Predicting Pharmacokinetic Profiles Using in Silico Derived Parameters (Unknown)
- New search for: Hosea, Natalie A.
- New search for: Jones, Hannah M.
- New search for: Hosea, Natalie A.
- New search for: Jones, Hannah M.
In:
Molecular
Pharmaceutics
;
10
, 4
;
1207-1215
;
2013
- Article (Journal) / Electronic Resource
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Title:Predicting Pharmacokinetic Profiles Using in Silico Derived Parameters
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Additional title:Mol. Pharmaceutics
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Contributors:Hosea, Natalie A. ( author ) / Jones, Hannah M. ( author )
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Published in:Molecular Pharmaceutics ; 10, 4 ; 1207-1215
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Publisher:
- New search for: American Chemical Society
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Publication date:2013-04-01
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Keywords:
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Source:
Table of contents – Volume 10, Issue 4
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1151
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Predictive DMPK: In Silico ADME Predictions in Drug DiscoveryKenny, Jane R. et al. | 2013
- 1153
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Physicochemical and DMPK In Silico Models: Facilitating Their Use by Medicinal ChemistsOrtwine, Daniel F. / Aliagas, Ignacio et al. | 2013
- 1162
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Evolution of ADME Science: Where Else Can Modeling and Simulation Contribute?Smith, Dennis A. et al. | 2013
- 1171
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Role of Electrostatic Potential in the in Silico Prediction of Molecular Bioactivation and MutagenesisFord, Kevin A. et al. | 2013
- 1183
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Quantitative Structure–Activity Relationship Models That Stand the Test of TimeDavis, Andrew M. / Wood, David J. et al. | 2013
- 1191
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Application of In Silico, In Vitro and Preclinical Pharmacokinetic Data for the Effective and Efficient Prediction of Human PharmacokineticsGrime, Kenneth H. / Barton, Patrick / McGinnity, Dermot F. et al. | 2013
- 1207
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Predicting Pharmacokinetic Profiles Using in Silico Derived ParametersHosea, Natalie A. / Jones, Hannah M. et al. | 2013
- 1216
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The Contribution of Atom Accessibility to Site of Metabolism Models for Cytochromes P450Rydberg, Patrik / Rostkowski, Michal / Gloriam, David E. / Olsen, Lars et al. | 2013
- 1224
-
In Silico Physicochemical Parameter PredictionsWenlock, Mark C. / Barton, Patrick et al. | 2013
- 1236
-
Identification of Novel Breast Cancer Resistance Protein (BCRP) Inhibitors by Virtual ScreeningPan, Yongmei / Chothe, Paresh P. / Swaan, Peter W. et al. | 2013
- 1249
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Integration of in Silico and in Vitro Tools for Scaffold Optimization during Drug Discovery: Predicting P‑Glycoprotein EffluxDesai, Prashant V. / Sawada, Geri A. / Watson, Ian A. / Raub, Thomas J. et al. | 2013
- 1262
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Predicting Intrinsic Clearance for Drugs and Drug Candidates Metabolized by Aldehyde OxidaseJones, Jeffrey P. / Korzekwa, Kenneth R. et al. | 2013
- 1269
-
Receptor-Mediated Endocytosis across Human Placenta: Emphasis on MegalinAkour, Amal A. / Kennedy, Mary Jayne / Gerk, Phillip et al. | 2013
- 1279
-
Nanotechnology-Based Gene-Eluting StentsGoh, Debbie / Tan, Aaron / Farhatnia, Yasmin / Rajadas, Jayakumar / Alavijeh, Mohammad S. / Seifalian, Alexander M. et al. | 2013
- 1299
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Cationic alpha -Cyclodextrin:Poly(ethylene glycol) Polyrotaxanes for siRNA DeliveryKulkarni, A. / DeFrees, K. / Schuldt, R.A. / Hyun, S.-H. / Wright, K.J. / Yerneni, C.K. / VerHeul, R. / Thompson, D.H. et al. | 2013
- 1299
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Cationic α‑Cyclodextrin:Poly(ethylene glycol) Polyrotaxanes for siRNA DeliveryKulkarni, Aditya / DeFrees, Kyle / Schuldt, Ryan A. / Hyun, Seok-Hee / Wright, Kyle J. / Yerneni, Charu K. / VerHeul, Ross / Thompson, David H. et al. | 2013
- 1306
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Polyplex Exposure Inhibits Cell Cycle, Increases Inflammatory Response, and Can Cause Protein Expression without Cell DivisionMatz, Rebecca L. / Erickson, Blake / Vaidyanathan, Sriram / Kukowska-Latallo, Jolanta F. / Baker, James R. / Orr, Bradford G. / Banaszak Holl, Mark M. et al. | 2013
- 1318
-
In Silico Categorization of in Vivo Intrinsic Clearance Using Machine LearningHsiao, Ya-Wen / Fagerholm, Urban / Norinder, Ulf et al. | 2013
- 1322
-
Rapid Analysis of Antibody Self-Association in Complex Mixtures Using Immunogold ConjugatesSule, Shantanu V. / Dickinson, Craig D. / Lu, Jirong / Chow, Chi-Kin / Tessier, Peter M. et al. | 2013
- 1332
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Liquid–Liquid Miscibility Gaps in Drug–Water Binary Systems: Crystal Structure and Thermodynamic Properties of Prilocaine and the Temperature–Composition Phase Diagram of the Prilocaine–Water SystemRietveld, Ivo B. / Perrin, Marc-Antoine / Toscani, Siro / Barrio, Maria / Nicolai, Beatrice / Tamarit, Josep-Lluis / Ceolin, René et al. | 2013
- 1340
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Controlled Access of p53 to the Nucleus Regulates Its Proteasomal Degradation by MDM2Davis, James R. / Mossalam, Mohanad / Lim, Carol S. et al. | 2013
- 1350
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A Single Mutant, A276S of p53, Turns the Switch to ApoptosisReaz, Shams / Mossalam, Mohanad / Okal, Abood / Lim, Carol S. et al. | 2013
- 1360
-
Novel Molecular Platform Integrated Iron Chelation Therapy for 1H‑MRI Detection of β‑Galactosidase ActivityLi, Xiaojin / Zhang, Zhongwei / Yu, Zijun / Magnusson, Jennifer / Yu, Jian-Xin et al. | 2013
- 1360
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Novel Molecular Platform Integrated Iron Chelation Therapy for ^1H-MRI Detection of beta -Galactosidase ActivityLi, X. / Zhang, Z. / Yu, Z. / Magnusson, J. / Yu, J.-X. et al. | 2013
- 1368
-
Predicting the Complex Phase Behavior of Self-Assembling Drug Delivery NanoparticlesLe, Tu C. / Mulet, Xavier / Burden, Frank R. / Winkler, David A. et al. | 2013
- 1378
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Propylene Glycol-Linked Amino Acid/Dipeptide Diester Prodrugs of Oleanolic Acid for PepT1-Mediated Transport: Synthesis, Intestinal Permeability, and PharmacokineticsCao, Feng / Gao, Yahan / Wang, Meng / Fang, Lei / Ping, Qineng et al. | 2013
- 1388
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In Vitro to in Vivo Extrapolation and Physiologically Based Modeling of Cytochrome P450 Mediated Metabolism in Beagle Dog Gut Wall and LiverHeikkinen, Aki T. / Fowler, Stephen / Gray, Lynn / Li, Jia / Peng, Ying / Yadava, Preeti / Railkar, Aruna / Parrott, Neil et al. | 2013
- 1400
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Design and Evaluation of New Tc-99m-Labeled Lactam Bridge-Cyclized Alpha-MSH Peptides for Melanoma ImagingGuo, Haixun / Gallazzi, Fabio / Miao, Yubin et al. | 2013
- 1409
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Functional and Molecular Expression of the Proton-Coupled Oligopeptide Transporters in Spleen and Macrophages from Mouse and HumanSun, Dongli / Wang, Yuqing / Tan, Fuqing / Fang, Danbo / Hu, Yongjun / Smith, David E. / Jiang, Huidi et al. | 2013
- 1417
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Cytomegalovirus Protease Targeted Prodrug DevelopmentSabit, Hairat / Dahan, Arik / Sun, Jing / Provoda, Chester J. / Lee, Kyung-Dall / Hilfinger, John H. / Amidon, Gordon L. et al. | 2013
- 1425
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Pharmacokinetics and Brain Uptake of an IgG-TNF Decoy Receptor Fusion Protein Following Intravenous, Intraperitoneal, and Subcutaneous Administration in MiceSumbria, Rachita K. / Zhou, Qing-Hui / Hui, Eric Ka-Wai / Lu, Jeff Zhiqiang / Boado, Ruben J. / Pardridge, William M. et al. | 2013
- 1432
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Effective Elimination of Cancer Stem Cells by Magnetic HyperthermiaSadhukha, Tanmoy / Niu, Lin / Wiedmann, Timothy Scott / Panyam, Jayanth et al. | 2013
- 1442
-
Sulfation Patterns Determine Cellular Internalization of Heparin-Like PolysaccharidesRaman, Karthik / Mencio, Caitlin / Desai, Umesh R. / Kuberan, Balagurunathan et al. | 2013
- 1450
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Polyamine Transport by the Polyspecific Organic Cation Transporters OCT1, OCT2, and OCT3Sala-Rabanal, Monica / Li, Dan C. / Dake, Gregory R. / Kurata, Harley T. / Inyushin, Mikhail / Skatchkov, Serguei N. / Nichols, Colin G. et al. | 2013
- 1459
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Original Multivalent Copper(II)-Conjugated Phosphorus Dendrimers and Corresponding Mononuclear Copper(II) Complexes with Antitumoral ActivitiesEl Brahmi, Nabil / El Kazzouli, Saïd / Mignani, Serge M. / Essassi, El Mokhtar / Aubert, Geneviève / Laurent, Régis / Caminade, Anne-Marie / Bousmina, Mosto M. / Cresteil, Thierry / Majoral, Jean-Pierre et al. | 2013
- 1465
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Multifunctional Nanoparticles Based on a Single-Molecule Modification for the Treatment of Drug-Resistant CancerWang, Dun / Tang, Jingling / Wang, Yongjun / Ramishetti, Srinivas / Fu, Qiang / Racette, Kelly / Liu, Feng et al. | 2013