Transgenic mice and Alzheimer's disease (English)
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In:
Neurobiology of Aging
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11
, 3
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326
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1990
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ISSN:
- Article (Journal) / Electronic Resource
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Title:Transgenic mice and Alzheimer's disease
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Contributors:Beer, J. ( author ) / Salbaum, J.M. ( author ) / Schlichtmann, E. ( author ) / Hoppe, P. ( author ) / Earley, S. ( author ) / Masters, C.L. ( author ) / Carlson, G.A. ( author ) / Beyreuther, K. ( author )
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Published in:Neurobiology of Aging ; 11, 3 ; 326
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Publisher:
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Publication date:1990-01-01
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Size:1 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Source:
Table of contents – Volume 11, Issue 3
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 169
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Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patientsMullaart, Erik / Boerrigter, Michael E.T.I. / Ravid, Rivka / Swaab, Dick F. / Vijg, Jan et al. | 1989
- 175
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Age-related decrease in sympathetic sprouting is primarily due to decreased target receptivity: implications for understanding brain agingCrutcher, K.A. et al. | 1989
- 185
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Effect of aging on NADPH-diaphorase neurons in laterodorsal tegmental nucleus and striatum of miceKawamata, Toshio / Nakamura, Shinichi / Akiguchi, Ichiro / Kimura, Jun / Kameyama, Masakuni / Kimura, Hiroshi / Takeda, Toshio et al. | 1989
- 193
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Age and fitness effects on EEG, ERPs, visual sensitivity, and cognitionDustman, R.E. / Emmerson, R.Y. / Ruhling, R.O. / Shearer, D.E. / Steinhaus, L.A. / Johnson, S.C. / Bonekat, H.W. / Shigeoka, J.W. et al. | 1989
- 201
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Neuronal population of area 4 during the life span of the rhesus monkeyTigges, Johannes / Herndon, James G. / Peters, Alan et al. | 1989
- 209
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Oral aluminum alters in vitro protein phosphorylation and kinase activities in rat brainJohnson, Gail V.W. / Cogdill, Keith W. / Jope, Richard S. et al. | 1989
- 217
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Loss of LH-RH neurons in the rostral forebrain of old female C57BL/6J miceMiller, M.M. / Joshi, D. / Billiar, R.B. / Nelson, J.F. et al. | 1989
- 223
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The elevation of immunoreactive beta-endorphin in old male rats is related to alterations in dopamine and serotoninForman, L.J. / Cavalieri, T. / Estilow, S. / Tatarian, G.T et al. | 1989
- 229
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Growth hormone and thyrotropin secretory profiles and provocative testing in aged ratsMillard, W.J. / Romano, T.M. / Simpkins, J.W. et al. | 1989
- 237
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The capacity to develop maternal behavior is enhanced during aging in ratsGonzalez, Daniel E. / Deis, Ricardo P. et al. | 1989
- 243
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Information related to research funding, grants and awards| 1990
- 244
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News and information related to the neurobiology of aging| 1990
- 246
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Calendar| 1990
- 251
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IntroductionColeman, Paul D. et al. | 1990
- 253
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Leuko-araiosis and prognosis in dementia| 1990
- 253
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The course of Alzheimer's disease as related to CSF biochemistry, neurological status and cognitive function| 1990
- 253
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Neuropsychological validation of two dementia categories — results of first prospective study| 1990
- 253
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The clinical course of Alzheimer's disease| 1990
- 254
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Clinical asessment of mental decline in elderly people| 1990
- 254
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Emotional disturbances in patients with Alzheimer's disease| 1990
- 254
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Heterogeneity of “Probable Alzheimer's disease”| 1990
- 254
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Rate of progression of Alzheimers disease a prospective study| 1990
- 255
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Language and memory processing in SDAT, depressive pseudodementia, and major depression/unipolar| 1990
- 255
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Evaluation of an expert system for dementia diagnostics (EVINCE): Expert system performs better than clinicians| 1990
- 255
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Dementia of frontal lobe type| 1990
- 255
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Accelerated progression of dementia of the Alzheimer type by development of seizures| 1990
- 256
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Psychopathology and frontal lobe involvement in primary degenerative and vascular dementia. 1. Clinical aspects| 1990
- 256
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A brief assessment battery for the diagnosis of probable Alzheimer's disease| 1990
- 256
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Neuropsychological evaluation of patients suspected of early Alzheimer's disease: Experimental studies with age associated memory impairment and dysthymia| 1990
- 256
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Clinical markers of early Alzheimers disease| 1990
- 256
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Increased serum insulin-like growth factor-I concentrations in institutionalized women with Alzheimer's disease| 1990
- 257
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Primary cerebellar degeneration presenting as progressive familial dementia| 1990
- 257
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Spatial disorientation in Alzheimer's disease (AD): Results of a one year follow-up| 1990
- 257
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Clinical relevance of myoclonus in Alzheimer's disease| 1990
- 258
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Cognitive decline and mortality in Alzheimer's disease (AD)| 1990
- 258
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Standing balance measures in Alzheimer's disease (AD)| 1990
- 258
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Appearance of neurofibriliary tangles in neocortex followed by five years of minimal cognitive decline| 1990
- 258
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Progressive aphasia due to lobar atrophy| 1990
- 258
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Vascular dementia — evidence of a subcortical small vessel subgroup| 1990
- 259
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Gait changes characteristic of individuals diagnosed as having senile dementia of the Alzheimer type| 1990
- 259
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Orienting of visual attention in Alzheimer's and Parkinson's disease| 1990
- 259
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Violence and psychosis in dementia of the Alzheimer's type| 1990
- 259
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Reaction time in normal aging and Alzheimer's disease| 1990
- 260
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Telephone screening for dementia in community dwelling elderly| 1990
- 260
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Regional deficits in cortical metabolism in petscanned Alzheimer cases correlate with postmortem biochemical indices of gliosis and not with choline acetyltransferase| 1990
- 260
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Brain energy metabolism and its significance for Alzheimer's disease| 1990
- 260
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Use of cued recall and selective reminding to detect dementia in a geriatric population| 1990
- 261
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The pathophysiology of Alzheimer's disease as identified with pet| 1990
- 261
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Quantitative MR in the evaluation of dementia| 1990
- 261
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Eeg brain mapping in diagnosis and treatment of SDAT and MID| 1990
- 261
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Positron emission tomography and Alzheimer's disease| 1990
- 262
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Diagnostic value of a combination of temporal lobe CT scans and SPET studies in dementia: Definition of a subgroup of patients with structural and metabolic changes| 1990
- 262
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Muscarinic and nicotinic contributions to the ad cortical perfusion abnormality| 1990
- 262
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Pet imaging of 11c-nicotine binding in the human brain — implications for drug dependence and dementia disorders| 1990
- 262
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Computerized EEG frequency analysis and topographic brain mapping in Alzheimer's disease and multi-infarct dementia| 1990
- 263
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White matter hyperintensities on magnetic resonance in alzheimer's disease and normal aging| 1990
- 263
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11C-methyl-tetrahydroaminoacridine: a putative ligand for positron-emission tomography of alzheimer's disease| 1990
- 263
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New techniques for the visualization of EEG fourier analysis: comparison of power, coherence and phase patterns between elderly normals and SDAT patients| 1990
- 263
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Neuropsychological predictors of dementia in the old-old| 1990
- 264
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Brain metabolism in alzheimer's dementia — studies of 11C-deoxyglucose accumulation and neuropsychological test performance in patients and healthy control| 1990
- 264
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Cerebral metabolic patterns in alzheimer's disease: A structural explanation| 1990
- 264
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Comparison of EEG background spectral frequency analysis, psychological test scores, short test of mental status, and quantitative spect in alzheimer's disease| 1990
- 264
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Study of the relationship between alzheimer's disease and aluminium in drinking water| 1990
- 265
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Cerebral blood flow and dementia in Parkinson's disease| 1990
- 265
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Periventricular white matter changes in patients with dementia: correlations between magnetic resonance imaging and xenon computerized tomography| 1990
- 265
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The relationship between neuropsychological tests of memory and temporal lobe atrophy in patients with dementia| 1990
- 265
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Magnetic resonance imaging in the Indiana kindred of Gerstmann-Sträussler-Scheinker disease| 1990
- 266
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Entorhinal lesions in dementia| 1990
- 266
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Validation of diagnostic criteria for Alzheimer disease| 1990
- 266
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Psychometrics and their correlations with physical aspects of the Alzheimer brain| 1990
- 266
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Psychopathology and frontal lobe involvement in primary degenerative and vascular dementia. II. Structural background| 1990
- 267
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Hierarchical distribution of Alzheimer pathological changes in the entorhinal cortex and hippocampal formation of patients with down's syndrome of various ages| 1990
- 267
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Alzheimer neurofibillary tangles (NFT) contain triple-stranded left-hand helical filaments which have the same structure as isolated bovine Tau| 1990
- 267
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Kufs' and Alzheimer diseases| 1990
- 268
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Destruction of the entorhinal intracortical axon plexus in alzheimer's disease| 1990
- 268
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Rating of the lesions in senile dementia of the Alzheimer type: Concordance between laboratories| 1990
- 268
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Immuno and routine EM studies on diffuse plaques in the Alzheimer brain| 1990
- 268
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Basic fibroblast growth factor-binding sites in Alzheimer's disease brains| 1990
- 268
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Inter-rater reliability in the diagnosis of Alzheimer's disease| 1990
- 269
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Image analysis microspectroscopy of senile plaques immunostained with an anti beta-protein antibody| 1990
- 269
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Neurofibrillary tangles contain heparan sulfate proteoglycans| 1990
- 269
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Increased chromogranin a/synaptophysin ratio in Alzheimer's and pick's diseases| 1990
- 269
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Senile plaques: Staining for acetylcholinesterase and beta-protein. A comparative study in the entorhinal cortex| 1990
- 270
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Degeneration of corticocortical glutamatergic pathways and its treatment| 1990
- 270
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Normal constitutive processing of the Alzheimer amyloid precursor protein proteolyzes the beta amyloid peptide| 1990
- 270
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Amyloid P component in neurofibrillary tangles, cortical plaques and cerebrospinal fluid in Alzheimer's disease and related disorders| 1990
- 270
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Morphological/neurochemical correlates of depression and psychosis in primary dementia| 1990
- 271
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Selective changes in glutamate receptor subtypes in the Alzheimer cerebellum| 1990
- 271
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Identification of transmembrane Pre A4 protein in brain| 1990
- 271
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Decreased α-adrenergic receptors at the blood-brain barrier (BBB) in Alzheimer's disease (AD)| 1990
- 271
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Reaction of the neuropil to cystatinc C amyloid| 1990
- 272
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The senile plaque: Proposal for a classification and nomenclature| 1990
- 272
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Nigral lewy body degeneration and Alzheimer's disease| 1990
- 272
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Cytoplasmic oligodendroglial inclusions in a patient with striatonigral degeneration, olivopontocerebellar atrophy and “atypical” pick's disease| 1990
- 272
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Rostrocaudal increase of neuropathologic determinants in the nucleus basalis of meynert complex in Alzheimer's disease| 1990
- 273
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In situ hybridization reveals increased muscarinic receptor mRNA in Alzheimer's disease temporal cortex| 1990
- 273
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Stability of dendritic extent of basal forebrain neurons in Alzheimer's disease (AD)| 1990
- 273
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A highly sensitive silver method results in high contrast and fine delineation of the earliest lesions of Alzheimer's disease. Analogous pattern of staining to that of Tau and β-amyloid protein immunocytochemistry| 1990
- 273
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Cholinergic markers in Alzheimer's disease and Parkinson's disease| 1990
- 274
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Unknown type of dementia with grains, threads and complement activated oligodendrocytes| 1990
- 274
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Nerve growth factor receptor levels are reduced in the basal forebrain in Alzheimer's disease| 1990
- 274
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Cortical choline acetyltransferase, phosphate-activated glutaminase, glucuronidase and striatal amines in various dementia syndromes| 1990
- 274
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Senile changes in amyotrophic lateral sclerosis| 1990
- 275
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Basement membrane in forming senile plaque related with amyloid angiopathy of SDAT| 1990
- 275
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Brain bank — a clinico-pathological link in aging and dementia research| 1990
- 275
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Amyloid protein deposits within cerebellum in persons over 80 years of age| 1990
- 275
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The retina and optic nerve in Alzheimer's disease (AD) and aging: A histological and immunocytochemical study| 1990
- 275
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Expression of GFAP and its encoding mRNA in Alzheimer disease| 1990
- 276
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Adult dementia due to intraneuronal accumulation of ceroid- lipofuscinosis (Kufs' disease) : ultrastructural study of two cases| 1990
- 276
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A longitudinal study of Alzheimer dementia in down's syndrome| 1990
- 276
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Clinical diagnosis of Alzheimer dementia in mentally retarded people| 1990
- 277
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Cytoskeletal alterations in the hypothalamus during aging and in Alzheimer's disease| 1990
- 277
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Alzheimer neurofibrillary pathology: A protein phosphorylation/dephosphorylation system defect| 1990
- 277
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Calcium and the neuronal cytoskeleton: Adpative regulation in development and loss of control in neurodegenerative disorders?| 1990
- 277
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Cholinergic trophic factors| 1990
- 278
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Degradation of neurofibrillary tangles in Alzheimer's disease| 1990
- 278
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Histone H1o-mediated repression of neurofilament gene transcription Alzheimer disease| 1990
- 278
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Identification of tau binding proteins| 1990
- 278
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Molecular interaction of 1,2,3,4-tetrahydro-9-amino-acridine (THA), a proposed drug for the treatment of Alzheimer's disease, with the skeletal network of proteins in erythrocyte membranes| 1990
- 278
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Ubiquitin and its association with the neuronal cytoskeleton: Identification of a new map| 1990
- 279
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Nucleolar localization of tau and map-1B epitopes in human neuroblastoma cells| 1990
- 279
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Towards the development of an in vitro study model of Alzheimer-type neurofibrillary degenerationDelacourte, A. / Flament, S. / Défossez, A. et al. | 1990
- 279
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Effect of tau on the exchangeable GTP binding site of brain tubulin in Alzheimer disease| 1990
- 279
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Paired helical filament (PHF) proteins are encoded by exon 1 of tau gene| 1990
- 280
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Posttranslational modifications of tau-related proteins associated with PHFs| 1990
- 280
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Neurofibrillary tangles in the Indiana kindred of Gerstmann-Straussler-Scheinker disease share antigenic determinants with those of Alzheimer disease| 1990
- 280
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Structure, elasticity, and phosphorylation of microtubule-associated protein tau| 1990
- 281
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Proteoglycans and regenerative sprouting of neurites| 1990
- 281
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Ubiquitin carboxyl-terminal hydrolase (PGP9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative disease| 1990
- 281
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Modifications of membrane — β-amyloid precursor protein assemblies in Alzheimer's disease and in squid giant nerve fibers| 1990
- 281
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Abnormally phosphorylated tau isolated from Alzheimer disease brain cytosol is not ubiquitinated| 1990
- 281
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Abnormal phosphorylation of tau precedes ubiquitination in neurofibrillary pathology of Alzheimer disease| 1990
- 282
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Regional distribution of the regulatory (RII) subunit of cAMP-dependent protein kinase II in brain tissue from non-demented and Alzheimer individuals| 1990
- 282
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Aluminum potentiates heat shock protein induction in neuroblastoma cells exposed to hyperthermia| 1990
- 282
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Excitatory aminoacids produce neuronal degeneration with abnormal phosphorylation of neurofilamentsHugon, J. / Vallat, J.M. / Sindou, P. et al. | 1990
- 282
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Near-absence of altered neuropil neurites in cases of “plaque-only” Alzheimer's disease| 1990
- 283
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Antigenicity of tau fragments that remain associated with PHFS after pronase treatment| 1990
- 283
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Dementia in Alzheimer's disease is correlated with dystrophic neurites in temporal isocortex| 1990
- 283
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Amyloid determinants in purified paired helical filaments| 1990
- 283
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Expression of foetal tau into transfected non neuronal cells| 1990
- 284
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Differential distribution of lactoferrin and ALZ-50 immunoreactivities in neuritic plaques and neurofibrillary tangles in Alzheimer's disease (AD)| 1990
- 284
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ALZ-50 immunoreactivity in the hippocampal complex of normal elderly and Alzheimer's diseased brains| 1990
- 284
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The neuronal antigen A68 recognized by ALZ-50 in AD brains is an abnormally phosphorylated tau protein| 1990
- 284
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Alzheimer protein precursors: Tyrosine phosphorylation of the cytoplasmic domainBunke, Dirk / Kypta, Robert M. / Mönning, Ursula / Courtneidge, Sarah A. / Masters, Colin L. / Beyreuther, Konrad T. et al. | 1990
- 285
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Paired helical filaments (PHF) in Alzheimer disease are phosphorylated at multiple sites| 1990
- 285
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Neurofilament gene expression in Alzheimer's disease| 1990
- 285
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The developmental regulation of PHF-1 reactive tau proteins| 1990
- 285
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A casein kinase I activity associated with the A68 proteins from Alzheimer brain| 1990
- 286
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Presence of morphologically distinct A-4 amyloid immunoreactive structure in non-demented elderly and Alzheimer's disease| 1990
- 286
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Na/Ca exchange activity in cerebral plasma membrane vesicles is increased in Alzheimer's disease| 1990
- 286
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Autopsy Alzheimer's brains show increased peroxidation to an in vitro iron challengeRichardson, J.S. / Subbarao, K.V. / Ang, L.C. et al. | 1990
- 286
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Neuronal expression of NF-L in the temporal lobe of Alzheimer brains| 1990
- 287
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Metabolic effects of monoaminergic activation of neurons and glial cells in culture| 1990
- 287
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Elevation of acetylcholinesterase activity in ocular fluids of patients with senile dementia of the Alzheimer typeMcDonald, B. / Appleyard, M.E. et al. | 1990
- 287
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Memory impairment and the neurochemical changes in aged rats and AF-64A treated rats| 1990
- 287
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Alterations in excitatory amino acid concentrations in CSF of patients with Alzheimer's disease| 1990
- 288
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Proteinase inhibitors, leupeptin and Z-prolyl-prolinal, induce neuronal degeneration in primary rat hippocampal neurons in vitro| 1990
- 288
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Acidic fibroblast growth factor-like immunoreactivity in Alzheimer's disease brain tissue| 1990
- 288
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Aluminosilicate — induced free radical generation by murine brain glial cells in vitro: potential pathogenic and nutritional interactions in Alzheimer's dementiaEvans, Peter H. / Peterhans, Ernst / Burge, Thomas / Klinowski, Jacek et al. | 1990
- 288
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Differential expression of members of the heat shock gene family in brain of adult and aged ratsRaese, J.D. / Groshan, K. / Pardue, S. / Border, B. / Miller, E.K. / Morrison-Bogorad, M. et al. | 1990
- 289
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Ultrastructure of isolated cortical lewy bodies| 1990
- 289
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Nucleolar size in hippocampal neurons of Alzheimer's disease patients does not depend from neurofibrillary tangles. Stability of cell size| 1990
- 289
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Cross-cultural studies on dementia: the who-program for research on aging, age-associated dementia| 1990
- 289
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Corticosterone potentiates glutamate toxicity at the NMDA receptor - implications for Alzheimer's disease?| 1990
- 290
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Unifying model for risk factors in Alzheimer disease| 1990
- 290
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Population based studies of aluminium in Alzheimer's disease| 1990
- 290
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Prevalence of dementia and probable Alzheimer's disease in the framingham study| 1990
- 290
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Pilot studies in the N.A.S. registry suggest 60% concordance for Alzheimer's disease in M.Z. twin pairs| 1990
- 290
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The prevalence of dementia in Europe: a collaborative study of 1980–1990 findings| 1990
- 291
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Prevalence of white matter changes in 85-years old. a population study| 1990
- 291
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A comparison of familial vs nonfamilial Alzheimer's disease within a well defined population| 1990
- 291
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Characterization of a 22-derived marker chromosome in a family with late-onset dementia of the Alzheimer type| 1990
- 291
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Brain white-matter lesion and mental function in cerebral infarctionKobayshi, S. / Fukuda, J. / Okada, K. / Koide, H. et al. | 1990
- 292
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The lupus anticoagulant, dementia and antibrain antibodies in non-SLE patients| 1990
- 292
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Distinguishing between the competence and incompetence of individuals with Alzheimer's disease to provide consent for research| 1990
- 292
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Duplicate reporting to a legislatively mandated Alzheimer's disease and other dementias registry| 1990
- 292
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Verification of diagnostic criteria and clinical rating scales in dementia| 1990
- 292
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Survival in senile and presenile Alzheimer's disease| 1990
- 293
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Incidence, prevalence and risk factor analysis of Alheimer's disease in rochester, Minnesota: Long term trends over twenty years| 1990
- 293
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Aging and risk factors for Alzheimer's disease| 1990
- 293
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Biological risk factors for accelerated cognitive aging and dementia: findings from a multiple cohort study| 1990
- 293
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Prevalence of Alzheimer's disease and other dementias in advanced age| 1990
- 294
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Facilitation of pathogenesis of Alzheimer disease by preexisting alcoholic encephalopathy| 1990
- 294
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Age and dementia in the very old| 1990
- 294
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Proportion of genetic cases in dementia of the Alzheimer type (DAT): a new modelTzourio, C / Alperovitch, A / Maccario, J et al. | 1990
- 295
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Dermatoglyphics as a possible genetic marker in dementia of Alzheimer type: A case-control studyBerr, C. / Podrabinek, N. / Feteanu, D. / Taurand, S. / Piette, F. / Alperovitch, A. et al. | 1990
- 295
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Suspected dietary factors in Alzheimer's disease| 1990
- 295
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Alzheimer's disease, Parkinson's disease and smoking| 1990
- 295
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Evidence regarding the effect of prolonged aluminum exposure on cognitive function| 1990
- 296
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Prevalence of a family history of dementia in patients with early and late onset Alzheimer's disease| 1990
- 296
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Alzheimer patients are thinner than matched controls| 1990
- 296
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Risk factors in clinically diagnosed Alzheimer's disease: A case-control study in colombia (South America)| 1990
- 296
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The identification of familial Alzheimer disease cases in the image project population-based registry.| 1990
- 296
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Increased prevalence of neoplasia in autopsy diagnosed Alzheimer's disease| 1990
- 297
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Spanish version of mini-mental state examination (S-MMSE) in diagnosis of dementia: A study in Colombia| 1990
- 297
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Relationships between weight change and survival in cognitively impaired, institutionalized, elderly patients| 1990
- 297
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Clinical course differences between the Alzheimer's and the neurocysticercosis dementias| 1990
- 297
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Assessment of anticipated strategies resources for the Alzheimer's patient report from 685 psychiatrists worldwide the 1988 united nations world population prospects| 1990
- 298
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Predictors of institutionalization among patients with Alzheimer's disease and other dementias| 1990
- 298
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Application of research criteria for dementia in common clinical practice| 1990
- 298
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Familial Alzheimer's disease: study of a new Italian kindred| 1990
- 298
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Differences in postural sway patterns in individuals with Alzheimer disease with and without history of falls: A pilot study| 1990
- 299
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Pathogenesis of beta-amyloid fiber formation| 1990
- 299
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Amyloid β-protein deposition as a seminal pathogenetic event in AD: An hypothesis| 1990
- 299
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Amyloid BA4 protein pathology is central to the cause of Alzheimer's diseaseBeyreuther, K. / Schubert, W. / Multhaup, G. / Salbaum, J.M. / Beer, J. / Hilbich, C. / König, G. / Dyrks, T. / Weidemann, A. / Fischer, P. et al. | 1990
- 299
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Role of immune factors in amyloidogenesis in Alzheimer brain| 1990
- 300
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Mutation in the Alzheimer's disease amyloid gene in patients with hereditary cerebral hemorrhage with amyloidosis - dutch type| 1990
- 300
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Co-occurrence of two amyloid proteins, gelsolin and beta-protein, in a patient with familial amyloidosis, finnish type, and Alzheimer's disease| 1990
- 300
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Soluble derivatives of the β amyloid protein precursor in cerebrospinal fluid are altered in normal aging and to a greater extent in Alzheimer's disease| 1990
- 300
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Cloning and expression of a secreted A4 amyloid peptide precursor| 1990
- 300
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Proteolysis in the formation of amyloid fibrils in Alzheimer's disease| 1990
- 301
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Induced neuronal expression and alternative splicing pattern of the amyloid gene of Alzheimer's diseaseKönig, Gerhard / Masters, Colin L. / Beyreuther, Konrad et al. | 1990
- 301
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Aggregation and amyloidogenicity of fragments of the amyloid A4 protein precursor of Alzheimer's diseaseDyrks, Thomas / Mack-Kühn, Elke / Masters, Colin / Beyreuther, Konrad et al. | 1990
- 301
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The Alzheimer amyloid precursor is produced by type I astrocytes in glial cultures and displays a fibrillary distribution pattern| 1990
- 302
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Possible role of amyloid enhancing factor (ubiquitin) in Alzheimer's disease and reactive amyloidosis| 1990
- 302
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Atypical Gerstmann-Sträussler-Scheinker syndrome with neurofibrillary tangles: No mutation in the prion protein open-reading-frame in a patient of the Indiana kindred| 1990
- 302
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Protease nexin-2/amyloid β-protein precursor: Circulation in blood as a platelet α-granule protein| 1990
- 302
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Amyloid of Alzheimer's disease: Structure-function-relationships and peptide inhibitors of fibril formationHilbich, C. / Kisters-Woike, B. / Reed, J. / Grundt, C. / Masters, C.L. / Franke, W.W. / Beyreuther, K. et al. | 1990
- 303
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Analysis of proteases in cerebrospinal fluid samples from Alzheimer's disease and control patients| 1990
- 303
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Purification of clipsin, an protease which cleaves the β-protein precursor| 1990
- 303
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Studies on a brain protease that cleaves at the N-terminus of β-protein-related synthetic peptides| 1990
- 303
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Transfection of β-amyloid interferes with the differentiation of the cholinergic cell line NG108| 1990
- 303
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Basement membrane heparan sulphate proteoglycan is part of isolated Alzheimer's amyloid plaques| 1990
- 304
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Early accumulation of heparan sulfate in neurons and in the beta-amyloid protein containing lesions of Alzheimer's disease and Down's syndrome| 1990
- 304
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Expression of Alzheimer's disease amyloid precursor protein during post-natal development of rat brain| 1990
- 304
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Indiana kindred of Gerstmann-Sträussler-Scheinker disease: Isolation of low molecular weight protein from amyloid plaque cores| 1990
- 305
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Neuropathology of prospectively studied normal elderly humans| 1990
- 305
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Leukoencephalopathy and cerebral amyloid angiopathy: Clinicopathologic study of two cases| 1990
- 305
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Dementia caused by cerebral amyloid angiopathy associated with hypoperfusion| 1990
- 305
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Amyloid precursor protein (APP) is part of a family of extracellular matrix-like adhesive microfibrils| 1990
- 305
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The organum vasculosum of the lamina terminalis: A contrary model to study the blood-brain barrier in Alzheimer's disease| 1990
- 306
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Release of A4 containing Alzheimer amyloid precursor proteins from membrane damaged, induced, or AD fibroblast-hybridized neural cell cultures| 1990
- 306
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Identification of specific binding sites for 125I secreted APP 751 on intact fibroblast cells| 1990
- 306
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In vitro mutagenesis of the β-amyloid precursor protein| 1990
- 306
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Complement activated oligodendroglia are stained immunohistochemically for amyloid P component| 1990
- 307
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Effects of a novel carbohydrate, 4-deoxy---pentose on neural cell proteoglycan synthesis and function| 1990
- 307
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Morphological characterization of a novel antibody against amyloid enhancing factor| 1990
- 307
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Identification of the secreted form of the 751 amino acid β-amyloid precursor protein in plasma| 1990
- 307
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Induction of amyloid deposition by high molecular weight proteins of the amyloid enhancing factor extracted from brain of patients with Alzheimer's disease| 1990
- 308
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A neurotrophic role for basic fibroblast growth factor (FGF) in Alzheimer's disease| 1990
- 308
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Secreted forms of amyloid β protein precursor in cerebrospinal fluid and sera| 1990
- 308
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A secreted form of the Alzheimer's amyloid precursor protein is a binding protein for transforming growth factor-beta| 1990
- 308
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Amyloid beta protein precursor gene expression in neural and lymphoid cell lines: Influence of DNA cytosine methylation| 1990
- 309
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Differential expression of three types of amyloid β-protein precursor mRNA in the brain and nonneural tissues| 1990
- 309
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Quantitative assessment of gene expression in Alzheimer's disease by PCR amplication of reverse transcribed mRNAs| 1990
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Antibody to β-peptide is lethal for cultured cells| 1990
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Amyloid β protein precursor accumulates in dystrophic neurites of senile plaques in Alzheimer-type dementia| 1990
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A 3-Dimensional structural model of the beta amyloid peptide and fibril of Alzheimer's disease| 1990
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Isolation and characterization of Alzheimer's disease βA4 amyloid precursor protein from human brain| 1990
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Acute phase proteins in amorphous and classical plaques; Differences between vascular and plaque amyloid| 1990
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Synaptic alterations in preamyloid deposits| 1990
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Amyloid precursor protein immunoreactive neurites may be involved in amyloid deposition in the senile plaque| 1990
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The Kunitz protease inhibitory domain of the β-amyloid precursor protein is sufficient for its protease inhibitory properties| 1990
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What role may microglial cells play in plaque formation in Alzheimer's diseaseBehrouz, N. / Defossez, A. / Delacourte, A. / Mazzuca, M. et al. | 1990
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Recombinant vaccinia virus expression of the Alzheimer amyloid precursor (AAP)| 1990
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Amyloidogenesis in Alzheimer's disease (AD): Morphologic association with microglia| 1990
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The two Alzheimer amyloid components and β-protein form a stable complex in vitro| 1990
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Diagnosis of cerebral amyloid angiopathy with the deposition of cystatin C by the use of enzyme-linked immunosorbent assay (ELISA) in cerebrospinal fluid| 1990
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Amyloid protein deposits in the human cerebral cortex: Comparative immunohistochemical studies in Alzheimer's disease and control cases| 1990
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Beta-protein and cystatin C immunoreactivity in amyloid angiopathyBenedikz, E. / Blöndal, H. / Guömundsson, G. et al. | 1990
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C-terminal truncation of APP in cultured mammalian cells occurs within β/A4| 1990
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Increased expression of Alzheimer's disease β-amyloid in senescent cultured fibroblasts| 1990
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Alterations in PC12 cells overexpressing the A4-C terminal region of the amyloid precursor protein| 1990
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The immunocytochemical localization of amyloid β-protein precursor in the mouse brain| 1990
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The effects of aluminum(III) on the integrity of plasmatic membranes: Relevance to Alzheimer's disease| 1990
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Amyotrophic lateral sclerosis parkinsonism dementia complex (ALS-PDC) of Guam as a model of Alzheimer's disease: An overview| 1990
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Marianas dementia: A putative long-latency neurotoxic disorder with features of Alzheimer's disease?| 1990
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Aluminium and the aetiopathogenesis of Alzheimer's disease| 1990
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The zinc deficiency theory for the pathogenesis of neurofibrillary tangles: Possibility of preventive treatment by a zinc compound| 1990
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Chromatographic resolution of aluminum binding components in human serum| 1990
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Effects of aluminum lactate on the stability of linker histone proteins towards DNA : Implications for increased chromatin compaction in Alzheimer's disease| 1990
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Effect of aluminum(III) speciation on the permeability of the blood brain barrier: Possible implications in aluminum intoxication, dialysis and senile dementia| 1990
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New perspectives in metal contamination of health food supplements and antacid tablets and Alzheimer's disease| 1990
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Evidence that lipid peroxidation and total iron are increased in Alzheimer's brain| 1990
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Accumulation of ferritin in Alzheimer disease (AD) brain| 1990
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Calcium and phosphorus in dementiaSubhash, M.N. / Padmashree, T.S. / Srinivas, K.N. / Shankar, S.K. et al. | 1990
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Identification and analysis of senile plaques using nuclear microscopyLandsberg, J.P. / McDonald, B. / Roberts, J.M. / Grime, G.W. / Watt, F. et al. | 1990
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Behavioural and histopathologic changes after intracerebral infusion of Al(malt)3 in the rat| 1990
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Aluminum-induced chronic progressive myelopathy in New Zealand white rabbits| 1990
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The transferrin receptor of cerebral cortex and brain microvessels in Alzheimer's disease and aging| 1990
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Comparative plasma speciation of the aluminium model ‘gallium-67’ in Alzheimers disease, stroke dementia, downs syndrome, end-stage renal disease and controlsFarrar, Gillian / Blair, John A. / Altmann, Paul / Welch, Simon et al. | 1990
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The N-methyl-D-aspartate receptor complex in Alzheimer's disease: Reduced regulation by glycine but not by zinc| 1990
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Plasma levels of anti-oxidant vitamins in patients with Alzheimer's disease (AD)| 1990
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Sulfur-compound metabolism in Alzheimer's disease| 1990
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Linkage analysis of late onset familial Alzheimer's disease| 1990
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RNA metabolism in Alzheimer's disease cerebral cortex. Yield, integrity, and specific message prevalence| 1990
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Molecular genetic investigations of familial Alzheimer disease in a large collaborative data set| 1990
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Alzheimer's disease linked to chromosome 21 in nine families| 1990
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Genetic analysis of chromosome 21 in relation to early onset Alzheimer's disease| 1990
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Extensions of sib-pair linkage tests to disorders with delayed onset: relevance to Alzheimer's disease| 1990
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Genetic linkage studies of familial Alzheimer's disease (FAD)| 1990
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Genetics of Alzheimer's disease| 1990
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Genetic analysis of familial Alzheimer's disease using chromosome 19 and chromosome 21 markers| 1990
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Linkage analysis in familial Alzheimer's disease| 1990
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Risk of dementia in relatives of patients with early onset Alzheimer's disease| 1990
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Gene expression in the brain — A comparative study of control and Alzheimer's disease patients| 1990
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Prion protein gene analysis in pre-senile dementing and ataxic illnesses| 1990
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Chromatin structure and gene expression at the HNF-L gene locus in Alzheimer's disease (AD) affected temporal neocortex| 1990
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Twin study of senile dementia| 1990
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Down syndrome and Alzheimer dementia: Clinical evaluation and genetic associations| 1990
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Age of onset of Alzheimer's disease| 1990
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Processing of precursors of amyloid A4 protein in Alzheimer's diseaseWeidemann, Andreas / Mechler, Hans / Masters, Colin L. / Beyreuther, Konrad et al. | 1990
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Characterization of two blocks of cis-acting regulatory elements modulating the expression of the gene encoding the Alzheimer's amyloid precursor proteins| 1990
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Quantification of growth-associated protein 43 and IL-1β mRNA in normal aging and Alzheimer's disease| 1990
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The common origin of FAD in the Calabria region| 1990
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Reduction of mRNA expression for steroid hormone receptors and calcium binding proteins in Alzheimer brain| 1990
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Use of a chromosome 21 jump clone in linkage analysis of familial Alzheimer's disease (FAD)| 1990
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Construction of a physical map of chromosome 21q in relation to Alzheimer's disease| 1990
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Predominance of A-4 over ALZ-50 positive plaques in non-demented elderly| 1990
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CJD-like agents and human dementias of unknown etiology| 1990
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Molecular biology and transgenetics of prion diseases| 1990
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The prion protein gene, rather than a linked locus, appears to control scrapie incubation period in mice| 1990
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Model systems in Alzheimer's disease| 1990
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Transgenic mice and Alzheimer's diseaseBeer, J. / Salbaum, J.M. / Schlichtmann, E. / Hoppe, P. / Earley, S. / Masters, C.L. / Carlson, G.A. / Beyreuther, K. et al. | 1990
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Ubiquitin conjugate immunoreactivity in the brains of scrapie infected mice| 1990
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Memory dysfunction induced by immunizing rats with the heavy neurofilament protein (NF-H) of Torpedo cholinergic neurons| 1990
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Trisomy 16 mouse model of Alzheimer's disease| 1990
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Relationship between electrocortical arousal and memory deficits in aged rats - effects of atipamezole alpha-2 antagonist| 1990
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Transplants of mouse trisomy 16 hippocampus provide an in vivo model of the neuropathology of Alzheimer's disease| 1990
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Microglia activation in scrapie-induced amyloidosis in murine CNS| 1990
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Effects of combined intracerebroventricular infusion of choline and oral administration of cholinergic drugs on learning impairment in ventral globus pallidus-lesioned rats| 1990
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Loss of hippocampal neurons after chronic brain hypoperfusion in aged rats| 1990
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Astroglial gene expression in response to hippocampal deafferentation in the rat and in Alzheimer's disease| 1990
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The induction of cognitive deficits by immunization with cholinergic cell bodies: The influence of age and integrity of the blood brain barrier| 1990
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Long-term nucleus basalis lesions in the aging rat induce cortical dendritic hypertrophy accompanied by spine loss| 1990
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Pharmacology of tacrine: Contribution of cholinergic and noncholinergic actions| 1990
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Complete homology of the amyloid β-protein precursor in monkey and human: Support for a primate model of β-amyloidosis| 1990
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Reversal of lesion-induced memory deficits and enhancement of a cholinergic marker by chromaffin cell grafts to rat cerebral cortex| 1990
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incorporation of (C-14) N-acetylmannosamine into brain gangliosides in hypocholinergic rats| 1990
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Morphometry of aged dogs brains| 1990
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Neurotransmitter actions on dentate gyrus (DG) neurons of aged rats| 1990
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Protease inhibitor, leupeptin, causes irreversible axonal changes in rats| 1990
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The βA4 amyloid protein and its precursors as biological markers for Alzheimer's diseaseMasters, Colin L. / Bush, Ashley / Evin, Genevieve / Fuller, Stephanie / Li, Quao-Xin / Mackenzie, Ian / Milward, Elizabeth / Moir, Robert / Small, David / Beyreuther, Konrad et al. | 1990
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Neurotransmitter markers in the cerebrospinal fluid of patients with histologically verified Alzheimer's disease| 1990
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Brain nicotinic receptor deficits in Alzheimer patients as studied by positron emission tomography technique| 1990
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Impairments in cellular fibrous proteins: Biologic marker for Alzheimer disease?| 1990
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Alzheimer cytoskeletal pathology: From microtubule associated protein tau to paired helical filaments| 1990
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Temporal versus frontal changes in Alzheimer's disease associated proteins — A biochemical study| 1990
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Increased level of paired helical filament (PHF) antigens in CSF from patients with subacute sclerosinc panencephalitis (SSPE)| 1990
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Detection of circulating forms of the amyloid β-protein precursor (APP) in human plasma| 1990
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Tissue culture model systems for the study of Alzheimer's disease| 1990
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The amyloid precursor protein of Alzheimer's disease is released by human platelets| 1990
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and antitrypsin in CSF of patients with dat| 1990
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Quantitative determination of the amyloid A4 precursor protein in cerebrospinal fluidPrior, R. / Mönning, U. / Weidemann, A. / Fischer, P. / Blennow, K. / Gottfries, C.G. / Beyreuther, K. et al. | 1990
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CSF α 1-antichymotrypsin level is elevated in patients with Alzheimer-type dementia| 1990
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Higher platelet internal membrane fluidity in Alzheimer's patients versus controls| 1990
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Somatostatin-like immunoreactivity and neurotransmitter metabolites in the cerebrospinal fluid of patients with senile dementia of Alzheimer's type and multiinfarkt dementia| 1990
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Platelet membrane fluidity differences in Alzheimer's cases and controls| 1990
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Biological marker for cerebral ischemia in Alzheimer's disease| 1990
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Specific changes in erythrocyte membrane characteristics indicate disturbance of the cellular aging process in Alzheimer's disease| 1990
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Abnormal calcium homeostasis in platelets isolated from Alzheimer's disease patients| 1990
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Zinc and thymic hormone involution in Alzheimer's disease| 1990
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Enhanced expression of an exocrine pancreatic protein in Alzheimer's disease and the developing human brain| 1990
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Normal lactate production and altered hexokinase activity in fibroblasts and leukocytes from familial Alzheimer's disease patients| 1990
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Vitamins, metals and routine bloodchemistry in normal aging: Results from a multiple cohort study| 1990
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The EEG spectra of Alzheimer's disease| 1990
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Correlations between and among purines and purine metabolites in Alzheimer's disease| 1990
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Different patterns of CSF monoamine metabolites in old-age dementias| 1990
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Automatic changes in semantic priming in early Alzheimer's disease| 1990
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Distribution of Alzheimer disease associated proteins in 10 human brains| 1990
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The sleep EEG: A biomarker for mild Alzheimer's disease and cognitive decline| 1990
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Circadian temperature and locomotor activity rhythms in Alzheimer's disease| 1990
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Immunoreactivity to beta-amyloid protein in the skins of AD and DS people| 1990
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Alzheimer amyloid BA4-protein reactive antibodies in human sera and CSFMönning, U. / Schreiter-Gasser, U. / Hilbich, C. / Bunke, D. / Prior, R. / Masters, C.L. / Beyreuther, K. et al. | 1990
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Detection of amyloid beta protein precursor immunoreactivity in normal and Alzheimer's disease cerebrospinal fluid| 1990
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Are alpha-1-antichymotrypsin and inter-alpha-trypsin inhibitor peripheral markers of Alzheimer's disease?Furby, A. / Leys, D. / Delacourte, A. / Buée, L. / Soetart, G. / Petit, H. et al. | 1990
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Philothermal response and oligoelements in patients with Alzheimer's disease| 1990
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Immunological parameters in patients with Alzheimer's disease| 1990
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Integrin expression in Alzheimer brain tissue| 1990
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Fetal and adult brain tissue as a substrate to examine antibodies in the CSF from dementia patients| 1990
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Quantitative autoradiography of protein kinase C levels in Alzheimer's disease| 1990
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Longitudinal evaluation of the rate of change in Alzheimer's disease| 1990
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Alterations of the cholinergic system in Alzheimer's and Parkinson's diseases| 1990
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Opioid peptides and reticular mechanisms in neurodegenerative disease| 1990
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New cholinesterase inhibitors for treatment of Alzheimer. Pharmacological and clinical aspects| 1990
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Canadian therapeutic trials for Alzheimer's disease in the 80's: Lessons for the 90's| 1990
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Serotonin, learning, memory, and Alzheimer's disease| 1990
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Implications of normal volunteer compared to patient studies in the early evaluation of compounds for Alzheimer's disease (AD)| 1990
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L-acetylcarnitine and Alzheimer's disease: Results of a controlled clinical trial| 1990
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Comparison of biochemical and behavioral effects of THA and some of its analogues on the cholinergic system| 1990
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The effect of THA on cognitive functions and spectral power EEG in AD| 1990
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Molecular shuttle chelation - studies on desferrioxamine based chelation of aluminum for neurobiological applications: Alzheimer's disease| 1990
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Evaluation of MU rhythm in Alzheimer's disease| 1990
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Serotonin disturbances in Alzheimer's disease, their relation to emotional symptoms and aspects on treatment| 1990
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Postural blood pressure drop as a possible predictor of response to cholinergic therapy in Alzheimer's disease| 1990
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Operant techniques — For behavior management in Alzheimer's disease| 1990
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Phosphatidylserine restores spatial memory and morphofunctional cholinergic markers in basal forebrain nuclei of aged rats| 1990
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Tetrahydroaminoacridine (THA) in Alzheimer's dementia — clinical and biochemical results of a double-blind cross over trial| 1990
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Temperature-dependent effects of tacrine on cholinergic transmission| 1990
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Basic fibroblast growth factor (bFGF) protects hippocampal cholinergic neurons against lesion induced by the neurotoxin AF64A| 1990
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Correspondence and divergence of objective measures of memory with observational methods of behavior appraisal in clinical trials of patients with primary degenerative dementia| 1990
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Pharmacokinetics of galanthamine in humans and corresponding cholinesterase inhibition| 1990
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Acetyl-l-carnitine activity in senile dementia Alzheimer type| 1990
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Differential physiologic and neuroendocrine response to naloxone in subjects with Alzheimer's disease and age-matched controls| 1990
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The process of dying with Alzheimer's disease and caregiver bereavement| 1990
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Therapeutic potential of thyrotropin-releasing hormone (TRH) and lecithin co-administration in Alzheimer's disease| 1990
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Nerve growth factor reduces age-related functional cognitive deficits in rats: Correlation with biochemical forebrain cholinergic markers| 1990
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Brain protection of nicergoline against hypoxia: EEG brain mapping and psychometry| 1990
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The therapy (combination of conezym Q10, Vitamin B6. With iron) for Alzheimer's disease and senile dementia of the Alzheimer type| 1990
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Searching for electrophysiological markers of pharmacological activity: A pilot study with phosphatidylserine on SDAT patients| 1990
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Double blind trial of a tacrine/lecithin combination-preliminary analysis| 1990
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Effect of the cholinesterase inhibitor huperzine A (HUP-A) on central cholinergic parameters in the rat| 1990
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Double-blind placebo-controlled DGAVP in early Alzheimer's disease patients| 1990
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The effects of Alzheimer's disease on driving-related abilities| 1990
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Oral tetrahydroaminoacridine and lecithin treatment of Alzheimer's disease| 1990
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Regional Alzheimer's disease program: Development of a model center for a relatively underserved population in the central United States| 1990
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The effect of tacrine and selected metabolites on rat acetyl- and butyrylcholinesterase activity| 1990
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Innovative research methodologies in normal aging and memory: An international survey| 1990
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Effects of scopolamine on lateralization of 40Hz EEG activity in young healthy volunteers| 1990
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The importance of oral health and nutrition for patients with Alzheimer type dementia and related disorders| 1990
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Two years experiences in SDAT treatment with Ginkgo biloba extract| 1990
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Nursing care of demented patients in a group living| 1990
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Antibodies recognizing intracellular epitopes of amyloid BA4 protein and the amyloid precursor protein of Alzheimer's disease| 1990
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Clinical experience with a cholinesterase inhibitor (HP 029) in the treatment of Alzheimer's disease: Can it make a difference?| 1990
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Levels of NGF and chat in the central cholinergic system of aged learning-impaired rats are resembled by streptozotocin-induced damage of brain glucose metabolism and learning abilities in adult rats| 1990
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Effects of idebenone on acetylcholine in AF64A-treated ratsEndo, H. / Kuzuya, F. / Goto, T. / Tajima, T. / Ikari, H. et al. | 1990
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Clinical differences between early- and late-onset subtypes of Alzheimer's disease| 1990
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Author index| 1990