Cofactor amplification of C5a/C5a des Arg chemotactic activity in physiological fluids (English)
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MOLECULAR IMMUNOLOGY
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47
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2290
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2010
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- Article (Journal) / Print
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Title:Cofactor amplification of C5a/C5a des Arg chemotactic activity in physiological fluids
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Published in:MOLECULAR IMMUNOLOGY ; 47, 13 ; 2290
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Publication date:2010-01-01
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
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Table of contents – Volume 47, Issue 13
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2153
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PrefaceGhebrehiwet, B. / Kew, R. R. / Peerschke, E. I. et al. | 2010
- 2154
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New insights into the molecular mechanisms of classical complement activationKojouharova, M. / Reid, K. / Gadjeva, M. et al. | 2010
- 2161
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The plasma bradykinin-forming pathways and its interrelationships with complementKaplan, A. P. / Ghebrehiwet, B. et al. | 2010
- 2170
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Complement activation on platelets: Implications for vascular inflammation and thrombosisPeerschke, E. I. / Yin, W. / Ghebrehiwet, B. et al. | 2010
- 2176
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Role and mechanism of action of complement in regulating T cell immunityDunkelberger, J. R. / Song, W. C. et al. | 2010
- 2187
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Complement control protein factor H: The good, the bad, and the inadequateFerreira, V. P. / Pangburn, M. K. / Cortes, C. et al. | 2010
- 2198
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Beta-glycan linkage specificity and the role of properdin in activation of the alternative complement pathwayAgarwal, S. / Ram, S. / Huang, H. / Spechtl, C. A. / Ostroff, G. R. / Levitz, S. M. / Rice, P. A. et al. | 2010
- 2198
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Complement activation and cerebral injury following ischemic strokeElvington, A. / Atkinson, C. / Kulik, L. / Zhu, H. / Yu, J. / Kindy, M. S. / Morgan, B. P. / Holers, V. M. / Tomlinson, S. et al. | 2010
- 2199
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C3a and adverse pregnancy outcomesLynch, A. / Murphy, J. / Gibbs, R. / Giclas, P. / Salmon, J. / Holers, V. M. et al. | 2010
- 2199
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The complement system in obesityLynch, A. / Eckel, R. H. / Murphy, J. / Giclas, P. / Holers, V. M. et al. | 2010
- 2199
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Procarboxypeptidase R deficiency causes increased lethality in concanavalin A-induced hepatitis in female miceAsai, S. / Imai, M. / Kimbara, N. / Tada, T. / Campbell, W. / Okada, H. / Okada, N. et al. | 2010
- 2200
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Mannose binding lectin as a target for neuroprotectionOrsini, F. / Zanier, E. R. / Gesuete, R. / Stravalaci, M. / De Blasio, D. / Oortwijn, B. / Mannesse, M. L. / Gobbi, M. / De Simoni, M. G. et al. | 2010
- 2200
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Proteomics-based discovery of an abnormal, internally duplicated CFHR1 protein which associates with renal pathology in a Spanish familyAbarrategui-Garrido, C. / Martinez-Barricarte, R. / Lopez-Lera, A. / Fariza-Requejo, E. / Ruivo, C. / Bedoya-Perez, R. / Cordoba, S. R. / Lopez-Trascasa, M. / Sanchez-Corral, P. et al. | 2010
- 2201
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Novel C3 convertase gain of function in atypical haemolytic uraemic syndrome, caused by a frequent mutation in C3Roumenina, L. T. / Frimat, M. / Hue, C. / Chauvet, S. / Bigot, S. / Satchell, S. C. / Mathieson, P. W. / Sautes-Fridman, C. / Atkinson, J. / Halbwachs-Mecarelli, L. et al. | 2010
- 2201
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Inhibition of mannose-binding lectin preserves renal function in a rat model of renal ischemia reperfusion injuryvan der Pol, P. / Roos, A. / Berger, S. P. / Bajema, I. M. / Stahl, G. L. / Gijlswijk, D. J. / Schlagwein, N. / Daha, M. R. / van Kooten, C. et al. | 2010
- 2201
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Human CFH rapidly reverses renal complement deposition in factor H-deficient miceFakhouri, F. / de Jorge, E. G. / Brune, F. / Azam, P. / Cook, H. T. / Pickering, M. C. et al. | 2010
- 2202
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Targeted complement inhibition significantly ameliorates ischemia reperfusion induced isograft inflammation in a murine model of cardiac transplantationAtkinson, C. / He, S. / Morris, K. / Casey, S. / Goddard, M. / Tomlinson, S. et al. | 2010
- 2202
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Detection of C3 nephritic factor in patients with dense deposit diseaseZhang, Y. / Smith, R. J. et al. | 2010
- 2202
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Recurrence of complement factor H-related protein 5 nephropathy in a renal transplantVernon, K. A. / Gale, D. P. / de Jorge, E. G. / McLean, A. G. / Maxwell, P. H. / Pickering, M. C. / Cook, H. T. et al. | 2010
- 2203
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Complement inhibitor C4b-binding protein (C4BP) binding to islet amyloid polypeptide prevents complement activation and further fibril formation in the endocrine pancreasSjolander, J. / Westermark, G. T. / Renstrom, E. / Blom, A. M. et al. | 2010
- 2203
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Integrating cytotopic strategy in transplantation: (1) Design of locally-acting coagulation inhibitors for use with anti-complement therapeuticsMelchionna, T. / Karegli, J. / Farrar, C. A. / McVey, J. H. / Dorling, A. / Sacks, S. H. / Smith, R. A. et al. | 2010
- 2203
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Integrating cytotopic strategy in transplantation: (2) Localised co-inhibition of complement and coagulation in high risk renal transplantationKaregli, J. / Farrar, C. A. / Melchionna, T. / Smith, R. A. / Sacks, S. H. et al. | 2010
- 2204
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In vitro characterisation of an imaging ligand for detection of C3d deposition in vivoBadar, A. / De Freitas, S. / Yahya, M. N. / McDonnell, J. M. / Thakor, D. / Smith, R. A. / Sacks, S. H. / Mullen, G. E. et al. | 2010
- 2204
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M-ficolin serum concentrations are related to early-onset neonatal sepsis and circulating phagocytesSchlapbach, L. J. / Thiel, S. / Mattmann, M. / Nelle, M. / Wagner, B. / Ammann, R. A. / Aebi, C. / Jensenius, J. C. et al. | 2010
- 2205
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Ornithodoros moubata complement inhibitor (OmCI)-A novel and efficient C5 inhibitor in the pigBarratt-Due, A. / Thorgersen, E. B. / Lindstad, J. / Pharo, A. / Nunn, M. A. / Mollnes, T. E. et al. | 2010
- 2205
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Functional implications of the recognition of complement factor H-related protein 1 (CFHR1) by anti-factor H autoantibodies in autoimmune haemolytic uraemic syndromeSanchez-Corral, P. / Strobel, S. / Abarrategui-Garrido, C. / Seeberger, H. / Fariza-Requejo, E. / Jozsi, M. et al. | 2010
- 2205
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Complement activation during liver transplantation has relevance for patients with atypical hemolytic uremic syndromeKoskinen, A. / Tukiainen, E. / Nordin, A. / Makisalo, H. / Hockerstedt, K. / Isoniemi, H. / Nilsson, B. / Jokiranta, T. S. et al. | 2010
- 2206
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Frequent occurrence of antibodies against C1 inhibitor in patients with hereditary angioedema is unrelated to previous treatment with C1 inhibitor concentrateVarga, L. / Fust, G. / Csuka, D. / Farkas, H. et al. | 2010
- 2206
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Creation of a mouse line lacking expression of the Cr1 protein but maintaining cell and stage specific expression of the Cr2 proteinDonius, L. R. / Weis, J. H. et al. | 2010
- 2206
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C5a regulates antigen uptake and processing in mDCs as a novel means to regulate adaptive immune responses in experimental allergic asthmaSchmudde, I. / Laumonnier, Y. / Kohl, J. et al. | 2010
- 2207
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C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone miceShagdarsuren, E. / Bidzhekov, K. / Mause, S. / Simsekyilmaz, S. / Polakowski, T. / Hawlisch, H. / Zernecke, A. / Weber, C. et al. | 2010
- 2207
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C3-dependent microglial priming caused by deletion of the membrane complement regulator CrryRamaglia, V. / Hughes, T. R. / Donev, R. M. / Ruseva, M. M. / Wu, X. / Neal, J. W. / Morgan, B. P. et al. | 2010
- 2207
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Complement-dependent lysis of mAb-opsonized B cells can increase resistance of naive B cells to subsequent attack by mAb and complementTaylor, R. P. / Beum, P. V. / Lindorfer, M. A. / Pawluzckowycz, A. W. / Beurskens, F. J. / van de Winkel, J. G. / Parren, P. W. et al. | 2010
- 2208
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Functional deficiency of mannose-binding lectin is associated with improved outcome after acute ischemic strokeOsthoff, M. / Katan, M. / Fluri, F. / Danner, D. / Christ-Crain, M. / Trendelenburg, M. et al. | 2010
- 2208
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Platelet C4d is associated with all-cause mortality in patients with systemic lupus erythematosusKao, A. H. / McBurney, C. / Sattar, A. / Wilson, N. L. / Rutman, S. / Paul, B. / Navratil, J. S. / Manzi, S. / Ahearn, J. M. et al. | 2010
- 2208
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Anti-C1q autoantibodies do not correlate with the occurrence or severity of experimental lupus nephritisBigler, C. / Hopfer, H. / Danner, D. / Mihatsch, M. J. / Trendelenburg, M. et al. | 2010
- 2209
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Epitope fine mapping and isotype analysis of anti-factor H autoantibodies demonstrate antibody heterogeneity and reveal the molecular basis of autoimmune haemolytic uraemic syndromeSeeberger, H. / Strobel, S. / Lehtinen, M. J. / Jokiranta, T. S. / Jozsi, M. et al. | 2010
- 2209
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The terminal pathway of complement in hepatic ischemia/reperfusion injury and regenerationMorris, K. / He, S. / Atkinson, C. / Morgan, B. P. / Tomlinson, S. et al. | 2010
- 2210
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Mutations in complement regulatory proteins predispose to preeclampsiaSalmon, J. E. / Triebwasser, M. / Liszewski, M. K. / Kavanagh, D. / Heuser, C. / Roumenina, L. / Branch, W. / Goodship, T. / Fremeaux-Bacchi, V. / Atkinson, J. P. et al. | 2010
- 2210
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WIESLAB Alternative Pathway assay as a specific test to support the diagnosis of atypical hemolytic-uremic syndrome: Results of a series of nine casesProhaszka, Z. / Szilagyi, A. / Fust, G. / Varga, L. et al. | 2010
- 2210
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Properdin homeostasis requires the turnover of alternative complement pathwayWu, X. / Xu, T. Q. / Atkinson, J. P. et al. | 2010
- 2211
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Complement regulation at necrotic cell lesions is impaired by the AMD associated Factor H-H402 risk variantLauer, N. / Mihlan, M. / Hartmann, A. / Schlotzer-Schrehard, U. / Keilhauer, C. / Scholl, H. P. / Charbel-Issa, P. / Holz, F. / Weber, B. H. / Skerka, C. et al. | 2010
- 2211
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Imbalance of complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age related macular degeneration (AMD)Lauer, N. / Fritsche, L. G. / Weber, B. H. / Hartmann, A. / Keilhauer, C. N. / Halbich, S. / Oppermann, M. / Pandey, M. / Kohl, J. / Zipfel, P. F. et al. | 2010
- 2212
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M-ficolin concentration is associated with severe infections in haematological cancerAmeye, L. / Paesmans, M. / Aoun, M. / Thiel, S. / Jensenius, J. C. et al. | 2010
- 2212
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A role for complement in paraquat-induced acute lung injurySun, S. / Wang, H. / Zhao, G. / An, Y. / Du, L. / Song, H. / Guo, Y. / Guo, R. / Jiang, S. / Qiao, F. et al. | 2010
- 2212
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Human C3 mutation associated with Dense Deposit Disease unravels distinct structural requirements for factor H, MCP and DAF regulationMartinez-Barricarte, R. / Heurich, M. / Valdes-Canero, F. / Vazquez-Martul, E. / Torreira, E. / Montes, T. / Tortajada, A. / Pinto, S. / Lopez-Trascasa, M. / Morgan, B. P. et al. | 2010
- 2213
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Fluid phase complement alternative pathway dysregulation: A major physiopathological mechanism in anti-FH autoantibodies-associated HUSBlanc, C. / Roumenina, L. / Hue, C. / Fridman, W. H. / Sautes-Fridman, C. / Fremeaux-Bacchi, V. / Dragon-Durey, M. A. et al. | 2010
- 2213
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Functional measurement of the complement lectin pathway in normal pregnancy and preeclampsia: A case-control studyCsuka, D. / Derzsy, Z. / Varga, L. / Fust, G. / Molvarec, A. / Rigo, J. / Prohaszka, Z. et al. | 2010
- 2214
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The role of complement in the pathogenesis of dextran sulfate sodium induced colitisSchepp-Berglind, J. / Atkinson, C. / Tomlinson, S. et al. | 2010
- 2214
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Clinical features of anti-FH auto antibodies-associated HUS: A typical onset but an atypical outcomeDragon-Durey, M. A. / Sethi, S. K. / Bagga, A. / Blanc, C. / Blouin, J. / Ranchin, B. / Andre, J. L. / Takagi, N. / Cheong, H. I. / Hari, P. et al. | 2010
- 2214
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Modulating complement activation on tumor cellsRapisardo, M. / Huang, Y. / Atkinson, C. / Varela, J. / Tomlinson, S. et al. | 2010
- 2215
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The alternative and terminal pathways of complement mediate post-traumatic spinal cord inflammation and injuryQiao, F. / Atkinson, C. / Song, H. / Morgan, B. P. / Tomlinson, S. et al. | 2010
- 2215
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Modelling of the C5a receptor by iterative mutationHolt, J. R. / Monk, P. N. / Fairlie, D. P. / Madala, P. K. et al. | 2010
- 2215
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The human complement receptor type 2/factor H fusion protein TT30, an alternative pathway specific complement inhibitor, prevents hemolysis of erythrocytes from patients with paroxysmal nocturnal hemoglobinuria by membrane-targeting of factor H activityRisitano, A. M. / Pascariello, C. / Selleri, C. / Del Vecchio, L. / Sica, M. / Fridkis-Hareli, M. / Mazsaroff, I. / Horvath, C. J. / Holers, V. M. et al. | 2010
- 2216
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Complement lectin pathway genotypes associated with placental malariaHolmberg, V. / Onkamo, P. / Lahtela, E. / Lahermo, P. / Mockenhaupt, F. P. / Meri, S. et al. | 2010
- 2216
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Complement component C3 aberrations in patients with atypical haemolytic uraemic syndrome (aHUS)Volokhina, E. / Westra, D. / HendriksFranssen, M. / van Loon, E. / Huigen, M. / Gros, P. / van de Kar, N. / van den Heuvel, L. et al. | 2010
- 2216
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Analysis of genes coding for CD46, CD55 and C4b-binding protein in patients with idiopathic, recurrent, spontaneous pregnancy lossBergstrom, F. / Mercier, E. / Fremeaux-Bacchi, V. / Gris, J. C. / Blom, A. M. et al. | 2010
- 2217
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C4 gene copy number variation in healthy Italian and systemic sclerosis patientsZorzetto, M. / Boiocchi, C. / Bozzini, S. / Cuccia, M. et al. | 2010
- 2217
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BLAST searches of the NCBI whole genome shotgun sequence database identify complement factor H-like sequences in lower primatesKuttner-Kondo, L. A. et al. | 2010
- 2217
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The risk alleles of age related macular degeneration in CFH and C3 do not play a major role in rheumatoid arthritisTrouw, L. A. / Bohringer, S. / Stahl, G. L. / Kurreeman, F. A. / Houwing-Duistermaat, J. J. / Huizinga, T. W. / Plenge, R. M. / Toes, R. E. et al. | 2010
- 2218
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Age-specific normal ranges of lectin-pathway components in human serum: Mannose-binding lectin (MBL), M-, L-, and H-ficolin, and MBL-associated serine protease-2 (MASP-2)Sallenbach, S. / Thiel, S. / Aebi, C. / Otth, M. / Bigler, S. / Jensenius, J. C. / Schlapbach, L. J. / Ammann, R. A. et al. | 2010
- 2218
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Development of a functional ELISA for detecting Ficolin-3 and downstream complement deficienciesSommarin, Y. / Wieslander, J. / Persson, A. / Honore, C. / Garred, P. et al. | 2010
- 2219
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Molecular basis of complement C1r deficiency in a male African American patient with systemic lupus erythematosusWu, Y. L. / Brookshire, B. / Yu, C. Y. / Arnett, F. et al. | 2010
- 2219
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Factor H protects stressed but not quiescent glomerular endothelial cells from complement-mediated damageRoumenina, L. T. / Frimat, M. / Poitou, C. / Malina, M. / Bigot, S. / Dragon-Durey, M. A. / Satchell, S. C. / Mathieson, P. W. / Halbwachs-Mecarelli, L. / Fremeaux-Bacchi, V. et al. | 2010
- 2219
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Functional analysis of amino acid substitution variations in the Ficolin-3 gene (FCN3)Hummelshoj, T. / Nissen, J. / Munthe-Fog, L. / Ma, Y. J. / Madsen, H. O. / Garred, P. et al. | 2010
- 2220
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Association of Ficolin 1 promoter polymorphisms with clinical leprosyBoldt, A. B. / Sanchez, M. I. / Stahlke, E. R. / Messias-Reason, I. J. et al. | 2010
- 2220
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Multiplex sequence-specific PCR reveals association of different masp2 haplotypes with leprosyBoldt, A. B. / Stahlke, E. R. / Messias-Reason, I. J. et al. | 2010
- 2220
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Genotypic diversity of complement component C4 and kidney transplantation outcomeWahrmann, M. / Dohler, B. / Ruthenstroth, A. / Haslacher, H. / Perkmann, T. / Exner, M. / Rees, A. J. / Bohmig, G. A. et al. | 2010
- 2221
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Complement Factor I deficiencies in two non-related Brazilian families: Association with purpura, arthritis and pulmonary vasculitisDelcolli, M. I. / Antonialli, R. / Florido, M. P. / Magalhaes, C. M. / Isaac, L. et al. | 2010
- 2221
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Arg127 of complement regulatory protein Factor H is responsible for the secretion rate of this protein by human fibroblastsAlbuquerque, J. A. / Lamers, M. / Santos, M. D. / Isaac, L. et al. | 2010
- 2222
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The NC4 domain of the cartilage-specific collagen IX is a novel complement inhibitorKalchishkova, N. / Heinegard, D. / Blom, A. M. et al. | 2010
- 2222
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Contribution of chondroitin sulfate A to the binding of complement proteins to activated plateletsNilsson, P. H. / Hamad, O. A. / Lasaosa, M. / Ricklin, D. / Lambris, J. D. / Nilsson, B. / Ekdahl, K. N. et al. | 2010
- 2222
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Characterization of cellular C5aR expression under resting and inflammatory conditions using a novel GFP knock-in mouseDunkelberger, J. / Zhou, L. / Miwa, T. / Song, W. C. et al. | 2010
- 2223
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Direct interaction between CD91 and C1qDuus, K. / Hansen, E. W. / Tacnet, P. / Frachet, P. / Arlaud, G. J. / Thielens, N. M. / Houen, G. et al. | 2010
- 2223
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Evidence that the full-length gC1qR (residues 1-282) is expressed on the cell surfaceHosszu, K. K. / Vinayagasundaram, U. / Habiel, D. / Ji, Y. / Vinayagasundaram, R. / Peerschke, E. I. / Ghebrehiwet, B. et al. | 2010
- 2223
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Differential expression and function of complement receptor type 1 (CD35) and 2 (CD21) on human B lymphocytesErdei, A. / Kremlitzka, M. / Isaak, A. / Prechl, J. / Bajtay, Z. et al. | 2010
- 2224
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Complement receptors and hormonal contraceptives: Expression and role of CR1/CR3 in mediating the oxidative burst of neutrophilsBertozi, R. I. / Torqueti, M. R. / Azzolini, A. E. / Pereira-Crott, L. S. / Lucisano-Valim, Y. M. / Marzocchi-Machado, C. M. et al. | 2010
- 2224
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Ectosomes of stored platelets (PLT-Ect)Sadallah, S. / Eken, C. / Martin, P. / Schifferli, J. et al. | 2010
- 2224
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The complement regulator CD46 regulates unconventional gammadelta T cell responsesLe Friec, G. / Vantourout, P. / Cardone, J. / Roberts, A. / Hayday, A. / Kemper, C. et al. | 2010
- 2225
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Circadian rhythm regulates circulating complement factors and the immunoregulatory properties of C5aReis, E. S. / Lange, T. / Born, J. / Kohl, J. et al. | 2010
- 2225
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Reduced B cell anergy in mice deficient in CD21Carroll, M. C. / Ma, M. / Agemang, A. et al. | 2010
- 2225
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Properdin is a pattern recognition molecule for viral double-stranded RNA and contributes to host antiviral innate immune responseZhang, X. / Kimura, Y. / Miwa, T. / Ni, H. / Kariko, K. / Weissman, D. / Song, W. C. et al. | 2010
- 2226
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IL-4 induces up-regulation of the junction protein claudin-5 in vascular endothelial cells, which is required for protection from killing by the membrane attack complexWasiluk, K. R. / Goldish, D. / Benson, B. A. / Vercellotti, G. / Dalmasso, A. P. et al. | 2010
- 2226
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Inter alpha inhibitor (IaI) as novel inhibitor of human complement systemOkroj, M. / Sjolander, J. / Blom, A. M. et al. | 2010
- 2227
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SIGN-R1-expressing dendritic cells are important for humoral immunity to influenza virusPitcher, L. A. / Gonzalez, S. F. / Lukacs-Kornek, V. / Kuligowski, M. P. / Kim, Y. A. / Martinez-Pomares, L. / Gordon, S. / Turley, S. J. / Carroll, M. C. et al. | 2010
- 2227
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Sublytic complement protects tumor cells against TNF-alpha-induced apoptosisLiu, L. / Li, W. / Li, Z. / Kirschfink, M. et al. | 2010
- 2227
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Visualizing B cell transport of immune complexes via CD21Kim, Y. A. / Carroll, M. C. et al. | 2010
- 2227
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A complement-IL-4 regulatory circuit controls liver regenerationDeAngelis, R. A. / Markiewski, M. M. / Maurya, M. R. / Gupta, S. / Subramaniam, S. / Lambris, J. D. et al. | 2010
- 2228
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Ligation of complement receptor 1 increases red blood cell membrane deformabilityGlodek, A. M. / Mirchev, R. / Golan, D. E. / Shevkoplyas, S. S. / Burns, J. / Nicholson-Weller, A. / Ghiran, I. C. et al. | 2010
- 2228
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A novel chimeric antigen hC3d-TTCF-hC4BP interacts with mCR2 allowing extensive testing as a novel adjuvant using murine modelsHe, Y. / Palmer, J. M. / Knight, A. M. / Marchbank, K. J. et al. | 2010
- 2228
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Co-localization of gC1qR with DC-SIGN on the surface of immature dendritic cellsHosszu, K. K. / Vinayagasundaram, U. / Vinayagasundaram, R. / Santiago-Schwarz, F. / Peerschke, E. I. / Ghebrehiwet, B. et al. | 2010
- 2229
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Lymph node macrophages bind influenza virus in an MBL-dependent manner but they are not required for humoral immunity to influenzaGonzalez, S. F. / Degn, S. E. / Kuligowski, M. P. / Pitcher, L. A. / Cloninger, M. / Carroll, M. C. et al. | 2010
- 2229
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CD46: Just a Notch up your common complement regulatorLe Friec, G. / Bugeon, L. / Dallman, M. / Kemper, C. et al. | 2010
- 2229
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MBL/Ficolin associated protein-1 (MAP-1) may function as a local lectin pathway specific complement inhibitorSkjodt, M. O. / Hummelshoj, T. / Palarasah, Y. / Honore, C. / Koch, C. / Skjodt, K. / Garred, P. et al. | 2010
- 2230
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CD46 favours immunoregulation by promoting the switch of Th1 cells into IL-10 producing Treg cellsCardone, J. / Le Friec, G. / Fuchs, A. / Atkinson, J. P. / Cope, A. / Kemper, C. et al. | 2010
- 2230
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Complement differentially modulates dendritic/NK cell activation which engages myeloid derived suppressor cellsQing, X. / Koo, G. C. / Salmon, J. et al. | 2010
- 2231
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Anaphylatoxin C5a is an important regulator of natural killer cell functionLi, K. / Wang, N. / Peng, Q. / Sacks, S. H. / Martin-Fontecha, A. / Zhou, W. et al. | 2010
- 2231
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Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human bloodChristiansen, D. / Brekke, O. L. / Stenvik, J. / Lambris, J. D. / Espevik, T. / Mollnes, T. E. et al. | 2010
- 2231
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The classical and alternative complement pathways play different roles in the immune responseFrank, M. M. / Hester, G. / Jiang, H. / Zhang, H. / DiLillo, D. / Kelsoe, G. / Hauck, A. et al. | 2010
- 2232
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Expression of complement components, receptors and regulators by human dendritic cells and the role of C3a and C5a in modulation of dendritic cell functionLi, K. / Fazekasova, H. / Gomes, C. / Wang, N. / Sagoo, P. / Peng, Q. / Khamri, W. / Sacks, S. H. / Lombardi, G. / Zhou, W. et al. | 2010
- 2232
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M-ficolin interacts with the long-chain pentraxin PTX3. A novel case of crosstalk between pattern recognition proteins?Gout, E. / Doni, A. / Lacroix, M. / Arlaud, G. J. / Mantovani, A. / Thielens, N. M. et al. | 2010
- 2232
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A novel role for C5a in B-cell regulation driving the pathology in immune complex nephritisPandey, M. K. / Figge, J. / Karsten, C. M. / Madaio, M. / Gerard, C. / Kohl, J. et al. | 2010
- 2233
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Inhibition of the alternative pathway of complement activation reduces inflammation in experimental autoimmune uveoretinitisChen, M. / Muckersie, E. / Forrester, J. V. / Xu, H. et al. | 2010
- 2233
-
Recombinant form of human wild type mannan-binding lectin (MBL/A) but not its structural variant (MBL/C) promotes phagocytosis of zymosan by activating complementRajagopalan, R. / Nyaundi, T. / Salvi, V. P. / Rawal, N. et al. | 2010
- 2234
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Biocompatibility of candidate materials for an implantable glucose sensor in terms of complement and neutrophil activating propertiesSokolov, A. / Hellerud, B. C. / Pharo, A. / Johannessen, E. / Mollnes, T. E. et al. | 2010
- 2234
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MBL and PTX3 interaction provokes powerful antifungal activity by communication between the lectin and classical complement pathways via C1q recruitmentMa, Y. J. / Doni, A. / Honore, C. / Skjoedt, M. O. / Arendrup, M. / Mantovani, A. / Garred, P. et al. | 2010
- 2234
-
Interaction of the long pentraxin PTX3 with soluble complement inhibitorsBraunschweig, A. / Jozsi, M. et al. | 2010
- 2235
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Double deficiency of C5aR/C3aR significantly prevents mice from renal ischemia/reperfusion injuryPeng, Q. / Xing, G. / Li, K. / Wang, N. / Sacks, S. H. / Zhou, W. et al. | 2010
- 2235
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Deficiency of C5aR prolongs renal allograft survivalLi, Q. / Peng, Q. / Xing, G. / Li, K. / Wang, N. / Farrar, C. A. / Meader, L. / Sacks, S. H. / Zhou, W. et al. | 2010
- 2235
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The role of cholinergic anti-inflammatory pathway in immune stimulationVukelic, M. / Koo, G. / Salmon, J. E. et al. | 2010
- 2236
-
Functional recruitment of C4b-binding protein to Salmonella RckHo, D. K. / Jarva, H. / Blom, A. M. / Meri, S. et al. | 2010
- 2236
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Elevated cytokine concentrations in serum compared to plasma samples from healthy humans is not explained by in vitro complement activationLudviksen, J. K. / Henno, L. T. / Brekke, O. L. / Christiansen, D. / Fure, H. / Nielsen, E. W. / Mollnes, T. E. et al. | 2010
- 2236
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CRASP2 of Candida albicans binds C4b-binding protein and mediates fungal contact with human endothelial cellsLuo, S. / Blom, A. M. / Rupp, S. / Hube, B. / Hipler, U. C. / Skerka, C. / Zipfel, P. F. et al. | 2010
- 2237
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CRASP2 of the human pathogenic yeast Candida albicans is a complement inhibitor that inhibits C3 conversionLuo, S. / Hartmann, A. / Dahse, H. M. / Skerka, C. / Zipfel, P. F. et al. | 2010
- 2237
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Properdin is required for autologous tissue injury but not systemic complement consumption associated with uncontrolled alternative pathway activationLesher, A. M. / Kimura, Y. / Gullipalli, D. / Zhou, L. / Herbert, A. P. / Barlow, P. / Skerka, C. / Zipfel, P. / Miwa, T. / Song, W. C. et al. | 2010
- 2237
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Pseudomonas aeruginosa CRASP-2 is a surface protein that uses the human terminal complement regulator vitronectin for protection against complement-mediated attackHallstrom, T. / Uhde, M. / Morgelin, M. / Skerka, C. / Zipfel, P. F. et al. | 2010
- 2238
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EspP, a serine protease of enterohaemorrhagic Escherichia coli, impairs complement activation by cleaving complement factors C3/C3b and C5Orth, D. / Ehrlenbach, S. / Brockmeyer, J. / Khan, A. B. / Huber, G. / Karch, H. / Sarg, B. / Lindner, H. / Wurzner, R. et al. | 2010
- 2238
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Binding characteristics and immunogenicity of modified factor H binding protein from Neisseria meningitidisTan, L. / Caesar, J. / Li, Y. / Exley, R. / Kugelberg, E. / Zhang, Q. / Lea, S. / Tang, C. et al. | 2010
- 2238
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C-reactive protein (CRP) facilitates non-inflammatory removal of apoptotic particles by recruitment of Factor H family proteinsMihlan, M. / Stippa, S. / Jozsi, M. / Zipfel, P. F. et al. | 2010
- 2239
-
Inhibition of the human complement component C4 by Flavivirus non-structural protein NS1Avirutnan, P. / Fuchs, A. / Hauhart, R. E. / Somnuke, P. / Youn, S. / Diamond, M. S. / Atkinson, J. P. et al. | 2010
- 2239
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Intact complement C3 binds to Staphylococcus aureus in hyperglycemic conditions without complement activationHair, P. / Cunnion, K. et al. | 2010
- 2239
-
Complement evasion by vesicular stomatitis virus involves recruitment of host complement regulatory proteinsJohnson, J. B. / Lyles, D. S. / Parks, G. D. et al. | 2010
- 2240
-
Identification of a novel complement inhibitor Complin that inhibits activation of factor B and C2Kadam, A. P. / Sahu, A. et al. | 2010
- 2240
-
Proteases of periodontal pathogens Porphyromonas gingivalis, Tannerella forsythia and Prevotella intermedia target all pathways of the complement systemJusko, M. / Potempa, J. / Potempa, M. / Popadiak, K. / Riesbeck, K. / Eick, S. / Blom, A. M. et al. | 2010
- 2240
-
Complement activation on Chlamydia pneumoniae is promoted by direct binding of native properdin to its surfaceCortes, C. / Ferreira, V. P. / Pangburn, M. K. et al. | 2010
- 2241
-
Pathogen-instigated subversive crosstalk between complement and Toll-like receptorsHajishengallis, G. / Wang, M. / Krauss, J. L. / Domon, H. / Hosur, K. B. / Liang, S. / Magotti, P. / Triantafilou, M. / Triantafilou, K. / Lambris, J. D. et al. | 2010
- 2241
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Key role of CD14 in the E. coli- and LPS-induced mRNA down regulation of the C5a receptors CD88 and C5L2Fure, H. / Brekke, O. L. / Lambris, J. D. / Mollnes, T. E. et al. | 2010
- 2241
-
The role of complement inhibitor C4b-binding protein in pneumococcal infectionMalm, S. / Agarwal, V. / Riesbeck, K. / Blom, A. M. et al. | 2010
- 2242
-
Factor H Tyr402 binds more efficiently to Leptospira than Factor H His402 but both variants exhibit similar cofactor activitiesSilva, A. S. / Valencia, M. M. / Barbosa, A. S. / Isaac, L. et al. | 2010
- 2242
-
Mechanism of complement regulator Factor H mediated pneumococcal uptake by human cellsAgarwal, V. / Asmat, T. / Luo, S. / Zipfel, P. F. / Hammerschmidt, S. et al. | 2010
- 2243
-
The meningococcal vaccine candidate Neisserial surface protein A (NspA) binds to Factor H and enhances meningococcal resistance to complementLewis, L. A. / Ngampasutadol, J. / Wallace, R. / Reid, J. E. / Vogel, U. / Ram, S. et al. | 2010
- 2243
-
Characterization of the unique complement resistance mechanisms of the periodontal pathogen, Treponema denticola: Insight into the survival strategies within the periodontal pocketMcDowel, J. V. / Paula Goetting-Minesky, M. / Frederick, J. / Miller, D. P. / Christopher Fenno, J. / Marconi, R. T. et al. | 2010
- 2243
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Candida albicans CRASP binds anaphylatoxin C3a and inhibits C3a mediated immune effector functionsKupka, D. / Luo, S. / Hippler, U. C. / Hoffmann, R. / Hube, B. / Rupp, S. / Zipfel, P. F. et al. | 2010
- 2244
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Sequence and structure-function relationships of the Treponema denticola factor H binding protein FhbB: Unique insight into the minimal molecular determinants required for factor H bindingMiller, D. et al. | 2010
- 2244
-
Allosteric inhibition of complement function by the Staphylococcal immune evasion protein EfbRicklin, D. / Chen, H. / Hammel, M. / Garcia, B. L. / McWhorter, W. J. / Sfyroera, G. / Wu, Y. Q. / Tzekou, A. / Li, S. / Geisbrecht, B. V. et al. | 2010
- 2244
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The production of mannan-binding lectin is dependent upon thyroid hormones regardless of the genotype: A cohort study of 95 patients with autoimmune thyroid disordersPotlukova, E. / Jiskra, J. / Freiberger, T. / Limanova, Z. / Zivorova, D. / Malickova, K. / Springer, D. / Grodecka, L. / Antosova, M. / Telicka, Z. et al. | 2010
- 2245
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Antibody-independent classical complement pathway activation by wildtype and LPS O-antigen mutant Francisella tularensis strainsClay, C. D. / Gunn, J. S. / Schlesinger, L. S. et al. | 2010
- 2245
-
Structure and mechanism of action of the FH binding FhbB protein of Treponema denticolaMarconi, R. T. et al. | 2010
- 2245
-
Molecular basis for complement recognition and inhibition by staphylococcal complement inhibitorsGarcia, B. L. / Tzekou, A. / Ricklin, D. / Ramyar, K. X. / McWhorter, W. J. / Geisbrecht, B. V. / Lambris, J. D. et al. | 2010
- 2246
-
Specific antibodies against SmTOR in S. mansoni infected and normal humansLochmatter, C. / List, C. / Schifferli, J. A. et al. | 2010
- 2246
-
Factor H facilitates adherence of Neisseria gonorrhoeae to complement receptor 3 on eukaryotic cellsAgarwal, S. / Ram, S. / Ngampasutadol, J. / Gulati, S. / Zipfel, P. F. / Rice, P. A. et al. | 2010
- 2246
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Trypanosoma cruzi calreticulin, a virulence factor that binds C1/C1q on the parasite surfaceRamirez, G. / Valck, C. / Molina, M. C. / Ribeiro, C. H. / Lopez, N. / Sanchez, G. / Maldonado, I. / Ferreira, V. P. / Schwaeble, W. / Ferreira, A. et al. | 2010
- 2247
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Characterization of antibodies in human serum against group B Neisseria meningitidis that block complement-dependent bactericidal activityRay, T. D. / Lewis, L. A. / Gulati, S. / Rice, P. A. / Ram, S. et al. | 2010
- 2247
-
Species specificity of factor H interaction with the uniquely human pathogen, Neisseria gonorrhoeae, resides in arginine substitution at position 1203 in domain 20Shaughnessy, J. / Ram, S. / Bhattacharjee, A. / Tran, C. / Horvath, G. / Monks, B. / Visintin, A. / Jokiranta, T. S. / Rice, P. A. et al. | 2010
- 2248
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Development and testing of a computer model of complement activation to analyze the effects of genetic variants, mutations and drugs on the complement systemTandon, M. / Pangburn, M. K. et al. | 2010
- 2248
-
Dual binding specificity of a Leptospira-associated complement regulator-acquiring surface protein for human C4BP and Factor HBarbosa, A. S. / Silva, L. B. / Goncales, A. P. / Morais, Z. M. / Vasconcellos, S. A. / Isaac, L. / Abreu, P. A. et al. | 2010
- 2248
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230 Leptospira Immunoglobulin-like proteins bind human complement regulator Factor HValencia, M. M. / Fraga, T. R. / Silva, L. B. / Abreu, P. A. / Barbosa, A. S. / Isaac, L. et al. | 2010
- 2249
-
The role of the complement system in trafficking of a Streptococcus vaccine in the lymph nodeHeesters, B. A. / Gonzalez, S. F. / Carroll, M. C. et al. | 2010
- 2249
-
Requirement of acidic pH for the binding of pentameric C-reactive protein to factor HHammond, D. J. / Singh, S. K. / Pangburn, M. K. / Potempa, L. A. / Agrawal, A. et al. | 2010
- 2249
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Characterization of antibodies in human serum against serogroup B N. meningitidis that block complement-dependent bactericidal activityRay, T. D. / Lewis, L. A. / Gulati, S. / Rice, P. A. / Ram, S. et al. | 2010
- 2250
-
Regulation of neuronal gene and miRNA expression by the complement protein C1q associated with neuroprotectionBenoit, M. / Tenner, A. J. et al. | 2010
- 2250
-
The secreted Ecb and Efb proteins of Staphylococcus aureus enhance binding of factor H to C3b and C3dAmdahl, H. / Jongerius, I. / Pasanen, T. / Lehtinen, M. J. / van Strijp, J. A. / Rooijakkers, S. H. / Jokiranta, T. S. et al. | 2010
- 2250
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A high affinity inhibitor of human CD59 enhances complement-mediated virolysis of HIV-1: Implications for treatment of HIV-1/AIDSHu, W. / Yu, Q. / Hu, N. / Byrd, D. / Amet, T. / Shikuma, C. / Shiramizu, B. / Halperin, J. A. / Qin, X. et al. | 2010
- 2251
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Complement expression in mice throughout neural tube closureCoulthard, L. G. / Costantini, K. J. / Lor, M. / Simmons, D. / Taylor, S. M. / Woodruff, T. M. et al. | 2010
- 2251
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Neutrophil-derived C1q and C3a promote migration and astroglial differentiation of human fetal neural stem cells transplanted immediately after spinal cord injury in immunodeficient miceHooshmand, M. J. / Nguyen, H. X. / Tamaki, S. J. / Uchida, N. / Cummings, B. J. / Anderson, A. J. et al. | 2010
- 2252
-
Lets connect: A novel role for CD46 in tight junction regulationAl-Shouli, S. / Cardone, J. / Sacks, S. / Kemper, C. et al. | 2010
- 2252
-
Complement C5 inhibition attenuates lung inflammation in H1N1 influenzaWeston-Davies, W. / Ryffel, B. / Teixeira, M. M. / Garcia, C. C. / Russo, R. C. / Tavares, L. P. / Nunn, M. et al. | 2010
- 2252
-
Ligands for C1q and factor H on the surface of apoptotic cellsMartin, M. / Leffler, J. / Herbert, A. P. / Norstrom, E. / Barlow, P. N. / Blom, A. M. et al. | 2010
- 2253
-
Investigations on MASP-3 and MAp44, the novel splice product of the MASP-1 geneDegn, S. / Gal, P. / Jensen, L. / Holmvad, S. H. / Jensenius, J. C. / Thiel, S. et al. | 2010
- 2253
-
Role of complement in osteoclast differentiationTu, Z. / Bu, H. / Dennis, J. E. / Lin, F. et al. | 2010
- 2254
-
Caveolae- and lipid rafts-mediated endocytosis of the complement C5b-9 is an essential mechanism for complement resistanceMoskovich, O. / Ehrlich, M. / Fishelson, Z. et al. | 2010
- 2254
-
C5aR protects against folate-deficiency induced neural tube defects in miceCostantini, K. J. / Coulthard, L. G. / Lor, M. / Woodruff, T. M. / Callaway, L. K. / Finnell, R. H. / Taylor, S. M. et al. | 2010
- 2254
-
C5b-9 regulates histone deacetylases and oligodendrocyte-specific gene expressionTegla, C. A. / Cudrici, C. / Vlaicu, S. I. / Khan, A. / Niculescu, F. / Rus, V. / Rus, H. et al. | 2010
- 2255
-
Regulation of C5b-9 elimination by the mitochondrial hsp70 mortalin: Biochemical and cellular analysesSaar, M. / Moskovich, O. / Fishelson, Z. et al. | 2010
- 2255
-
C1q binds deoxyribose and heparan sulfate through neighboring sites of its recognition domain: Implications for the control of C1 activation upon recognition of non-immune targetsGaboriaud, C. / Garlatti, V. / Chouquet, A. / Lunardi, T. / Paidassi, H. / Thielens, N. M. / Arlaud, G. J. et al. | 2010
- 2255
-
M-ficolin, a pathogen-associated molecular pattern recognition molecule produced by monocytesKjaer, T. R. / Thiel, S. / Wittenborn, T. / Jensenius, J. C. et al. | 2010
- 2256
-
Autoactivation of MASP-2: Role of exosite interactionsHarmat, V. / Kocsis, A. / Kiss-Szeman, A. / Pal, G. / Zavodszky, P. / Gal, P. et al. | 2010
- 2256
-
The interactions of thioredoxin and the complement systemKing, B. C. / Nowakowska, J. / Renstrom, E. / Blom, A. M. et al. | 2010
- 2256
-
Analysis of binding sites on complement Factor I that are required for its activityGallego, J. I. / Nita, I. M. / Nilsson, S. C. / Groeneveld, T. W. / Villoutreix, B. O. / Blom, A. M. et al. | 2010
- 2257
-
The common C3F/S polymorphism, R102G, alters factor H regulation of the alternative pathway convertase and combines with other complement variants to influence complement activity in plasmaHeurich, M. / Martinez-Barricarte, R. / Francis, N. J. / Roberts, D. L. / de Cordoba, S. R. / Paul Morgan, B. / Harris, C. L. et al. | 2010
- 2257
-
Structural insights into the initiation of the terminal pathwayHadders, M. A. / Pangburn, M. K. / Svergun, D. I. / Gros, P. et al. | 2010
- 2257
-
Understanding the structural basis of convertase stability: Fine mapping of residues required for CVF-like activity in human C3/CVF hybrid proteinsHew, B. E. / Wong, K. / Lee, J. Q. / Pangburn, M. / Vogel, C. W. / Fritzinger, D. C. et al. | 2010
- 2258
-
Multiplex approach for evaluating the components of the complement systemBay, J. T. / Garred, P. et al. | 2010
- 2258
-
Characterizing the complement receptor Type 2-C3d complex by site-directed mutagenesis and molecular modelingStorek, M. J. / Holers, V. M. / Shaw, C. D. / Young, K. A. / Kovacs, J. M. / Thurman, J. M. / Hannan, J. P. et al. | 2010
- 2258
-
A new possible mechanism for target discrimination of the alternative pathway revealed by structural and functional studies of factor H domains 19-20 and C3dKajander, T. / Bhattacharjee, A. / Lehtinen, M. J. / Hyvarinen, S. / Leung, E. / Isenman, D. E. / Meri, S. / Goldman, A. / Sakari Jokiranta, T. et al. | 2010
- 2259
-
Crystal structure of C3bB in complex with factor DForneris, F. / Wu, J. / Wallace, R. S. / Tzekou, A. / Ricklin, D. / Lambris, J. D. / Gros, P. et al. | 2010
- 2259
-
Potent inhibition of the classical pathway of complement by a novel C1q-binding peptide derived from the human astrovirus coat proteinGronemus, J. Q. / Hair, P. S. / Crawford, K. B. / Cunnion, K. M. / Krishna, N. K. et al. | 2010
- 2259
-
Characterization of the interactions between C3b and complement regulatorsWu, J. / Ricklin, D. / Sfyroera, G. / Tzekou, A. / Atkinson, J. P. / Lambris, J. D. / Gros, P. et al. | 2010
- 2260
-
Inflammation and joint disease: Molecules/fragments that are released upon cartilage breakdown can activate complement and provide a new diagnostics for pathological complement activationHapponen, K. E. / Saxne, T. / Aspberg, A. / Morgelin, M. / Heinegard, D. / Blom, A. M. et al. | 2010
- 2260
-
Enhancement of heparin binding of factor H domains 19-20 with multiple point mutationsHyvarinen, S. / Lehtinen, M. J. / Rops, A. / van der Vlag, J. / Jokiranta, T. S. et al. | 2010
- 2260
-
Mutational analysis of ligand-binding activities of recombinant gC1q heterotrimerGadjeva, M. / Zlatarova, A. / Ruseva, M. / Kishore, U. / Kojouharova, M. et al. | 2010
- 2261
-
Building up a picture of C7 on the basis of high-resolution structure of its component modulesClark, C. / Phelan, M. / Ford, S. / Ogata, R. / Bramham, J. / Barlow, P. N. et al. | 2010
- 2261
-
Biophysical investigations of complement receptor 2 (CR2, CD21) ligand interactions reveal specific amino acid contacts unique to each receptor-ligand pairKovacs, J. M. / Eisenmesser, E. Z. / Hannan, J. P. / Holers, V. M. et al. | 2010
- 2262
-
Progress on solving high-resolution 3D structure of site 1 of complement receptor type 1Guariento, M. / Bella, J. / Schmidt, C. Q. / Hauhart, R. / Allen, T. / Atkinson, J. P. / Barlow, P. N. et al. | 2010
- 2262
-
TED and CUB domain movements between complement C3 and C3u by constrained X-ray scattering modelling provide insight into C3 activationLi, K. / Gor, J. / Perkins, S. J. et al. | 2010
- 2262
-
High-resolution structures of module pairs 10-11, 11-12 and 12-13 combined with SAXS data for 10-15 and 10-18 constructs to define architecture of factor HMakou, E. / Matis, I. / Schmidt, C. Q. / Mertens, H. D. / Svergun, D. / Barlow, P. N. et al. | 2010
- 2263
-
In-depth analysis by Biacore technology to evaluate the affinity versus avidity of the binding of the oligomeric pattern recognition molecule mannan-binding lectinGjelstrup, L. C. / Thiel, S. / Kingshott, P. / Thielens, N. / Vorup-Jensen, T. et al. | 2010
- 2263
-
Complement factor H binds at two independent sites to C-reactive protein in acute phase concentrationsOkemefuna, A. I. / Nan, R. / Miller, A. / Gor, J. / Perkins, S. J. et al. | 2010
- 2263
-
The His402 allotype of complement factor H show similar self-association to the Tyr402 allotype but exhibits greater self-association in the presence of zincNan, R. / Ward, G. / Gavigan, L. / Miller, A. / Gor, J. / Lengyel, I. / Perkins, S. J. et al. | 2010
- 2264
-
Oligomeric solution structures of factor H in the presence of heparin fragmentsKhan, S. / Miller, A. / Gor, J. / Mulloy, B. / Perkins, S. J. et al. | 2010
- 2264
-
Coordinate activation of the factor B scissile bond with the Mg(2+)-dependent c3b-binding site during assembly of the alternative pathway convertaseHourcade, D. E. / Mitchell, L. M. et al. | 2010
- 2264
-
Protection from complement-dependent cytotoxicity by NF-(B p65Gancz, D. / Fishelson, Z. et al. | 2010
- 2265
-
Trypanosoma cruzi calreticulin inhibits the complement lectin pathway activation by direct interaction with l-FicolinFerreira, A. / Ramirez, G. / Sanchez, G. / Ribeiro, C. H. / Lopez, N. / Maldonado, I. / Fujita, T. / Schwaeble, W. / Valck, C. et al. | 2010
- 2265
-
The substrate specificity of the complement initiating protease, C1rWijeyewickrema, L. C. / Tran, T. / Thompson, P. E. / Matthews, A. / Kaiserman, D. / Bird, P. / Pike, R. et al. | 2010
- 2265
-
Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4Duncan, R. C. / Wijeyewickrema, L. C. / Bergstrom, F. / Blom, A. M. / Pike, R. N. et al. | 2010
- 2266
-
Targeting complement inhibition to post-ischemic neoepitopes exposed in transplanted heartsAtkinson, C. / Yang, X. / Kulik, L. / Qiao, F. / Casey, S. / Holers, V. M. / Tomlinson, S. et al. | 2010
- 2266
-
Pathogenic natural IgM antibodies recognizing vascular post-ischemic neoepitopes initiate the inflammatory response important for both hepatic ischemia/reperfusion injury and liver regenerationHe, S. / Atkinson, C. / Morris, K. / Kulik, L. / Holers, V. M. / Tomlinson, S. et al. | 2010
- 2266
-
MBL/MASP-1 complexes efficiently cleave a zymogen of complement factor DTakahashi, M. / Iwaki, D. / Endo, Y. / Takahashi, K. / Stahl, G. L. / Fujita, T. et al. | 2010
- 2267
-
Targeted inhibition of the alternative pathway ameliorates progression of renal disease in murine models of systemic lupus erythematosusSekine, H. / Kinser, T. / Martinez, E. / Paulling, E. / Qiao, F. / Ruiz, P. / Gilkeson, G. / Tomlinson, S. et al. | 2010
- 2267
-
C3-/- mice are partially protected against Chlamydia psittaci in the early phase of lung infectionEbeling, J. / Dutow, P. / Janik, K. / Sommer, K. / Glage, S. / Tummler, B. / Munder, S. / Sachse, K. / Klos, A. et al. | 2010
- 2268
-
An inhibitory role of complement in monoclonal antibody therapy of lymphomaFritzinger, D. C. / Vogel, C. W. / Damaj, B. B. / Finnegan, P. W. et al. | 2010
- 2268
-
Upstream inhibition of key innate immune pathways in vivo in sepsisThorgersen, E. B. / Hellerud, B. C. / Nielsen, E. W. / Barratt-Due, A. / Fure, H. / Lindstad, J. K. / Pharo, A. / Fosse, E. / Tonnessen, T. I. / Johansen, H. T. et al. | 2010
- 2268
-
Pharmacokinetics of humanized cobra venom factor in miceFritzinger, D. C. / Damaj, B. B. / Wong, K. / Vogel, C. W. / Finnegan, P. W. et al. | 2010
- 2269
-
C5aR negatively regulates in vivo and in vitro production of IL-17AWard, P. A. / Bosmann, M. / Sarma, J. V. / Zhu, K. / Zetoune, F. S. et al. | 2010
- 2269
-
Essential role of complement MASP-1/3 in the murine collagen antibody-induced model of inflammatory arthritis 1Banda, N. K. / Takahashi, M. / Levitt, B. / Glogowska, M. / Nicholas, J. / Takahashi, K. / Stahl, G. L. / Fujita, T. / Arend, W. P. / Holers, V. M. et al. | 2010
- 2270
-
Dysregulation of the complement system in neurodegenerative diseaseWoodruff, T. M. / Lee, J. D. / Taylor, S. M. / Noakes, P. G. et al. | 2010
- 2270
-
The role of complement anaphylatoxin receptors in mesenteric ischemia/reperfusion-induced injuryWu, M. C. / Moore, T. A. / Manthey, H. D. / Taylor, S. M. / Woodruff, T. M. et al. | 2010
- 2270
-
Membrane complement regulators may protect against encapsular peritoneal sclerosis (EPS) in a chronic proliferative peritoneal inflammation model of zymosan peritonitis in the ratMizuno, M. / Ito, Y. / Mizuno, T. / Suzuki, Y. / Noda, Y. / Yamada, K. / Harris, C. L. / Okada, N. / Morgan, B. P. / Matsuo, S. et al. | 2010
- 2271
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Generation of a transgenic mouse expressing a human gain-of-function factor B mutation associated with atypical Hemolytic Uremic SyndromeMontes, T. / Blanco, L. / Vazquez-Martul, E. / Pinto, S. / Dominguez, M. / Morgan, B. P. / Harris, C. L. / Cordoba, S. R. et al. | 2010
- 2271
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Intraportally transplanted islet xenografts induce alternative complement pathway activation in non-human primate recipientKang, H. J. / Lee, H. / Ha, J. m. / Jin, S. M. / Kim, K. S. / Park, C. G. / Kim, S. J. et al. | 2010
- 2271
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Recombinant full-length factor H from Pichia pastoris-Building on fragmentary knowledgeSchmidt, C. Q. / Slingsby, F. / Guariento, M. / Mertens, H. D. / Svergun, D. I. / Richards, A. / Barlow, P. N. et al. | 2010
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Absence of MBL prevents hyperglycemic cardiovascular complicationsPavlov, V. I. / La Bonte, L. R. / Markiewski, M. M. / Lambris, J. D. / Stahl, G. L. et al. | 2010
- 2272
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The role of complement-mediated inflammation in miscarriage and preterm birthCostantini, K. J. / Coulthard, L. G. / Woodruff, T. M. / Taylor, S. M. / Callaway, L. K. et al. | 2010
- 2272
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Complement receptor 1-related gene/protein Crry deficiency contributes to the antigen specific recall response in experimental autoimmune myasthenia gravis (EAMG)Soltys, J. et al. | 2010
- 2273
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Decay accelerating factor is the primary protector of the neuromuscular junction from complement damageKusner, L. / Montresor-Lopez, J. / Kaminski, H. et al. | 2010
- 2273
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N2 peptide blocks natural IgM-mediated injury in a murine model of myocardial infarctionHaas, M. / Schuerpf, F. / Alicot-Carroll, E. M. / Chiu, I. / Kim, K. / Sachs, D. / Carroll, M. C. et al. | 2010
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Complement deficiency leads to a prominent lymphoid nodule development in a Sendai virus-induced mouse model of asthmaWu, X. / Micka, W. S. / Mao, D. / Kolar, G. / Zhang, Y. / Holtzman, M. J. / Atkinson, J. P. et al. | 2010
- 2274
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The contribution of the component C5 in fatty liver disease: A murine modelBavia, L. / Isaac, L. et al. | 2010
- 2274
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Greater C5a generation in the BUB/BnJ mouse: Designing better mouse models to study the role of complement in degenerative diseasesCole, T. A. / Pisalyaput, K. / Benoit, M. E. / Rowther, N. / Tenner, A. J. et al. | 2010
- 2274
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Interactions between complement and neutrophil extracellular trapsLeffler, J. / Martin, M. / Blom, A. M. et al. | 2010
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The onset of reperfusion injury: Deposition of antibodies and complement in viable myocardium in a porcine model of acute coronary syndromeKamat, P. / Broillet, A. / Helbert, A. / Bettinger, T. / Tranquart, F. / Schneider, M. / Rieben, R. et al. | 2010
- 2275
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DAF deficiency is protective during atherosclerosis in apoE deficient miceLewis, D. / Jackson, C. L. / Perry, M. J. / Morgan, B. P. / Hughes, T. R. et al. | 2010
- 2275
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Complement activation in preterm delivery in miceGonzalez, J. M. / Franzke, C. V. / Romero, R. / Girardi, G. et al. | 2010
- 2276
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Comparison of expression profiles from wildtype and C6 deficient peripheral nerves after crush injurySta, M. / Fluiter, K. / Ramaglia, V. / Wolterman, R. / Morgan, B. P. / Baas, F. et al. | 2010
- 2276
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Inhibition of complement activation prevents features of preeclampsia in a mouse modelGelber, S. E. / Redecha, P. B. / Tomlinson, S. / Davisson, R. L. / Salmon, J. E. et al. | 2010
- 2277
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Mice lacking the C3a receptor (C3aR) are susceptible to Listeria monocytogenes systemic infection despite having an elevated CD^4^+ Th1 cytokine responseMueller-Ortiz, S. L. / Morales, J. E. / Wetsel, R. A. et al. | 2010
- 2277
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Accelerated development of lupus nephritis in MRL-lpr mice lacking complement factor HBao, L. / Haas, M. / Quigg, R. J. et al. | 2010
- 2277
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CR2 targeted complement inhibitors attenuate intestinal damageFleming, S. D. / Hylton, D. / Hoffman, S. / Pope, M. / Tomlinson, S. et al. | 2010
- 2277
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Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytesAlexander, J. J. / Finberg, R. W. / Quigg, R. J. et al. | 2010
- 2278
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Ultrastructural characterization of C3 and C4 deposition during atherosclerosisShields, K. J. / Santelices, L. C. / Stolz, D. / Watkins, S. C. / Ahearn, J. M. et al. | 2010
- 2278
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Study of complement activation by liposomes of different lipid composition as potential drug-carriersLandi-Librandi, A. P. / Chrysostomo, T. N. / Azzolini, A. E. / Oliveira, C. A. / Marzocchi-Machado, C. M. / Lucisano-Valim, Y. M. et al. | 2010
- 2278
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Applicability of a kinetic microassay to evaluate modulation of the human complement system activity by snake venomsAyres, L. R. / Recio, A. D. / Azzolini, A. E. / Soares, A. M. / Sampaio, S. V. / Assis-Pandochi, A. I. / Pereira-Crott, L. S. et al. | 2010
- 2279
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Bifunctional lipocalin inhibitor of C5 and leukotriene B4 is protective in experimental immune complex alveolitisNunn, M. A. / Roversi, P. / Maillet, I. / Ahmat, N. / Togbe, D. / Quesniaux, V. F. / Teixeira, M. / Lissina, O. / Boland, W. / Ploss, K. et al. | 2010
- 2279
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Serum M-ficolin in children with cancerSchlapbach, L. J. / Thiel, S. / Aebi, C. / Hirt, A. / Leibundgut, K. / Jensenius, J. C. / Ammann, R. A. et al. | 2010
- 2280
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Successful treatment of acute angioedema attacks with a bradykinin receptor-2 antagonist (Icatibant) in a patient with acquired C1 inhibitor deficiencyZanichelli, A. / Badini, M. / Nataloni, I. / Cicardi, M. et al. | 2010
- 2280
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Residual disease in patients with angioedema due to hereditary C1 inhibitor deficiency and access to established therapy: A 21 months prospective study in a cohort of 103 patientsZanichelli, A. / Vacchini, R. / Badini, M. / Nataloni, I. / Cicardi, M. et al. | 2010
- 2280
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An old enigma revisited: Clinical course of hereditary angioedema is genetically determinedFust, G. / Farkas, H. / Varga, L. / Csuka, D. / Szilagyi, A. et al. | 2010
- 2281
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Effects of anti-modified C-reactive protein autoantibodies from patients with lupus nephritis on the interaction between modified C-reactive protein and complementsTan, Y. / Yu, F. / Wang, F. m. / Zhao, M. h. et al. | 2010
- 2281
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Characterizing kidney and eye pathology of complement factor H deficient miceLiao, S. M. / Buchanan, N. / Demirs, J. / Anderson, K. / Jaffee, B. D. et al. | 2010
- 2281
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Autonomic nervous system in the pathogenesis of angioedema due to C1 inhibitor deficiencyZanichelli, A. / Badini, M. / Casella, F. / Montano, N. / Cicardi, M. et al. | 2010
- 2282
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Complement and non-alcoholic liver disease: Role of C4 and C1q in diet-induced obesity in miceHillian, A. D. / Sebastian, B. M. / Nagy, L. E. et al. | 2010
- 2282
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Thrombospondin-1 receptors regulate leukocyte chemotactic response to C5a/C5a des ArgGe, L. / Trujillo, G. / Zhang, J. / Kew, R. R. et al. | 2010
- 2282
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Changes in anti-C1q IgG levels neither forecast nor mark a lupus nephritis flareBitter, J. / Dials, S. / Nagaraja, H. N. / Yu, C. Y. / Rovin, B. H. / Hebert, L. A. / Birmingham, D. J. et al. | 2010
- 2283
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Complement regulator CD59 protects against angiotensin II-induced abdominal aortic aneurysms in miceWu, G. / Chen, T. / Hu, W. / Shi, G. P. / Aktas, H. / Halperin, J. A. / Qin, X. et al. | 2010
- 2283
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C4B*Q synergizes with smoking to precipitate chronic obstructive pulmonary diseaseBjornsson, E. T. / Einarsdottir, K. / Benediktsdottir, B. / Gudmundsson, G. / Gislason, T. / Arason, G. J. et al. | 2010
- 2283
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High throughput screening of small molecule inhibitors of human alternative pathway complementKimura, Y. / Chiu, C. H. / Napper, A. D. / Diamond, S. L. / Song, W. C. et al. | 2010
- 2284
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Effects of single-nucleotide polymorphisms in a lupus-associated haplotype of complement receptor 2 on alternative splicingLough, K. M. / Douglas, K. B. / Homme, C. L. / Ulgiati, D. / Tsao, B. P. / Boackle, S. A. et al. | 2010
- 2284
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Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosisKourtzelis, I. / Markiewski, M. M. / Doumas, M. / Rafail, S. / Kambas, K. / Mitroulis, I. / Panagoutsos, S. / Passadakis, P. / Vargemezis, V. / Magotti, P. et al. | 2010
- 2284
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Recombinant forms of monomeric and homotrimeric globular regions of human C1q as inhibitors of complement and microglia activation induced by beta-amyloid and familial dementia peptidesNayak, A. / Waters, P. / Gadjeva, M. / Ferluga, J. / Reid, K. B. / Sim, R. B. / Tsolaki, A. / Kishore, U. et al. | 2010
- 2285
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Two N-terminal factor H mutations linked to aHUS cause defects in fluid-phase and cell-surface complement regulatory functionsPechtl, I. / Kavanagh, D. / Harris, C. / Barlow, P. N. et al. | 2010
- 2285
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Low gene copy-number of complement C4A, the presence of HLA-DR3, and the presence of HLA-DR2 are independent and additive risk factors for human systemic lupus erythematosusWu, Y. L. / Lundstrom, E. / Liu, C. C. / Yang, Y. / Gunnarsson, I. / Svenungsson, E. / Zhou, B. / Jones, K. N. / Nagaraja, H. N. / Higgins, G. C. et al. | 2010
- 2286
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A novel hybrid complement gene associated with familial haemolytic uraemic syndromeFrancis, N. J. / Harris, C. / McNicholas, B. / Awan, A. / Reddan, D. / Sadlier, D. / Kavanagh, D. / Strain, L. / Marchbank, K. J. / Goodship, T. H. et al. | 2010
- 2286
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Complement C4d deposition on circulating blood cells: Mechanisms and implication in systemic lupus erythematosus (SLE)Liu, C. C. / Kao, A. H. / Navratil, J. S. / Manzi, S. / Ahearn, J. M. et al. | 2010
- 2286
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Complement activation induced modification of the vitamin D binding proteinRamadass, M. / Kew, R. R. et al. | 2010
- 2287
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Recruitment of human endothelial cells expressing alpha-gal epitopes into tumor vessels as a novel strategy to promote complement dependent tumor regressionMacor, P. / Mezzaroba, N. / Bossi, F. / Biffi, F. / Zorzet, S. / Garrovo, C. / Tedesco, F. et al. | 2010
- 2287
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Development of human bispecific antibodies against CD20/CD55 or CD20/CD59 for the treatment of Burkitt lymphomaMacor, P. / Secco, E. / Mezzaroba, N. / De Maso, L. / Durigutto, P. / Gaiotto, T. / Garrovo, C. / Biffi, F. / Zorzet, S. / Sblattero, D. et al. | 2010
- 2287
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Complement deficiency ameliorates cigarette smoke induced lung injuryCasey, S. / Qiao, F. / Elvington, A. / Tomlinson, S. / Atkinson, C. et al. | 2010
- 2288
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Complement mediated endothelial cell (ECs) activation in a swine model of renal ischemia/reperfusion (I/R) injuryGiuseppe, C. / Claudia, C. / Tiziana, T. / Giuseppe, D. P. / Fabio, S. / Rita, M. / Antonia, L. / Pasquale, D. / Giuseppe, L. / Michele, B. et al. | 2010
- 2288
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Complement pathway activation and regulation during osteoarthritis progressionScott, J. L. / Scanzello, C. R. / Crow, M. K. et al. | 2010
- 2289
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Generation of analogues of the clinical complement inhibitor compstatin with improved potency and pharmacokineticsQu, H. / Magotti, P. / Ricklin, D. / Wu, E. L. / Kourtzelis, I. / Lasaosa, M. / Wu, Y. Q. / Lupu, F. / Kaznessis, Y. N. / Lambris, J. D. et al. | 2010
- 2289
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Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of E. coli sepsisLupu, F. / Silasi-Mansat, R. / Zhu, H. / Popescu, N. I. / Peer, G. / Sfyroera, G. / Magotti, P. / Ivanciu, L. / Lupu, C. / Mollnes, T. E. et al. | 2010
- 2289
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Impaired ability of complement activation via the alternative pathway C3 convertase caused by a single-point mutation in the beta chain of C3Sfyroera, G. / Ricklin, D. / Chen, H. / Nilsson-Ekdahl, K. / Nilsson, B. / Wu, E. L. / Kaznessis, Y. N. / Lambris, J. D. et al. | 2010
- 2290
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Cofactor amplification of C5a/C5a des Arg chemotactic activity in physiological fluidsHabiel, D. M. / Trujillo, G. / Zhang, J. / Kew, R. R. et al. | 2010
- 2290
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Identification and characterisation of C5a-inhibiting biostable aptamersVater, A. / Jarosch, F. / Purschke, W. / Reutter, R. / Maasch, C. / Buchner, K. / Eulberg, D. / Huber-Lang, M. / Klussmann, S. et al. | 2010
- 2291
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Factor H autoantibodies are associated with MPGNPappworth, I. Y. / Denton, M. / Kavanagh, D. / Moore, I. / Strain, L. / Barlow, P. N. / Herbert, A. P. / Schmidt, C. Q. et al. | 2010
- 2291
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Factor I autoantibodies are associated with atypical haemolytic uraemic syndromeKavanagh, D. / Pappworth, I. Y. / Roversi, P. / Tapson, J. S. / Moore, I. / Strain, L. / Lea, S. / Goodship, T. H. / Marchbank, K. J. et al. | 2010
- 2291
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Functional characterization of mutations in complement C3 that predispose to aHUSMiller, E. C. / Roumenina, L. / Fremeaux-Bacchi, V. / Atkinson, J. P. et al. | 2010
- 2292
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The monoclonal antibody, 3E7, is a multi-functional inhibitor of the alternative pathway that blocks NeF-triggered activationPaixao-Cavalcante, D. / Lindorfer, M. A. / Morgan, B. P. / Taylor, R. P. / Harris, C. L. et al. | 2010
- 2292
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The complement inhibitor Crry is critical for the prevention of complement activation on murine renal tubular epithelial cellsRenner, B. / Coleman, K. E. / Amura, C. / Molina, H. / Holers, V. M. / Thurman, J. M. et al. | 2010
- 2292
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Non-invasive assessment of disease activity in a model of lupus nephritis using complement receptor-2 conjugated to superparamagnetic iron oxide nanoparticlesHasebroock, K. M. / Serkova, N. J. / Sargsyan, S. A. / Renner, B. / Larsen, B. / Stoldt, C. / Holers, V. M. / Thurman, J. M. et al. | 2010
- 2293
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Innate immune proteins C1q and MBL modulate clearance and metabolism of modified lipoproteins by human monocytes and macrophagesFraser, D. A. et al. | 2010
- 2293
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Acquired and hereditary complement abnormalities in atypical hemolytic and uremic syndrome and membranoproliferative glomerulonephritisFremeaux-Bacchi, V. / Roumenina, L. T. / Servais, A. / Dragon-Durey, M. A. / Loirat, C. et al. | 2010
- 2293
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Sensitive and specific assays for C3 nephritic factors permit dissection of mechanisms underlying complement dysregulationPaixao-Cavalcante, D. / Lopez-Trascasa, M. / Skattum, L. / Giclas, P. C. / Goodship, T. H. / Truedsson, L. / de Cordoba, S. R. / Morgan, B. P. / Harris, C. L. et al. | 2010
- 2294
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An immunoassay for the quantitation of complement fragment Ba in vitrode Forest, N. / Shaw, K. / Duncan, C. / Baker, D. / Bao, Q. / Sexton, P. et al. | 2010
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Editorial Board| 2010