Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor Strategy (Unknown)
- New search for: Becker, Katja
- New search for: Herold-Mende, Christel
- New search for: Park, Jenny J.
- New search for: Lowe, Gordon
- New search for: Schirmer, R. Heiner
- New search for: Becker, Katja
- New search for: Herold-Mende, Christel
- New search for: Park, Jenny J.
- New search for: Lowe, Gordon
- New search for: Schirmer, R. Heiner
In:
Journal of Medicinal Chemistry
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44
, 17
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2784-2792
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2001
- Article (Journal) / Electronic Resource
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Title:Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor Strategy
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Additional title:J. Med. Chem.
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Contributors:Becker, Katja ( author ) / Herold-Mende, Christel ( author ) / Park, Jenny J. ( author ) / Lowe, Gordon ( author ) / Schirmer, R. Heiner ( author )
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Published in:Journal of Medicinal Chemistry ; 44, 17 ; 2784-2792
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Publisher:
- New search for: American Chemical Society
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Publication date:2001-08-16
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Source:
Table of contents – Volume 44, Issue 17
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2679
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The First Potent and Selective Inhibitors of the Glycine Transporter Type 2Caulfield, Wilson L. / Collie, Iain T. / Dickins, Rachel S. / Epemolu, Ola / McGuire, Ross / Hill, David R. / McVey, Gillian / Morphy, J. Richard / Rankovic, Zoran / Sundaram, Hardy et al. | 2001
- 2683
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Discovery of Estrogen Sulfotransferase Inhibitors from a Purine Library ScreenVerdugo, Dawn E. / Cancilla, Mark T. / Ge, Xue / Gray, Nathanael S. / Chang, Young-Tae / Schultz, Peter G. / Negishi, Masahiko / Leary, Julie A. / Bertozzi, Carolyn R. et al. | 2001
- 2687
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Identification of the First trans-(3R,4R)- Dimethyl-4-(3-hydroxyphenyl)piperidine Derivative To Possess Highly Potent and Selective Opioid κ Receptor Antagonist ActivityThomas, James B. / Atkinson, Robert N. / Rothman, Richard B. / Fix, Scott E. / Mascarella, S. Wayne / Vinson, N. Ariane / Xu, Heng / Dersch, Christina M. / Lu, Y. -F. / Cantrell, Buddy E. et al. | 2001
- 2687
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Identification of the First trans-(3R,4R)- Dimethyl-4-(3-hydroxyphenyl)piperidine Derivative To Possess Highly Potent and Selective Opioid k Receptor Antagonist ActivityThomas, J.B. et al. | 2001
- 2691
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Rationally Based Efficacy Tuning of Selective Dopamine D4 Receptor Ligands Leading to the Complete Antagonist 2-[4-(4-Chlorophenyl)piperazin-1- ylmethyl]pyrazolo[1,5-a]pyridine (FAUC 213)Löber, Stefan / Hübner, Harald / Utz, Wolfgang / Gmeiner, Peter et al. | 2001
- 2695
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Sorbitol Dehydrogenase Inhibitors (SDIs): A New Potent, Enantiomeric SDI, 4-[2-1R-Hydroxy-ethyl)-pyrimidin-4-yl]-piperazine-1-sulfonic Acid DimethylamideMylari, Banavara L. / Oates, Peter J. / Beebe, David A. / Brackett, Nathaniel S. / Coutcher, James B. / Dina, Michael S. / Zembrowski, William J. et al. | 2001
- 2701
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3-Phenyl-5-acyloxymethyl-2H,5H-furan-2-ones: Synthesis and Biological Activity of a Novel Group of Potential Antifungal Drugs †Pour, Milan / Špulák, Marcel / Buchta, Vladimír / Kubanová, Petra / Vopršalová, Marie / Wsól, Vladimír / Fáková, Helena / Koudelka, Petr / Pourová, Hana / Schiller, Radan et al. | 2001
- 2707
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Design, Synthesis, and Structure−Activity Relationships of a Series of 3-[2-(1-Benzylpiperidin-4-yl)ethylamino]pyridazine Derivatives as Acetylcholinesterase InhibitorsContreras, Jean-Marie / Parrot, Isabelle / Sippl, Wolfgang / Rival, Yveline M. / Wermuth, Camille G. et al. | 2001
- 2719
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6-Substituted-4-(3-bromophenylamino)quinazolines as Putative Irreversible Inhibitors of the Epidermal Growth Factor Receptor (EGFR) and Human Epidermal Growth Factor Receptor (HER-2) Tyrosine Kinases with Enhanced Antitumor ActivityTsou, Hwei-Ru / Mamuya, Nellie / Johnson, Bernard D. / Reich, Marvin F. / Gruber, Brian C. / Ye, Fei / Nilakantan, Ramaswamy / Shen, Ru / Discafani, Carolyn / DeBlanc, Ronald et al. | 2001
- 2735
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Fluorosulfonyl- and Bis-(b-chloroethyl)amino-phenylamino Functionalized Pyrazolo(4,3-e)1,2,4-triazolo(1,5-c)pyrimidine Derivatives: Irreversible Antagonists at the Human A3 Adenosine Receptor and Molecular Modeling StudiesBaraldi, P.G. et al. | 2001
- 2735
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Fluorosulfonyl- and Bis-(β-chloroethyl)amino-phenylamino Functionalized Pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine Derivatives: Irreversible Antagonists at the Human A3 Adenosine Receptor and Molecular Modeling StudiesBaraldi, Pier Giovanni / Cacciari, Barbara / Moro, Stefano / Romagnoli, Romeo / Ji, Xiao-duo / Jacobson, Kenneth A. / Gessi, Stefania / Borea, Pier Andrea / Spalluto, Giampiero et al. | 2001
- 2743
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Synthesis, Mechanism of Action, and Antiviral Activity of a New Series of Covalent Mechanism-Based Inhibitors of S-Adenosyl-l-Homocysteine HydrolaseGuillerm, Georges / Guillerm, Danielle / Vandenplas-Witkowki, Corinne / Rogniaux, Hélène / Carte, Nathalie / Leize, Emmanuelle / Van Dorsselaer, Alain / De Clercq, Erik / Lambert, Christine et al. | 2001
- 2753
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Development of Serine Protease Inhibitors Displaying a Multicentered Short (<2.3 Å) Hydrogen Bond Binding Mode: Inhibitors of Urokinase-Type Plasminogen Activator and Factor XaVerner, Erik / Katz, Bradley A. / Spencer, Jeffrey R. / Allen, Darin / Hataye, Jason / Hruzewicz, Witold / Hui, Hon C. / Kolesnikov, Aleksandr / Li, Yong / Luong, Christine et al. | 2001
- 2772
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Adaptive Neuro-Fuzzy Inference System: An Instant and Architecture-Free Predictor for Improved QSAR StudiesLoukas, Yannis L. et al. | 2001
- 2784
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Human Thioredoxin Reductase Is Efficiently Inhibited by (2,2‘:6‘,2‘ ‘-Terpyridine)platinum(II) Complexes. Possible Implications for a Novel Antitumor StrategyBecker, Katja / Herold-Mende, Christel / Park, Jenny J. / Lowe, Gordon / Schirmer, R. Heiner et al. | 2001
- 2793
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Toward the Design of Chemical Libraries for Mass Screening Biased against Mutagenic CompoundsLlorens, Oriol / Perez, Juan J. / Villar, Hugo O. et al. | 2001
- 2805
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Prediction of the Aroma Quality and the Threshold Values of Some Pyrazines Using Artificial Neural Networks §Wailzer, Bettina / Klocker, Johanna / Buchbauer, Gerhard / Ecker, Gerhard / Wolschann, Peter et al. | 2001
- 2814
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Methylated Analogues of Methyl (R)-4-(3,4-Dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as Highly Potent k-Receptor Agonists: Stereoselective Synthesis, Opioid-Receptor Affinity, Receptor Selectivity, and Functional StudiesSoukara, S. et al. | 2001
- 2814
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Methylated Analogues of Methyl (R)-4-(3,4-Dichlorophenylacetyl)- 3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate (GR-89,696) as Highly Potent κ-Receptor Agonists: Stereoselective Synthesis, Opioid-Receptor Affinity, Receptor Selectivity, and Functional StudiesSoukara, Stella / Maier, Christoph A. / Predoiu, Ursula / Ehret, Andreas / Jackisch, Rolf / Wünsch, Bernhard et al. | 2001
- 2827
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Synthesis and in Vitro and in Vivo Antimalarial Activity of New 4-Anilinoquinolines †Delarue, Sandrine / Girault, Sophie / Maes, Louis / Debreu-Fontaine, Marie-Ange / Labaeïd, Mehdi / Grellier, Philippe / Sergheraert, Christian et al. | 2001
- 2834
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Selective Activation of Mitomycin A by Thiols To Form DNA Cross-links and Monoadducts: Biochemical Basis for the Modulation of Mitomycin Cytotoxicity by the Quinone Redox PotentialPaz, Manuel M. / Das, Arunangshu / Palom, Yolanda / He, Qiao-Yun / Tomasz, Maria et al. | 2001
- 2843
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Synthesis of and a Comparative Study on the Inhibition of Muscle and Liver Glycogen Phosphorylases by Epimeric Pairs of d-Gluco- and d-Xylopyranosylidene-spiro-(thio)hydantoins and N-(d-Glucopyranosyl) AmidesSomsák, László / Kovács, László / Tóth, Marietta / Ősz, Erzsébet / Szilágyi, László / Györgydeák, Zoltán / Dinya, Zoltán / Docsa, Tibor / Tóth, Béla / Gergely, Pál et al. | 2001
- 2849
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Synthesis and Evaluation of 4-Fluoro-8-substituted-2,3,4,5-tetrahydro-1H-2-benzazapines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the a2-AdrenoceptorGrunewald, G.L. et al. | 2001
- 2849
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Synthesis and Evaluation of 4-Fluoro-8-substituted-2,3,4,5-tetrahydro-1H-2-benzazapines as Selective Inhibitors of Phenylethanolamine N-Methyltransferase versus the α2-AdrenoceptorGrunewald, Gary L. / Caldwell, Timothy M. / Li, Qifang / Criscione, Kevin R. et al. | 2001
- 2857
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Photochemical Synthesis of N-Arylbenzophenanthridine Selective Estrogen Receptor Modulators (SERMs)Grese, Timothy A. / Adrian, M. Dee / Phillips, D. Lynn / Shetler, Pamela K. / Short, Lorri L. / Glasebrook, Andrew L. / Bryant, Henry U. et al. | 2001