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Subject
Type of material
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Proposal and discussion of policy considerations for expansion of function claims to drive better consumer understanding of dietary supplement benefits in Japan (632.20)
Wiley | 2014|options for a regulatory framework for functional claims based on international trends and in response to recent decision of the Cabinet to ...Publisher: The Federation of American Societies for Experimental Biology -
Validation of cell‐based fluorescence assays: Practice guidelines from the ICSH and ICCS – part IV – postanalytic considerations
Wiley | 2013|International Council for Standardization of Haematology (ICSH) and International Clinical Cytometry Society (ICCS). Accordingly, a group of over 40 ... -
Validation of cell‐based fluorescence assays: Practice guidelines from the ICSH and ICCS – part I – rationale and aims
Wiley | 2013|International Council for Standardization of Haematology (ICSH) and International Clinical Cytometry Society (ICCS). Accordingly, a group of over 40 ... -
Residue Depletion Study of Danofloxacin in Cultured Tilapia (Oreochromis mossambicus)
Online Contents | 2015|Danofloxacin is an antibacterial drug of the fluoroquinolone group developed for therapeutic purposes in veterinary medicine. The studies ...Keywords: Drug Residues - analysis -
Exosome-mediated delivery and regulation in neurological disease progression
Elsevier | 2024|biological sources, have recently seized the attention of researchers due to their theranostic potential for neurological diseases. Released actively ...Keywords: Drug delivery -
Level 2 validation of a flow cytometric method for detection of Escherichia coli O157:H7 in raw spinach
Elsevier | 2015|used by the United States Food and Drug Administration (FDA) to detect Escherichia coli O157:H7 in spinach was systematically ... -
A comparison of molecular representations for lipophilicity quantitative structure–property relationships with results from the SAMPL6 logP Prediction Challenge
Springer Verlag | 2020|Effective representation of a molecule is required to develop useful quantitative structure–property
...Publisher: Springer International Publishing, Cham -
Dissecting biological activities of fibroblast growth factor receptors by the coiled-coil-mediated oligomerization of FGF1
Elsevier | 2021|membrane proteins involved in various biological processes including proliferation, migration and apoptosis. There are a number of regulatory ... -
Taking the individual bias out of examining comparability of biosimilars: A case study on monoclonal antibody therapeutics
Elsevier | 2022|translating to affordable biosimilars. Current practices for regulatory concurrence on analytical similarity data are based on chart visualization and ...Keywords: Electrospray ionization time-of-flight mass spectrometry, International Council for Harmonisationof Technical Requirements for Pharmaceuticals for Human Use, United States Food and Drug Administration -
An Update on Design and Pharmacology of Dendritic Poly(l-lysine)
Online Contents | 2018|in a new drug application category of various regulatory bodies. As dendritic poly(l-lysine) scaffold is biocompatible unlike many other ... -
A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy
Elsevier | 2021|drug resistance through both aerobic glycolysis and non-metabolic pathways. In this review, the functions and regulatory roles of PKM2 are ... -
Deuterated active pharmaceutical ingredients: A science‐based proposal for synthesis, analysis, and control. Part 1: Framing the problem
Wiley | 2019|chemistry, analytical chemistry, and drug metabolism and pharmacokinetics have been meeting under the auspices of IQ to define and address these ...Keywords: International Consortium for Innovation & Quality, drug substance -
Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole
Elsevier | 2015|because of its properties that inhibit glycolytic enzymes and detach them from the cytoskeleton. However, the broad effects of the drug, e.g ... -
8‐acetoxy‐trisulfopyrene as the first activatable fluorogenic probe for add‐and‐read assessment of Organic anion‐transporting polypeptides, OATP1B1, OATP1B3, and OATP2B1
Wiley | 2021|essential in drug development and is recommended by international regulatory agencies, the FDA, EMA, and PMDA. In general, radiolabeled indicators ...Keywords: drug interaction -
Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole
Online Contents | 2015|of CTZ because the drug does not affect the interaction of the PI3K regulatory subunit and the insulin receptor substrate (IRS)-1 ... -
Identification and characterization of a flexile G-quadruplex in the distal promoter region of stemness gene REX1
Elsevier | 2023|R1WT to be a promising drug target. The endogenous existence of R1WT was confirmed by BG4 antibody derived chromatin immunoprecipitation ... -
Mechanisms Underlying the Health Benefits of Plant Sterol and Stanol Ester Consumption
Online Contents | 2015|addition, they might influence the functioning of our immune system via a changed activity of the regulatory T-cells. This combination of effects ...Keywords: Immune System - drug effects -
To study percentage distribution of target genes encoding proteins of different classes in Helicobacter pylori strain J99 and identification of potential therapeutic targets to reduce its proliferation
Online Contents | 2015|plethora of potential drug targets. Subtractive study holds the promise of providing a conceptual framework for identification of potential drug ... -
The functions and mechanisms of post-translational modification in protein regulators of RNA methylation: Current status and future perspectives
Elsevier | 2023|. Despite advances in the structure and pharmacology of RNA methylation regulators that have improved drug discovery, regulating these proteins by ... -
Role of Metal-Organic Frameworks (MOFs) in treating and diagnosing microbial infections
Elsevier | 2024|Abstract This review article highlights the innovative role of metal ...
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