Analysis of Binding Sites for the New Small-Molecule CCR5 Antagonist TAK-220 on Human CCR5 (English)
- New search for: Nishikawa, M.
- New search for: Takashima, K.
- New search for: Nishi, T.
- New search for: Furuta, R. A.
- New search for: Kanzaki, N.
- New search for: Yamamoto, Y.
- New search for: Fujisawa, J.-i.
- New search for: Nishikawa, M.
- New search for: Takashima, K.
- New search for: Nishi, T.
- New search for: Furuta, R. A.
- New search for: Kanzaki, N.
- New search for: Yamamoto, Y.
- New search for: Fujisawa, J.-i.
In:
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY -JOURNAL-
;
49
, 11
;
4708-4715
;
2005
-
ISSN:
- Article (Journal) / Print
-
Title:Analysis of Binding Sites for the New Small-Molecule CCR5 Antagonist TAK-220 on Human CCR5
-
Contributors:Nishikawa, M. ( author ) / Takashima, K. ( author ) / Nishi, T. ( author ) / Furuta, R. A. ( author ) / Kanzaki, N. ( author ) / Yamamoto, Y. ( author ) / Fujisawa, J.-i. ( author )
-
Published in:ANTIMICROBIAL AGENTS AND CHEMOTHERAPY -JOURNAL- ; 49, 11 ; 4708-4715
-
Publisher:
- New search for: AMERICAN SOCIETY FOR MICROBIOLOGY
-
Publication date:2005-01-01
-
Size:8 pages
-
ISSN:
-
Type of media:Article (Journal)
-
Type of material:Print
-
Language:English
- New search for: 615.329 / 615
- Further information on Dewey Decimal Classification
-
Classification:
-
Source:
© Metadata Copyright the British Library Board and other contributors. All rights reserved.
Table of contents – Volume 49, Issue 11
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 4429
-
Population Pharmacokinetics of Rifapentine and Its Primary Desacetyl Metabolite in South African Tuberculosis PatientsLangdon, G. / Wilkins, J. / McFadyen, L. / McIlleron, H. / Smith, P. / Simonsson, U. S. H. et al. | 2005
- 4437
-
Application of Quantitative Real-Time Reverse Transcription-PCR in Assessing Drug Efficacy against the Intracellular Pathogen Cryptosporidium parvum In VitroCai, X. / Woods, K. M. / Upton, S. J. / Zhu, G. et al. | 2005
- 4443
-
TEM-109 (CMT-5), a Natural Complex Mutant of TEM-1 beta-Lactamase Combining the Amino Acid Substitutions of TEM-6 and TEM-33 (IRT-5)Robin, F. / Delmas, J. / Chanal, C. / Sirot, D. / Sirot, J. / Bonnet, R. et al. | 2005
- 4448
-
Antibiotic Abscess Penetration: Fosfomycin Levels Measured in Pus and Simulated Concentration-Time ProfilesSauermann, R. / Karch, R. / Langenberger, H. / Kettenbach, J. / Mayer-Helm, B. / Petsch, M. / Wagner, C. / Sautner, T. / Gattringer, R. / Karanikas, G. et al. | 2005
- 4455
-
Fitness Cost Due to Mutations in the 16S rRNA Associated with Spectinomycin Resistance in Chlamydia psittaci 6BCBinet, R. / Maurelli, A. T. et al. | 2005
- 4465
-
Anti-Human Immunodeficiency Virus Type 1 Activity of the Nonnucleoside Reverse Transcriptase Inhibitor GW678248 in Combination with Other Antiretrovirals against Clinical Isolate Viruses and In Vitro Selection for ResistanceHazen, R. J. / Harvey, R. J. / StClair, M. H. / Ferris, R. G. / Freeman, G. A. / Tidwell, J. H. / Schaller, L. T. / Cowan, J. R. / Short, S. A. / Romines, K. R. et al. | 2005
- 4474
-
Photodynamic Sensitization of Leishmania amazonensis in both Extracellular and Intracellular Stages with Aluminum Phthalocyanine Chloride for Photolysis In VitroDutta, S. / Ray, D. / Kolli, B. K. / Chang, K.-P. et al. | 2005
- 4485
-
Novel Acquired Metallo-beta-Lactamase Gene, bla~S~I~M~-~1, in a Class 1 Integron from Acinetobacter baumannii Clinical Isolates from KoreaLee, K. / Yum, J. H. / Yong, D. / Lee, H. M. / Kim, H. D. / Docquier, J.-D. / Rossolini, G. M. / Chong, Y. et al. | 2005
- 4492
-
Relationship of Pleconaril Susceptibility and Clinical Outcomes in Treatment of Common Colds Caused by RhinovirusesPevear, D. C. / Hayden, F. G. / Demenczuk, T. M. / Barone, L. R. / McKinlay, M. A. / Collett, M. S. et al. | 2005
- 4500
-
Identification of a Dithiazoline Inhibitor of Escherichia coli L,D-Carboxypeptidase ABaum, E. Z. / Crespo-Carbone, S. M. / Foleno, B. / Peng, S. / Hilliard, J. J. / Abbanat, D. / Goldschmidt, R. / Bush, K. et al. | 2005
- 4508
-
Randomized, Placebo-Controlled Trial of Nonpegylated and Pegylated Forms of Recombinant Human Alpha Interferon 2a for Suppression of Dengue Virus Viremia in Rhesus MonkeysAjariyakhajorn, C. / Mammen, M. P. / Endy, T. P. / Gettayacamin, M. / Nisalak, A. / Nimmannitya, S. / Libraty, D. H. et al. | 2005
- 4515
-
Susceptibilities of Antiviral-Resistant Influenza Viruses to Novel Neuraminidase InhibitorsMishin, V. P. / Hayden, F. G. / Gubareva, L. V. et al. | 2005
- 4521
-
Use of Ribotyping To Retrospectively Identify Methicillin-Resistant Staphylococcus aureus Isolates from Phase 3 Clinical Trials for Tigecycline That Are Genotypically Related to Community-Associated IsolatesMcAleese, F. / Murphy, E. / Babinchak, T. / Singh, G. / Said-Salim, B. / Kreiswirth, B. / Dunman, P. / O Connell, J. / Projan, S. J. / Bradford, P. A. et al. | 2005
- 4530
-
Evaluation of Antibiotic Treatment against "Candidatus Helicobacter suis" in a Mouse ModelHellemans, A. / Decostere, A. / Haesebrouck, F. / Ducatelle, R. et al. | 2005
- 4536
-
Pharmacokinetics, Safety, and Tolerability of Caspofungin in Children and AdolescentsWalsh, T. J. / Adamson, P. C. / Seibel, N. L. / Flynn, P. M. / Neely, M. N. / Schwartz, C. / Shad, A. / Kaplan, S. L. / Roden, M. M. / Stone, J. A. et al. | 2005
- 4546
-
High Potency of Indolyl Aryl Sulfone Nonnucleoside Inhibitors towards Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutants Is Due to Selective Targeting of Different Mechanistic Forms of the EnzymeCancio, R. / Silvestri, R. / Ragno, R. / Artico, M. / De Martino, G. / La Regina, G. / Crespan, E. / Zanoli, S. / Hubscher, U. / Spadari, S. et al. | 2005
- 4555
-
Prior Antimicrobial Therapy and Risk for Hospital-Acquired Candida glabrata and Candida krusei Fungemia: a Case-Case-Control StudyLin, M. Y. / Carmeli, Y. / Zumsteg, J. / Flores, E. L. / Tolentino, J. / Sreeramoju, P. / Weber, S. G. et al. | 2005
- 4561
-
Antibacterial Activity of Human Neutrophil Defensin HNP-1 Analogs without CysteinesVarkey, J. / Nagaraj, R. et al. | 2005
- 4567
-
Pseudomonas aeruginosa AmpR Is a Global Transcriptional Factor That Regulates Expression of AmpC and PoxB beta-Lactamase, Proteases, Quorum Sensing, and Other Virulence FactorsKong, K.-F. / Jayawardena, S. R. / Indulkar, S. D. / del Puerto, A. / Koh, C.-L. / Hoiby, N. / Mathee, K. et al. | 2005
- 4576
-
Nystatin Biosynthesis and Transport: nysH and nysG Genes Encoding a Putative ABC Transporter System in Streptomyces noursei ATCC 11455 Are Required for Efficient Conversion of 10-Deoxynystatin to NystatinSletta, H. / Borgos, S. E. F. / Bruheim, P. / Sekurova, O. N. / Grasdalen, H. / Aune, R. / Ellingsen, T. E. / Zotchev, S. B. et al. | 2005
- 4584
-
TAK-652 Inhibits CCR5-Mediated Human Immunodeficiency Virus Type 1 Infection In Vitro and Has Favorable Pharmacokinetics in HumansBaba, M. / Takashima, K. / Miyake, H. / Kanzaki, N. / Teshima, K. / Wang, X. / Shiraishi, M. / Iizawa, Y. et al. | 2005
- 4592
-
In Vitro Assessment of Methylene Blue on Chloroquine-Sensitive and -Resistant Plasmodium falciparum Strains Reveals Synergistic Action with ArtemisininsAkoachere, M. / Buchholz, K. / Fischer, E. / Burhenne, J. / Haefeli, W. E. / Schirmer, R. H. / Becker, K. et al. | 2005
- 4598
-
Phosphinothricin Tripeptide Synthetases in Streptomyces viridochromogenes Tu494Schwartz, D. / Grammel, N. / Heinzelmann, E. / Keller, U. / Wohlleben, W. et al. | 2005
- 4608
-
Mechanisms of Azole Resistance in a Clinical Isolate of Candida tropicalisVandeputte, P. / Larcher, G. / Berges, T. / Renier, G. / Chabasse, D. / Bouchara, J.-P. et al. | 2005
- 4616
-
Gene Expression Analysis of the Mechanism of Natural Sb(V) Resistance in Leishmania donovani Isolates from NepalDecuypere, S. / Rijal, S. / Yardley, V. / De Doncker, S. / Laurent, T. / Khanal, B. / Chappuis, F. / Dujardin, J.-C. et al. | 2005
- 4622
-
Amino Acid Mutations Essential to Production of an Altered PBP 2X Conferring High-Level beta-Lactam Resistance in a Clinical Isolate of Streptococcus pneumoniaeSmith, A. M. / Klugman, K. P. et al. | 2005
- 4628
-
Inhibitory Activities of Epidermal Growth Factor Receptor Tyrosine Kinase-Targeted Dihydroxyisoflavone and Trihydroxydeoxybenzoin Derivatives on Sarcocystis neurona, Neospora caninum, and Cryptosporidium parvum DevelopmentGargala, G. / Baishanbo, A. / Favennec, L. / Francois, A. / Ballet, J. J. / Rossignol, J.-F. et al. | 2005
- 4635
-
Expression of the mef(E) Gene Encoding the Macrolide Efflux Pump Protein Increases in Streptococcus pneumoniae with Increasing Resistance to MacrolidesWierzbowski, A. K. / Boyd, D. / Mulvey, M. / Hoban, D. J. / Zhanel, G. G. et al. | 2005
- 4641
-
Horizontal Transfer of Iturin A Operon, itu, to Bacillus subtilis 168 and Conversion into an Iturin A ProducerTsuge, K. / Inoue, S. / Ano, T. / Itaya, M. / Shoda, M. et al. | 2005
- 4649
-
A Class of Pantothenic Acid Analogs Inhibits Plasmodium falciparum Pantothenate Kinase and Represses the Proliferation of Malaria ParasitesSpry, C. / Chai, C. L. L. / Kirk, K. / Saliba, K. J. et al. | 2005
- 4658
-
Safety and Efficacy of Tigecycline in Treatment of Skin and Skin Structure Infections: Results of a Double-Blind Phase 3 Comparison Study with Vancomycin-AztreonamBreedt, J. / Teras, J. / Gardovskis, J. / Maritz, F. J. / Vaasna, T. / Ross, D. P. / Gioud-Paquet, M. / Dartois, N. / Ellis-Grosse, E. J. / Loh, E. et al. | 2005
- 4667
-
Virulence Factors of Escherichia coli Isolates That Produce CTX-M-Type Extended-Spectrum beta-LactamasesPitout, J. D. D. / Laupland, K. B. / Church, D. L. / Menard, M. L. / Johnson, J. R. et al. | 2005
- 4671
-
Organotypic Epithelial Raft Cultures as a Model for Evaluating Compounds against AlphaherpesvirusesAndrei, G. / van den Oord, J. / Fiten, P. / Opdenakker, G. / De Wolf-Peeters, C. / De Clercq, E. / Snoeck, R. et al. | 2005
- 4681
-
DNA Sequence and Comparative Genomics of pAPEC-O2-R, an Avian Pathogenic Escherichia coli Transmissible R PlasmidJohnson, T. J. / Siek, K. E. / Johnson, S. J. / Nolan, L. K. et al. | 2005
- 4689
-
Mouse Adenovirus Type 1 Infection in SCID Mice: an Experimental Model for Antiviral Therapy of Systemic Adenovirus InfectionsLenaerts, L. / Verbeken, E. / De Clercq, E. / Naesens, L. et al. | 2005
- 4700
-
Comparative Effects of Two Neutralizing Anti-Respiratory Syncytial Virus (RSV) Monoclonal Antibodies in the RSV Murine Model: Time versus PotencyMejias, A. / Chavez-Bueno, S. / Rios, A. M. / Aten, M. F. / Raynor, B. / Peromingo, E. / Soni, P. / Olsen, K. D. / Kiener, P. A. / Gomez, A. M. et al. | 2005
- 4708
-
Analysis of Binding Sites for the New Small-Molecule CCR5 Antagonist TAK-220 on Human CCR5Nishikawa, M. / Takashima, K. / Nishi, T. / Furuta, R. A. / Kanzaki, N. / Yamamoto, Y. / Fujisawa, J.-i. et al. | 2005
- 4716
-
Molecular Analysis of the Simultaneous Production of Two SHV-Type Extended-Spectrum Beta-Lactamases in a Clinical Isolate of Enterobacter cloacae by Using Single-Nucleotide Polymorphism GenotypingSzabo, D. / Melan, M. A. / Hujer, A. M. / Bonomo, R. A. / Hujer, K. M. / Bethel, C. R. / Kristof, K. / Paterson, D. L. et al. | 2005
- 4721
-
Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 ActivityDorr, P. / Westby, M. / Dobbs, S. / Griffin, P. / Irvine, B. / Macartney, M. / Mori, J. / Rickett, G. / Smith-Burchnell, C. / Napier, C. et al. | 2005
- 4733
-
Molecular Mechanisms of beta-Lactam Resistance Mediated by AmpC Hyperproduction in Pseudomonas aeruginosa Clinical StrainsJuan, C. / Macia, M. D. / Gutierrez, O. / Vidal, C. / Perez, J. L. / Oliver, A. et al. | 2005
- 4739
-
Spontaneous Conversion to Quinolone and Fluoroquinolone Resistance among Wild-Type Escherichia coli Isolates in Relation to Phylogenetic Background and Virulence GenotypeJohnson, J. R. / Johnston, B. / Kuskowski, M. A. / Colodner, R. / Raz, R. et al. | 2005
- 4745
-
CTX-M-2 and a New CTX-M-39 Enzyme Are the Major Extended-Spectrum Beta-Lactamases in Multiple Escherichia coli Clones Isolated in Tel Aviv, IsraelChmelnitsky, I. / Carmeli, Y. / Leavitt, A. / Schwaber, M. J. / Navon-Venezia, S. et al. | 2005
- 4751
-
Combination Therapy with Terbinafine and Amphotericin B in a Rabbit Model of Experimental Invasive AspergillosisKirkpatrick, W. R. / Vallor, A. C. / McAtee, R. K. / Ryder, N. S. / Fothergill, A. W. / Rinaldi, M. G. / Patterson, T. F. et al. | 2005
- 4754
-
Increased Mutation Frequencies in Escherichia coli Isolates Harboring Extended-Spectrum beta-LactamasesBaquero, M.-R. / Galan, J. C. / del Carmen Turrientes, M. / Canton, R. / Coque, T. M. / Martinez, J. L. / Baquero, F. et al. | 2005
- 4757
-
Activities of Flucytosine, Fluconazole, Amphotericin B, and Micafungin in a Murine Model of Disseminated Infection by Candida glabrataMarine, M. / Serena, C. / Fernandez-Torres, B. / Pastor, F. J. / Guarro, J. et al. | 2005
- 4760
-
Kinetics Study of KPC-3, a Plasmid-Encoded Class A Carbapenem-Hydrolyzing beta-LactamasesAlba, J. / Ishii, Y. / Thomson, K. / Moland, E. S. / Yamaguchi, K. et al. | 2005
- 4763
-
AmpC and OprD Are Not Involved in the Mechanism of Imipenem Hypersusceptibility among Pseudomonas aeruginosa Isolates Overexpressing the mexCD-oprJ Efflux PumpWolter, D. J. / Hanson, N. D. / Lister, P. D. et al. | 2005
- 4767
-
TLA-2, a Novel Ambler Class A Expanded-Spectrum beta-LactamaseGirlich, D. / Poirel, L. / Schluter, A. / Nordmann, P. et al. | 2005
- 4771
-
Recombination between the dfrA12-orfF-aadA2 Cassette Array and an aadA1 Gene Cassette Creates a Hybrid Cassette, aadA8bGestal, A. M. / Stokes, H. W. / Partridge, S. R. / Hall, R. M. et al. | 2005
- 4775
-
mmpL7 Gene of Mycobacterium tuberculosis Is Responsible for Isoniazid Efflux in Mycobacterium smegmatisPasca, M. R. / Guglierame, P. / De Rossi, E. / Zara, F. / Riccardi, G. et al. | 2005
- 4778
-
Differential Antibiotic Susceptibilities of Starved Mycobacterium tuberculosis IsolatesXie, Z. / Siddiqi, N. / Rubin, E. J. et al. | 2005
- 4781
-
Use of an Efflux-Deficient Streptococcus pneumoniae Strain Panel To Identify ABC-Class Multidrug Transporters Involved in Intrinsic Resistance to Antimicrobial AgentsRobertson, G. T. / Doyle, T. B. / Lynch, A. S. et al. | 2005
- 4784
-
High Prevalence of Glycopeptide Resistance Genes vanB, vanD, and vanG Not Associated with Enterococci in Human Fecal FloraDomingo, M.-C. / Huletsky, A. / Giroux, R. / Boissinot, K. / Picard, F. J. / Lebel, P. / Ferraro, M. J. / Bergeron, M. G. et al. | 2005
- 4787
-
Efficacy of Penicillin versus Cefdinir in Eradication of Group A Streptococci and Tonsillar FloraBrook, I. / Foote, P. A. et al. | 2005
- 4789
-
Therapeutic Effects of Bacteriophage Cpl-1 Lysin against Streptococcus pneumoniae Endocarditis in RatsEntenza, J. M. / Loeffler, J. M. / Grandgirard, D. / Fischetti, V. A. / Moreillon, P. et al. | 2005
- 4793
-
Recovery of Interfering Bacteria in the Nasopharynx following Antimicrobial Therapy of Acute Maxillary Sinusitis with Telithromycin or Amoxicillin-ClavulanateBrook, I. / Hausfeld, J. N. et al. | 2005
- 4795
-
Effectiveness of Anidulafungin in Eradicating Candida Species in Invasive CandidiasisPfaller, M. A. / Diekema, D. J. / Boyken, L. / Messer, S. A. / Tendolkar, S. / Hollis, R. J. / Goldstein, B. P. et al. | 2005
- 4798
-
Multiplex PCR for Simultaneous Detection of Macrolide and Tetracycline Resistance Determinants in StreptococciMalhotra-Kumar, S. / Lammens, C. / Piessens, J. / Goossens, H. et al. | 2005
- 4801
-
New Mycobacterium avium Antifolate Shows Synergistic Effect when Used in Combination with Dihydropteroate Synthase InhibitorsSuling, W. J. / Seitz, L. E. / Reynolds, R. C. / Barrow, W. W. et al. | 2005
- 4804
-
Impact of Mass Distribution of Azithromycin on the Antibiotic Susceptibilities of Ocular Chlamydia trachomatisSolomon, A. W. / Mohammed, Z. / Massae, P. A. / Shao, J. F. / Foster, A. / Mabey, D. C. W. / Peeling, R. W. et al. | 2005
- 4807
-
Mutations Conferring Drug Resistance in Malaria Parasite Drug Transporters Pgh1 and PfCRT Do Not Affect Steady-State Vacuolar Ca^2^+Biagini, G. A. / Bray, P. G. / Ward, S. A. / Fidock, D. A. et al. | 2005
- 4809
-
First Outbreak of Klebsiella pneumoniae Clinical Isolates Producing GES-5 and SHV-12 Extended-Spectrum beta-Lactamases in KoreaJeong, S. H. / Bae, I. K. / Kim, D. / Hong, S. G. / Song, J. S. / Lee, J. H. / Lee, S. H. et al. | 2005
- 4811
-
Clinical Isolates of the Spain^1^4-5 Clone of Streptococcus pneumoniae Carry a Recombinant rpoB GeneFerrandiz, M. J. / Perez-Trallero, E. / Marimon, J. M. / de la Campa, A. G. et al. | 2005
- 4814
-
Pharmacokinetics of Colistin Methanesulfonate and Colistin in a Critically Ill Patient Receiving Continuous Venovenous HemodiafiltrationLi, J. / Rayner, C. R. / Nation, R. L. / Deans, R. / Boots, R. / Widdecombe, N. / Douglas, A. / Lipman, J. et al. | 2005
- 4816
-
Improved Outcomes with Linezolid for Methicillin-Resistant Staphylococcus aureus Infections: Better Drug or Reduced Vancomycin Susceptibility?: LetterHowden, B. P. / Charles, P. G. P. / Johnson, P. D. R. / Ward, P. B. / Grayson, M. L. et al. | 2005
- 4816
-
Improved Outcomes with Linezolid for Methicillin-Resistant Staphylococcus aureus Infections: Better Drug or Reduced Vancomycin Susceptibility?: ReplyWeigelt, J. A. / Itani, K. / Stevens, D. / Lau, W. / Dryden, M. / Knirsch, C. et al. | 2005