Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives (English)
- New search for: Babanezhad Harikandei, Kosar
- New search for: Salehi, Peyman
- New search for: Ebrahimi, Samad Nejad
- New search for: Bararjanian, Morteza
- New search for: Kaiser, Marcel
- New search for: Al-Harrasi, Ahmed
- New search for: Babanezhad Harikandei, Kosar
- New search for: Salehi, Peyman
- New search for: Ebrahimi, Samad Nejad
- New search for: Bararjanian, Morteza
- New search for: Kaiser, Marcel
- New search for: Al-Harrasi, Ahmed
In:
Bioorganic and Medicinal Chemistry
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28
, 1
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2019
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivatives
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Contributors:Babanezhad Harikandei, Kosar ( author ) / Salehi, Peyman ( author ) / Ebrahimi, Samad Nejad ( author ) / Bararjanian, Morteza ( author ) / Kaiser, Marcel ( author ) / Al-Harrasi, Ahmed ( author )
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Published in:
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Publisher:
- New search for: Elsevier Ltd
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Publication date:2019-10-25
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 28, Issue 1
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
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Investigating the effect of radiosensitizer for Ursolic Acid and Kamolonol Acetate on HCT-116 cell lineHasan Abdali, Maede / Afshar, Saeid / Sedighi Pashaki, Abdolazim / Dastan, Dara / Gholami, Mohammad Hadi / Mahmoudi, Roghayeh / Saidijam, Massoud et al. | 2019
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Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activitiesKamauchi, Hitoshi / Oda, Takumi / Horiuchi, Kanayo / Takao, Koichi / Sugita, Yoshiaki et al. | 2019
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Application of protein knockdown strategy targeting β-sheet structure to multiple disease-associated polyglutamine proteinsYamashita, Hiroko / Tomoshige, Shusuke / Nomura, Sayaka / Ohgane, Kenji / Hashimoto, Yuichi / Ishikawa, Minoru et al. | 2019
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Design, synthesis and biological evaluation of 8-(2-amino-1-hydroxyethyl)-6-hydroxy-1,4-benzoxazine-3(4H)-one derivatives as potent β2-adrenoceptor agonistsYi, Ce / Xing, Gang / Wang, Siqi / Li, Xiaoran / Liu, Yichuang / Li, Jinyan / Lin, Bin / Woo, Anthony Yiu-Ho / Zhang, Yuyang / Pan, Li et al. | 2019
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Editorial Board| 2019
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Kolavenic acid analog restores growth in HSET-overproducing fission yeast cells and multipolar mitosis in MDA-MB-231 human cellsKurisawa, Naoaki / Yukawa, Masashi / Koshino, Hiroyuki / Onodera, Takumu / Toda, Takashi / Kimura, Ken-ichi et al. | 2019
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Pan-specific and partially selective dye-labeled peptidic inhibitors of the polycomb paralog proteinsMilosevich, Natalia / McFarlane, James / Gignac, Michael C. / Li, Janessa / Brown, Tyler M. / Wilson, Chelsea R. / Devorkin, Lindsey / Croft, Caitlin S. / Hof, Rebecca / Paci, Irina et al. | 2019
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Identification of small molecule inhibitors of human COQ7Tsuganezawa, Keiko / Sekimata, Katsuhiko / Nakagawa, Yukari / Utata, Rei / Nakamura, Kana / Ogawa, Naoko / Koyama, Hiroo / Shirouzu, Mikako / Fukami, Takehiro / Kita, Kiyoshi et al. | 2019
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Discovery of metyltetraprole: Identification of tetrazolinone pharmacophore to overcome QoI resistanceMatsuzaki, Yuichi / Yoshimoto, Yuya / Arimori, Sadayuki / Kiguchi, So / Harada, Toshiyuki / Iwahashi, Fukumatsu et al. | 2019
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Lipidated α/Sulfono-α-AA heterogeneous peptides as antimicrobial agents for MRSASingh, Sylvia / Wang, Minghui / Gao, Ruixuan / Teng, Peng / Odom, Timothy / Zhang, En / Xu, Hai / Cai, Jianfeng et al. | 2019
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Artemisia: a promising plant for the treatment of cancerTaleghani, Akram / Emami, Seyed Ahmad / Tayarani-Najaran, Zahra et al. | 2019
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Preparation and biological evaluation of BACE1 inhibitors: Leveraging trans-cyclopropyl moieties as ligand efficient conformational constraintsWinneroski, Leonard L. / Erickson, Jon A. / Green, Steven J. / Lopez, Jose E. / Stout, Stephanie L. / Porter, Warren J. / Timm, David E. / Audia, James E. / Barberis, Mario / Beck, James P. et al. | 2019
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Modelling the binding mode of macrocycles: Docking and conformational samplingMartin, Sarah J. / Chen, I-Jen / Chan, A.W. Edith / Foloppe, Nicolas et al. | 2019
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Synthesis and antileishmanial activity of fluorinated rhodacyanine analogues: The ‘fluorine-walk’ analysisLasing, Thitiya / Phumee, Atchara / Siriyasatien, Padet / Chitchak, Kantima / Vanalabhpatana, Parichatr / Mak, Kit-Kay / Hee Ng, Chew / Vilaivan, Tirayut / Khotavivattana, Tanatorn et al. | 2019
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Discovery and preclinical development of AR453588 as an anti-diabetic glucokinase activatorHinklin, Ronald J. / Baer, Brian R. / Boyd, Steven A. / Chicarelli, Mark D. / Condroski, Kevin R. / DeWolf, Walter E. Jr. / Fischer, John / Frank, Michele / Hingorani, Gary P. / Lee, Patrice A. et al. | 2019
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Generation of highly potent DYRK1A-dependent inducers of human β-Cell replication via Multi-Dimensional compound optimizationAllegretti, Paul A. / Horton, Timothy M. / Abdolazimi, Yassan / Moeller, Hannah P. / Yeh, Benjamin / Caffet, Matthew / Michel, Guillermina / Smith, Mark / Annes, Justin P. et al. | 2019
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Discovery of N-ethylpyridine-2-carboxamide derivatives as a novel scaffold for orally active γ-secretase modulatorsSekioka, Ryuichi / Honda, Shugo / Honjo, Eriko / Suzuki, Takayuki / Akashiba, Hiroki / Mitani, Yasuyuki / Yamasaki, Shingo et al. | 2019
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Graphical Abstract Contents Continued| 2019
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Novel alkoxyamide-based histone deacetylase inhibitors reverse cisplatin resistance in chemoresistant cancer cellsAsfaha, Yodita / Schrenk, Christian / Alves Avelar, Leandro A. / Lange, Friedrich / Wang, Chenyin / Bandolik, Jan J. / Hamacher, Alexandra / Kassack, Matthias U. / Kurz, Thomas et al. | 2019
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Pyrazolopyrimide library screening in glioma cells discovers highly potent antiproliferative leads that target the PI3K/mTOR pathwayValero, Teresa / Baillache, Daniel J. / Fraser, Craig / Myers, Samuel H. / Unciti-Broceta, Asier et al. | 2019
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Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacologySutherland, Hamish S. / Tong, Amy S.T. / Choi, Peter J. / Blaser, Adrian / Franzblau, Scott G. / Cooper, Christopher B. / Upton, Anna M. / Lotlikar, Manisha / Denny, William A. / Palmer, Brian D. et al. | 2019
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Identification of antimalarial leads with dual falcipain-2 and falcipain-3 inhibitory activityRana, Devika / Kalamuddin, Md. / Sundriyal, Sandeep / Jaiswal, Varun / Sharma, Gaurav / Das Sarma, Koushik / Sijwali, Puran Singh / Mohmmed, Asif / Malhotra, Pawan / Mahindroo, Neeraj et al. | 2019
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Synthesis and biological activities of amino acids functionalized α-GalCer analoguesMa, Weiwei / Bi, Jingjing / Zhao, Chuanfang / Zhang, Zhiguo / Liu, Tongxin / Zhang, Guisheng et al. | 2019
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Structure-activity relationship study of the pyridine moiety of isothiazolo[4,3-b]pyridines as antiviral agents targeting cyclin G-associated kinaseMartinez-Gualda, Belén / Pu, Szu-Yuan / Froeyen, Mathy / Herdewijn, Piet / Einav, Shirit / De Jonghe, Steven et al. | 2019
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Identification of small-molecule urea derivatives as novel NAMPT inhibitors via pharmacophore-based virtual screeningOzgencil, Fikriye / Eren, Gokcen / Ozkan, Yesim / Guntekin-Ergun, Sezen / Cetin-Atalay, Rengul et al. | 2019
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The architecture of hydrogen and sulfur σ-hole interactions explain differences in the inhibitory potency of C-β-d-glucopyranosyl thiazoles, imidazoles and an N-β-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based designKyriakis, Efthimios / Karra, Aikaterini G. / Papaioannou, Olga / Solovou, Theodora / Skamnaki, Vassiliki T. / Liggri, Panagiota G.V. / Zographos, Spyros E. / Szennyes, Eszter / Bokor, Éva / Kun, Sándor et al. | 2019
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Mass spectrometry-based Cellular Thermal Shift Assay (CETSA®) for target deconvolution in phenotypic drug discoveryFriman, Tomas et al. | 2019
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Diversity & tractability revisited in collaborative small molecule phenotypic screening library designLahue, Brian R. / Glick, Meir / Tudor, Matthew / Johnson, Scott Arne / Diratsouian, Janet / Wildey, Mary Jo / Burton, Marybeth / Mazzola, Robert / Wassermann, Anne Mai et al. | 2019
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Synthesis and characterization of 64Cu- and Cy5.5-labeled tetraiodothyroacetic acid derivatives for tumor angiogenesis imagingKim, Hyunjung / Koo, Hyun-Jung / Ahn, Jinhee / Kim, Jung Young / Choi, Joon Young / Lee, Kyung-Han / Kim, Byung-Tae / Choe, Yearn Seong et al. | 2019
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Development and characterization of a 68Ga-labeled A20FMDV2 peptide probe for the PET imaging of αvβ6 integrin-positive pancreatic ductal adenocarcinomaUi, Takashi / Ueda, Masashi / Higaki, Yusuke / Kamino, Shinichiro / Sano, Kohei / Kimura, Hiroyuki / Saji, Hideo / Enomoto, Shuichi et al. | 2019
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Synthesis, in-vitro antiprotozoal activity and molecular docking study of isothiocyanate derivativesBabanezhad Harikandei, Kosar / Salehi, Peyman / Ebrahimi, Samad Nejad / Bararjanian, Morteza / Kaiser, Marcel / Al-Harrasi, Ahmed et al. | 2019
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Superior inhibition of influenza virus hemagglutinin-mediated fusion by indole-substituted spirothiazolidinonesCihan-Üstündağ, Gökçe / Zopun, Muhammet / Vanderlinden, Evelien / Ozkirimli, Elif / Persoons, Leentje / Çapan, Gültaze / Naesens, Lieve et al. | 2019
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Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cellsGnanasekaran, Krishna Kumar / Pouland, Tim / Bunce, Richard A. / Darrell Berlin, K. / Abuskhuna, Suaad / Bhandari, Dipendra / Mashayekhi, Maryam / Zhou, Donghua H. / Benbrook, Doris M. et al. | 2019
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Synthesis and evaluation of 2′-dihalo ribonucleotide prodrugs with activity against hepatitis C virusChris Krueger, A. / Chen, Hui-Ju / Randolph, John T. / Brown, Brian S. / Halvorsen, Geoff T. / Heyman, Howard R. / Li, Tongmei / Marvin, Christopher C. / Shanley, Jason P. / Voight, Eric A. et al. | 2019
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Design, synthesis and biological evaluation of substituted flavones and aurones as potential anti-influenza agentsChintakrindi, Anand S. / Gohil, Devanshi J. / Chowdhary, Abhay S. / Kanyalkar, Meena A. et al. | 2019
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Synthesis, in vitro and in vivo biological evaluation of novel graveolinine derivatives as potential anti-Alzheimer agentsLuo, Wen / Lv, Jian-Wu / Wang, Ting / Zhang, Zhi-Yang / Guo, Hui-Yan / Song, Zhi-Yi / Wang, Chao-Jie / Ma, Jing / Chen, Yi-ping et al. | 2019
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Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screeningMamontova, E.M. / Zakharenko, A.L. / Zakharova, O.D. / Dyrkheeva, N.S. / Volcho, K.P. / Reynisson, J. / Arabshahi, H.J. / Salakhutdinov, N.F. / Lavrik, O.I. et al. | 2019
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Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomideZhang, Fangqing / Wu, Zhenwei / Chen, Pan / Zhang, Jian / Wang, Tao / Zhou, Jinpei / Zhang, Huibin et al. | 2019
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Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modificationPeng, Kewen / Li, Yu / Bai, Ying / Jiang, Teng / Sun, Huiyong / Zhu, Qihua / Xu, Yungen et al. | 2019
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Discovery of novel small molecule induced selective degradation of the bromodomain and extra-terminal (BET) bromodomain protein BRD4 and BRD2 with cellular potenciesJiang, Fei / Wei, Qingyun / Li, Huili / Li, Hongmei / Cui, Yong / Ma, Yu / Chen, Haifang / Cao, Peng / Lu, Tao / Chen, Yadong et al. | 2019
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Graphical abstract TOC| 2019
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Design, synthesis and biological evaluation of imidazole and oxazole fragments as HIV-1 integrase-LEDGF/p75 disruptors and inhibitors of microbial pathogensRashamuse, Thompho J. / Harrison, Angela T. / Mosebi, Salerwe / van Vuuren, Sandy / Coyanis, E. Mabel / Bode, Moira L. et al. | 2019
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High content phenotypic screening identifies serotonin receptor modulators with selective activity upon breast cancer cell cycle and cytokine signaling pathwaysWarchal, Scott J. / Dawson, John C. / Shepherd, Emelie / Munro, Alison F. / Hughes, Rebecca E. / Makda, Ashraff / Carragher, Neil O. et al. | 2019
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Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structureDing, Zhongpeng / Ma, Mingxu / Zhong, Changjiang / Wang, Shixiao / Fu, Zhangyu / Hou, Yingwei / Liu, Yuqian / Zhong, Lili / Chu, Yanyan / Li, Feng et al. | 2019
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Bioothogonally applicable, π-extended rhodamines for super-resolution microscopy imaging for intracellular proteinsEgyed, Alexandra / Kormos, Attila / Söveges, Bianka / Németh, Krisztina / Kele, Péter et al. | 2019
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Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activityFuse, Shinichiro / Suzuki, Kensuke / Kuchimaru, Takahiro / Kadonosono, Tetsuya / Ueda, Hiroki / Sato, Shinichi / Kizaka-Kondoh, Shinae / Nakamura, Hiroyuki et al. | 2019
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Exploring structure-promiscuity relationships using dual-site promiscuity cliffs and corresponding single-site analogsHu, Huabin / Bajorath, Jürgen et al. | 2019
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Design of enkephalin modifications protected from brain extracellular peptidases providing long-term analgesiaKropotova, Ekaterina S. / Ivleva, Irina S. / Karpenko, Marina N. / Mosevitsky, Mark I. et al. | 2019
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Rational design, synthesis and biological profiling of new KDM4C inhibitorsLetfus, Vatroslav / Jelić, Dubravko / Bokulić, Ana / Petrinić Grba, Adriana / Koštrun, Sanja et al. | 2019
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Basil polysaccharides: A review on extraction, bioactivities and pharmacological applicationsZhan, Yanfei / An, Xinin / Wang, Shuang / Sun, Mengjia / Zhou, Honglei et al. | 2019
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Design and synthesis of cyanamides as potent and selective N-acylethanolamine acid amidase inhibitorsMalamas, Michael S. / Farah, Shrouq I. / Lamani, Manjunath / Pelekoudas, Dimitrios N. / Perry, Nicholas Thomas / Rajarshi, Girija / Miyabe, Christina Yume / Chandrashekhar, Honrao / West, Jay / Pavlopoulos, Spiro et al. | 2019
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Selenium bioisosteric replacement of adenosine derivatives promoting adiponectin secretion increases the binding affinity to peroxisome proliferator-activated receptor δAn, Seungchan / Yu, Jinha / Choi, Hongseok / Ko, Hyejin / Ahn, Sungjin / Shin, Jeayoung C. / Pyo, Jeong Joo / Jeong, Lak Shin / Noh, Minsoo et al. | 2019