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ADMET rules of thumb II: A comparison of the effects of common substituents on a range of ADMET parameters
Elsevier | 2009|Keywords: P450 inhibition -
AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
Free accessDOAJ | 2017|Keywords: cytochrome P450 inhibition -
Analytical approaches to determine cytochrome P450 inhibitory potential of new chemical entities in drug discovery
Elsevier | 2006|Keywords: In vitro cytochrome P450 inhibition assay -
An evaluation of the P450 inhibition and induction potential of daptomycin in primary human hepatocytes
Elsevier | 2004|Keywords: P450 inhibition -
Antimutagenicity of Flavones and Flavonols to Heterocyclic Amines by Specific and Strong Inhibition of the Cytochrome P450 1A Family
Free accessTaylor & Francis Verlag | 1998|Keywords: cytochrome P450 inhibition -
An update on metabolism studies using human hepatocytes in primary culture
Taylor & Francis Verlag | 2008|Keywords: P450 inhibition -
Assessment of Extracts from Mistletoe (Viscum album) for Herb–Drug Interaction by Inhibition and Induction of Cytochrome P450 Activities
Wiley | 2012|Keywords: cytochrome P450 inhibition -
Autoinhibitory properties of the parent but not of the N‐oxide metabolite contribute to infusion rate‐dependent voriconazole pharmacokinetics
Wiley | 2017|Keywords: cytochrome P450 inhibition -
Biotransformations of 6′,7′-dihydroxybergamottin and 6′,7′-epoxybergamottin by the citrus-pathogenic fungi diminish cytochrome P450 3A4 inhibitory activity
Elsevier | 2012|Keywords: Cytochrome P450 inhibition -
Cell Lines: A Tool for In Vitro Drug Metabolism Studies
Bentham Science Publishers | 2008|Keywords: P450 inhibition -
Corydaline Inhibits Multiple Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
Free accessDOAJ | 2011|Keywords: cytochrome P450 inhibition -
CYP2C8 and CYP3A4 are the principal enzymes involved in the human in vitro biotransformation of the insulin secretagogue repaglinide
Wiley | 2003|Keywords: cytochrome P450 inhibition -
CYP3A4 drug interactions: correlation of 10 in vitro probe substrates
Wiley | 1999|Keywords: cytochrome P450 inhibition -
CYPlebrity: Machine learning models for the prediction of inhibitors of cytochrome P450 enzymes
Elsevier | 2021|Keywords: Cytochrome P450 inhibition -
Cytochrome P450 Inhibition
Wiley | 2010|Keywords: cytochrome P450 inhibition ‐ drug accumulation effects -
Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439
Free accessAmerican Chemical Society | 2021|Keywords: cytochrome P450 inhibition -
Diagnosis of drug-induced liver injury in model mice by studying the inhibitory effect of serum components on P450 inhibition assay
Elsevier | 2022|Keywords: P450 inhibition assay -
Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes
Wiley | 1998|Keywords: cytochrome P450 inhibition -
Direct and metabolism‐dependent cytochrome P450 inhibition assays for evaluating drug–drug interactions
Wiley | 2013|Keywords: cytochrome P450 inhibition -
Discovery of a Potent and Short−Acting Oral Calcilytic with a Pulsatile Secretion of Parathyroid Hormone
American Chemical Society | 2011|Keywords: cytochrome P450 inhibition -
Dried Leaf Artemisia Annua Improves Bioavailability of Artemisinin via Cytochrome P450 Inhibition and Enhances Artemisinin Efficacy Downstream
Free accessDOAJ | 2020|Keywords: cytochrome p450 inhibition -
Effect of Honokiol on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
Free accessDOAJ | 2013|Keywords: cytochrome P450 inhibition -
Effects of Eupatilin and Jaceosidin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes
Free accessDOAJ | 2010|Keywords: cytochrome P450 inhibition -
Evaluation of coumarin-based fluorogenic P450 BM3 substrates and prospects for competitive inhibition screenings
Elsevier | 2014|Keywords: P450 inhibition -
Evaluation of Inhibitory Effects of Caffeic acid and Quercetin on Human Liver Cytochrome P450 Activities
Wiley | 2014|Keywords: cytochrome P450 inhibition -
Evaluation of in vitro cytochrome P450 induction and inhibition activity of deoxyelephantopin, a sesquiterpene lactone from Elephantopus scaber L.
Elsevier | 2013|Keywords: Cytochrome P450 inhibition assay -
Exploring the Possible Metabolism Mediated Interaction of Glycyrrhiza glabra Extract with CYP3A4 and CYP2D6
Wiley | 2011|Keywords: cytochrome P450 inhibition -
Hepatic cytochrome P450 inhibition by designer drugs and their metabolites
DataCite | 2015|Keywords: cytochrome P450 inhibition, Cytochrome P450 Inhibition -
Hepatic cytochrome P450 inhibition by designer drugs and their metabolites ; Hepatische Cytochrome P450 Inhibition durch Designer Drogen und deren Metaboliten
Free accessBASE | 2015|Keywords: Cytochrome P450 Inhibition -
Higher Throughput Human Hepatocyte Assays for the Evaluation of Time-Dependent Inhibition of CYP3A4
Bentham Science Publishers | 2011|Keywords: irreversible P450 inhibition -
Higher‐Throughput Screening Methods to Identify Cytochrome P450 Inhibitors and Inducers: Current Applications and Practice
Wiley | 2013|Keywords: cytochrome P450 inhibition -
Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
Elsevier | 2004|Keywords: Cytochrome P450 inhibition -
Inhibition of Cytochromes P450: Existing and New Promising Therapeutic Targets
Taylor & Francis Verlag | 2007|Keywords: P450 inhibition -
Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5′-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes
Free accessDOAJ | 2016|Keywords: time-dependent cytochrome P450 inhibition -
Inhibitory Effects of Dimethyllirioresinol, Epimagnolin A, Eudesmin, Fargesin, and Magnolin on Cytochrome P450 Enzyme Activities in Human Liver Microsomes
Free accessDOAJ | 2017|Keywords: cytochrome P450 inhibition -
Inhibitory Properties of Trapping Agents: Glutathione, Potassium Cyanide, and Methoxylamine, Against Major Human Cytochrome P450 Isoforms
Bentham Science Publishers | 2009|Keywords: P450 inhibition -
In vitro and in silico studies of interaction of synthetic 2,6,9-trisubstituted purine kinase inhibitors BPA-302, BP-21 and BP-117 with liver drug-metabolizing cytochromes P450
Free accessBASE|Keywords: cytochrome P450 inhibition -
In vitro drug–drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition
Taylor & Francis Verlag | 2008|Keywords: cytochrome P450 inhibition -
In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4
Taylor & Francis Verlag | 2011|Keywords: P450 inhibition -
In Vitro Screening of Metabolic Clearance Using Two Concentration Points
Bentham Science Publishers | 2010|Keywords: Potential P450 Inhibition -
Irreversible Cytochrome P450 Inhibition: Common Substructures and Implications for Drug Development
Wiley | 2008|Keywords: irreversible cytochrome P450 inhibition -
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development for screening of potential tamoxifen-drug/herb interaction via in vitro cytochrome P450 inhibition assay
Elsevier | 2020|Keywords: In vitro cytochrome P450 inhibition -
Mutations in Saccharomyces cerevisiae sterol C5-desaturase conferring resistance to the CYP51 inhibitor fluconazole
Elsevier | 2003|Keywords: Cytochrome P450 inhibition -
Novel functionalized 5-(phenoxymethyl)-1,3-dioxane analogs exhibiting cytochrome P450 inhibition: a patent evaluation WO2015048311 (A1)
Taylor & Francis Verlag | 2016|Keywords: P450 inhibition -
Pharmacokinetic, metabolic stability, plasma protein binding and CYP450s inhibition/induction assessment studies of N-(2-pyridylmethyl)-2-hydroxiymethyl-1-pyrrolidinyl-4-(3-chloro-4-methoxy-benzylamino)-5-pyrimidine-carboxamide as potential type 5 phosphodiesterase inhibitors
Free accessTaylor & Francis Verlag | 2019|Keywords: cytochrome p450 inhibition and induction -
Pharmacokinetic, metabolic stability, plasma protein binding and CYP450s inhibition/induction assessment studies of N-(2-pyridylmethyl)-2-hydroxiymethyl-1-pyrrolidinyl-4-(3-chloro-4-methoxy-benzylamino)-5-pyrimidine-carboxamide as potential type 5 phosphodiesterase inhibitors
Free accessDOAJ | 2019|Keywords: cytochrome p450 inhibition and induction -
Protein structure-based drug design: applications, limitations and future developments
Free accessSpringer Verlag | 2008|Keywords: P450 Inhibition -
Resistance to fluconazole and cross‐resistance to amphotericin B in Candida albicans from AIDS patients caused by defective sterol Δ5,6‐desaturation
Wiley | 1997|Keywords: P450 inhibition -
Structure and property based design of factor Xa inhibitors: Pyrrolidin-2-ones with aminoindane and phenylpyrrolidine P4 motifs
Elsevier | 2011|Keywords: P450 inhibition
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