Crosstalk - The PIK related kinases intercept conventional signaling pathways - Early efforts to place the first cloned mammalian PIK-related kinase, FRAP, into a conventional membrane to nuclear pathway met with little success. More recent data suggest that members of the family of PIK-related kinases act as intracellular sensors that govern radial and horizontal pathways. These pathways can impinge upon classical membrane to nuclear pathways, as well as components of the cell-cycle machinery (English)
- New search for: Kuruvilla, Finny G.
- New search for: Kuruvilla, Finny G.
- New search for: Schreiber, Stuart L.
In:
Chemistry & biology
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6
, 5
; R129
;
1999
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ISSN:
- Article (Journal) / Print
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Title:Crosstalk - The PIK related kinases intercept conventional signaling pathways - Early efforts to place the first cloned mammalian PIK-related kinase, FRAP, into a conventional membrane to nuclear pathway met with little success. More recent data suggest that members of the family of PIK-related kinases act as intracellular sensors that govern radial and horizontal pathways. These pathways can impinge upon classical membrane to nuclear pathways, as well as components of the cell-cycle machinery
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Contributors:Kuruvilla, Finny G. ( author ) / Schreiber, Stuart L.
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Published in:Chemistry & biology ; 6, 5 ; R129
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Publisher:
- New search for: Cell Press
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Place of publication:Cambridge, Massachusetts
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Publication date:1999
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 42.13 / 44.42
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Source:
Table of contents – Volume 6, Issue 5
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 265
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Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D~3Boehm, M. F. / Fitzgerald, P. / Zou, A. / Elgort, M. G. / Bischoff, E. D. / Mere, L. / Mais, D. E. / Bissonnette, R. P. / Heyman, R. A. / Nadzan, A. M. et al. | 1999
- 265
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Research Papers - Novel nonsecosteroidal vitamin D mimics exert VDR-modulating activities with less calcium mobilization than 1,25-dihydroxyvitamin D3 -Boehm, Marcus F. et al. | 1999
- 277
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Research Papers - Calories from carbohydrates: Energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibitionBailly, Christian et al. | 1999
- 277
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Calories from carbohydrates: energetic contribution of the carbohydrate moiety of rebeccamycin to DNA binding and the effect of its orientation on topoisomerase I inhibitionBailly, C. / Qu, X. / Graves, D. E. / Prudhomme, M. / Chaires, J. B. et al. | 1999
- 287
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Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiaeButler, A. R. / Bate, N. / Cundliffe, E. et al. | 1999
- 287
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Research Papers - Impact of thioesterase activity on tylosin biosynthesis in Streptomyces fradiaeButlér, Andrew R. et al. | 1999
- 293
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Research Papers - The amyloidogenicity of gelsolin is controlled by proteolysis and pHRatnaswamy, Gayathri et al. | 1999
- 293
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The amyloidogenicity of gelsolin is controlled by proteolysis and pHRatnaswamy, G. / Koepf, E. / Bekele, H. / Yin, H. / Kelly, J. W. et al. | 1999
- 305
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In vivo processing and antibiotic activity of microcin B17 analogs with varying ring content and altered bisheterocyclic sitesRoy, R. S. / Kelleher, N. L. / Milne, J. C. / Walsh, C. T. et al. | 1999
- 305
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Research Papers - In vivo processing and antibiotic activity of microcin B17 analogs with varying ring content and altered bisheterocyclic sitesRoy, Ranabir Sinha et al. | 1999
- 319
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Research Papers - Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthaseTondi, Donatella et al. | 1999
- 319
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Structure-based discovery and in-parallel optimization of novel competitive inhibitors of thymidylate synthaseTondi, D. / Slomczynska, U. / Costi, M. P. / Watterson, D. M. / Ghelli, S. / Shoichet, B. K. et al. | 1999
- R129
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The PIK-related kinases intercept conventional signaling pathwaysKuruvilla, F. G. / Schreiber, S. L. et al. | 1999
- R137
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Touching the heart of HIV-1 drug resistance: the fingers close down on the dNTP at the polymerase active siteSarafianos, S. G. / Das, K. / Ding, J. / Boyer, P. L. / Hughes, S. H. / Arnold, E. et al. | 1999
- R147
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Delicious vaccines: Axis Genetics, plcWells, W. A. et al. | 1999
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Elsewhere in Biology - A selection of interesting papers published last month in Chemistry & Biology's sister journals, Current Biology and Structure with Folding & Design| 1999
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Calendar| 1999
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Crosstalk - The PIK related kinases intercept conventional signaling pathways - Early efforts to place the first cloned mammalian PIK-related kinase, FRAP, into a conventional membrane to nuclear pathway met with little success. More recent data suggest that members of the family of PIK-related kinases act as intracellular sensors that govern radial and horizontal pathways. These pathways can impinge upon classical membrane to nuclear pathways, as well as components of the cell-cycle machineryKuruvilla, Finny G. et al. | 1999
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Web alert| 1999
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Minireview - Touching the heart of HIV-1 drug resistance: The finger close down on the dNTP at the polymerase active site - Comparison of the recently solved structure of HIV-1 reverse transcriptase (RT)-DNA-dNTP ternary complex with the previously solved structure of RT-DNA binary complex suggests mechanisms by which the HIV-1 RT becomes resistant to nucleoside-analog inhibitors, drugs currently used in the treatment of AIDSSarafianos, Stefan G. et al. | 1999
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Instructions to authors| 1999
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Innovations - Delicious vaccines: Axis Genetics, plcWells, William A. et al. | 1999
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Erratum - Structural and functional organization of the fengycin synthetase multienzyme system from Bacillus subtilis b213 and A1-3Steller, Sigrid et al. | 1999
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Product News| 1999