Combined in Vitro–in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor (Unknown)
- New search for: Matsson, Elin M.
- New search for: Eriksson, Ulf G.
- New search for: Palm, Johan E.
- New search for: Artursson, Per
- New search for: Karlgren, Maria
- New search for: Lazorova, Lucia
- New search for: Brännström, Marie
- New search for: Ekdahl, Anja
- New search for: Dunér, Kristina
- New search for: Knutson, Lars
- New search for: Johansson, Susanne
- New search for: Schützer, Kajs-Marie
- New search for: Lennernäs, Hans
- New search for: Matsson, Elin M.
- New search for: Eriksson, Ulf G.
- New search for: Palm, Johan E.
- New search for: Artursson, Per
- New search for: Karlgren, Maria
- New search for: Lazorova, Lucia
- New search for: Brännström, Marie
- New search for: Ekdahl, Anja
- New search for: Dunér, Kristina
- New search for: Knutson, Lars
- New search for: Johansson, Susanne
- New search for: Schützer, Kajs-Marie
- New search for: Lennernäs, Hans
In:
Molecular
Pharmaceutics
;
10
, 11
;
4252-4262
;
2013
- Article (Journal) / Electronic Resource
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Title:Combined in Vitro–in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin Inhibitor
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Additional title:Mol. Pharmaceutics
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Contributors:Matsson, Elin M. ( author ) / Eriksson, Ulf G. ( author ) / Palm, Johan E. ( author ) / Artursson, Per ( author ) / Karlgren, Maria ( author ) / Lazorova, Lucia ( author ) / Brännström, Marie ( author ) / Ekdahl, Anja ( author ) / Dunér, Kristina ( author ) / Knutson, Lars ( author )
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Published in:Molecular Pharmaceutics ; 10, 11 ; 4252-4262
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Publisher:
- New search for: American Chemical Society
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Publication date:2013-11-04
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ISSN:
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Coden:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Keywords:
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Source:
Table of contents – Volume 10, Issue 11
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3967
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Physical Chemical Drug–Drug Interactions from Drug Discovery to Registration: New Opportunities for the Pharmaceutical Scientist To Impact Drug DevelopmentWare, Joseph A. / Dalziel, Gena et al. | 2013
- 3970
-
Impaired Drug Absorption Due to High Stomach pH: A Review of Strategies for Mitigation of Such Effect To Enable Pharmaceutical Product DevelopmentMitra, Amitava / Kesisoglou, Filippos et al. | 2013
- 3980
-
Systemic Concentrations Can Limit the Oral Absorption of Poorly Soluble Drugs: An Investigation of Non-Sink Permeation Using Physiologically Based Pharmacokinetic ModelingChiang, Po-Chang / La, Hank / Zhang, Haiming / Wong, Harvey et al. | 2013
- 3989
-
Ion Pairing with Bile Salts Modulates Intestinal Permeability and Contributes to Food–Drug Interaction of BCS Class III Compound Trospium ChlorideHeinen, Christian A. / Reuss, Stefan / Amidon, Gordon L. / Langguth, Peter et al. | 2013
- 3997
-
Investigation of the Rat Model for Preclinical Evaluation of pH-Dependent Oral Absorption in HumansLubach, Joseph W. / Chen, Jacob Z. / Hau, Jonathan / Imperio, Jose / Coraggio, Melis / Liu, Lichuan / Wong, Harvey et al. | 2013
- 4005
-
Fumaric Acid Microenvironment Tablet Formulation and Process Development for Crystalline Cenicriviroc Mesylate, a BCS IV CompoundMenning, Mark M. / Dalziel, Sean M. et al. | 2013
- 4016
-
Mechanistic Understanding of the Effect of PPIs and Acidic Carbonated Beverages on the Oral Absorption of Itraconazole Based on Absorption Modeling with Appropriate in Vitro DataFotaki, Nikoletta / Klein, Sandra et al. | 2013
- 4024
-
Pharmacokinetics and Absorption of the Anticancer Agents Dasatinib and GDC-0941 under Various Gastric Conditions in Dogs – Reversing the Effect of Elevated Gastric pH with Betaine HClPang, Jodie / Dalziel, Gena / Dean, Brian / Ware, Joseph A. / Salphati, Laurent et al. | 2013
- 4032
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Gastric Reacidification with Betaine HCl in Healthy Volunteers with Rabeprazole-Induced HypochlorhydriaYago, Marc R. / Frymoyer, Adam R. / Smelick, Gillian S. / Frassetto, Lynda A. / Budha, Nageshwar R. / Dresser, Mark J. / Ware, Joseph A. / Benet, Leslie Z. et al. | 2013
- 4038
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Effect of P‑Glycoprotein on the Rat Intestinal Permeability and Metabolism of the BDDCS Class 1 Drug VerapamilEstudante, Margarida / Maya, Manuela / Morais, José G. / Soveral, Graça / Benet, Leslie Z. et al. | 2013
- 4046
-
Absolute Bioavailability and Effect of Formulation Change, Food, or Elevated pH with Rabeprazole on Cobimetinib Absorption in Healthy SubjectsMusib, Luna / Choo, Edna / Deng, Yuzhong / Eppler, Steve / Rooney, Isabelle / Chan, Iris T. / Dresser, Mark J. et al. | 2013
- 4055
-
Prevalence of Acid-Reducing Agents (ARA) in Cancer Populations and ARA Drug–Drug Interaction Potential for Molecular Targeted Agents in Clinical DevelopmentSmelick, Gillian S. / Heffron, Timothy P. / Chu, Laura / Dean, Brian / West, David A. / DuVall, Scott L. / Lum, Bert L. / Budha, Nageshwar / Holden, Scott N. / Benet, Leslie Z. et al. | 2013
- 4063
-
Assessing the Risk of pH-Dependent Absorption for New Molecular Entities: A Novel in Vitro Dissolution Test, Physicochemical Analysis, and Risk Assessment StrategyMathias, Neil R. / Xu, Yan / Patel, Dhaval / Grass, Michael / Caldwell, Brett / Jager, Casey / Mullin, Jim / Hansen, Luke / Crison, John / Saari, Amy et al. | 2013
- 4074
-
Impact of Food and the Proton Pump Inhibitor Rabeprazole on the Pharmacokinetics of GDC-0941 in Healthy Volunteers: Bench to Bedside Investigation of pH-Dependent SolubilityWare, Joseph A. / Dalziel, Gena / Jin, Jin Y. / Pellett, Jackson D. / Smelick, Gillian S. / West, David A. / Salphati, Laurent / Ding, Xiao / Sutton, Rebecca / Fridyland, Jane et al. | 2013
- 4082
-
Overcoming Nonviral Gene Delivery Barriers: Perspective and FutureJones, Charles H. / Chen, Chih-Kuang / Ravikrishnan, Anitha / Rane, Snehal / Pfeifer, Blaine A. et al. | 2013
- 4099
-
In Vivo Safety Evaluation of Polyarginine Coated Magnetic NanovectorsVeiseh, Omid / Kievit, Forrest M. / Liu, Vicki / Fang, Chen / Stephen, Zachary R. / Ellenbogen, Richard G. / Zhang, Miqin et al. | 2013
- 4107
-
Poly(aminoether)–Gold Nanorod Assemblies for shRNA Plasmid-Induced Gene SilencingRamos, James / Rege, Kaushal et al. | 2013
- 4120
-
Spatiotemporal Cellular Imaging of Polymer–pDNA Nanocomplexes Affords in Situ Morphology and Trafficking TrendsIngle, Nilesh P. / Xue, Lian / Reineke, Theresa M. et al. | 2013
- 4136
-
A Molecular Dynamics Approach for Predicting the Glass Transition Temperature and Plasticization Effect in Amorphous PharmaceuticalsGupta, Jasmine / Nunes, Cletus / Jonnalagadda, Sriramakamal et al. | 2013
- 4146
-
Characterization of Polymer Adsorption onto Drug Nanoparticles Using Depletion Measurements and Small-Angle Neutron ScatteringGoodwin, Daniel J. / Sepassi, Shadi / King, Stephen M. / Holland, Simon J. / Martini, Luigi G. / Lawrence, M. Jayne et al. | 2013
- 4159
-
In Vitro and in Vivo Evaluation of Osteoporosis Therapeutic Peptide PTH 1–34 Loaded PEGylated Chitosan NanoparticlesNarayanan, Deepa / Anitha, A. / Jayakumar, R. / Chennazhi, K. P. et al. | 2013
- 4168
-
Thrombin-Targeted Liposomes Establish a Sustained Localized Anticlotting Barrier against Acute ThrombosisPalekar, Rohun U. / Myerson, Jacob W. / Schlesinger, Paul H. / Sadler, J. Evan / Pan, Hua / Wickline, Samuel A. et al. | 2013
- 4176
-
Probing the Effects of Hapten Stability on Cocaine Vaccine ImmunogenicityCai, Xiaoqing / Whitfield, Timothy / Moreno, Amira Y. / Grant, Yanabel / Hixon, Mark S. / Koob, George F. / Janda, Kim D. et al. | 2013
- 4185
-
Noninvasive Fluorescence Resonance Energy Transfer Imaging of in Vivo Premature Drug Release from Polymeric NanoparticlesZou, Peng / Chen, Hongwei / Paholak, Hayley J. / Sun, Duxin et al. | 2013
- 4195
-
Improved Lentiviral Transduction of ALS Motoneurons in Vivo via Dual TargetingO’Leary, Valerie B. / Ovsepian, Saak V. / Bodeker, MacDara / Dolly, J. Oliver et al. | 2013
- 4207
-
Quantitative Prediction of Renal Transporter-Mediated Clinical Drug–Drug InteractionsFeng, Bo / Hurst, Susan / Lu, Yasong / Varma, Manthena V. / Rotter, Charles J. / El-Kattan, Ayman / Lockwood, Peter / Corrigan, Brian et al. | 2013
- 4216
-
Confocal UV and Resonance Raman Microscopic Imaging of Pharmaceutical ProductsVogt, Frederick G. / Strohmeier, Mark et al. | 2013
- 4229
-
Active Targeting of Block Copolymer Micelles with Trastuzumab Fab Fragments and Nuclear Localization Signal Leads to Increased Tumor Uptake and Nuclear Localization in HER2-Overexpressing XenograftsHoang, Bryan / Ekdawi, Sandra N. / Reilly, Raymond M. / Allen, Christine et al. | 2013
- 4242
-
Potential Markers of Cisplatin Treatment Response Unveiled by NMR Metabolomics of Human Lung CellsDuarte, I. F. / Ladeirinha, A. F. / Lamego, I. / Gil, A. M. / Carvalho, L. / Carreira, I. M. / Melo, J. B. et al. | 2013
- 4252
-
Combined in Vitro–in Vivo Approach To Assess the Hepatobiliary Disposition of a Novel Oral Thrombin InhibitorMatsson, Elin M. / Eriksson, Ulf G. / Palm, Johan E. / Artursson, Per / Karlgren, Maria / Lazorova, Lucia / Brännström, Marie / Ekdahl, Anja / Dunér, Kristina / Knutson, Lars et al. | 2013
- 4263
-
In Vivo Imaging of Bone Using a Deep-Red Fluorescent Molecular Probe Bearing Multiple Iminodiacetate GroupsHarmatys, Kara M. / Cole, Erin L. / Smith, Bradley D. et al. | 2013
- 4272
-
Microneedle Integrated Transdermal Patch for Fast Onset and Sustained Delivery of LidocaineKochhar, Jaspreet Singh / Lim, Wan Xuan Selina / Zou, Shui / Foo, Wei Yan / Pan, Jing / Kang, Lifeng et al. | 2013
- 4281
-
Sirolimus Encapsulated Liposomes for Cancer Therapy: Physicochemical and Mechanical Characterization of Sirolimus Distribution within Liposome BilayersOnyesom, Ichioma / Lamprou, Dimitrios A. / Sygellou, Lamprini / Owusu-Ware, Samuel K. / Antonijevic, Milan / Chowdhry, Babur Z. / Douroumis, Dennis et al. | 2013
- 4294
-
Characterization of a Water–Solid Interaction in a Partially Ordered SystemChakravarty, Paroma / Lubach, Joseph W. et al. | 2013
- 4301
-
Polymyxin B Treatment Improves Bactofection Efficacy and Reduces CytotoxicityJones, Charles H. / Rane, Snehal / Patt, Emily / Ravikrishnan, Anitha / Chen, Chih-Kuang / Cheng, Chong / Pfeifer, Blaine A. et al. | 2013
- 4309
-
Evaluation of 111In-Labeled EPep and FibPep as Tracers for Fibrin SPECT ImagingStarmans, Lucas W. E. / van Duijnhoven, Sander M. J. / Rossin, Raffaella / Berben, Monique / Aime, Silvio / Daemen, Mat J. A. P. / Nicolay, Klaas / Grüll, Holger et al. | 2013
- 4322
-
Controlled Iontophoretic Transport of Huperzine A across Skin in Vitro and in Vivo: Effect of Delivery Conditions and Comparison of Pharmacokinetic ModelsKalaria, Dhaval R. / Patel, Pratikkumar / Merino, Virginia / Patravale, Vandana B. / Kalia, Yogeshvar N. et al. | 2013
- 4330
-
Evolution of Supersaturation of Amorphous Pharmaceuticals: The Effect of Rate of Supersaturation GenerationSun, Dajun D. / Lee, Ping I. et al. | 2013
- 4347
-
Modified Trastuzumab and Cetuximab Mediate Efficient Toxin Delivery While Retaining Antibody-Dependent Cell-Mediated Cytotoxicity in Target CellsGilabert-Oriol, Roger / Thakur, Mayank / von Mallinckrodt, Benedicta / Hug, Thomas / Wiesner, Burkhard / Eichhorst, Jenny / Melzig, Matthias F. / Fuchs, Hendrik / Weng, Alexander et al. | 2013
- 4358
-
A Novel SERCA Inhibitor Demonstrates Synergy with Classic SERCA Inhibitors and Targets Multidrug-Resistant AMLBleeker, Nicholas P. / Cornea, Razvan L. / Thomas, David D. / Xing, Chengguo et al. | 2013
- 4367
-
Flash Nanoprecipitation: Particle Structure and StabilityPustulka, Kevin M. / Wohl, Adam R. / Lee, Han Seung / Michel, Andrew R. / Han, Jing / Hoye, Thomas R. / McCormick, Alon V. / Panyam, Jayanth / Macosko, Christopher W. et al. | 2013
- 4378
-
Purely in Silico BCS Classification: Science Based Quality Standards for the World’s DrugsDahan, Arik / Wolk, Omri / Kim, Young Hoon / Ramachandran, Chandrasekharan / Crippen, Gordon M. / Takagi, Toshihide / Bermejo, Marival / Amidon, Gordon L. et al. | 2013
- 4391
-
How Does the Cell Overcome LCP Nanoparticle-Induced Calcium Toxicity?Tseng, Yu-Cheng / Yang, Angela / Huang, Leaf et al. | 2013