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Decades-old renin inhibitors are still struggling to find a niche in antihypertensive therapy. A fleeting look at the old and the promising new molecules
Elsevier | 2020|Keywords: Renin angiotensin system, Renin inhibitors -
Effect of diuretics on plasma renin activity in primary hypertension: A systematic review and meta‐analysis
Wiley | 2021|Keywords: plasma renin activity, renin -
COX-2-derived $ PGE_{2} $ triggers hyperplastic renin expression and hyperreninemia in aldosterone synthase-deficient mice
Free accessOnline Contents | 2018|Keywords: Renin, Renin cell hyperplasia -
Recent progress on the discovery of non-peptidic direct renin inhibitors for the clinical management of hypertension
Taylor & Francis Verlag | 2013|Keywords: direct renin inhibitor, renin, renin–angiotensin–aldosterone system -
Pharmacokinetic, pharmacodynamic and clinical evaluation of aliskiren for hypertension treatment
Taylor & Francis Verlag | 2011|Keywords: plasma renin activity, renin, renin angiotensin system -
Regulation of the Renin—Angiotensin System Pathways in the Human Decidua
Online Contents | 2015|Keywords: renin–angiotensin system, renin -
Renin Activity in Heart Failure with Reduced Systolic Function—New Insights
Free accessDOAJ | 2019|Keywords: plasma renin activity, renin–angiotensin–aldosterone system, renin, (pro)renin receptor, direct renin inhibitor -
Salt feedback on the renin-angiotensin-aldosterone system
Online Contents | 2014|Keywords: Renin, Renin-angiotensin system -
(Pro)renin receptor antagonist PRO20 attenuates nephrectomy‐induced nephropathy in rats via inhibition of intrarenal RAS and Wnt/β‐catenin signaling
Free accessWiley | 2021|Keywords: renin‐angiotensin system, (Pro)renin receptor -
Salt feedback on the renin-angiotensin-aldosterone system
Online Contents | 2014|Keywords: Renin, Renin-angiotensin system -
Secretory and cytosolic (pro)renin in kidney, heart, and adrenal gland
Online Contents | 2008|Keywords: Renin sorting, Mitochondrial renin, Renin transgenic rats, Tissue renin–angiotensin systems -
Comparison of intrarenal renin‐angiotensin system activity in diabetic versus non‐diabetic patients with overt proteinuria
Wiley | 2015|Keywords: renin‐angiotensin system, renin -
The evolving landscape of RAAS inhibition: from ACE inhibitors to ARBs, to DRIs and beyond
Taylor & Francis Verlag | 2012|Keywords: direct renin inhibitor, plasma renin activity, (pro)renin receptor -
Direct Renin Inhibitor is Better than Angiotensin II Receptor Blocker for Intrarenal Arterioles
Free accessKarger Verlag | 2016|Keywords: Renin angiotensin system, Renin inhibitor -
Discovery of Novel 2‑Carbamoyl Morpholine Derivatives as Highly Potent and Orally Active Direct Renin Inhibitors
American Chemical Society | 2022|Keywords: Renin inhibitor, renin−angiotensin−aldosterone system -
An alternative renin isoform is cardioprotective by modulating mitochondrial metabolism
Free accessWiley | 2018|Keywords: exon(1A‐9)renin, exon‐b renin, cytosolic renin -
Angiotensin‐converting enzyme 2 in severe acute respiratory syndrome coronavirus and SARS‐CoV‐2: A double‐edged sword?
Wiley | 2020|Keywords: renin‐angiotensin system -
Design and optimization of new piperidines as renin inhibitors
Elsevier | 2010|Keywords: Renin–angiotensin–aldosterone system, Renin inhibitors
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