[(1H-Imidazol-1-yl)methyl]- and [(3-pyridinyl)methyl]pyrroles as thromboxane synthetase inhibitors (English)
National licence
- New search for: Martinez, Gregory R.
- New search for: Hirschfeld, Donald R.
- New search for: Maloney, Patrick J.
- New search for: Yang, Diana S.
- New search for: Rosenkranz, Roberto P.
- New search for: Walker, K. A. M.
- New search for: Martinez, Gregory R.
- New search for: Hirschfeld, Donald R.
- New search for: Maloney, Patrick J.
- New search for: Yang, Diana S.
- New search for: Rosenkranz, Roberto P.
- New search for: Walker, K. A. M.
In:
Journal of Medicinal Chemistry
;
32
, 4
;
890-897
;
1989
-
ISSN:
- Article (Journal) / Electronic Resource
-
Title:[(1H-Imidazol-1-yl)methyl]- and [(3-pyridinyl)methyl]pyrroles as thromboxane synthetase inhibitors
-
Additional title:J. Med. Chem.
-
Contributors:Martinez, Gregory R. ( author ) / Hirschfeld, Donald R. ( author ) / Maloney, Patrick J. ( author ) / Yang, Diana S. ( author ) / Rosenkranz, Roberto P. ( author ) / Walker, K. A. M. ( author )
-
Published in:Journal of Medicinal Chemistry ; 32, 4 ; 890-897
-
Publisher:
- New search for: American Chemical Society
-
Publication date:1989-04-01
-
ISSN:
-
Coden:
-
DOI:
-
Type of media:Article (Journal)
-
Type of material:Electronic Resource
-
Language:English
-
Source:
Table of contents – Volume 32, Issue 4
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 735
-
Benzofurans as mechanism-based inhibitors of dopamine .beta.-hydroxylaseFarrington, G. King / Kumar, Alok / Villafranca, Joseph J. et al. | 1989
- 737
-
Carboxyalkyl dipeptides with atrial natriuretic factor potentiating and antihypertensive activityHaslanger, Martin F. / Sybertz, Edmund J. / Neustadt, Bernard R. / Smith, Elizabeth M. / Nechuta, Terry L. / Berger, Joel et al. | 1989
- 739
-
Hybrid cholecystokinin (CCK) antagonists: new implications in the design and modification of CCK antagonistsKerwin, James F. / Nadzan, Alex M. / Kopecka, Hana / Lin, Chun Wel / Miller, Thomas / Witte, David / Burt, Stanley et al. | 1989
- 742
-
Analogs of cisplatin derived from diaminodideoxytetritols. Synthesis and activity against the ADJ/PC6 plasmacytoma in miceHaines, Alan H. / Morley, Christopher / Murrer, Barry A. et al. | 1989
- 746
-
Analysis of the in vitro antiviral activity of certain ribonucleosides against parainfluenza virus using a novel computer aided receptor modeling procedureGhose, Arup K. / Crippen, Gordon M. / Revankar, Ganapathi R. / McKernan, Patricia A. / Smee, Donald F. / Robins, Roland K. et al. | 1989
- 757
-
Computer assisted design and synthesis of novel aldose reductase inhibitorsButera, John / Bagli, Jehan / Doubleday, Wendel / Humber, Leslie / Treasurywala, Adi / Loughney, Deborah / Sestanj, Kazimir / Millen, Jane / Sredy, Janet et al. | 1989
- 765
-
Topography and conformational preferences of 6,7,8,9-tetrahydro-1-hydroxy-N,N-dipropyl-5H-benzocyclohepten-6-ylamine. A rationale for the dopaminergic inactivityKarlen, Anders / Helander, Anne / Kenne, Lennart / Hacksell, Uli et al. | 1989
- 774
-
Synthesis, DNA-binding properties, and antitumor activity of novel distamycin derivativesArcamone, Federico Maria / Animati, Fabio / Barbieri, Brunella / Configliacchi, Emanuela / D'Alessio, Roberto / Geroni, Cristina / Giuliani, Fernando Carlo / Lazzari, Ettore / Menozzi, Milena et al. | 1989
- 779
-
Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions with 5-HT1A receptors in the brainBjoerk, Lena / Hoeoek, Berit Backlund / Nelson, David L. / Anden, Nils Erik / Hacksell, Uli et al. | 1989
- 783
-
Synthesis and biological evaluation of de(acetylglucosaminyl)didehydrodeoxy derivatives of teicoplanin antibioticsMalabarba, Adriano / Trani, Aldo / Tarzia, Giorgio / Ferrari, Pietro / Pallanza, Rosa / Berti, Marisa et al. | 1989
- 788
-
Synthesis of congeners and prodrugs. 3. Water-soluble prodrugs of taxol with potent antitumor activityDeutsch, H. M. / Glinski, J. A. / Hernandez, M. / Haugwitz, R. D. / Narayanan, V. L. / Suffness, M. / Zalkow, Leon H. et al. | 1989
- 793
-
Potential antitumor agents. 58. Synthesis and structure-activity relationships of substituted xanthenone-4-acetic acids active against the colon 38 tumor in vivoRewcastle, Gordon W. / Atwell, Graham J. / Baguley, Bruce C. / Calveley, Stephen B. / Denny, William A. et al. | 1989
- 799
-
2'-Fluorinated isonucleosides. 1. Synthesis and biological activity of some methyl 2'-deoxy-2'-fluoro-2'-pyrimidinyl-D-arabinopyranosidesBobek, M. / An, S. H. / Skrincosky, D. / De Clercq, E. / Bernacki, R. J. et al. | 1989
- 807
-
Hydroxyacetophenone-derived antagonists of the peptidoleukotrienesBrown, Frederick J. / Bernstein, Peter R. / Cronk, Laura A. / Dosset, David L. / Hebbel, Kevin C. / Maduskuie, Thomas P. / Shapiro, Howard S. / Vacek, Edward P. / Yee, Ying K. et al. | 1989
- 827
-
Synthesis and pharmacology of a series of 3- and 4-(phosphonoalkyl)pyridine- and -piperidine-2-carboxylic acids. Potent N-methyl-D-aspartate receptor antagonistsOrnstein, Paul L. / Schaus, John M. / Chambers, John W. / Huser, Diane L. / Leander, J. David / Wong, David T. / Paschal, Jonathan W. / Jones, Noel D. / Deeter, Jack B. et al. | 1989
- 834
-
Retinobenzoic acids. 2. Structure-activity relationships of chalcone-4-carboxylic acids and flavone-4'-carboxylic acidsKagechika, Hiroyuki / Kawachi, Emiko / Hashimoto, Yuichi / Shudo, Koichi et al. | 1989
- 841
-
Synthesis of some novel potent and selective catechol O-methyltransferase inhibitorsBackstrom, Reijo / Honkanen, Erkki / Pippuri, Aino / Kairisalo, Pekka / Pystynen, Jarmo / Heinola, Kalevi / Nissinen, Erkki / Linden, Inge Britt / Mannisto, Pekka T. et al. | 1989
- 847
-
Quinazoline antifolates inhibiting thymidylate synthase: 2-desamino derivatives with enhanced solubility and potencyJones, Terence R. / Thornton, Timothy J. / Flinn, Anthony / Jackman, Ann L. / Newell, D. R. / Calvert, A. Hilary et al. | 1989
- 852
-
Comparison of the biological effects of selected 5,8-dideazafolate analogs with their 2-desamino counterpartsHynes, John B. / Patil, Shirish A. / Hagan, Robert L. / Cole, Aimee / Kohler, William / Freisheim, James H. et al. | 1989
- 856
-
Synthesis and evaluation of the pharmacological activity of rigid analogs of sympathomimetic catecholamines derived from bicyclo[2.2.1]heptaneBalsamo, A. / Breschi, M. C. / Lapucci, A. / Macchia, B. / Macchia, F. / Martinotti, E. / Nencetti, S. / Nieri, P. / Orlandini, E. et al. | 1989
- 859
-
Design and synthesis of propranolol analogs as serotonergic agentsPierson, M. Edward / Lyon, Robert A. / Titeler, Milt / Kowalski, Paul / Glennon, Richard A. et al. | 1989
- 863
-
Conformationally restricted analogs of the muscarinic agent N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamideLundkvist, J. R. Michael / Ringdahl, Bjorn / Hacksell, Uli et al. | 1989
- 869
-
Identification of structural requirements for analogs of atrial natriuretic peptide (ANP) to discriminate between ANP receptor subtypesBovy, Philippe R. / O'Neal, Joan M. / Olins, Gillian M. / Patton, Dennis R. et al. | 1989
- 874
-
Synthesis and D2 dopaminergic activity of pyrrolidinium, tetrahydrothiophenium, and tetrahydrothiophene analogs of sulpirideHarrold, Marc W. / Wallace, Raye Ann / Farooqui, Tahira / Wallace, Lane J. / Uretsky, Norman / Miller, Duane D. et al. | 1989
- 880
-
A minor modification of residue 1 in potent vasopressin antagonists dramatically reduces agonist activityHuffman, William F. / Albrightson-Winslow, Christine / Brickson, Bridget / Bryan, Heidemarie G. / Caldwell, Nancy / Dytko, George / Eggleston, Drake S. / Kinter, Lewis B. / Moore, Michael L. et al. | 1989
- 885
-
Approaches to isozyme-specific inhibitors. 16. A novel methyl-C5' covalent adduct of L-ethionine and .beta.,.gamma.-imido-ATP as a potent multisubstrate inhibitor of rat methionine adenosyltransferasesVrudhula, Vivekananda M. / Kappler, Francis / Afshar, Carol / Ginell, Stephan L. / Lessinger, Leslie / Hampton, Alexander et al. | 1989
- 890
-
[(1H-Imidazol-1-yl)methyl]- and [(3-pyridinyl)methyl]pyrroles as thromboxane synthetase inhibitorsMartinez, Gregory R. / Hirschfeld, Donald R. / Maloney, Patrick J. / Yang, Diana S. / Rosenkranz, Roberto P. / Walker, K. A. M. et al. | 1989
- 898
-
Topographic probes of angiotensin and receptor: potent angiotensin II agonist containing diphenylalanine and long-acting antagonists containing biphenylalanine and 2-indan amino acid in position 8Hsieh, Kun Hwa / LaHann, Thomas R. / Speth, Robert C. et al. | 1989
- 904
-
New sensitizers for photodynamic therapy. Controlled synthesis of purpurins and their effect on normal tissueMorgan, Alan R. / Rampersaud, Ashraff / Garbo, Greta M. / Keck, Rick W. / Selman, Steven H. et al. | 1989
- 909
-
Book Reviews| 1989
-
Masthead| 1989