α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease (English)
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In:
Aging Cell
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20
, 12
;
2021
- Article (Journal) / Electronic Resource
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Title:α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease
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Contributors:Tu, Hai‐Yue ( author ) / Yuan, Bao‐Shi ( author ) / Hou, Xiao‐Ou ( author ) / Zhang, Xiao‐Jun ( author ) / Pei, Chong‐Shuang ( author ) / Ma, Ya‐Ting ( author ) / Yang, Ya‐Ping ( author ) / Fan, Yi ( author ) / Qin, Zheng‐Hong ( author ) / Liu, Chun‐Feng ( author )
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Published in:Aging Cell ; 20, 12
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Publisher:
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Publication date:2021-12-01
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Size:17 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 20, Issue 12
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
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Growth hormone receptor gene disruption in mature‐adult mice improves male insulin sensitivity and extends female lifespanDuran‐Ortiz, Silvana / List, Edward O. / Ikeno, Yuji / Young, Jonathan / Basu, Reetobrata / Bell, Stephen / McHugh, Todd / Funk, Kevin / Mathes, Samuel / Qian, Yanrong et al. | 2021
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Sex‐specific accelerated decay in time/activity‐dependent plasticity and associative memory in an animal model of Alzheimer's diseaseNavakkode, Sheeja / Gaunt, Jessica Ruth / Pavon, Maria Vazquez / Bansal, Vibhavari Aysha / Abraham, Riya Prasad / Chong, Yee Song / Ch'ng, Toh Hean / Sajikumar, Sreedharan et al. | 2021
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Cisd2 slows down liver aging and attenuates age‐related metabolic dysfunction in male miceHuang, Yi‐Long / Shen, Zhao‐Qing / Huang, Chen‐Hua / Lin, Chao‐Hsiung / Tsai, Ting‐Fen et al. | 2021
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Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during agingDixit, Manisha / Duran‐Ortiz, Silvana / Yildirim, Godze / Poudel, Sher Bahadur / Louis, Leeann D. / Bartke, Andrzej / Schaffler, Mitchell B. / Kopchick, John J. / Yakar, Shoshana et al. | 2021
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Adiponectin alleviated Alzheimer‐like pathologies via autophagy‐lysosomal activationHe, Kaiwu / Nie, Lulin / Ali, Tahir / Wang, Shujin / Chen, Xiao / Liu, Zizhen / Li, Weifen / Zhang, Kaiqin / Xu, Jia / Liu, Jianjun et al. | 2021
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Mitochondrial aconitase 1 regulates age‐related memory impairment via autophagy/mitophagy‐mediated neural plasticity in middle‐aged fliesCho, Yun‐Ho / Kim, Gye‐Hyeong / Park, Joong‐Jean et al. | 2021
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Issue Information| 2021
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Selective oxidative stress induces dual damage to telomeres and mitochondria in human T cellsWang, Ling / Lu, Zeyuan / Zhao, Juan / Schank, Madison / Cao, Dechao / Dang, Xindi / Nguyen, Lam Nhat / Nguyen, Lam Ngoc Thao / Khanal, Sushant / Zhang, Jinyu et al. | 2021
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α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s diseaseTu, Hai‐Yue / Yuan, Bao‐Shi / Hou, Xiao‐Ou / Zhang, Xiao‐Jun / Pei, Chong‐Shuang / Ma, Ya‐Ting / Yang, Ya‐Ping / Fan, Yi / Qin, Zheng‐Hong / Liu, Chun‐Feng et al. | 2021
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α‐Synuclein antisense transcript SNCA‐AS1 regulates synapses‐ and aging‐related genes suggesting its implication in Parkinson's diseaseRey, Federica / Pandini, Cecilia / Messa, Letizia / Launi, Rossella / Barzaghini, Bianca / Zangaglia, Roberta / Raimondi, Manuela Teresa / Gagliardi, Stella / Cereda, Cristina / Zuccotti, Gian Vincenzo et al. | 2021
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Dietary citrate supplementation enhances longevity, metabolic health, and memory performance through promoting ketogenesisFan, Shou‐Zen / Lin, Cheng‐Sheng / Wei, Yu‐Wen / Yeh, Sheng‐Rong / Tsai, Yi‐Hsuan / Lee, Andrew Chengyu / Lin, Wei‐Sheng / Wang, Pei‐Yu et al. | 2021
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Phenotype correlations reveal the relationships of physiological systems underlying human ageingHao, Meng / Zhang, Hui / Hu, Zixin / Jiang, Xiaoyan / Song, Qi / Wang, Xi / Wang, Jiucun / Liu, Zuyun / Wang, Xiaofeng / Li, Yi et al. | 2021
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Non‐genomic rewiring of vitamin D receptor to p53 as a key to Alzheimer's diseaseLai, Rai‐Hua / Hsu, Yueh‐Ying / Shie, Feng‐Shiun / Huang, Che‐Ching / Chen, Mei‐Hsin / Juang, Jyh‐Lyh et al. | 2021
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Necroptosis contributes to chronic inflammation and fibrosis in aging liverMohammed, Sabira / Thadathil, Nidheesh / Selvarani, Ramasamy / Nicklas, Evan H. / Wang, Dawei / Miller, Benjamin F. / Richardson, Arlan / Deepa, Sathyaseelan S. et al. | 2021
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Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of agingZhang, Lei / Zhao, Jing / Mu, Xiaodong / McGowan, Sara J. / Angelini, Luise / O'Kelly, Ryan D. / Yousefzadeh, Matthew J. / Sakamoto, Ayumi / Aversa, Zaira / LeBrasseur, Nathan K. et al. | 2021
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Nogo receptor impairs the clearance of fibril amyloid‐β by microglia and accelerates Alzheimer’s‐like disease progressionWang, Jianing / Qin, Xiaoying / Sun, Hao / He, Meijun / Lv, Qunyu / Gao, Congcong / He, Xinran / Liao, Hong et al. | 2021
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miR‐125a‐5p increases cellular DNA damage of aging males and perturbs stage‐specific embryo development via Rbm38‐p53 signalingLiang, Kuan / Yao, Liangyu / Wang, Shuxian / Zheng, Lu / Qian, Zhang / Ge, Yifeng / Chen, Li / Cheng, Xi / Ma, Rujun / Li, Chuwei et al. | 2021
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Insights into T‐cell dysfunction in Alzheimer's diseaseDai, Linbin / Shen, Yong et al. | 2021