First evidence for the new tumor suppressor Pdcd4 as a regulator of u-PAR, an invasion-related gene (German)
- New search for: Leupold, J. H.
- New search for: Colburn, N. H.
- New search for: Yang, H.-S.
- New search for: Lengyel, E.
- New search for: Schildberg, F. W.
- New search for: Jauch, K.-W.
- New search for: Allgayer, H.
- New search for: Deutsche Gesellschaft fur Chirurgie
- New search for: Leupold, J. H.
- New search for: Colburn, N. H.
- New search for: Yang, H.-S.
- New search for: Lengyel, E.
- New search for: Schildberg, F. W.
- New search for: Jauch, K.-W.
- New search for: Allgayer, H.
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In:
Kongress der Deutschen Gesellschaft fur Chirurgie
120
;
69-72
;
2003
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ISBN:
- Conference paper / Print
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Title:First evidence for the new tumor suppressor Pdcd4 as a regulator of u-PAR, an invasion-related gene
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Contributors:Leupold, J. H. ( author ) / Colburn, N. H. ( author ) / Yang, H.-S. ( author ) / Lengyel, E. ( author ) / Schildberg, F. W. ( author ) / Jauch, K.-W. ( author ) / Allgayer, H. ( author ) / Haas, N. P. / Neugebauer, E. / Bauer, H.
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Conference:120, Kongress der Deutschen Gesellschaft fur Chirurgie ; 2003 ; Munich, Germany
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Published in:Kongress der Deutschen Gesellschaft fur Chirurgie , 120 ; 69-72
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Publisher:
- New search for: Springer
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Publication date:2003-01-01
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Size:4 pages
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Remarks:Text in German, some abstracts in English
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ISBN:
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Type of media:Conference paper
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Type of material:Print
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Language:German
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Keywords:
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Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents conference proceedings
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1
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The application of purified VP22 fusion proteins as a novel peptide-mediated and potential systemic therapy for pancreatic cancerBonicke, L. / Kang, C. / Pauls, R. / Tams, C. / Kurdow, R. / Schniewind, B. / Bohle, A. / Kremer, B. / Kalthoff, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 3
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Repopulation following hepatocellular transplantation - mechanisms of integration into the recipient liverKonig, S. / Stosser, C. / Krause, P. / Markus, P. M. / Becker, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 5
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The role of the cell type for the ex-vivo gene therapy to deliver bone morphogenic protein (BMP) in bone healingRose, T. / Peng, H. / Shen, H.-C. / Usas, A. / Josten, C. / Fu, F. H. / Huard, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 9
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Effect of soft tissue damage on fracture healing: intravital microscopic and biomechanical investigations in ratsSchaser, K. / Zhang, L. / Mittlmeier, T. / Ostapowicz, D. / Schmidmaier, G. / Duda, G. / Haas, N. P. / Bail, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 13
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Increased ubiquitination and degradation of activated caspase-3 in neutrophilic granulocytes under septic conditionsMica, L. / Harter, L. / Trentz, O. / Keel, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 17
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Three-dimensional computer tomographic evaluation of middle face growth following intrauterine repair of surgically created maxillary defects in the sheep fetusPapadopoulos, M. A. / Papadopulos, N. A. / Jannowitz, C. / Henke, J. / Bottcher, P. / Kloppel, M. / Muller, D. / Zeilhofer, H.-F. / Kovacs, L. / Biemer, E. et al. | 2003
- 21
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Serological definition of new tumour antigens of pancreatic carcinoma identified by high-density protein filterSoeth, E. / Romahn, O. / Bernstorff, W. v. / Tepel, J. / Kremer, B. / Kalthoff, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 25
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Human ductal pancreatic adenocarcinomas express high levels of protein kinase Cmu, a strong inducer of apoptosis resistance and cell proliferationTrauzold, A. / Sipos, B. / Schmiedel, S. / Westphal, S. / Roder, C. / Kalthoff, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 29
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HIF-1 regulates angioinvasion and metastasis by regulation of uPAR gene expression in pancreatic cancerBuchler, P. / Friess, H. / Muller, M. W. / Reber, H. A. / Hines, O. J. / Buchler, M. W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 33
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Interleukin-13: a mitogenic growth factor in pancreatic cancerProkopchuk, O. / Leder, G. / Kleeff, J. / Korc, M. / Kornmann, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 37
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The chemokines RANTES, KC and MCP-1 seem to play an important role in T-cell mediated tumor regressionSchmidt, J. / Hu, H. M. / Hatz, R. A. / Fox, B. A. / Schildberg, F. W. / van den Engel, N. K. / Winter, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 41
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Identification of specific nuclear matrix protein alterations in human colon polyps: a promising approach to early detection of colon cancerBrunagel, G. / Schoen, R. E. / Vietmeier, B. N. / Getzenberg, R. H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 45
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Microarray analysis in pancreatic cancer: identification of key genesFriess, H. / Kleeff, J. / Ding, J. / Korc, M. / Hammer, J. / Buchler, M. W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 47
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Expression analysis of microdissected pancreatic cancer and pancreatic cancer cell lines using DNA arraysGrutzmann, R. / Foerder, M. / Alldinger, I. / Ockert, D. / Li, X. / Brummendorf, T. / Staub, E. / Saeger, H. D. / Pilarsky, C. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 51
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A multigene expression panel for the molecular diagnosis of Barrett's esophagusBrabender, J. / Schneider, P. M. / Metzger, R. / Danenberg, K. D. / Danenberg, P. V. / Lord, R. V. / Marjoram, P. / Holscher, A. H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 55
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Proteomic analysis of colorectal carcinoma cell lines with different metastatic potential to induce liver metastasesVogel, I. / Heimbacher, L. / Wang, M. / Kremer, B. / Kalthoff, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 59
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Gain of chromosome 8q23-24 is a predictive marker for lymph node positivity in colorectal cancerGhadimi, B. M. / Grade, M. / Liersch, T. / Langer, C. / Siemer, A. / Fuzesi, L. / Becker, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 63
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Correlation of gene expression profiling and prognostic relevant parameters in colorectal cancerGrone, J. / Heinze, M. / Brummendorf, T. / Weber, B. / Klaman, I. / Hermann, K. / Buhr, H. J. / Mann, B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 65
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Interferon gamma enhances epithelial permeability by inducing reorganization of tight junction proteins from lateral membrane rafts independent of apoptosisBruwer, M. / Lugering, A. / Kucharzik, T. / Madara, J. L. / Hopkins, A. M. / Nusrat, A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 69
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First evidence for the new tumor suppressor Pdcd4 as a regulator of u-PAR, an invasion-related geneLeupold, J. H. / Colburn, N. H. / Yang, H.-S. / Lengyel, E. / Schildberg, F. W. / Jauch, K.-W. / Allgayer, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 73
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Cellular effects of irinotecan are p53 dependent in colorectal cancer cellsMann, B. / Bhonde, M. R. / Magrini, R. / Hanski, M. L. / Buhr, H. J. / Hanski, C. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 75
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Onyx 1520 and E4-deleted adenoviral constructs have comparable cytolytic efficiency independent of p53 status in colorectal cell linesCabrele, C. / Vogel, M. / Rentsch, M. / Furst, A. / Jauch, K. W. / Beham, A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 79
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Binding of gastrointestinal tumor cells to endothelial E- or P-selectin induces transient down-regulation of sLeX ligands in vitroMarkus, B. H. / Schleicher, D. / Mayer, G. / Leckel, K. / Bechstein, W. O. / Blaheta, R. A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 83
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Comparison of in-vivo cell adhesion of various colon carcinoma cell linesHaier, J. / Korb, T. / Schluter, K. / Spiegel, H. U. / Senninger, N. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 87
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Investigation of the angiogenic potency of disseminated tumor cells found in the bone marrow of patients with colorectal cancer: detection of the proliferation-associated Ki-67 antigen and the vascular endothelial growth factor (VEGF) in disseminated tumor cells detected in the bone marrow of patients suffering from colorectal cancerBucker, N. / Windhovel, U. / Bruch, H.-P. / Broll, R. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 91
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TGF beta-1 stimulates VEGF gene transcription in human cholangiocellular carcinomaBenckert, C. / Jonas, S. / Cramer, T. / Tullius, S. / Rosewicz, S. / Neuhaus, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 95
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Inhibition of tumor angiogenesis and vascular permeability by Angiopoietin-1Stoltzing, O. / Ahmad, S. A. / Liu, W. / McCarty, M. F. / Fan, F. / Bucana, C. D. / Ellis, L. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 99
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Latent antithrombin inhibits angiogenesis in A-Mel-3-Fortner melanoma by delay of capillary maturationLaschke, M. W. / Cengiz, Z. / Hoffmann, J. N. / Romisch, J. / Menger, M. D. / Vollmar, B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 103
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Complex three-dimensional in vitro model for analyzing mechanisms of immunosuppression of T cells in pancreatic cancervon Bernstorff, W. / Tams, C. / Kremer, B. / Kalthoff, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 105
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The role of HLA class I in the T-cell-induced immune response in human pancreatic carcinomaRyschich, E. / Autschbach, F. / Noetzel, T. / Hinz, U. / Klar, E. / Buchler, M. W. / Schmidt, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 109
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Tumor cell lysate-pulsed autologous dendritic cells induce a T-cell response in pancreatic cancerPeiper, M. / Sato, T. / Heinecke, A. / Eisenberger, C. / Knoefel, W. T. / Izbicki, J. R. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 111
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T-cell polarization (TH1/TH2) of lymphocytes from tumor vaccine-draining lymph nodes correlates with the immunogenicity of the tumorWinter, H. / Hu, H. M. / van den Engel, N. K. / Hatz, R. A. / Fox, B. A. / Schildberg, F. W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 115
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Regional immunotherapy after intraperitoneal inoculation of human gastric cancer cells in SCID mousePiso, P. / Aselmann, H. / Dahlke, M. H. / Klempnauer, J. / Schlitt, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 119
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Induction of active tumor immunity by intraperitoneal immunotherapy with trifunctional bispecific antibodies in gastric carcinoma and peritoneal carcinomatosisStrohlein, M. A. / Jager, M. / Lindhofer, H. / Jauch, K. W. / Heiss, M. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 123
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Does the detection of disseminated tumor cells in the liver of patients with colorectal cancer constitute a prognostic factor?Linnemann, U. / Schimanski, C. C. / Gebhardt, C. / Berger, M. R. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 127
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Detection of hematogenous tumor cell dissemination predicts tumor relapse in patients undergoing surgical resection of colorectal liver metastasesKoch, M. / Kienle, P. / Hinz, U. / Willeke, F. / Schmidt, J. / Herfarth, C. / von Knebel Doeberitz, M. / Weitz, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 131
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Prognostic relevance of disseminated tumor cells in blood and bone marrow in patients after neoadjuvant chemoradiation for rectal cancerKienle, P. / Koch, M. / Benner, A. / Treiber, M. / Wannemacher, M. / Lehnert, T. / von Knebel Doeberitz, M. / Herfarth, C. / Weitz, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 135
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Influence of telomere length and hTERT expression on progression and prognosis of colorectal carcinomaGertler, R. / Rosenberg, R. / Stricker, D. / Werner, M. / Nekarda, H. / Siewert, J. R. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 139
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Prognostic value of semiquantitative [^1^8F]FDG-PET in soft tissue sarcomaCardona, S. / Hinz, U. / Dimitrakopoulou-Strauss, A. / Mechtersheimer, G. / Buchler, M. W. / Lehnert, T. / Herfarth, C. / Schwarzbach, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 143
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Transcript co-expression of survivin and hTERT results in an extremely high risk of tumour-related death in soft tissue sarcoma patientsWurl, P. / Kappler, M. / Taubert, H. / Meye, A. / Bartel, F. / Kohler, T. / Henne-Bruns, D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 145
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Glivec (Imatinib) inhibits pancreatic cancer cell growth in vitro - a novel approach in the treatment of pancreatic cancer?Kleeff, J. / Fischer, L. / Esposito, I. / Bischoff, S. C. / Buchler, M. W. / Friess, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 149
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Effects of selective COX-2 and 5-LOX inhibition on liver metastasis and prostaglandin synthesis in ductal pancreatic cancer in syrian hamstersWenger, F. A. / Kilian, M. / Gregor, J. I. / Mautsch, I. / Schimke, I. / Guski, H. / Muller, J. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 153
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Suramin inhibits the proliferation of human pancreatic cancer in vitro and in vivoPorebski, A. / Hotz, H. G. / Hotz, B. / Buhr, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 157
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Blockade of the prostate stem cell antigen inhibits pancreatic cancer growthWente, M. N. / Jain, A. / Berberat, P. O. / Giese, T. / Reber, H. A. / Reiter, R. E. / Friess, H. / Buchler, M. W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 161
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Local application of phospholipids reduces peritoneal carcinosis by gastric cancer in an animal model and tumor cell adhesions to the extracellular matrix in vitroTreutner, K.-H. / Jansen, M. / Lynen-Jansen, P. / Weiss, C. / Tietze, L. / Bertram, P. / Zuber, S. / Schumpelick, V. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 165
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Hepatic arterial infusion (HAI) with liposomal taxol [^3H] in combination with degradable starch microspheres increases the concentration in CC-531 liver tumor of WAG ratsPohlen, U. / Berger, G. / Rieger, H. / Rezska, R. / Buhr, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 169
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Colorectal tumors and hepatic metastases differ in their optical properties - relevance for dosimetry in interstitial thermotherapyRoggan, A. / Ritz, J.-P. / Isbert, C. / Knappe, V. / Risk, J. / Buhr, H. J. / Germer, C.-T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 173
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In vivo evaluation of a simulation model for interstitial tumor ablation by radiofrequency in porcine liverRitz, J.-P. / Isbert, C. / Stein, T. / Roggan, A. / Lehmann, K. / Buhr, H. J. / Germer, C.-T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 175
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Impact of Pringle's manoeuvre during cryosurgery of porcine liver: strategy for reduction of cryotherapy-associated thrombocytopenia?Richter, S. / Kollmar, O. / Igna, D. / Menger, M. D. / Schilling, M. K. / Pistorius, G. A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 179
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Comparison of the local efficacy and pattern of metastases following resection, cryotherapy and laser therapy in a rat liver tumour model of colorectal cancerSeifert, J. K. / Becker, J. / Burg, J. / Dutkowski, P. / Junginger, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 183
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The role of bacterial permeation in ileoanal pouchLeistenschneider, P. / Kroesen, A. J. / Schulzke, J. D. / Fromm, M. / Buhr, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 187
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Possible interleukin-10 treatment for pouchitis in the ileoanal pouch after ulcerative colitisKroesen, A. J. / Giese, T. / Dullat, S. / Buhr, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 191
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Heme oxygenase-1 (HO-1)-generated biliverdin protects from colitisBerberat, P. O. / A-Rahim, Y. I. / Yamashita, K. / Warny, M. M. / Csizmadia, E. / Soares, M. P. / Robson, S. C. / Bach, F. H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 195
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Ultrastructural differences of the bowel wall in patients with diverticulosis and diverticulitis versus healthy controlsUlmer, T. F. / Willis, S. / Stumpf, M. / Rosch, R. / Fackeldey, V. / Schumpelick, V. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 199
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Influence of phospholipids and icodextrin on infection and adhesions in peritonitisMuller, S. A. / Treutner, K. H. / Haase, G. / Kinzel, S. / Tietze, L. / Schumpelick, V. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 203
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Surgical anatomy and neurophysiological parameters for identification and function testing of the pelvic autonomic nerves in patients undergoing TME for rectal cancerKneist, W. / Wolloscheck, T. / Konerding, M. A. / Junginger, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 207
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Low-level diode laser stimulates matrix protein synthesis of human chondrocytes in vitroJohn, T. / Shakibaei, M. / De Souza, P. / Schulze-Tanzil, G. / Ertel, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 209
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Healing of bone defects with mesenchymal precursor cells - does the osteogenic differentiation of the cells influence the healing of the defect?Frosch, K.-H. / Groll, C. / Dresing, K. / Sturmer, K. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 213
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Growth potential and differentiation status of human small hepatocytesLeckel, K. / El Makhfi, A. / Kratschell, R. / Markus, B. H. / Bechstein, W. O. / Blaheta, R. A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 215
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Glucose-regulated insulin expression following hepatic gene transferNett, P. C. / Sollinger, H. W. / Alam, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 217
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Bile duct reconstruction by in-vivo tissue engineering with venous implant and bio-absorbable stent in an animal modelHeistermann, H. P. / Palmes, D. / Hierlemann, H. / Schneiders, K. / Ebsen, M. / Hohlbach, G. / Spiegel, H. U. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 221
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Differentiation pattern of neuronal stem cells after transplantation into the traumatic injured brainRiess, P. / Laurer, H. / Zhang, C. / Schafer, U. / Maegele, M. / Bouillon, B. / Neugebauer, E. / McIntosh, T. K. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 225
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Tacrolimus impairs dermal but not intestinal wound healingSchaffer, M. / Fuchs, N. / Volker, J. / Viebahn, R. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 229
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Enhancement of impaired wound healing in an animal model by local inhibition of matrix metalloproteinase activitySafak, O. / Dagdelen, N. / Volkering, C. / Pfadenhauer, A. / Botzlar, A. / Sommerhoff, C. P. / Krell, H. W. / Mutschler, W. / Roesken, F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 233
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Increased cell proliferation and angiogenesis by controlled topical application of IGF-I for steroid-induced delayed wound healingBeckert, S. / Coerper, S. / Haack, S. / Hierlemann, H. / Becker, H. D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 237
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A new model to induce angiogenesis by ex vivo transfected isogenic fibroblasts based on gene transferMachens, H. G. / Spanholtz, T. / Maichle, A. / Niedworok, C. / Lindenmaier, W. / Herbort-Brand, S. / Gorg, S. / Kropf, K. / Stocklhuber, B. / Hellwig-Burgel, T. et al. | 2003
- 241
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Engineered adipose tissue supplied by functional microvessels: first step towards tissue engineering of complex, three-dimensional tissuesBorges, J. / Mueller, M. C. / Padron, N. T. / Tegtmeier, F. T. / Lang, E. M. / Stark, G. B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 243
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Full thickness skin regeneration by combination of an autologous keratinocyte-fibrin-glue-suspension and fibroblasts combined with acellular dermis - an experimental longterm study in a pig model: preliminary resultsFohn, M. / Knam, F. / Bannasch, H. / Horch, R. E. / Stark, G. B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 247
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Functional gene and protein analysis of neuroleukin expression in boneSommerfeldt, D. W. / Linhart, W. / Windolf, J. / Rueger, J. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 251
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Expression of metalloproteinases during murine fracture healing and their dependence on TNF-alphaLehmann, W. / Edgar, C. C. / Cho, T.-J. / Gerstenfeld, L. C. / Einhorn, T. A. / Rueger, J. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 255
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IGF-I and TGF-beta1 stimulate osteoblast differentiation but not proliferationWildemann, B. / Schmidmaier, G. / Lubberstedt, M. / Stange, R. / Haas, N. P. / Raschke, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 257
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Locally administered growth hormone and its mediator insulin-like growth factor exert similar effect on callus formation in a femur osteotomy model in ratsBail, H. / Huning, M. / Lindner, T. / Krummrey, G. / Flyvbjerg, A. / Raschke, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 261
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Identification of nanocolloidal particles in physiologic solution associated wear debris in different metal implant materialsTaeger, G. / Podleska, L. E. / Tikhovski, I. / Schmidt, B. / Fischer, A. / Ruchholtz, S. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 265
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A gentamicin coating of titanium implants for local prophylaxis of osteomyelitis - a rat modelLucke, M. / Schmidmaier, G. / Wildemann, B. / Sadoni, S. / Malzacher, H. / Schiller, R. / Raschke, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 269
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Lung contusion and the open lung concept - is computed tomography suitable for monitoring of lung recruitment?Stichert, B. / Schreiter, D. / Reske, A. / Seiwerts, M. / Josten, C. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 273
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Are circulating monocytes activated following blunt chest trauma?Liener, U. C. / Knoferl, M. W. / Perl, M. / Kurz, M. / Bruckner, U. B. / Kinzl, L. / Gebhard, F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 277
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An isolated lung contusion after blunt chest trauma results in systemic mediator release and Kupffer cell activationKnoferl, M. W. / Liener, U. C. / Perl, M. / Bruckner, U. B. / Kinzl, L. / Gebhard, F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 281
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Initial TNF-alpha and IL-8 mRNA expression in monocytes and neurological course of patients with severe traumatic brain injuryMussack, T. / Hauser, C. / Biberthaler, P. / Neth, P. / Mutschler, W. / Jochum, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 283
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CNS-targeted overexpression of the soluble complement inhibitor sCrry mediates improved blood-brain barrier function after experimental closed head injury in transgenic miceStahel, P. F. / Schmidt, O. I. / Rancan, M. / Morganti-Kossmann, M. C. / Saft, S. / Barnum, S. R. / Ertel, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 287
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Benefit of automatic crash notification (ACN): evaluation by analysis of severe motor vehicle accidentsPieske, O. / Lob, G. / Messner, G. / Lange, W. / Haberl, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 291
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Afferent intestinal sensitivity during postoperative ileus in mouse - a novel in vitro modelMueller, M. H. / Glatzle, J. / Kunze, W. / Becker, H.-D. / Grundy, D. / Kreis, M. E. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 295
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Visceral mediators released into mesenteric lymph during sepsis potently inhibit gastric, small intestinal, and colonic motility in ratsGlatzle, J. / Turck, H. M. / Wilhelm, W. / Muller, M. H. / Skirmuntt, C. / Raybould, H. E. / Becker, H. D. / Zittel, T. T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 299
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Endotoxin-mediated intestinal smooth muscle dysfunction following colonic surgeryTurler, A. / Moore, B. A. / Kalff, J. C. / Togel, S. / Hirner, A. / Bauer, A. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 303
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Dehydroepiandrosterone (DHEA) restores the suppressed PBMC function following major abdominal surgeryFrantz, M. C. / Wichmann, M. W. / Eisenmenger, S. J. / Angele, P. / Jauch, K. W. / Angele, M. K. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 307
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Modulation of TNF-alpha-induced inflammation by the p53-inhibitor pifithrin-alphaAmon, M. / Vollmar, B. / Menger, M. D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 311
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GM-CSF counteracts haemorrhage-induced suppression of cytokine-production capacityFlohe, S. / Husain, B. / Nast-Kolb, D. / Schade, F. U. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 315
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Molecular characterization of the acute septic response to Gram-positive versus Gram-negative bacterial infectionOberholzer, A. / Dinarello, C. A. / Ertel, W. / Moldawer, L. L. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 319
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IL-6 transduces protective effects of DHEA in polymicrobial sepsisvan Griensven, M. / Hildebrand, F. / Hoevel, P. / Muller, K. / Nitsche, N. / Krettek, C. / Pape, H.-C. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
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Immunomodulatory CpG-oligodeoxynucleotides reduce hepatocellular apoptosis and liver dysfunction during endotoxinemiaSlotta, J. E. / Menger, M. D. / Vollmar, B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 327
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Activated protein C during sepsis: cellular and microhemodynamic mechanisms of microcirculatory protectionHoffmann, J. N. / Vollmar, B. / Laschke, M. W. / Inthorn, D. / Schildberg, F. W. / Menger, M. D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 331
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Protective effect in the murine polymicrobial sepsis model by TLR2 agonist - induced cytokine modulationNovotny, A. R. / Kaiser-Moore, S. / Siewert, J.-R. / Holzmann, B. / Weighardt, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 335
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Protective function of NK1.1^+ cells in murine polymicrobial peritonitisMaier, S. / Entleutner, M. / Brummer, T. / Westerholt, A. / Heidecke, C. D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 337
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Evidence for naturally occurring in utero and oral tolerance to non-inherited maternal antigens (NIMA) in miceAndrassy, J. / Molitor, M. L. / Marthaler, B. R. / Geissler, E. K. / Jauch, K. W. / Sollinger, H.-W. / Burlingham, W. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 341
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Alloantigen-specific modulation of the immune response after transplantation using immunodominant peptidesTimmermann, W. / Sitaru, G. / Kottenmeier, S. / Gassel, H. J. / Ulrichs, K. / Otto, C. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 345
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Pegylated interferon alpha-2b plus ribavirin after OLT: Sustained virological response (SVR), clinical course and histologyBahra, M. / Neumann, U. P. / Berg, T. / Neuhaus, R. / Langrehr, J. M. / Neuhaus, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 349
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Effect of ischemia/reperfusion on the expression of p21^(^W^A^F^1^/^C^I^P^1^) and p27^(^K^i^p^1^) CDKI genes in concordant ex vivo hemoperfusion of primate kidneysGrosse, S. / Schelzig, H. / Chkhotua, A. B. / Abendroth, D. / Wiegand, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 353
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The influence of donor-specific class II MHC peptides on acute and chronic rejection after experimental kidney and small bowel transplantationGasser, M. / Lenhard, S. M. / Otto, C. / Timmermann, W. / Thiede, A. / Ulrichs, K. / Waaga-Gasser, A. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 357
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Results in human small bowel transplantationMuller, A. R. / Pascher, A. / Platz, K. P. / Schulz, R. J. / Dignass, A. / Radtke, C. / Neuhaus, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 361
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Quantification of brain death induced renal microperfusion disturbances in a porcine modelKorting, M. / Mehrabi, A. / Golling, M. / Hashemi, B. / Ahmadi, R. / Wiesel, M. / Buchler, M. W. / Klar, E. / Kraus, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 365
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Risk factor brain death - influence of induction of protective genes on graft functionPratschke, J. / Kordic, M. / Kotsch, K. / Pascher, A. / Tullius, S. G. / Volk, H. D. / Neuhaus, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 367
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The enhanced cellular immune response in old recipients accelerates chronic graft rejection in an experimental kidney transplant modelPascher, A. / Reutzel-Selke, A. / Bachmann, U. / Jurisch, A. / Pratschke, J. / Neuhaus, P. / Volk, H.-D. / Tullius, S. G. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 369
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Short-term immunosuppression of the donor prior to organ harvesting improves long-term graft functionSchmidbauer, G. / Pratschke, J. / Ulrich, F. / Reutzel-Selke, A. / Steinmuller, T. / Volk, H.-D. / Neuhaus, P. / Tullius, S. G. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 373
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Expression of T-cell attracting chemokines I-TAC, IP-10 and MIG in murine cardiac allografts is not influenced by cyclosporin-A treatmentBrandacher, G. / Schneeberger, S. / Ollinger, R. / Steurer, W. / Margreiter, R. / Werner, E. R. / Werner-Felmayer, G. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 377
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Influence of mycophenolate mofetil on graft vascular disease after aortic transplantation in a nonhuman primate modelKlupp, J. / Dambrin, C. / Hausen, B. / Birsan, T. / Luna, G. / Fitzgerald, P. / Berry, G. / Morris, R. E. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 381
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Arterial reconstruction in liver transplantation in the rat - comparison of different techniquesLehmann, T.-G. / Bunzendahl, H. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 385
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Orthotopic arterialized rat liver transplantation with telescoping stent technique of the supra- and infrahepatic vena cavaKrysiak, M. / Dutkowski, P. / Dunschede, F. / Junginger, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 389
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Comparison of two techniques of auxiliary, heterotopic rat liver transplantation by means of &unknown;OPS imaging&unknown;Schleimer, K. / Stippel, D. L. / Suer, C. / Tawadros, S. / Beckurts, K. T. E. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 393
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OPS imaging of the human hepatic microcirculation following full-size orthotopic liver transplantationPuhl, G. / Schaser, K.-D. / Pust, D. / Kohler, K. / Settmacher, U. / Neuhaus, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 397
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Platelet function and persisting thrombocytopenia following reperfusion are positively correlated with hepatocellular damage subsequent to orthotopic liver transplantation in childrenEsch, J. S. a. / Tustas, R. Y. / Akyildiz, A. / Ganschow, R. / Burdelski, M. / Fischer, L. / Broring, D. C. / Rogiers, X. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 401
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Sinusoidal overperfusion in reduced-size liver grafts: a potential mechanism for damage after liver resectionPalmes, D. / Budny, T. B. / Dietl, K. H. / Herbst, H. / Stratmann, U. / Spiegel, H. U. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 403
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Impact of intraischemic organ temperature on oxidative stress during hepatic reperfusionKhandoga, A. / Luchting, B. / Enders, G. / Axmann, S. / Biberthaler, P. / Krombach, F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 407
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Primary function of warm-ischemically damaged porcine kidneys after retrograde oxygen persufflation, hypothermic storage or machine perfusionPaul, A. / Treckmann, J. / Saad, S. / Hoffmann, J. / Fries, J. / Nagelschmidt, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 411
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Hypothermic oxygenated perfusion extracorporal (HOPE) of the rat liver: consequences for liver cell metabolism, release of reactive oxygen species and activation of apoptosisDutkowski, P. / Krug, A. / Dunschede, F. / Junginger, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 415
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Improvement of liver graft quality via inhibition of p53-dependent apoptosisEl-Gibaly, A. M. / Scheuer, C. / Menger, M. D. / Vollmar, B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 419
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Irreversible caspase 3 inhibition reduces apoptosis and improves survival after rat liver transplantationMueller, T. H. J. / Kienle, K. / Beham, A. / Engelhard, N. / Schwend, A. / Jauch, K.-W. / Geissler, E. K. / Anthuber, M. / Rentsch, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 423
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A caspase inhibitor significantly decreases apoptotic cell death in experimental pancreas transplantationDrognitz, O. / Liu, X. / Obermaier, R. / Neeff, H. / Hopt, U. T. / Benz, S. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 425
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Portal occlusion and liver function - evaluation of the rat model of portal branch ligationMuller, L. / Groteluschen, R. / Meyer, J. / Vashist, Y. K. / Abdulgawad, A. / Hillert, C. / Broring, D. C. / Rogiers, X. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 429
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Liver regeneration in FGF-2-deficient mice: functional and morphological aspectsKeese, M. / Bonninghoff, R. / Zhang, H. / Magdeburg, R. / Samel, S. / Hasenberg, T. / Sturm, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 433
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Blockade of RAGE promotes liver regeneration after massive hepatectomyCataldegirmen, G. / Yan, S. F. / Qu, W. / Lu, Y. / Broring, D. C. / Rogiers, X. / Stern, D. M. / Schmidt, A. M. / Emond, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 437
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Liver function after adenovirus-mediated gene-transfer of VEGF in a murine regeneration modelVashist, Y. K. / Redaelli, C. A. / Ledermann, M. / Kovac, J. / Sauter, B. / Dufour, J. F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 439
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Stem cell mobilization leads to induction of regeneration after subtotal liver resection and enables long-term survival in an otherwise lethal modelDahmen, U. / Dirsch, O. / Madrahimov, N. / Ji, Y. / Li, J. / Broelsch, C. E. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 441
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Embryonic stem cells prevent acute liver failure in retrorsine-treated rats - correlation with hepatic differentiation in vitroRuhnke, M. / Ungefroren, H. / Zehle, G. / Bader, B. / Kremer, B. / Fandrich, F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 445
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Increased apoptosis in the old mouse liver after ischemia and reperfusion - a novel pathway of injurySelzner, M. / Selzner, N. / Jochum, W. / Clavien, P.-A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 447
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NF-kappaB antisense blockade of liver sinusoidal endothelial cell (LSECs) improves microcirculation and reduces the reperfusion injury upon warm liver ischemia in the mouseBanafsche, R. / Schneider, M. / Knolle, P. A. / Klar, E. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 451
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Methylprednisolone minimizes hepatic ischemia-reperfusion injury through reduction of apoptosis and inflammation in ratsGlanemann, M. / Strenziok, R. / Munchow, S. / Langrehr, J. M. / Neuhaus, P. / Nuessler, A. K. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 455
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Glycine minimizes leukocyte - endothelium interaction after warm ischemia via mechanisms including inactivation of Kupffer cellsSchemmer, P. / Jost, J. / Conzelmann, L. O. / Poschl, U. / Mehrabi, A. / Gutt, C. / Gebhard, M.-M. / Buchler, M. W. / Klar, E. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 459
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alpha-Lipoic acid prevents ischemiareperfusion injury in rat liverDunschede, F. / Dutkowski, P. / Bittinger, F. / Junginger, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 463
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Induction of cellular resistance against Kupffer cell-derived oxidant stress: a novel concept of hepatoprotection by ischemic preconditioningSchauer, R. J. / Gerbes, A. L. / Vonier, D. / Winkel, M. o. d. / Fraunberger, P. / Messmer, K. / Bilzer, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 467
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A novel method for the intravital microscopic analysis of leukocyte transendothelial migration in vivoMoser, C. M. / Mempel, T. / Hutter, J. / Kubler, W. M. / Krombach, F. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 471
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Impact of immune suppressive drugs on postischemic microcirculation and leukocyte endothelium interactionSteinbauer, M. / Guba, M. / Frohlich, D. / Zulke, C. / Geissler, E. K. / Anthuber, M. / Jauch, K.-W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 473
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VIP improves renal perfusion and ameliorates mucosal damage following intestinal ischemia and reperfusionLeister, I. / Gutt, C. N. / Becker, H. / Markus, P. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 477
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NF-kappa B-mediated NOS-2 expression is protective after intestinal ischemiaNussler, N. C. / Muller, A. R. / Neuhaus, P. / Nussler, A. K. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 481
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Epigallocatechin gallate can significantly decrease oxygen free radicals in reperfusion injury in vivoPhilipp, A. W. / Schlenzka, L. / Mall, J. W. / Buttemeyer, R. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 485
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Antioxidative ebselen inhibits platelet CD62P expression and functions antithrombotic in vivoLindenblatt, N. / Schareck, W. / Belusa, L. / Nickels, R. M. / Menger, M. D. / Vollmar, B. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 487
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Near-infrared reflectance confocal microscopy: a new method to evaluate pancreatic microcirculation in experimental acute pancreatitisKeck, T. / Warshaw, A. L. / Alsfasser, G. / Antoniu, B. / Gonzales, S. / Castillo, C. F.-d. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 491
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Platelet function in ischemia-reperfusion-induced acute pancreatitisHackert, T. / Werner, J. / Hartwig, W. / Pfeil, D. / Gebhard, M. / Buchler, M. W. / Uhl, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 495
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Lung injury is more severe in alcoholic than in biliary pancreatitis in rats: role of liver microcirculation and systemic cytokine releaseWerner, J. / Pietschmann, M. / Hartwig, W. / Hackert, T. / Strobel, O. / Muller, C. / Gebhard, M. M. / Buchler, M. W. / Uhl, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 499
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Ischemic preconditioning of the pancreasWiessner, R. / Foitzik, T. / Benz, S. / Schareck, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 503
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The negative effects of esmolol in the treatment of hemodynamic response to capnoperitoneumJunghans, T. / Bohm, B. / Modersohn, D. / Schwenk, W. / Neuss, H. / Dorner, F. / Haase, O. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 505
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Influence of gases used for laparoscopy (CO~2, helium) on proliferation and apoptosis of a malign liver tumor in ratDahn, S. / Schwalbach, P. / Wohleke, F. / Benner, A. / Kuntz, C. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 509
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Polypropylene mesh repair for treatment of groin hernias induces a B7-2 (CD86)-positive fasciitis in ratsIsbert, C. / Wittkowski, T. / Ritz, J.-P. / Buhr, H. J. / Germer, C.-T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 513
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Development and evaluation of a training module for the clinical introduction of the Da Vinci robotic systemMehrabi, A. / Gutt, C. / Yetimoglu, C. L. / Kienle, P. / Schemmer, P. / Friess, H. / Schmidt, J. / Buchler, M. W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 517
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The status quo of the case - control study in the surgical literatureSauerland, S. / Lefering, R. / Jahn, S. / Neugebauer, E. A. M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 519
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Laparoscopic versus open inguinal hernioplasty: all questions solved by meta-analysis?Stengel, D. / Bauwens, K. / Ekkernkamp, A. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 523
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Quality of life assessment in colorectal surgery: influence of clinical risk profiles on patient compliance and interpretation of resultsKopp, I. / Lorenz, W. / Stinner, B. / Koller, M. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 527
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High acceptance of additive perioperative psychological interventions despite lack of effect on pain perception after colorectal resection - a randomized, partially blinded trialHaase, O. / Hermann, C. / Muller, J. M. / Schwenk, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 531
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A randomized prospective intervention study on the impact of psychooncological support for surgical inpatients with colorectal cancerDetermann, M. M. / Kollenbaum, V.-E. / Kremer, B. / Henne-Bruns, D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 535
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Coloplasty vs. colonic J-pouch following resection of distal rectal cancer - results of a prospective randomized pilot studyFurst, A. / Suttner, S. / Agha, A. / Beham, A. / Jauch, K.-W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 541
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Local hemodynamics and energy losses of crural anastomoses: in-vitro study using particle image velocimetryHeise, M. / Kruger, U. / Ruckert, R. / Rosler, S. / Neuhaus, P. / Settmacher, U. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 545
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Small type 1 endoleaks in abdominal aortic aneurysm with stent graft lead to systemic pressure in the aneurysmal sac - an in-vitro studyKnez, P. / Menges, D. / Ritter, R. / Silber, G. / Benderoth, G. / Schmitz-Rixen, T. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 549
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Genomic analysis of the matrix metalloproteinase-2 gene (MMP-2) as a potential etiologic factor of spontaneous aortic aneurysmsHinterseher, I. / Krex, D. / Ockert, D. / Kuhlisch, E. / Schackert, H. K. / Saeger, H. D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 551
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A possible therapy with HIV-1-Tat-derived peptides for the treatment of unreconstructable end-stage vascular diseasesIsmail, M. / Braumann, C. / Ruckert, R. I. / Dubiel, W. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 553
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Endotension and compliance of the aneurysm wall - an in vitro studyGawenda, M. / Knez, P. / Jaschke, G. / Winter, S. / Schmitz-Rixen, T. / Brunkwall, J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 557
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Evidence of lack of contact inhibition in the liver by northern blot and array technique in congenital diaphragmatic hernia in a nitrofen rat modelLangwieler, T. E. / Mann, O. / Izbicki, J. R. / Lambrecht, W. / Kluth, D. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 561
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Endocrine secretion and physiological responsiveness of human parathyroid tissue after microencapsulation with sodium cellulose sulphate and Poly-DADMACUlrich, F. / Steinmuller, T. / Gartner, M. / Tullius, S. G. / Kamm, B. / Muller, C. / Neuhaus, P. / Deutsche Gesellschaft fur Chirurgie et al. | 2003
- 565
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Unilateral microembolization of the lung: an in vivo videomicroscopic study of the pulmonary microcirculation in the ratSchneider, P. / Schneider, M.-P. / Buhr, H. J. / Deutsche Gesellschaft fur Chirurgie et al. | 2003