SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agents (English)
- New search for: Gigante, Federica
- New search for: Kaiser, Marcel
- New search for: Brun, Reto
- New search for: Gilbert, Ian H.
- New search for: Gigante, Federica
- New search for: Kaiser, Marcel
- New search for: Brun, Reto
- New search for: Gilbert, Ian H.
In:
Bioorganic and Medicinal Chemistry
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17
, 16
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5950-5961
;
2009
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ISSN:
- Article (Journal) / Electronic Resource
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Title:SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agents
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Contributors:Gigante, Federica ( author ) / Kaiser, Marcel ( author ) / Brun, Reto ( author ) / Gilbert, Ian H. ( author )
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Published in:Bioorganic and Medicinal Chemistry ; 17, 16 ; 5950-5961
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Publisher:
- New search for: Elsevier Ltd
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Publication date:2009-06-28
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Size:12 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 17, Issue 16
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 5733
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Graphical contents list| 2009
- 5744
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The search for potent, small molecule NNRTIs: A reviewPrajapati, Dhaval G. / Ramajayam, R. / Yadav, Mange Ram / Giridhar, Rajani et al. | 2009
- 5763
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Synthesis of orthogonally reactive FK506 derivatives via olefin cross metathesisMarinec, Paul S. / Evans, Christopher G. / Gibbons, Garrett S. / Tarnowski, Malloree A. / Overbeek, Daniel L. / Gestwicki, Jason E. et al. | 2009
- 5769
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Synthesis of [19, 35, 36-13C3]-labeled TAK779 as a molecular probeKonno, Hiroyuki / Aimoto, Saburo / Smith, Steven O. / Nosaka, Kazuto / Akaji, Kenichi et al. | 2009
- 5775
-
Synthesis and biological evaluation of imidazole thioacetanilides as novel non-nucleoside HIV-1 reverse transcriptase inhibitorsZhan, Peng / Liu, Xinyong / Zhu, Junjie / Fang, Zengjun / Li, Zhenyu / Pannecouque, Christophe / Clercq, Erik De et al. | 2009
- 5782
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Synthesis and characterizations of novel quinoline derivatives having mixed ligand activities at the κ and μ receptors: Potential therapeutic efficacy against morphine dependenceDeb, Ishani / Paira, Priyankar / Hazra, Abhijit / Banerjee, Sukdeb / Dutta, Pradip Kumar / Mondal, Nirup Bikash / Das, Sumantra et al. | 2009
- 5782
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Synthesis and characterizations of novel quinoline derivatives having mixed ligand activities at the k and m receptors: Potential therapeutic efficacy against morphine dependenceDeb, I. / Paira, P. / Hazra, A. / Banerjee, S. / Dutta, P. K. / Mondal, N. B. / Das, S. et al. | 2009
- 5791
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Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I–XIVAbdülkadir Coban, T. / Beydemir, Şükrü / Gücin, İlhami / Ekinci, Deniz / Innocenti, Alessio / Vullo, Daniela / Supuran, Claudiu T. et al. | 2009
- 5796
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A comprehensive study on the 5-hydroxytryptamine3A receptor binding of agonists serotonin and m-chlorophenylbiguanidineHazai, Eszter / Joshi, Prasad / Skoviak, Edward C. / Suryanarayanan, Asha / Schulte, Marvin K. / Bikadi, Zsolt et al. | 2009
- 5806
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A comprehensive study of Sansalvamide A derivatives: The structure–activity relationships of 78 derivatives in two pancreatic cancer cell linesPan, Po-Shen / Vasko, Robert C. / Lapera, Stephanie A. / Johnson, Victoria A. / Sellers, Robert P. / Lin, Chun-Chieh / Pan, Chung-Mao / Davis, Melinda R. / Ardi, Veronica C. / McAlpine, Shelli R. et al. | 2009
- 5826
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Immobilization of self-quenched DNA hairpin probe with a heterobifunctional reagent on a glass surface for sensitive detection of oligonucleotidesMisra, Arvind / Shahid, Mohammad et al. | 2009
- 5834
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Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapySeneci, Pierfausto / Bianchi, Aldo / Battaglia, Cristina / Belvisi, Laura / Bolognesi, Martino / Caprini, Andrea / Cossu, Federica / Franco, Elena de / Matteo, Marilenia de / Delia, Domenico et al. | 2009
- 5857
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Free and bound state structures of 6-O-methyl homoerythromycins and epitope mapping of their interactions with ribosomesNovak, Predrag / Barber, Jill / Čikoš, Ana / Arsic, Biljana / Plavec, Janez / Lazarevski, Gorjana / Tepeš, Predrag / Košutić-Hulita, Nada et al. | 2009
- 5868
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Evaluation of hydrogen bonds of ecdysteroids in the ligand–receptor interactions using a protein modeling systemHarada, Toshiyuki / Nakagawa, Yoshiaki / Akamatsu, Miki / Miyagawa, Hisashi et al. | 2009
- 5874
-
Vancomycin analogs: Seeking improved binding of d-Ala-d-Ala and d-Ala-d-Lac peptides by side-chain and backbone modificationsLeung, Siegfried S.F. / Tirado-Rives, Julian / Jorgensen, William L. et al. | 2009
- 5887
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Synthesis and characterization of modified nucleotides in the 970 hairpin loop of Escherichia coli 16S ribosomal RNAAbeydeera, N. Dinuka / Chow, Christine S. et al. | 2009
- 5894
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Structural basis for α-conotoxin potency and selectivityTurner, Matt / Eidemiller, Seth / Martin, Bryan / Narver, Andrew / Marshall, Joshua / Zemp, Logan / Cornell, Kenneth A. / McIntosh, J.M. / McDougal, Owen M. et al. | 2009
- 5894
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Structural basis for a-conotoxin potency and selectivityTurner, M. / Eidemiller, S. / Martin, B. / Narver, A. / Marshall, J. / Zemp, L. / Cornell, K. A. / Michael McIntosh, J. / McDougal, O. M. et al. | 2009
- 5900
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Design, synthesis, enzyme inhibition, and tumor cell growth inhibition of 2-anilinobenzamide derivatives as SIRT1 inhibitorsSuzuki, Takayoshi / Imai, Keiko / Imai, Erika / Iida, Shinsuke / Ueda, Ryuzo / Tsumoto, Hiroki / Nakagawa, Hidehiko / Miyata, Naoki et al. | 2009
- 5906
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ADMET rules of thumb II: A comparison of the effects of common substituents on a range of ADMET parametersGleeson, Paul / Bravi, Gianpaolo / Modi, Sandeep / Lowe, Daniel et al. | 2009
- 5920
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Novel 1,2,3-thiadiazole derivatives as HIV-1 NNRTIs with improved potency: Synthesis and preliminary SAR studiesZhan, Peng / Liu, Xinyong / Li, Zhenyu / Fang, Zengjun / Li, Zhong / Wang, Defeng / Pannecouque, Christophe / Clercq, Erik De et al. | 2009
- 5928
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Synthesis and properties of nucleoside derivatives acylated by chemically stable 2-(trimethylsilyl)benzoyl groupYamada, Ken / Taguchi, Haruhiko / Ohkubo, Akihiro / Seio, Kohji / Sekine, Mitsuo et al. | 2009
- 5933
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a-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteasesOrrling, K. M. / Marzahn, M. R. / Gutierrez-de-Teran, H. / Aqvist, J. / Dunn, B. M. / Larhed, M. et al. | 2009
- 5933
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α-Substituted norstatines as the transition-state mimic in inhibitors of multiple digestive vacuole malaria aspartic proteasesOrrling, Kristina M. / Marzahn, Melissa R. / Gutiérrez-de-Terán, Hugo / Åqvist, Johan / Dunn, Ben M. / Larhed, Mats et al. | 2009
- 5950
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SAR studies on azasterols as potential anti-trypanosomal and anti-leishmanial agentsGigante, Federica / Kaiser, Marcel / Brun, Reto / Gilbert, Ian H. et al. | 2009
- 5962
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Design, synthesis, and structure–activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agentsMonforte, Anna-Maria / Logoteta, Patrizia / Ferro, Stefania / Luca, Laura De / Iraci, Nunzio / Maga, Giovanni / Clercq, Erik De / Pannecouque, Christophe / Chimirri, Alba et al. | 2009
- 5968
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2-O-β-d-Glucopyranosyl-sn-glycerol based analogues of sulfoquinovosyldiacylglycerols (SQDG) and their role in inhibiting Epstein-Barr virus early antigen activationDangate, Milind / Franchini, Laura / Ronchetti, Fiamma / Arai, Takanari / Iida, Akira / Tokuda, Harukuni / Colombo, Diego et al. | 2009
- 5968
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2-O-b-d-Glucopyranosyl-sn-glycerol based analogues of sulfoquinovosyldiacylglycerols (SQDG) and their role in inhibiting Epstein-Barr virus early antigen activationDangate, M. / Franchini, L. / Ronchetti, F. / Arai, T. / Iida, A. / Tokuda, H. / Colombo, D. et al. | 2009
- 5974
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Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitorsAbadi, Ashraf H. / Ibrahim, Tamer M. / Abouzid, Khaled M. / Lehmann, Jochen / Tinsley, Heather N. / Gary, Bernard D. / Piazza, Gary A. et al. | 2009
- 5983
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Aerobic oxidation of indolomorphinan without the 4,5-epoxy bridge and subsequent rearrangement of the oxidation product to spiroindolinonyl-C-normorphinan derivativeFujii, Hideaki / Ogawa, Ryo / Ohata, Kenji / Nemoto, Toru / Nakajima, Mayumi / Hasebe, Ko / Mochizuki, Hidenori / Nagase, Hiroshi et al. | 2009
- 5989
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Synthesis, biological evaluation, and metabolic stability of acrylamide derivatives as novel CCR3 antagonistsSato, Ippei / Morihira, Koichiro / Inami, Hiroshi / Kubota, Hirokazu / Morokata, Tatsuaki / Suzuki, Keiko / Ohno, Kazuki / Iura, Yosuke / Nitta, Aiko / Imaoka, Takayuki et al. | 2009
- 6003
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Chromane derivatives of small aromatic molecules: Chemoenzymatic synthesis and growth inhibitory activity on human tumor cell line LoVo WTMacone, Alberto / Lendaro, Eugenio / Comandini, Alessandra / Rovardi, Irene / Matarese, Rosa Marina / Carraturo, Antonio / Bonamore, Alessandra et al. | 2009
- 6008
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Reactions of hydroxyl radical with bergenin, a natural poly phenol studied by pulse radiolysisSingh, Umang / Barik, Atanu / Priyadarsini, K. Indira et al. | 2009
- 6015
-
A highly sensitive probe detecting low pH area of HeLa cells based on rhodamine B modified b-cyclodextrinsHasegawa, T. / Kondo, Y. / Koizumi, Y. / Sugiyama, T. / Takeda, A. / Ito, S. / Hamada, F. et al. | 2009
- 6015
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A highly sensitive probe detecting low pH area of HeLa cells based on rhodamine B modified β-cyclodextrinsHasegawa, Takuto / Kondo, Yoshihiko / Koizumi, Yukio / Sugiyama, Toshihiro / Takeda, Akane / Ito, Shinichi / Hamada, Fumio et al. | 2009
- 6020
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Novel indoline-based acyl-CoA: cholesterol acyltransferase inhibitor: Effects of introducing a methanesulfonamide group on physicochemical properties and biological activitiesShoji, Yoshimichi / Takahashi, Kenji / Ohta, Masaru / Kasai, Masayasu / Kunishiro, Kazuyoshi / Kanda, Mamoru / Yogai, Satoko / Takeuchi, Yasuo / Shirahase, Hiroaki et al. | 2009
- 6032
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The marine natural-derived inhibitors of glycogen synthase kinase-3b phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modelingKhanfar, M. A. / Asal, B. A. / Mudit, M. / Kaddoumi, A. / El Sayed, K. A. et al. | 2009
- 6032
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The marine natural-derived inhibitors of glycogen synthase kinase-3β phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modelingKhanfar, Mohammad A. / Asal, Bilal Abu / Mudit, Mudit / Kaddoumi, Amal / El Sayed, Khalid A. et al. | 2009
- 6040
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Design, synthesis, and discovery of novel non-peptide inhibitor of Caspase-3 using ligand based and structure based virtual screening approachJhansi Lakshmi, P. / Suneel Kumar, B.V.S. / Nayana, Ravi Shasi / Srinivas Mohan, M. / Bolligarla, Ramababu / Das, Samar K. / Uday Bhanu, M. / Kondapi, Anand K. / Ravikumar, Muttineni et al. | 2009
- 6048
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Melanogenesis inhibitors from the rhizomes of Alpinia officinarum in B16 melanoma cellsMatsuda, Hisashi / Nakashima, Souichi / Oda, Yoshimi / Nakamura, Seikou / Yoshikawa, Masayuki et al. | 2009
- 6054
-
Characterization and DNA-interaction studies of 1,1-dicyano-2,2-ethylene dithiolate Ni(II) mixed-ligand complexes with 2-amino-5-methyl thiazole, 2-amino-2-thiazoline and imidazole. Crystal structure of [Ni(i-MNT)(2a-5mt)2]Cox, Philip J. / Psomas, George / Bolos, Christos A. et al. | 2009
- 6063
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Development of antitubercular compounds based on a 4-quinolylhydrazone scaffold. Further structure–activity relationship studiesGemma, Sandra / Savini, Luisa / Altarelli, Maria / Tripaldi, Pierangela / Chiasserini, Luisa / Coccone, Salvatore Sanna / Kumar, Vinod / Camodeca, Caterina / Campiani, Giuseppe / Novellino, Ettore et al. | 2009
- 6073
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Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1Aubry, Carine / Wilson, A. James / Emmerson, Daniel / Murphy, Emma / Chan, Yu Yam / Dickens, Michael P. / García, Marcos D. / Jenkins, Paul R. / Mahale, Sachin / Chaudhuri, Bhabatosh et al. | 2009
- 6085
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Synthesis, DNA intercalation and 3D QSAR analysis of cis-2,4,5-trisubstituted-1,3-dithiolanes as a novel class of antitumor agentsHuang, Fei / Zhao, Ming / Zhang, Xiaoyi / Wang, Chao / Qian, Keduo / Kuo, Reen-Yen / Morris-Natschke, Susan / Lee, Kuo-Hsiung / Peng, Shiqi et al. | 2009
- 6096
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Novel mannosyl derivatives of peptidoglycan monomer: Synthesis and biological evaluation of immunomodulatory propertiesRibić, Rosana / Habjanec, Lidija / Brgles, Marija / Tomić, Srđanka / Tomašić, Jelka et al. | 2009
- 6106
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Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptorAndo, Makoto / Sato, Nagaaki / Nagase, Tsuyoshi / Nagai, Keita / Ishikawa, Shiho / Takahashi, Hirobumi / Ohtake, Norikazu / Ito, Junko / Hirayama, Mioko / Mitobe, Yuko et al. | 2009
- 6123
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Synthesis and biological evaluation of sphingosine kinase substrates as sphingosine-1-phosphate receptor prodrugsFoss, Frank W. Jr. / Mathews, Thomas P. / Kharel, Yugesh / Kennedy, Perry C. / Snyder, Ashley H. / Davis, Michael D. / Lynch, Kevin R. / Macdonald, Timothy L. et al. | 2009
- 6137
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Anti-HBV and cytotoxic activities of pyranocoumarin derivativesSu, Chung-Ren / Yeh, Sheau Farn / Liu, Chih Miem / Damu, Amooru G. / Kuo, Tsung-Hsiao / Chiang, Po-Cheng / Bastow, Kenneth F. / Lee, Kuo-Hsiung / Wu, Tian-Shung et al. | 2008
- 6144
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Bioorganic & Medicinal Chemistry Reviews and Perspectives| 2009
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Instructions to contributors| 2009
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Editorial board| 2009