Hohman, Timothy J. / Jefferson, Angela L. / Elman, Jeremy A. / Panizzon, Matthew S. / Lyons, Michael J. / Franz, Carol E. / Kremen, William S. et al. | 2021
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Developing a functionally valid model of the TREM2‐APOE complex to better understand its role in Alzheimer’s diseaseDean, Hunter B / Brett, Thomas / Roberson, Erik D. / Song, Yuhua et al. | 2021
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Targeting aggregated tau turnover as a therapeutic strategyCroft, Cara L / Goodwin, Marshall S / Ryu, Daniel H / Lessard, Christian B / Tejeda, Giancarlo / Marrero, Marc / Vause, Ava / Paterno, Giavanna / Cruz, Pedro E / Lewis, Jada et al. | 2021
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Porphyromonas gingivalis outer membrane vesicles as the major drivers of and source for the toxic insult and iron accumulation/deposition in Alzheimer’s diseaseNara, Peter Lloyd et al. | 2021
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Bulk and single‐nucleus analysis of the 3xTgAD cortex and hippocampus transcriptomeRezaie, Narges / Gutierrez, Gabriela Balderrama / Liang, Heidi Yahan / Forner, Stefania / Mortazavi, Ali / MODEL AD et al. | 2021
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Synaptosomal versus cytosolic microRNAs and synapse function in Alzheimer’s diseaseKumar, Subodh / Orlov, Erika / Reddy, P. Hemachandra et al. | 2021
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An assessment of the neurobehavioural effect of cannabidiol and omega‐3 in high‐fat–diet‐induced dementia in albino miceAbi, Innocent / Adeniyi, Stephen Olasupo / Imam, Mustapha Umar et al. | 2021
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TDP‐43 proteinopathy in the retina of patients with frontotemporal lobar degenerationDijkstra, Anke A. / Morrema, Tjado / Verbraak, Frank / de Boer, Johannes / de Ruyter, Frederique Jasmine Hart / Pijnenburg, Yolande A.L. / Rozemuller, Annemieke J.M. / Bouwman, Femke H. / den Haan, Jurre / Hoozemans, Jeroen J. et al. | 2021
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Neuropathological signaling in AD human induced neuronsStutzmann, Grace E / Marr, Robert / Mustaly, Sarah H / Schrank, Sean et al. | 2021
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Localization of AD biomarker phospho‐tau proteins in the brains of an App knock‐in mouse model of Aβ amyloidosisHirota, Yu / Sakakibara, Yasufumi / Ibaraki, Kyoko / Takei, Kimi / Iijima, Koichi M. / Sekiya, Michiko et al. | 2021
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IPCS‐derived APPswe mutant pericytes produce beta‐amyloid and induce the activation of co‐cultured astrocytesWu, Ying Chieh / Rolova, Taisia / Lehtonen, Šárka / Koistinaho, Jari et al. | 2021
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Microstructural alterations of the locus coeruleus‐entorhinal cortex pathway in Alzheimer’s disease and behavioral variant frontotemporal dementiaQuattrini, Giulia / Pini, Lorenzo / Galazzo, Ilaria Boscolo / Pizzini, Francesca B / Pievani, Michela et al. | 2021
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A proteome‐derived temporal model of neurodegeneration in older brainsHeath, Laura M / Gockley, Jake / Cary, Gregory A. / Wiley, Jesse C / Poehlman, William L. / Carter, Gregory W / Greenwood, Anna K / Mangravite, Lara M et al. | 2021
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Classification of Alzheimer’s disease by using tau PET images and deep convolutional neural networksOzsahin, Ilker / Sekeroglu, Boran / Butler, Tracy et al. | 2021
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Towards clinical application of tau PET: PrognosticsCho, Hanna / Baek, Minsuk / Kim, Han‐Kyeol / Lee, Jae Hoon / Chun, Joong‐Hyun / Ryu, Young Hoon / Lyoo, Chul Hyoung et al. | 2021
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Simulation of microvascular MRI signal changes in the presence of amyloid‐beta plaques or microbleedsJahng, Geon‐Ho / Yoo, Chang Hyun / Jin, Seokha / Lee, DongKyu / Cho, HyungJoon et al. | 2021
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Lesion‐network mapping of tau accumulation is predictive of domain‐specific cognitive deficits in Alzheimer’s diseaseLuan, Ying / Franzmeier, Nicolai / Rubinski, Anna / Ewers, Michael et al. | 2021
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Retinal microvasculature and neurodegenerative changes in males vs females with Alzheimer’s disease: A case‐control studyMirzania, Delaram / Thompson, Atalie C. / Robbins, Cason B. / Soundararajan, Srinath / Liu, Andy / Johnson, Kim / Grewal, Dilraj S. / Fekrat, Sharon et al. | 2021
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Radial peripapillary capillary network microvascular changes in Alzheimer's disease, mild cognitive impairment, and cognitively healthy controlsRobbins, Cason B. / Grewal, Dilraj S. / Soundararajan, Srinath / Stinnett, Sandra / Liu, Andy / Johnson, Kim / Fekrat, Sharon et al. | 2021
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Age‐related atrophy persists after screening for preclinical Alzheimer diseaseKoenig, Lauren N. / LaMontagne, Pamela J. / Glasser, Matthew F. / Gordon, Brian A. / Morris, John C. / Shimony, Joshua S. / Benzinger, Tammie L.S. et al. | 2021
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New applications of diffusion model based prediction of pathological brain alterations: Introducing amyloid‐tau interactionsRaj, Ashish / Anand, Chaitali et al. | 2021
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Phenotype‐dependent relationships between cortical macro‐ and micro‐structural neurodegeneration in frontotemporal lobar degenerationPlacek, Katerina / Anania, Vincenzo / Van Phan, Thanh / de Barros, Nuno Pedrosa / Billiet, Thibo / Ribbens, Annemie / Simen, Arthur / Schwarz, Adam J. et al. | 2021
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Longitudinal associations between racial discrimination and brain aging among black older adultsZahodne, Laura B. / Sharifian, Neika / Kraal, A. Zarina / Morris, Emily P. / Sol, Ketlyne / Zaheed, Afsara B. / Meister, Lindsey / Mayeux, Richard / Schupf, Nicole / Manly, Jennifer J. et al. | 2021
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ATN classification in dementia with Lewy bodies: Association with clinical profile, cognitive decline and survivalvan de Beek, Marleen / Ooms, Floor A.H. / Ebenau, Jarith L. / Barkhof, Frederik / Scheltens, Philip / Teunissen, Charlotte E. / van Harten, Argonde C. / van der Flier, Wiesje M / Lemstra, Afina W. et al. | 2021
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Initial biological evaluation of a novel microtubule‐based PET ligand in rodent and NHP models of ADDamuka, Naresh / Macauley, Shannon L. / Orr, Miranda E. / Shively, Carol A. / Lockhart, Samuel N. / Bansode, Avinash / Frye, Brett M. / Mintz, Akiva / Kim, Jeongchul / Register, Thomas C. et al. | 2021
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Sex differences in brain aging among adults with APOE4 genetic risk and family history of Alzheimer’s diseaseSubramaniapillai, Sivaniya / Rajagopal, Sricharana / Snytte, Jamie / Otto, Ross / Einstein, Gillian / Rajah, Natasha / the PREVENT‐AD Research Group et al. | 2021
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A global resilience score captures associations with AD pathology and predicts cognitive decline in cognitively healthy older adultsDobyns, Lindsey / Zhuang, Kailin / Baker, Suzanne L. / Jagust, William J. / Harrison, Theresa M. et al. | 2021
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Vascular and inflammatory plasma biomarkers correlate with human post‐mortem cerebral vascular pathologyWinder, Zachary / Lee, Tiffany / Abner, Erin L. / Nelson, Peter T. / Neltner, Janna / Jicha, Gregory A. / Wilcock, Donna M. et al. | 2021
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Amyloid and tau PET imaging studies as a clinical prognostic marker in Alzheimer’s diseaseKim, Han‐Kyeol / Baek, Min Seok / Lee, Jae Hoon / Chun, Joong‐Hyun / Ryu, Young Hoon / Cho, Hanna / Lyoo, Chul Hyoung et al. | 2021
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Relationship between brain tissue loss and levels of blood biomarkers in patients with Alzheimer’s diseaseJahng, Geon‐Ho / Lee, Jiyoon / Rhee, Hak Young / Ryu, Chang‐Woo / Choe, Wonchae et al. | 2021
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Longitudinal PET imaging identifies earliest stages of Aβ accumulation in Down syndromeZammit, Matthew D. / Tudorascu, Dana L. / Laymon, Charles M. / Cohen, Ann D. / Zaman, Shahid / Ances, Beau M. / Hartley, Sigan L. / Johnson, Sterling C. / Stone, Charles K. / Mathis, Chester A. et al. | 2021
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Baseline CSF phosphorylated tau as an indicator of subsequent tau accumulation on tau PETCogswell, Petrice M / Wiste, Heather J. / Mielke, Michelle M. / Schwarz, Christopher G. / Weigand, Stephen D / Lowe, Val J / Therneau, Terry M. / Knopman, David S. / Graff‐Radford, Jonathan / Vemuri, Prashanthi et al. | 2021
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Individualized MR‐based prediction of cognitive performance in subjects at risk of dementiaNemali, Aditya Sai Ram / Yakupov, Renat / Schütze, Hartmut / Spottke, Annika / Ramirez, Alfredo / Schneider, Anja / Metzger, Coraline D. / Christoph, Laske / Bittner, Daniel / Brosseron, Frederic et al. | 2021
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Beyond WMH volume: Coalescence score as a new measure of cerebral small‐vessel disease patternMcPhillie, Ross / Barnes, Jo / Tillin, Therese / Chaturvedi, Nishi / Hughes, Alun D. / Jäger, H. Rolf / Sudre, Carole H. et al. | 2021
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A case with early onset Alzheimer’s disease with amyloid uptake not only in cerebrum but also in cerebellumLee, Sunju / Jo, Sungyang / Kim, Hyung‐Ji / Lee, Jae‐Hong et al. | 2021
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Cerebral white matter microstructure in superagers: A diffusion MRI study of a population over the age of 80 with youthful episodic memoryPascual, Marta Garo / Zhang, Linda / Strange, Bryan A. et al. | 2021
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The impact of accuracy on functional neural correlates of the useful field of view (UFOV) taskKraft, Jessica N. / Albizu, Alejandro / O'Shea, Andrew / Hausman, Hanna K. / Evangelista, Nicole D. / Boutzoukas, Emanuel / Hardcastle, Cheshire / Van Etten, Emily J. / Bharadwaj, Pradyumna K. / Song, Hyun et al. | 2021
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Decreased purine metabolite levels in cerebrospinal fluid of transgenic cerebral amyloid angiopathy ratsvan den Berg, Emma / Van Nostrand, William E. / Peters, Tessa M.A. / de Boer, Siebolt / Coene, Karlien L.M. / Engelke, Udo F.H. / Kuiperij, H. Bea / Verbeek, Marcel M. et al. | 2021
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Association of enlarged perivascular spaces (ePVS) and MRI markers of small vessel disease (SVD) and neurodegeneration in the Florida Vascular Imaging Phenotypes (FL‐VIP) Study of AD RiskHaq, Ihtsham U. / Del Brutto Andrade, Victor / Goryawala, Mohammed / Saporta, Anita Seixas Dias / Merritt, Stacy S. / Camargo, Christian / Agudelo, Christian / Ariko, Taylor / Dong, Chuanhui / Loewenstein, David et al. | 2021
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Comparative analysis of cerebrospinal fluid markers and multimodal imaging in predicting Alzheimer’s disease progressionRomano, Michael F. / Balachandra, Akshara / Zhou, Xiao / Jadick, Michalina / Qiu, Shangran / Nijhawan, Diya / Chin, Sang P. / Au, Rhoda / Kolachalama, Vijaya B. et al. | 2021
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Despite heightened risk of cognitive decline, no evidence of local atrophy in people with subjective cognitive decline compared to normal controls in ADNIMorrison, Cassandra / Dadar, Mahsa / Shafiee, Neda / Collins, Louis et al. | 2021
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Determinants of enlarged perivascular spaces (ePVS) on MRI: The Florida Vascular Imaging Phenotypes (FL‐VIP) Study of AD riskRundek, Tatjana / Brutto, Victor Del / Goryawala, Mohammed / Saporta, Anita Seixas Dias / Merritt, Stacy S. / Camargo, Christian / Agudelo, Christian / Ariko, Taylor / Dong, Chuanhui / Loewenstein, David et al. | 2021
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Tracing individual trajectory of longitudinal tau spreading in deep latent spaceKim, Sohee / Cho, Hanna / Lee, Wha Jin / Kim, Sung‐Woo / Lyoo, Chul Hyoung / Seong, Joon‐Kyung et al. | 2021
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Genetically identical twins are highly similar in levels and spatial distribution of tau pathology: A [18F]flortaucipir PET studyCoomans, Emma M / Tomassen, Jori / Ossenkoppele, Rik / Golla, Sandeep SV / den Hollander, Marijke E / Collij, Lyduine E. / Weltings, Emma / Hoogland, Nina / Wolters, Emma E / Windhorst, Albert D. et al. | 2021
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Apolipoprotein L1 is increased in frontotemporal lobar degeneration postmortem brain tissue but not in cerebrospinal fluidHok‐A‐Hin, Yanaika S. / Dijkstra, Anke A. / Rabano, Alberto / Hoozemans, Jeroen J. / Castillo, Lucia / Pijnenburg, Yolande A.L. / Teunissen, Charlotte E. / Del Campo, Marta et al. | 2021
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Associations between amygdala volume and trajectories of neuropsychiatric symptoms in Alzheimer’s disease and dementia with Lewy BodiesJaramillo‐Jimenez, Alberto / Giil, Lasse Melvær / Tovar, Diego / Borda, Miguel German / Ferreira, Daniel / Brønnick, Kolbjørn / Oppedal, Ketil / Aarsland, Dag et al. | 2021
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Comparison of diffusion weighted, imaging‐derived, fractional anisotropy with a novel MRI contrast‐weighted ratio method for measuring myelin in older adults at risk for Alzheimer’s diseasePrice, Lauren Rose / Deardorff, Rachael / Wu, Yu‐Chien / McDonald, Brenna C. / West, John D. / Risacher, Shannon L. / Saykin, Andrew J. et al. | 2021
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White matter fiber density for vocabulary better maintained than fluid abilities in agingGazes, Yunglin / Li, Ruiyang / Mensing, Ashley / Babukutty, Reshma S. / Noofoory, Diala / Nazario, Geneva Hidalgo / Langfield, Christopher / Sakhardande, Jayant / Lee, Seonjoo et al. | 2021
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Predicting memory in preclinical AD from resting‐state functional connectivityFountain‐Zaragoza, Stephanie / Heshung, Liu / Jensen, Jens H. / Helpern, Joseph A. / Benitez, Andreana et al. | 2021
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White matter tract integrity, but not amyloid burden, is related to cognition in cognitively normal older adultsPettigrew, Corinne / Soldan, Anja / Alm, Kylie H. / Bakker, Arnold / Zhu, Yuxin / Wang, Mei‐Cheng / Kutten, Kwame / Bilgel, Murat / Miller, Michael I. / Faria, Andreia et al. | 2021
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Blood pressure is associated with advanced brain aging patterns on MRI in midlife: The CARDIA StudyDintica, Christina S. / Habes, Mohamad / Erus, Guray / Vittinghoff, Eric / Davatzikos, Christos / Nasrallah, Ilya M / Launer, Lenore J. / Sidney, Stephen / Yaffe, Kristine et al. | 2021
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The interactive effect of MCI subtype and white‐matter hyperintensity load on the expression of large‐scale neurofunctional networksDe Marco, Matteo / Vettore, Martina / Pallucca, Claudia / Bendini, Matteo / Gallucci, Maurizio / Venneri, Annalena et al. | 2021
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Self‐reported history of estrogen hormone therapy differentiates rates of amyloid accumulation (PiB‐PET) relative to males: Findings from the Harvard Aging Brain StudyRubinstein, Zoe B. / Buckley, Rachel F. / Scott, Matthew R. / Manning, Lyssa K. / Mayblyum, Danielle V. / Thibault, Emma G. / Jacobs, Heidi I.L. / Farrell, Michelle E. / Properzi, Michael J. / Rabin, Jennifer S. et al. | 2021
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Tau pathology progression across PET‐based stages of regional amyloid depositionMoscoso, Alexis / Grothe, Michel J. / Schöll, Michael et al. | 2021
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Longitudinal FDG‐PET and FTP‐PET demonstrates the relationship between glucose metabolism and tau accumulation in Alzheimer’s disease atrophy‐associated brain regions in cognitively normal older adultsCrook, Harry / Nowell, Joseph / Raza, Sanara / Edison, Paul et al. | 2021
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Abnormal metabolic brain network in behavioral variant of frontotemporal dementiaRus, Tomaž / Ležaić, Luka / Emeršič, Andreja / Kramberger, Milica G. / Pirtošek, Zvezdan / Eidelberg, David / Trost, Maja et al. | 2021
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α‐Synuclein in oligodendroglia and neuron‐derived blood exosomes distinguishes between synucleinopathiesDutta, Suman / Hornung, Simon / Kruayatidee, Adira / Maina, Katherine M / del Rosario, Irish / Paul, Kimberly / Palma, Jose Alberto / Perlman, Susan L. / Poon, Wayne W. / Gylys, Karen H et al. | 2021
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Microglial activation and tau propagate jointly across Braak stagesPascoal, Tharick A. / Benedet, Andréa Lessa / Ashton, Nicholas J. / Kang, Min Su / Therriault, Joseph / Chamoun, Mira / Lussier, Firoza Z. / Tissot, Cécile / Ottoy, Julie / Mathotaarachchi, Sulanta et al. | 2021
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Ethnic differences in the frequency of β‐amyloid deposition in cognitively normal individualsKim, Jaeho / Jung, Sang‐Hyuk / Choe, Yeongsim / Kim, Soyeon / Kim, Beomsu / Kim, Hang‐Rai / Son, Sang Joon / Hong, Chang Hyung / Na, Duk L. / Kim, Hee Jin et al. | 2021
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The heterogeneous brain: Mapping individualised patterns of atrophy in Alzheimer’s disease using spatial normative modelsVerdi, Serena / Kia, Seyed Mostafa / Marquand, Andre F. / Schott, Jonathan M. / Cole, James H. / Alzheimer’s Disease Neuroimaging Initiative et al. | 2021
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Differential impact of sub‐threshold amyloid‐beta deposition on gray matter volume for cognitively normal older adults according to APOE genotype: Whole brain voxel‐wise analysisKang, Dong Woo / Lim, Hyun Kook / Wang, Sheng‐Min / Um, Yoo Hyun et al. | 2021
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Differential impact of sub‐threshold amyloid‐beta deposition on regional homogeneity for cognitively normal older adults according to APOE genotype: Whole brain voxel‐wise analysisKang, Dong Woo / Lim, Hyun Kook / Wang, Sheng‐Min / Um, Yoo Hyun et al. | 2021
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Quantifying perivascular space in Alzheimer's disease by MRI relaxometryZhou, Liangdong / Nguyen, Thanh D. / Wegiel, Jarek / Li, Yi et al. | 2021
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The impact of a global pandemic on persons living with dementia and their care partners: An analysis of 417 survey responsesTam, Mallorie T / Dosso, Jill A / Robillard, Julie M et al. | 2021
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Impact of an intergenerational training program in the use of information and communication technologies for older adults who receive cognitive intervention in the context of a Covid‐19 pandemic: Preliminary resultsFeldberg, Carolina / Crivelli, Lucia / Tartaglini, María Florencia / Martin, Maria Eugenia / Garcia, Lydia Moya / Hermida, Paula Daniela / Natalia, Irrazabal / Somale, Maria Veronica / Sevlever, Gustavo / Allegri, Ricardo Francisco et al. | 2021
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Attitudes towards screening for cognitive dysfunction: Interviews with Latinx adults with type 2 diabetesCuevas, Heather E / Zuñiga, Julie / Morgan, Stephanie E / Ganucheau, Grace E et al. | 2021
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Mid‐life physical activity and late‐life cognitive performance among American Indians in the Strong Heart StudyCarty, Cara L / Noonan, Carolyn / Muller, Clemma / Suchy‐Dicey, Astrid M / Fretts, Amanda M / Verney, Steven P / Howard, Barbara / Buchwald, Dedra et al. | 2021
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The impact of pandemic‐related measures on COVID‐negative dementia inpatientsBukala, Bernard R / Carpenter, Kilda J / Fox, Willow / Reyes, Demi / Sanghvi, Hazel / Vickers, Philip et al. | 2021
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Learning climate in long‐term care facilities for people with dementiaHartstra, Egbert / Prins, Marleen / Overbeek, Anouk / van der Roest, Henriëtte G et al. | 2021
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Exploring the experiences of living at risk of familial frontotemporal dementiaGreaves, Caroline V / Stott, Joshua / Rohrer, Jonathan D et al. | 2021
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Social network characteristics moderate associations between cortical thickness and cognitive functioning in older adultsSharifian, Neika / Zaheed, Afsara B / Morris, Emily P / Sol, Ketlyne / Manly, Jennifer J / Schupf, Nicole / Mayeux, Richard / Brickman, Adam M / Zahodne, Laura B et al. | 2021
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Social contact, social participation, and their changes among elderly people in the United States during the COVID‐19 pandemicZhang, Yun / Luo, Amber / Hou, Luke / Clouston, Sean AP et al. | 2021
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A perspective from ethnomusicology: How to methodologically choose the correct music globally to awaken memories in the Alzheimer's patientPillay, Jayendran et al. | 2021
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Engaging people with lived experience in peer review: Expanding the role of citizen reviewersJaggers, Kaitlyn / Badali, Jocelyn / Guimond, Josée / Sivananthan, Saskia et al. | 2021
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The impact of COVID‐19 outbreak on individuals with Alzheimer’s disease: Information released through online newsPark, Eunsun / Kollia, Betty / Basch, Corey et al. | 2021
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Memory advocate peers: Piloting a sustainable, replicable, volunteer peer mentor program to support individuals newly diagnosed with dementia and their care partnersWalter, Sarah / Cisek, Edward / Taylor, James / Taylor, Geri / Tornatore‐Mikesh, Eleonora C / Levine, Jed et al. | 2021
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Polypharmacy is associated with functional decline in Alzheimer’s disease and Lewy body dementiaBorda, Miguel German / Tovar, Diego / Sonnesyn, Hogne / Osterhus, Ragnhild / Aarsland, Dag et al. | 2021
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Anger in family caregivers of people with behavioral variant frontotemporal dementia versus Alzheimer’s diseaseChen, Kuan‐Hua et al. | 2021
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The Brain Health Champion (BHC) Study, COVID‐19 sub‐study: The impact of COVID‐19 on behaviors adopted following interventions to promote brain‐healthy activitiesMcFeeley, Brittany / Krivanek, Taylor / Nicastri, Casey M / Daffner, Kirk R / Gale, Seth A et al. | 2021
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The effect of mindfulness‐based interventions on cognitive deficits from mild cognitive impairmentMahabir‐Walston, Dianna / Noblitt, James R / Graves, James et al. | 2021
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Ca2+/Calcineurin‐mediated release of exosomal miR‐23a regulates astrocyte‐neuron cross‐talk and protects against neuroinflammation and neurodegenerationBhattacharyya, Pallabi / Biswas, Subhas Chandra et al. | 2021
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Investigating changes in the proteostasis capabilities of iPSC‐neurons during development and in FTD using iPSC‐neurons with MAPT mutationsLines, Georgie / Arber, Charles / Preza, Elisavet / Leckey, Claire Alexandra / Myeku, Natura / Casey, Jackie M. / Perkinton, Michael / Wray, Selina et al. | 2021
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Microglia subtype transcriptomes differ between Alzheimer Disease and control human postmortem brain samplesPrater, Katherine E / Green, Kevin J / Chiou, Kenneth L / Smith, Carole L / Sun, Wei / Shojaie, Ali / Heath, Laura M / Rose, Shannon / Keene, C. Dirk / Logsdon, Benjamin A et al. | 2021
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TDP‐43 aggregation and inhibition using antibodies targeting RRM2‐CTD domainArias, Carlos Quintero / Esposto, Josephine C / Martic, Sanela et al. | 2021
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Astrocytic BMAL1 regulates protein aggregation in mouse models of alpha‐synuclein and tau pathologySheehan, Patrick W. / Kanan, Michael / Benitez, Bruno A. / Harari, Oscar / Davis, Albert A / Musiek, Erik S. et al. | 2021
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TDP‐43 promotes pathological tau phosphorylation and selective neurotoxicity in C. elegansLatimer, Caitlin S. / Keene, C. Dirk / Kraemer, Brian C / Liachko, Nicole F et al. | 2021
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Chronic Microglial Activation and Ageing Reduces the Numbers of Medial Septal Cholinergic Cells and Alters Their MorphologyGamage, Rashmi Vasundhara / Gyengesi, Erika et al. | 2021
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Impact of MAPT mutations on transcriptomic signatures of FTLD brains and patient‐derived pluripotent cell modelsMinaya, Miguel / Martinez, Rita / Eteleeb, Abdallah / Cruchaga, Carlos / Harari, Oscar / Karch, Celeste M. et al. | 2021
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Targeted and untargeted mass spectrometry reveals impact of high fat diet on peripheral amino acid regulation in a mouse model of Alzheimer's diseaseTaylor, Amelia L / Davis, Don E Jr. / Codreanu, Simona G / Harrison, Fiona E. / Sherrod, Stacy D / McLean, John A et al. | 2021
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Characterisation of the biophysical and cellular properties of Tau35, a disease‐associated tau fragmentLyu, Chen et al. | 2021
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Investigating the secretion of small heat shock proteins in reactive astrocytes in Alzheimer’s diseaseYang, Fangjia / Sung, Katherine / Sanchez, Maria Jimenez et al. | 2021
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Data from single nuclei RNA‐sequencing reveals a prodromal gene network response in excitatory neurons of a humanized rat Alzheimer’s disease modelTipton, Allison E / George, Jonique / Ratner, Marcia / Farb, David / Russek, Shelley et al. | 2021
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Circulating klotho is elevated in cerebrospinal fluid, but not serum, among KLOTHO KL‐VS allele carriers at risk for Alzheimer’s diseaseGaitán, Julian M. / Dubal, Dena B. / Okonkwo, Ozioma C. et al. | 2021
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Human Herpesvirus detection and identification in postmortem brain tissue of patients with Alzheimer's diseaseGomez, Johana Jr. / Villegas‐Lanau, Carlos Andrés / Mesa, Ana Sr. et al. | 2021
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Intestinal microbial dysbiosis induced tau accumulation establishes a gut‐brain correlation for pathology Alzheimer's disease in Drosophila melanogasterSrivastav, Ankita / Mohideen, Sahabudeen Sheik et al. | 2021
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Defective proteostasis in patient‐derived iPSC‐astrocytes and neurons carrying a MAPT IVS10+16 mutationMahali, Sidhartha / Karch, Celeste et al. | 2021
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Diseases with abnormal HPA function predict CSF pTau but not CSF Abeta 1‐42 in the EPAD longitudinal cohort studyGregory, Sarah / Ritchie, Craig W / Muñiz‐Terrera, Graciela et al. | 2021
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Does blood pressure variability predict cognitive decline better than hypertension itself? A harmonised analysis of 10 studiesLennon, Matthew J / Lam, Ben CP / Lipnicki, Darren M / Crawford, John D / Sachdev, Perminder S et al. | 2021
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Investigating the relationships between race, cardiovascular disease, mild cognitive impairment, Alzheimer’s disease, and functional outcomes among older former National Football League playersBrett, Benjamin L / Campbell, Hope / Aggarwal, Neelum T / Kerr, Zachary Y / Chandran, Avinash / Walton, Samuel / Mannix, Rebekah / DeFreese, JD / Echemendia, Ruben J / Guskiewicz, Kevin M et al. | 2021
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Projection of net savings to U.S. state Medicaid programs from reduced nursing home utilization due to an Alzheimer’s treatmentMattke, Soeren / Lam, Jenny / Cho, Sang Kyo / Jun, Hankyung / Hanson, Mark et al. | 2021
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Effects of the COVID‐19 pandemic on healthcare and community‐based service use for people living with dementia: Perspectives from dementia care professionalsHunt, Jack FV / Schroeder, Molly / LeCaire, Tamara / O'Toole Smith, Kathleen / Marschall, Katelyn / Walaszek, Art et al. | 2021
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Association of psychological stress with risk of dementia: A systematic review and meta‐analysisFranks, Katherine H / Bransby, Lisa / Saling, Michael M / Pase, Matthew P et al. | 2021
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A possible novel mechanism for cognitive resistance to neurodegeneration: modulation of interneuron activity in the hippocampus after exposure to enriched environmentsKhan, Zuhayr M / Kageyama, Glenn et al. | 2021
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Identifying and triangulating all available evidence on the effect of blood lipids and statins on dementia outcomesMcGuinness, Luke A / Higgins, Julian PT / Ben‐Shlomo, Yoav et al. | 2021
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Health conditions that predict Alzheimer’s disease and vascular dementia: A phenome‐disease association studyBeason‐Held, Lori L / Kerley, Cailey I / Chaganti, Shikha / Moghekar, Abhay / Thambisetty, Madhav / Resnick, Susan M / Landman, Bennett A et al. | 2021
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Relationships between well‐being and cognitive function among Native American, Black, and White participants in the Wisconsin Alzheimer's Disease Research CenterWyman, Mary F / Umucu, Emre / Livingston, Sydnee / Lambrou, Nickolas H / Carter, Fabu P / Van Hulle, Carol A / Johnson, Sterling C / Asthana, Sanjay / Gleason, Carey E / Zuelsdorff, Megan et al. | 2021
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Occupational complexity and neuroimaging measures of structural MRI and PET‐amyloid in a randomized controlled trial: FINGERRydström, Anders / Stephen, Ruth / Kåreholt, Ingemar / Darin‐Mattsson, Alexander / Liu, Yawu / Ngandu, Tiia / Rinne, Juha O / Kemppainen, Nina / Antikainen, Riitta L / Bäckman, Lars et al. | 2021
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Midlife subclinical atherosclerosis and cardiovascular risk factors linked to hypometabolism in Alzheimer’s disease relevant regionsCortes‐Canteli, Marta / Gispert, Juan Domingo / Salvadó, Gemma / Toribio‐Fernández, Raquel / Tristao‐Pereira, Catarina / Sanchez‐Gonzalez, Javier / Ibañez, Borja / Molinuevo, Jose Luis / Fuster, Valentin / The Progression of Early Subclinical Atherosclerosis study et al. | 2021
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The estimation of the global prevalence of dementia from 1990‐2019 and forecasted prevalence through 2050: An analysis for the Global Burden of Disease (GBD) study 2019Nichols, Emma / Vos, Theo et al. | 2021
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Incident stroke in patients with Alzheimer’s disease: A meta‐analysisPinho, João / Miguel, Quintas‐Neves / Imis, Dogan / Reetz, Kathrin / Reich, Arno / Costa, Ana Sofia et al. | 2021
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Patient, disease, and study characteristics in contemporary dementia research: A systematic review on external validityMooldijk, Sanne S / Licher, Silvan / Wolters, Frank J et al. | 2021
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Populacional epidemiological study of dementia in the city of Londrina, Paraná, BrazilNakakogue, Lindsey Mitie / Bersi, Lília Maria Machado / Lepre, Rafael Perusso et al. | 2021
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Individual analysis of reminiscence from nostalgic music videos using text miningUrabe, Mie / Miyata, Chiharu / Fukuda, Hiroko / Yoneda, Sho / Sakai, Katsumi / Kato, Yuka / Kitajima, Kengo / Kashiwa, Yukiko / Sawada, Chikao et al. | 2021
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Target populations for behavioral and clinical interventions to protect cognitive function and brain structure: A two‐age, two‐cohort comparisonZhang, Xuan / Mbangdadji, Djass / Gudnason, Vilmundur / Launer, Lenore J et al. | 2021
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Is there a critical life stage to promote physical activity for preserving cognitive function? Results from a population‐based birth cohortFeter, Natan / Leite, Jayne S / Rombaldi, Airton et al. | 2021