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Regulatory Concerns at Various Phases of Drug Development
British Library Conference Proceedings | 1998| -
Aspect of adhesives in transdermal drug delivery systems
Tema Archive | 2014|effective amount of drug across the skin. The quality attribute of the adhesives in TDDS is indispensible for fabrication design and important to ... -
Chitosan as a suitable nanocarrier material for anti-Alzheimer drug delivery
Online Contents | 2015|Chitosan, a biocompatible natural polysaccharide is frequently reported carrier material in targeted drug delivery to treat ...Keywords: Blood-Brain Barrier - drug effects, Drug Carriers - chemistry, Alzheimer Disease - drug therapy, Drug Carriers - therapeutic use -
Perspective on Advancing FDA Regulatory Monitoring for Mycotoxins in Foods using Liquid Chromatography and Mass Spectrometry (Review)
Online Contents | 2016|The presence of mycotoxins (such as aflatoxins, deoxynivalenol, fumonisins, and patulin) is routinely monitored by the U.S. Food and Drug ... -
Structural aspects of the interaction of anticancer drug Actinomycin-D to the GC rich region of hmgb1 gene
Online Contents | 2016|hmgb1 gene and selected a positive regulatory element of 25 base pair duplex (25RY) (-165 to -183) as a potential target for chemotherapeutic ... -
HPTLC Analysis of Venlafaxine Hydrochloride in the Bulk Drug and Tablets
Online Contents | 2010|validation in accordance with the requirements of pharmaceutical regulatory standards. The selectivity, accuracy, precision, and speed of the method ...Publisher: Springer International Publishing, Akadémiai Kiadó, Budapest -
Report on the tenth APCA government affairs seminar. Air quality: Status, management and direction
Tema Archive | 1982|. This meeting served as a forum for discussion of the issues of: the Clean Air Act amendments, regulatory reform, international perspectives on ... -
Single-Laboratory Validation of a Multitoxin Ultra-Performance LC-Hydrophilic Interaction LC-MS/MS Method for Quantitation of Paralytic Shellfish Toxins in Bivalve Shellfish
Online Contents | 2015|A single-laboratory validation study was conducted for the hydrophilic interaction-LC-MS/MS analysis of paralytic shellfish toxins (PSTs ...Keywords: Drug Residues - analysis -
Residue Depletion Study of Danofloxacin in Cultured Tilapia (Oreochromis mossambicus)
Online Contents | 2015|Danofloxacin is an antibacterial drug of the fluoroquinolone group developed for therapeutic purposes in veterinary medicine. The studies ...Keywords: Drug Residues - analysis -
Phosphatidylinositol-3-kinase as a putative target for anticancer action of clotrimazole
Online Contents | 2015|of CTZ because the drug does not affect the interaction of the PI3K regulatory subunit and the insulin receptor substrate (IRS)-1 ... -
Mechanisms Underlying the Health Benefits of Plant Sterol and Stanol Ester Consumption
Online Contents | 2015|addition, they might influence the functioning of our immune system via a changed activity of the regulatory T-cells. This combination of effects ...Keywords: Immune System - drug effects -
Trefoil Factor 1 is involved in gastric cell copper homeostasis
Online Contents | 2015|responsive elements present in the regulatory region of the gene. In addition we demonstrate that copper overload causes an accumulation of the ...Keywords: Protein Binding - drug effects, Transcription, Genetic - drug effects, Gene Expression Regulation - drug effects, trans-Golgi Network - drug effects, Protein Multimerization - drug effects, Cytoprotection - drug effects, Homeostasis - drug effects, Cell Survival - drug effects -
HILIC–MS Determination of Genotoxic Impurity of 2-Chloro-N-(2-Chloroethyl)Ethanamine in the Vortioxetine Manufacturing Process
Online Contents | 2016|In the last decade, pharmaceutical regulatory agencies are focused on monitoring and evaluation of trace-level genotoxic impurities (GTIs ... -
A Validated Stability-Indicating and Stereoselective HPLC Method for the Determination of Lenalidomide Enantiomers in Bulk Form and Capsules
Online Contents | 2016|International Conference on Harmonization/Food and Drug Administration regulatory requirements, was utilized successfully for the determination of LDM ... -
Energy metabolism disorders in rare and common diseases. Toward bioenergetic modulation therapy and the training of a new generation of European scientists
Online Contents | 2015|regulatory mechanisms discussed in this article. An excellent training of scientists in the field of energy metabolism, related human diseases and ... -
Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation
Online Contents | 2015|/V126L-MphR(A)–Ery complex. Our study gives useful insights into the nature of amino acids mutation effect, the mechanism of blocking drug ...Publisher: Springer International Publishing, Springer/ESCOM, Dordrecht -
Reference materials for USFDA's whole-body counting system
Online Contents | 1995|others. The new requirements of the Nuclear Regulatory Commission (NRC) include internal dose exposure, using such a system. The whole-body ...Keywords: International Atomic Energy Agency
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