Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults (English)
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In:
Aging Cell
;
18
, 1
;
2019
- Article (Journal) / Electronic Resource
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Title:Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults
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Contributors:Konopka, Adam R. ( author ) / Laurin, Jaime L. ( author ) / Schoenberg, Hayden M. ( author ) / Reid, Justin J. ( author ) / Castor, William M. ( author ) / Wolff, Christopher A. ( author ) / Musci, Robert V. ( author ) / Safairad, Oscar D. ( author ) / Linden, Melissa A. ( author ) / Biela, Laurie M. ( author )
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Published in:Aging Cell ; 18, 1
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Publisher:
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Publication date:2019-02-01
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Size:12 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 18, Issue 1
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
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Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat dietKreienkamp, Ray / Billon, Cyrielle / Bedia‐Diaz, Gonzalo / Albert, Carolyn J. / Toth, Zacharie / Butler, Andrew A. / McBride‐Gagyi, Sara / Ford, David A. / Baldan, Angel / Burris, Thomas P. et al. | 2019
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A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signalingDworak, Natalia / Makosa, Dawid / Chatterjee, Mandovi / Jividen, Kasey / Yang, Chun‐Song / Snow, Chelsi / Simke, William C. / Johnson, Isaac G. / Kelley, Joshua B. / Paschal, Bryce M. et al. | 2019
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RanGAP‐mediated nucleocytoplasmic transport of Prospero regulates neural stem cell lifespan in Drosophila larval central brainWu, Di / Wu, Litao / An, Huanping / Bao, Hongcun / Guo, Pengfei / Zhang, Bei / Zheng, Huimei / Zhang, Fan / Ge, Wanzhong / Cai, Yu et al. | 2019
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Telomere length and telomerase activity in T cells are biomarkers of high‐performing centenariansTedone, Enzo / Huang, Ejun / O’Hara, Ryan / Batten, Kimberly / Ludlow, Andrew T. / Lai, Tsung‐Po / Arosio, Beatrice / Mari, Daniela / Wright, Woodring E. / Shay, Jerry W. et al. | 2019
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LncRNAs regulating stemness in agingSousa‐Franco, António / Rebelo, Kenny / da Rocha, Simão Teixeira / Bernardes de Jesus, Bruno et al. | 2019
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Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD miceBelfiore, Ramona / Rodin, Alexis / Ferreira, Eric / Velazquez, Ramon / Branca, Caterina / Caccamo, Antonella / Oddo, Salvatore et al. | 2019
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Carbon monoxide attenuates amyloidogenesis via down‐regulation of NF‐κB‐mediated BACE1 gene expressionKim, Hyo Jeong / Joe, Yeonsoo / Chen, Yingqing / Park, Gyu Hwan / Kim, Uh‐Hyun / Chung, Hun Taeg et al. | 2019
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Female XX sex chromosomes increase survival and extend lifespan in aging miceDavis, Emily J. / Lobach, Iryna / Dubal, Dena B. et al. | 2019
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Loss of PTEN induces lung fibrosis via alveolar epithelial cell senescence depending on NF‐κB activationTian, Yaqiong / Li, Hui / Qiu, Ting / Dai, Jinghong / Zhang, Yingwei / Chen, Jingyu / Cai, Hourong et al. | 2019
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Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adultsKonopka, Adam R. / Laurin, Jaime L. / Schoenberg, Hayden M. / Reid, Justin J. / Castor, William M. / Wolff, Christopher A. / Musci, Robert V. / Safairad, Oscar D. / Linden, Melissa A. / Biela, Laurie M. et al. | 2019
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Functional pathways regulated by microRNA networks in CD8 T‐cell agingGustafson, Claire E. / Cavanagh, Mary M. / Jin, Jun / Weyand, Cornelia M. / Goronzy, Jörg J. et al. | 2019
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Integrating cellular senescence with the concept of damage accumulation in aging: Relevance for clearance of senescent cellsOgrodnik, Mikolaj / Salmonowicz, Hanna / Gladyshev, Vadim N. et al. | 2019
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The bystander effect contributes to the accumulation of senescent cells in vivoda Silva, Paulo F. L. / Ogrodnik, Mikolaj / Kucheryavenko, Olena / Glibert, Julien / Miwa, Satomi / Cameron, Kerry / Ishaq, Abbas / Saretzki, Gabriele / Nagaraja‐Grellscheid, Sushma / Nelson, Glyn et al. | 2019
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Lymph nodes as barriers to T‐cell rejuvenation in aging mice and nonhuman primatesThompson, Heather L. / Smithey, Megan J. / Uhrlaub, Jennifer L. / Jeftić, Ilija / Jergović, Mladen / White, Sarah E. / Currier, Noreen / Lang, Anna M. / Okoye, Afam / Park, Byung et al. | 2019
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Independent associations of TOMM40 and APOE variants with body mass indexKulminski, Alexander M. / Loika, Yury / Culminskaya, Irina / Huang, Jian / Arbeev, Konstantin G. / Bagley, Olivia / Feitosa, Mary F. / Zmuda, Joseph M. / Christensen, Kaare / Yashin, Anatoliy I. et al. | 2019
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Senescent cells: A new Achilles’ heel to exploit for cancer medicine?Zhang, Boyi / Lam, Eric W.‐F. / Sun, Yu et al. | 2019
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Knockdown of heterochromatin protein 1 binding protein 3 recapitulates phenotypic, cellular, and molecular features of agingNeuner, Sarah M. / Ding, Shengyuan / Kaczorowski, Catherine C. et al. | 2019
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Issue Information| 2019
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Aging differentially modulates the Wnt pro‐survival signalling pathways in vascular smooth muscle cellsBrown, Bethan A. / Connolly, Georgia M. / Mill, Carina E. J. / Williams, Helen / Angelini, Gianni D. / Johnson, Jason L. / George, Sarah J. et al. | 2019
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Asymmetrical subcortical plasticity entails cognitive progression in older individualsEsteves, Madalena / Moreira, Pedro S. / Marques, Paulo / Castanho, Teresa C. / Magalhães, Ricardo / Amorim, Liliana / Portugal‐Nunes, Carlos / Soares, José M. / Coelho, Ana / Almeida, Armando et al. | 2019
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Disrupted‐in‐schizophrenia‐1 protects synaptic plasticity in a transgenic mouse model of Alzheimer’s disease as a mitophagy receptorWang, Zhao‐Tao / Lu, Mei‐Hong / Zhang, Yan / Ji, Wen‐Li / Lei, Lei / Wang, Wang / Fang, Li‐Pao / Wang, Lu‐Wen / Yu, Fan / Wang, Ji et al. | 2019
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MPK‐1/ERK is required for the full activity of resveratrol in extended lifespan and reproductionYoon, Dong Suk / Cha, Dong Seok / Choi, Yoorim / Lee, Jin Woo / Lee, Myon‐Hee et al. | 2019
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Amyloid β‐induced elevation of O‐GlcNAcylated c‐Fos promotes neuronal cell deathChoi, Heesun / Kim, Chaeyoung / Song, Hyundong / Cha, Moon‐Yong / Cho, Hyun Jin / Son, Sung Min / Kim, Haeng Jun / Mook‐Jung, Inhee et al. | 2019
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Autophagy and aging: Maintaining the proteome through exercise and caloric restrictionEscobar, Kurt A. / Cole, Nathan H. / Mermier, Christine M. / VanDusseldorp, Trisha A. et al. | 2019
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Trends in age‐related disease burden and healthcare utilizationAtella, Vincenzo / Piano Mortari, Andrea / Kopinska, Joanna / Belotti, Federico / Lapi, Francesco / Cricelli, Claudio / Fontana, Luigi et al. | 2019
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Partial reprogramming induces a steady decline in epigenetic age before loss of somatic identityOlova, Nelly / Simpson, Daniel J. / Marioni, Riccardo E. / Chandra, Tamir et al. | 2019
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Harnessing cellular aging in human stem cell models of amyotrophic lateral sclerosisZiff, Oliver J. / Patani, Rickie et al. | 2019
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Drosophilainsulin‐like peptide dilp1increases lifespan and glucagon‐like Akh expression epistatic to dilp2Post, Stephanie / Liao, Sifang / Yamamoto, Rochele / Veenstra, Jan A. / Nässel, Dick R. / Tatar, Marc et al. | 2019
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Epigenomic drivers of immune dysfunction in agingKeenan, Christine R. / Allan, Rhys S. et al. | 2019
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Cell‐free DNA as a biomarker of agingTeo, Yee Voan / Capri, Miriam / Morsiani, Cristina / Pizza, Grazia / Faria, Ana Maria Caetano / Franceschi, Claudio / Neretti, Nicola et al. | 2019
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Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulationTsakiri, Eleni N. / Gumeni, Sentiljana / Iliaki, Kalliopi K. / Benaki, Dimitra / Vougas, Konstantinos / Sykiotis, Gerasimos P. / Gorgoulis, Vassilis G. / Mikros, Emmanuel / Scorrano, Luca / Trougakos, Ioannis P. et al. | 2019
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Temporal pattern of neuronal insulin release during Caenorhabditis elegans aging: Role of redox homeostasisMinniti, Alicia N. / Arriagada, Héctor / Zúñiga, Soledad / Bravo‐Zehnder, Marcela / Alfaro, Iván E. / Aldunate, Rebeca et al. | 2019
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Reconciling nutritional geometry with classical dietary restriction: Effects of nutrient intake, not calories, on survival and reproductionMoatt, Joshua P. / Fyfe, Murray A. / Heap, Elizabeth / Mitchell, Luke J. M. / Moon, Fiona / Walling, Craig A. et al. | 2019
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Rapamycin improves healthspan but not inflammaging in nfκb1−/− miceCorreia‐Melo, Clara / Birch, Jodie / Fielder, Edward / Rahmatika, Dina / Taylor, Jennifer / Chapman, James / Lagnado, Anthony / Carroll, Bernadette M. / Miwa, Satomi / Richardson, Gavin et al. | 2019
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Programmed longevity, youthspan, and juventologyLongo, Valter D. et al. | 2019
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Nurr1 (NR4A2) regulates Alzheimer’s disease‐related pathogenesis and cognitive function in the 5XFAD mouse modelMoon, Minho / Jung, Eun Sun / Jeon, Seong Gak / Cha, Moon‐Yong / Jang, Yongwoo / Kim, Woori / Lopes, Claudia / Mook‐Jung, Inhee / Kim, Kwang‐Soo et al. | 2019
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Tau‐induced nuclear envelope invagination causes a toxic accumulation of mRNA in DrosophilaCornelison, Garrett L. / Levy, Simon A. / Jenson, Tyler / Frost, Bess et al. | 2019
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Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in miceNi, Junjun / Wu, Zhou / Stoka, Veronika / Meng, Jie / Hayashi, Yoshinori / Peters, Christoph / Qing, Hong / Turk, Vito / Nakanishi, Hiroshi et al. | 2019