1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent (English)
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- New search for: Mansuri, Muzammil M.
- New search for: Ghazzouli, Ismail
- New search for: Chen, Ming S.
- New search for: Howell, Henry G.
- New search for: Brodfuehrer, Paul R.
- New search for: Benigni, Daniel A.
- New search for: Martin, John C.
- New search for: Mansuri, Muzammil M.
- New search for: Ghazzouli, Ismail
- New search for: Chen, Ming S.
- New search for: Howell, Henry G.
- New search for: Brodfuehrer, Paul R.
- New search for: Benigni, Daniel A.
- New search for: Martin, John C.
In:
Journal of Medicinal Chemistry
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30
, 5
;
867-871
;
1987
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ISSN:
- Article (Journal) / Electronic Resource
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Title:1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent
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Additional title:J. Med. Chem.
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Contributors:Mansuri, Muzammil M. ( author ) / Ghazzouli, Ismail ( author ) / Chen, Ming S. ( author ) / Howell, Henry G. ( author ) / Brodfuehrer, Paul R. ( author ) / Benigni, Daniel A. ( author ) / Martin, John C. ( author )
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Published in:Journal of Medicinal Chemistry ; 30, 5 ; 867-871
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Publisher:
- New search for: American Chemical Society
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Publication date:1987-05-01
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Source:
Table of contents – Volume 30, Issue 5
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 755
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Rational design of 4-[(methylsulfonyl)amino]benzamides as class III antiarrhythmic agentsLumma, William C. / Wohl, Ronald A. / Davey, David D. / Argentieri, Thomas M. / DeVita, Robert J. / Gomez, Robert P. / Jain, Vijay K. / Marisca, Anthony J. / Morgan, Thomas K. et al. | 1987
- 758
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Synthesis and biological activity of partially modified retro-inverso pseudopeptide derivatives of the C-terminal tetrapeptide of gastrinRodriguez, Marc / Dubreuil, Philibert / Bali, Jean Pierre / Martinez, Jean et al. | 1987
- 764
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Synthesis and pharmacological evaluation of a new class of 2-(2-aminothiazol-4-yl)-2-hydrazonoacetamido cephalosporinsBrandt, Alberto / Cerquetti, Marina / Corsi, G. Bruno / Pascucci, Giorgio / Simeoni, Antonio / Martelli, Paola / Valcavi, Umberto et al. | 1987
- 768
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The metabolism of carbamazepine in humans: steric course of the enzymic hydrolysis of the 10,11-epoxideBellucci, Giuseppe / Berti, Giancarlo / Chiappe, Cinzia / Lippi, Annalisa / Marioni, Franco et al. | 1987
- 773
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Synthesis and antiarrhythmic activity of new 3-[2-(.omega.-aminoalkoxy)phenoxy]-4-phenyl-3-buten-2-ones and related compoundsSalimbeni, Aldo / Manghisi, Elso / Fregnan, Giancarlo B. / Prada, Marco et al. | 1987
- 780
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Synthesis and antiarrhythmic properties of novel 3-selena-7-azabicyclo[3.3.1]nonanes and derivatives. Single-crystal x-ray diffraction analysis of 7-benzyl-3-selena-7-azabicyclo[3.3.1]nonan-9-one and 7-benzyl-3-selena-7-azabicyclo[3.3.1]nonane hydroperchlorateThompson, M. Daniel / Smith, Gary S. / Berlin, K. Darrell / Holt, Elizabeth M. / Scherlag, Benjamin J. / Van der Helm, Dick / Muchmore, Steven W. / Fidelis, Krzysztof A. et al. | 1987
- 788
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Flavones. 1. Synthesis and antihypertensive activity of (3-phenylflavonoxy)propanolamines without .beta.-adrenoceptor antagonismWu, E. S. C. / Cole, T. E. / Davidson, T. A. / Blosser, J. C. / Borrelli, A. R. / Kinsolving, C. R. / Milgate, T. E. / Parker, R. B. et al. | 1987
- 792
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Structure-activity relationship in PAF-acether. 3. Hydrophobic contribution to agonistic activityGodfroid, Jean Jacques / Broquet, Colette / Jouquey, Simone / Lebbar, Mariya / Heymans, Francoise / Redeuilh, Catherine / Steiner, Efroim / Michel, Elie / Coeffier, Eliane et al. | 1987
- 798
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Resolution, absolute stereochemistry, and enantioselective activity of nomifensine and hexahydro-1H-indeno[1,2-b]pyridinesKunstmann, Rudolf / Gerhards, Hermann / Kruse, Hansjoerg / Leven, Margret / Paulus, Erich F. / Schacht, Ulrich / Schmitt, Karl / Witte, Peter U. et al. | 1987
- 805
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6-Methyl-6-azabicyclo[3.2.1]octan-3.alpha.-ol 2,2-diphenylpropionate (azaprophen), a highly potent antimuscarinic agentCarroll, F. Ivy / Abraham, Philip / Parham, Karol / Griffith, Ronald C. / Ahmad, Ateeq / Richard, Michelle M. / Padilla, Felipe N. / Witkin, Jeffrey M. / Chiang, Peter K. et al. | 1987
- 810
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Synthesis of new heparinoids with high anticoagulant activityHatanaka, Kenichi / Yoshida, Takashi / Miyahara, Shintaro / Sato, Takahiro / Ono, Fujihiko / Uryu, Toshiyuki / Kuzuhara, Hiroyoshi et al. | 1987
- 814
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Synthesis and neuroleptic activity of a series of 1-[1-(benzo-1,4-dioxan-2-ylmethyl)-4-piperidinyl]benzimidazolone derivativesHenning, Rainer / Lattrell, Rudolf / Gerhards, Hermann J. / Leven, Margret et al. | 1987
- 820
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Synthesis and antiinflammatory and analgesic activity of 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acids. The 6-substituted compounds.Muchowski, Joseph M. / Cooper, Gary F. / Halpern, Otto / Koehler, Richard / Kluge, Arthur F. / Simon, Robert L. / Unger, Stefan H. / Van Horn, Albert R. / Wren, Douglas L. et al. | 1987
- 824
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Dihydropyridazinone cardiotonics: synthesis and inotropic activity of 5'-(1,4,5,6-tetrahydro-6-oxo-3-pyridazinyl)-spiro[cycloalkane-1,3'-[3H]indol]-2'(1'H)-onesRobertson, David W. / Krushinski, Joseph H. / Pollock, G. Don / Wilson, Harve / Kauffman, Raymond F. / Hayes, J. Scott et al. | 1987
- 829
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Estrogenic affinity labels: synthesis, irreversible receptor binding, and bioactivity of aziridine-substituted hexestrol derivativesZablocki, Jeffery A. / Katzenellenbogen, John A. / Carlson, Kathryn E. / Norman, M. J. / Katzenellenbogen, Benita S. et al. | 1987
- 839
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Synthesis, absolute configuration, and antibacterial activity of 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acidGerster, John F. / Rohlfing, Steve R. / Pecore, Sharon E. / Winandy, Richard M. / Stern, Richard M. / Landmesser, June E. / Olsen, Roger A. / Gleason, William B. et al. | 1987
- 843
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Potential antitumor agents. 51. Synthesis and antitumor activity of substituted phenazine-1-carboxamidesRewcastle, Gordon W. / Denny, William A. / Baguley, Bruce C. et al. | 1987
- 852
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Kinetics of solvolysis and muscarinic actions of a (2-bromoethyl)methylamino analog of oxotremorineRingdahl, Bjorn / Jenden, Donald J. et al. | 1987
- 855
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Relationships between DNA-binding kinetics and biological activity for the 9-aminoacridine-4-carboxamide class of antitumor agentsWakelin, Laurence P. G. / Atwell, Graham J. / Rewcastle, Gordon W. / Denny, William A. et al. | 1987
- 862
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Potential anti-AIDS drugs. 2',3'-Dideoxycytidine analogsKim, Chong Ho / Marquez, Victor E. / Broder, Samuel / Mitsuya, Hiroaki / Driscoll, John S. et al. | 1987
- 867
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1-(2-Deoxy-2-fluoro-.beta.-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agentMansuri, Muzammil M. / Ghazzouli, Ismail / Chen, Ming S. / Howell, Henry G. / Brodfuehrer, Paul R. / Benigni, Daniel A. / Martin, John C. et al. | 1987
- 871
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Structure-activity relationships in the 2-arylcarbapenem series. Synthesis of 1-methyl-2-arylcarbapenemsGuthikonda, Ravindra Nath / Cama, L. D. / Quesada, M. / Woods, M. F. / Salzmann, T. N. / Christensen, B. G. et al. | 1987
- 880
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Anticonvulsant O-alkyl sulfamates. 2,3:4,5-Bis-O-(1-methylethylidene)-.beta.-D-fructopyranose sulfamate and related compoundsMaryanoff, Bruce E. / Nortey, Samuel O. / Gardocki, Joseph F. / Shank, Richard P. / Dodgson, Susanna P. et al. | 1987
- 888
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Isozyme-specific enzyme inhibitors. 13. S-[5'(R)-['N-triphosphoamino)methyl]adenosyl]-L-homocysteine, a potent inhibitor of rat methionine adenosyltransferasesVrudhula, Vivekananda M. / Kappler, Francis / Hampton, Alexander et al. | 1987
- 894
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Antisecretory activity of human, dog, and rat metabolites of fenoctimineScott, Malcolm K. / Jacoby, Henry I. / Bonfilio, Antoinette C. / Corcoran, Thomas W. / Lopez, Iris S. et al. | 1987
- 900
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A quantitative structure-activity relationship analysis of some 4-aminodiphenyl sulfone antibacterial agents using linear free energy and molecular modeling methodsLopez de Compadre, Rosa L. / Pearlstein, R. A. / Hopfinger, A. J. / Seydel, J. K. et al. | 1987
- 906
-
Antimalarial drugs. 61. Synthesis and antimalarial effects of 4-[(7-chloro-4-quinolinyl)amino]-2-[(diethylamino)methyl]-6-alkylphenols and their N.omega.-oxidesKesten, Stephen J. / Johnson, Judith / Werbel, Leslie M. et al. | 1987
- 911
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Leukotriene receptor antagonists. 2. The [[(tetrazol-5-ylaryl)oxy]methyl]acetophenone derivativesDillard, Robert D. / Carr, F. Patrick / McCullough, Doris / Haisch, Klaus D. / Rinkema, Lynn E. / Fleisch, Jerome H. et al. | 1987
- 918
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Preparation and biological evaluation of a potential photoaffinity label for the prostaglandin H2/thromboxane A2 receptorArora, S. K. / Kattelman, E. J. / Lim, C. T. / Le Breton, G. C. / Venton, D. L. et al. | 1987
- 924
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Nucleosides. 141. Synthesis of 5-.beta.-D-ribofuranosylnicotinamide and its N-methyl derivative. The isosteric and isoelectronic analogs of nicotinamide nucleosideKabat, Marek M. / Pankiewicz, Krzysztof W. / Watanabe, Kyoichi A. et al. | 1987
- 927
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Reactive 5'-substituted 2',5'-dideoxyuridine derivatives as potential inhibitors of nucleotide biosynthesisElliott, Robert D. / Pruett, Pamela S. / Brockman, R. Wallace / Montgomery, John A. et al. | 1987
- 930
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N-Methyl derivatives of the 5-HT2 agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropaneGlennon, Richard A. / Titeler, Milt / Seggel, Mark / Lyon, Robert A. et al. | 1987
- 933
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Opioid agonist and antagonist activities of monofunctional nitrogen mustard analogs of .beta.-chlornaltrexamine (.beta.-CNA)Schoenecker, J. W. / Takemori, A. E. / Portoghese, P. S. et al. | 1987
- 936
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O-Carbamoylsalicylates: agents for modification of hemoglobinsParameswaran, Kumarapuram N. / Shi, Guey Yeh / Klotz, Irving M. et al. | 1987
- 939
-
Imidazole anticonvulsants: structure-activity relationships of [(biphenylyloxy)alkyl]imidazolesRobertson, David W. / Beedle, E. E. / Lawson, Ron / Leander, J. David et al. | 1987
- 943
-
Synthesis and biological activity of unsaturated carboacyclic purine nucleoside analogsHaines, David R. / Tseng, Christopher K. H. / Marquez, Victor E. et al. | 1987
- 947
-
Hexahydro-1H-1-pyrindines from acid rearrangement of 9-alkylidene-5-(m-methoxyphenyl)-2-methylmorphans. Structural type of narcotic antagonistsAwaya, Hiroyoshi / May, Everette L. / Aceto, Mario D. / Harris, Louis S. / Silverton, James V. / Rice, Kenner C. / Mattson, Mariena V. / Jacobson, Arthur E. et al. | 1987
- 951
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Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 3. GuanidinesChapleo, Christopher B. / Myers, Peter L. / Smith, Alan C. B. / Tulloch, Ian F. / Walter, Donald S. et al. | 1987
- 954
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N6-Phenyladenosines: pronounced effect of phenyl substituents on affinity for A2 adenosine receptorsKwatra, Madan M. / Leung, Edward / Hosey, M. Marlene / Green, Richard D. et al. | 1987
- 956
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Book Reviews| 1987
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Masthead| 1987