Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies (Unknown)
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In:
Journal of Medicinal Chemistry
;
41
, 15
;
2806-2818
;
1998
- Article (Journal) / Electronic Resource
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Title:Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies
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Additional title:J. Med. Chem.
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Contributors:Dragovich, Peter S. ( author ) / Webber, Stephen E. ( author ) / Babine, Robert E. ( author ) / Fuhrman, Shella A. ( author ) / Patick, Amy K. ( author ) / Matthews, David A. ( author ) / Lee, Caroline A. ( author ) / Reich, Siegfried H. ( author ) / Prins, Thomas J. ( author ) / Marakovits, Joseph T. ( author )
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Published in:Journal of Medicinal Chemistry ; 41, 15 ; 2806-2818
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Publisher:
- New search for: American Chemical Society
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Publication date:1998-07-16
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Source:
Table of contents – Volume 41, Issue 15
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2663
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d-Amino Acid Containing, High-Affinity Inhibitors of Recombinant Human Calpain I †Chatterjee, Sankar / Gu, Zi-Qiang / Dunn, Derek / Tao, Ming / Josef, Kurt / Tripathy, Rabindranath / Bihovsky, Ron / Senadhi, Shobha E. / O'Kane, Teresa M. / McKenna, Beth Ann et al. | 1998
- 2667
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Enhancement of Oral Absorption in Selective 5-HT1D Receptor Agonists: Fluorinated 3-[3-(Piperidin-1-yl)propyl]indolesCastro, José L. / Collins, Ian / Russell, Michael G. N. / Watt, Alan P. / Sohal, Bindi / Rathbone, Denise / Beer, Margaret S. / Stanton, Josephine A. et al. | 1998
- 2671
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Novel and Specific Respiratory Syncytial Virus Inhibitors That Target Virus FusionDing, Wei-dong / Mitsner, Boris / Krishnamurthy, Girija / Aulabaugh, Ann / Hess, Cynthia D. / Zaccardi, Joe / Cutler, Mark / Feld, Boris / Gazumyan, Anna / Raifeld, Yuri et al. | 1998
- 2676
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Nucleosides and Nucleotides. 177. 9-(6,7-Dideoxy-b-D-allo-hept-5-ynofuranosyl)adenine: A Selective and Potent Ligand for P3 Purinoceptor-like ProteinMatsuda, Akira et al. | 1998
- 2676
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Nucleosides and Nucleotides. 177. 9-(6,7-Dideoxy-β-d-a llo-hept-5- ynofuranosyl)adenine: A Selective and Potent Ligand for P3 Purinoceptor-like ProteinMatsuda, Akira / Kosaki, Haruyo / Saitoh, Yoshiko / Yoshimura, Yuichi / Minakawa, Noriaki / Nakata, Hiroyasu et al. | 1998
- 2679
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Design, Synthesis, and Biological Activities of Potent and Selective Somatostatin Analogues Incorporating Novel Peptoid ResiduesTran, Thuy-Anh / Mattern, Ralph-Heiko / Afargan, Michel / Amitay, Oved / Ziv, Ofer / Morgan, Barry A. / Taylor, John E. / Hoyer, Daniel / Goodman, Murray et al. | 1998
- 2686
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Conformational Analyses of Somatostatin-Related Cyclic Hexapeptides Containing Peptoid ResiduesMattern, Ralph-Heiko / Tran, Thuy-Anh / Goodman, Murray et al. | 1998
- 2693
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Structure−Function Studies on Positions 17, 18, and 21 Replacement Analogues of Glucagon: The Importance of Charged Residues and Salt Bridges in Glucagon Biological Activity †Sturm, Noel S. / Lin, Ying / Burley, Stephen K. / Krstenansky, John L. / Ahn, Jung-Mo / Azizeh, Bassem Y. / Trivedi, Dev / Hruby, Victor J. et al. | 1998
- 2701
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Synthesis and in Vitro Efficacy of Transferrin Conjugates of the Anticancer Drug ChlorambucilBeyer, Ulrich / Roth, Thomas / Schumacher, Peter / Maier, Gerhard / Unold, Anuschka / Frahm, August W. / Fiebig, Heinz H. / Unger, Clemens / Kratz, Felix et al. | 1998
- 2709
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Synthesis and Evaluation of a Series of Novel 2-[(4-Chlorophenoxy)methyl]- benzimidazoles as Selective Neuropeptide Y Y1 Receptor AntagonistsZarrinmayeh, Hamideh / Nunes, Anne M. / Ornstein, Paul L. / Zimmerman, Dennis M. / Arnold, M. Brian / Schober, Douglas A. / Gackenheimer, Susan L. / Bruns, Robert F. / Hipskind, Philip A. / Britton, Thomas C. et al. | 1998
- 2720
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Indolequinone Antitumor Agents: Reductive Activation and Elimination from (5-Methoxy-1-methyl-4,7-dioxoindol-3-yl)methyl Derivatives and Hypoxia-Selective Cytotoxicity in VitroNaylor, Matthew A. / Swann, Elizabeth / Everett, Steven A. / Jaffar, Mohammed / Nolan, John / Robertson, Naomi / Lockyer, Stacey D. / Patel, Kantilal B. / Dennis, Madeleine F. / Stratford, Michael R. L. et al. | 1998
- 2732
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Selective Endothelin A Receptor Antagonists. 3. Discovery and Structure−Activity Relationships of a Series of 4-Phenoxybutanoic Acid DerivativesAstles, Peter C. / Brealey, Clive / Brown, Thomas J. / Facchini, Vincenzo / Handscombe, Caroline / Harris, Neil V. / McCarthy, Clive / McLay, Iain M. / Porter, Barry / Roach, Alan G. et al. | 1998
- 2745
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Selective Endothelin A Receptor Antagonists. 4. Discovery and Structure−Activity Relationships of Stilbene Acid and Alcohol Derivatives −Astles, Peter C. / Brown, Thomas J. / Halley, Frank / Handscombe, Caroline M. / Harris, Neil V. / McCarthy, Clive / McLay, Iain M. / Lockey, Peter / Majid, Tahir / Porter, Barry et al. | 1998
- 2754
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Antihyperglycemic Activities of Cryptolepine Analogues: An Ethnobotanical Lead Structure Isolated from Cryptolepis sanguinolenta †Bierer, Donald E. / Dubenko, Larisa G. / Zhang, Pingsheng / Lu, Qing / Imbach, Patricia A. / Garofalo, Albert W. / Phuan, Puay-Wah / Fort, Diana M. / Litvak, Joane / Gerber, R. Eric et al. | 1998
- 2765
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Synthesis and Pharmacological Characterization of Novel 6-Fluorochroman Derivatives as Potential 5-HT1A Receptor AntagonistsYasunaga, Tomoyuki / Kimura, Takenori / Naito, Ryo / Kontani, Toru / Wanibuchi, Fumikazu / Yamashita, Hiroshi / Nomura, Tamako / Tsukamoto, Shin-ichi / Yamaguchi, Tokio / Mase, Toshiyasu et al. | 1998
- 2779
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Preparation, Resolution, and Biological Evaluation of 5-Aryl-1,2-dihydro-5H-chromeno[3,4-f]quinolines: Potent, Orally Active, Nonsteroidal Progesterone Receptor AgonistsEdwards, James P. / Zhi, Lin / Pooley, Charlotte L. F. / Tegley, Christopher M. / West, Sarah J. / Wang, Ming-Wei / Gottardis, Marco M. / Pathirana, Charles / Schrader, William T. / Jones, Todd K. et al. | 1998
- 2786
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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric ReplacementsWebber, Stephen E. / Okano, Koji / Little, Thomas L. / Reich, Siegfried H. / Xin, Yue / Fuhrman, Shella A. / Matthews, David A. / Love, Robert A. / Hendrickson, Thomas F. / Patick, Amy K. et al. | 1998
- 2806
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity StudiesDragovich, Peter S. / Webber, Stephen E. / Babine, Robert E. / Fuhrman, Shella A. / Patick, Amy K. / Matthews, David A. / Lee, Caroline A. / Reich, Siegfried H. / Prins, Thomas J. / Marakovits, Joseph T. et al. | 1998
- 2819
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity StudiesDragovich, Peter S. / Webber, Stephen E. / Babine, Robert E. / Fuhrman, Shella A. / Patick, Amy K. / Matthews, David A. / Reich, Siegfried H. / Marakovits, Joseph T. / Prins, Thomas J. / Zhou, Ru et al. | 1998
- 2835
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Derivatives of the Triazoloquinazoline Adenosine Antagonist (CGS 15943) Having High Potency at the Human A2B and A3 Receptor SubtypesKim, Yong-Chul / de Zwart, Maarten / Chang, Louis / Moro, Stefano / von Frijtag Drabbe Künzel, Jacobien K. / Melman, Neli / IJzerman, Ad P. / Jacobson, Kenneth A. et al. | 1998
- 2846
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Styrylquinoline Derivatives: A New Class of Potent HIV-1 Integrase Inhibitors That Block HIV-1 Replication in CEM CellsMekouar, Khalid / Mouscadet, Jean-François / Desmaële, Didier / Subra, Frédéric / Leh, Hervé / Savouré, Delphine / Auclair, Christian / d'Angelo, Jean et al. | 1998
- 2858
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N-Phenylamidines as Selective Inhibitors of Human Neuronal Nitric Oxide Synthase: Structure−Activity Studies and Demonstration of in Vivo ActivityCollins, Jon L. / Shearer, Barry G. / Oplinger, Jeffrey A. / Lee, Shuliang / Garvey, Edward P. / Salter, Mark / Duffy, Claire / Burnette, Thimysta C. / Furfine, Eric S. et al. | 1998
- 2872
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Synthesis, Opioid Receptor Binding, and Bioassay of Naltrindole Analogues Substituted in the Indolic Benzene MoietyAnanthan, Subramaniam / Johnson, Cheryl A. / Carter, Ronald L. / Clayton, Sarah D. / Rice, Kenner C. / Xu, Heng / Davis, Peg / Porreca, Frank / Rothman, Richard B. et al. | 1998
- 2882
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β-Lactam Derivatives as Inhibitors of Human Cytomegalovirus ProteaseYoakim, Christiane / Ogilvie, William W. / Cameron, Dale R. / Chabot, Catherine / Guse, Ingrid / Haché, Bruno / Naud, Julie / O'Meara, Jeff A. / Plante, Raymond / Déziel, Robert et al. | 1998
- 2882
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b-Lactam Derivatives as Inhibitors of Human Cytomegalovirus ProteaseYoakim, Christiane et al. | 1998
- 2892
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Nucleosides and Nucleotides. 175. Structural Requirements of the Sugar Moiety for the Antitumor Activities of New Nucleoside Antimetabolites, 1-(3-C-Ethynyl-β-d-r ibo-pentofuranosyl)cytosine and -uracilHattori, Hideshi / Nozawa, Eisuke / Iino, Tomoharu / Yoshimura, Yuichi / Shuto, Satoshi / Shimamoto, Yuji / Nomura, Makoto / Fukushima, Masakazu / Tanaka, Motohiro / Sasaki, Takuma et al. | 1998
- 2892
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Nucleosides and Nucleotides. 175. Structural Requirements of the Sugar Moiety for the Antitumor Activities of New Nucleoside Antimetabolites, 1-(3-C-Ethynyl-b-D-ribo-pentofuranosyl) cytosine and -uracilHattori, Hideshi et al. | 1998
- 2903
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Prodrugs of Nitroxyl and Nitrosobenzene as Cascade Latentiated Inhibitors of Aldehyde DehydrogenaseConway, Terry T. / DeMaster, Eugene G. / Lee, Melinda J. C. / Nagasawa, Herbert T. et al. | 1998
- 2910
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Frontiers in Neurobiology 3. Amino Acid Neurotransmission Edited by F. Anne Stephenson and Anthony J. Turner. Portland Press, London. 1998. xiv + 247 pp. 16 × 23.5 cm. ISBN 1-85578-0801. $127.50.Enna, S. J. et al. | 1998
- 2910
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Frontiers in Neurobiology 3. Amino Acid NeurotransmissionEnna, S.J. et al. | 1998
- 2910
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The P2 Nucleotide Receptors Edited by John T. Turner, Gary A. Weisman, and Jeffrey S. Fedan. Humana Press, Totowa, NJ. 1997. xi + 440 pp. 16 × 23.5 cm. ISBN 0-89603-425-9. $139.00.Bhagwat, Shripad S. et al. | 1998
- 2910
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The P2 Nucleotide ReceptorsBhagwat, Shripad S. et al. | 1998