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Synonyms were used for: barrier
Search without synonyms: keywords:(Avoidance of blood–brain barrier)
Used synonyms:
- barriere
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Fabrication and validation of an organ-on-chip system with integrated electrodes to directly quantify transendothelial electrical resistance
Free accessBASE | 2017|Keywords: Blood-brain barrier, Reproducibility of Results, Blood-Brain Barrier/cytology -
The connected steady state model and the interdependence of the CSF proteome and CSF flow characteristics
Free accessBASE | 2017|Keywords: blood-cerebrospinal fluid barrier, Autoimmune diseases of the nervous system, Blood-brain barrier -
Intravital two photon clcium imaging of glioblastoma mouse models
Free accessBASE | 2021|Keywords: Glioma is a brain tumor that derives from glial cells and it represents about 40% of all diagnosed central nervous system tumors. The most common type of glioma is glioblastoma multiforme (GBM), which is one of the most malignant tumors that can affect humans, with a median life expectancy of only 14 months. Its invasive properties and the presence of the blood-brain barrier makes GBM very hard to treat. Furthermore, GBM has a high degree of cellular and genetic heterogeneity, and the study of its genome is a very active field of research. As such, but there are no demonstrations in vivo of the correlation between GBM cell motility and calcium signaling. In light of this idea, we have modified the mouse glioma cell strain (GL261) to express a red fluorescent protein and a genetically encoded calcium sensor (GCaMP6s). Two photon imaging data that we acquired demonstrate that most of the tumor volume, we observed a novel phenomenon where groups of cells display synchronized (Ca2+)i waves propagating within the ensemble based on their common activation. Cells in these clusters/ensembles appear to have a direction-biased cellular motility. We postulate that tumor cells from peripheral regions and belonging to active clusters represent the infiltrating component of the tumor. Finally, by means of in utero electroporation, we transfected a small population of glial precursors with the active mutant of Ras (HRasV12) -
Assaying embryotoxicity in the test tube: Current limitations of the embryonic stem cell test (EST) challenging its applicability domain
Free accessBASE | 2012|Keywords: blood brain barrier, Predictive Value of Tests, Reproducibility of Results -
Drug-mediated toxicity: Illuminating the 'bad' in the test tube by means of cellular assays?
Free accessBASE | 2012|Keywords: blood brain barrier, OF-THE-ART
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