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Engineering Cytochrome P450s for Enantioselective Cyclopropenation of Internal Alkynes
American Chemical Society | 2020| -
Enzymatic Primary Amination of Benzylic and Allylic C(sp3)–H Bonds
American Chemical Society | 2020| -
Directed Evolution of a Cytochrome P450 Carbene Transferase for Selective Functionalization of Cyclic Compounds
American Chemical Society | 2019| -
Enantiodivergent α‑Amino C–H Fluoroalkylation Catalyzed by Engineered Cytochrome P450s
American Chemical Society | 2019| -
Controlling Macromolecular Topology with Genetically Encoded SpyTag–SpyCatcher Chemistry
American Chemical Society | 2013| -
Enantioselective Total Synthesis of Nigelladine A via Late-Stage C–H Oxidation Enabled by an Engineered P450 Enzyme
American Chemical Society | 2017| -
Metal-Substituted Protein MRI Contrast Agents Engineered for Enhanced Relaxivity and Ligand Sensitivity
American Chemical Society | 2011| -
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
American Chemical Society | 2017| -
Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Ligands
American Chemical Society | 2019| -
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
American Chemical Society | 2018| -
Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation
American Chemical Society | 2019| -
Tryptophan Synthase Uses an Atypical Mechanism To Achieve Substrate Specificity
American Chemical Society | 2016| -
Regio- and Enantioselective Alkane Hydroxylation with Engineered Cytochromes P450 BM-3
American Chemical Society | 2003| -
High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution
American Chemical Society | 2020| -
Tryptophan Phosphorescence Study of Enzyme Flexibility and Unfolding in Laboratory-Evolved Thermostable Esterases †
American Chemical Society | 2000| -
Synthesis of β‑Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase
American Chemical Society | 2016| -
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
American Chemical Society | 2018| -
Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes
American Chemical Society | 2016| -
Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3
American Chemical Society | 2006|
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