Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors (English)
- New search for: Xu, Liping
- New search for: Xu, Liping
- New search for: Vagner, Josef
- New search for: Alleti, Ramesh
- New search for: Rao, Venkataramanarao
- New search for: Jagadish, Bhumasamudram
- New search for: Morse, David L.
- New search for: Hruby, Victor J.
- New search for: Gillies, Robert J.
- New search for: Mash, Eugene A.
In:
Bioorganic & medicinal chemistry letters
;
20
, 8
; 2489-2493
;
2010
-
ISSN:
- Article (Journal) / Print
-
Title:Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptors
-
Contributors:
-
Published in:Bioorganic & medicinal chemistry letters ; 20, 8 ; 2489-2493
-
Publisher:
- New search for: Elsevier
-
Place of publication:Amsterdam [u.a.]
-
Publication date:2010
-
ISSN:
-
ZDBID:
-
Type of media:Article (Journal)
-
Type of material:Print
-
Language:English
- New search for: 35.70 / 44.33 / 44.42
- Further information on Basic classification
-
Keywords:
-
Classification:
-
Source:
Table of contents – Volume 20, Issue 8
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2391
-
Graphical contents list| 2010
- 2408
-
Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitorHeffron, Timothy P. / Berry, Megan / Castanedo, Georgette / Chang, Christine / Chuckowree, Irina / Dotson, Jennafer / Folkes, Adrian / Gunzner, Janet / Lesnick, John D. / Lewis, Cristina et al. | 2010
- 2412
-
Homoisoflavonoid derivatives from the roots of Ophiopogon japonicus and their in vitro anti-inflammation activityHung, Tran Manh / Thu, Cao Van / Dat, Nguyen Tien / Ryoo, Sung-Woo / Lee, Jeong Hyung / Kim, Jin Cheol / Na, Minkyun / Jung, Hyun-Ju / Bae, KiHwan / Min, Byung Sun et al. | 2010
- 2417
-
Antioxidant and antiproliferative activities of hydroxyl-substituted Schiff basesCheng, Li-Xia / Tang, Jiang-Jiang / Luo, Hui / Jin, Xiao-Ling / Dai, Fang / Yang, Jie / Qian, Yi-Ping / Li, Xiu-Zhuang / Zhou, Bo et al. | 2010
- 2421
-
Synthesis and SOD activity of manganese complexes of substituted pyridino pentaaza macrocycles that contain axial auxiliaryLee, Hakyoung / Park, Wonchoul / Lim, Dongyeol et al. | 2010
- 2425
-
γ-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonistsCherney, Robert J. / Mo, Ruowei / Meyer, Dayton T. / Voss, Matthew E. / Yang, Michael G. / Santella, Joseph B. III / Duncia, John V. / Lo, Yvonne C. / Yang, Gengjie / Miller, Persymphonie B. et al. | 2010
- 2425
-
g-Lactams as glycinamide replacements in cyclohexane-based CC chemokine receptor 2 (CCR2) antagonistsCherney, R. J. / Mo, R. / Meyer, D. T. / Voss, M. E. / Yang, M. G. / Santella, J. B. / Duncia, J. V. / Lo, Y. C. / Yang, G. / Miller, P. B. et al. | 2010
- 2431
-
B-Raf kinase inhibitors: Hit enrichment through scaffold hoppingGopalsamy, Ariamala / Shi, Mengxiao / Hu, Yongbo / Lee, Frederick / Feldberg, Larry / Frommer, Eileen / Kim, Steven / Collins, Karen / Wojciechowicz, Donald / Mallon, Robert et al. | 2010
- 2435
-
Tetrahydropyridine derivatives with inhibitory activity on the production of proinflammatory cytokines: Part 2Nakao, Akira / Ohkawa, Nobuyuki / Nagasaki, Takayoshi / Kagari, Takashi / Doi, Hiromi / Shimozato, Takaichi / Ushiyama, Shigeru / Aoki, Kazumasa et al. | 2010
- 2438
-
Spectacular modification of Gambogic acid on microwave irradiation in methanol: Isolation and structure identification of two products with potent anti-tumor activityWang, Xiaojian / Lu, Na / Yang, Qian / Dai, Qinsheng / Tao, Lei / Guo, Xiaoke / Guo, Qinglong / You, Qidong et al. | 2010
- 2443
-
Synthesis and evaluation of alkenyl indazoles as selective Aurora kinase inhibitorsBlanchard, Stéphanie / William, Anthony D. / Lee, Angeline C.-H. / Poulsen, Anders / Teo, Ee Ling / Deng, Weiping / Tu, Noah / Tan, Evelyn / Goh, Kay Lin / Ong, Wai Chung et al. | 2010
- 2448
-
Towards biomarker-dependent individualized chemotherapy: Exploring cell-specific differences in oxaliplatin–DNA adduct distribution using accelerator mass spectrometryHah, Sang Soo / Henderson, Paul T. / Turteltaub, Kenneth W. et al. | 2010
- 2452
-
Imidazo[2,1-b]thiazoles: Multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinasesFidanze, Steve D. / Erickson, Scott A. / Wang, Gary T. / Mantei, Robert / Clark, Richard F. / Sorensen, Bryan K. / Bamaung, Nwe Y. / Kovar, Peter / Johnson, Eric F. / Swinger, Kerren K. et al. | 2010
- 2456
-
Antimicrobial selaginellin derivatives from Selaginella pulvinataCao, Yuan / Chen, Ji-Jun / Tan, Ning-Hua / Oberer, Lukas / Wagner, Trixie / Wu, Yong-Ping / Zeng, Guang-Zhi / Yan, He / Wang, Qiang et al. | 2010
- 2461
-
Design, synthesis, and antibiofilm activity of 2-arylimino-3-aryl-thiazolidine-4-onesPan, Bin / Huang, Ren-Zheng / Han, Shi-Qing / Qu, Di / Zhu, Ming-Li / Wei, Ping / Ying, Han-Jie et al. | 2010
- 2465
-
The development and validation of a novel virtual screening cascade protocol to identify potential serotonin 5-HT7R antagonistsKurczab, Rafał / Nowak, Mateusz / Chilmonczyk, Zdzisław / Sylte, Ingebrigt / Bojarski, Andrzej J. et al. | 2010
- 2469
-
Rational design of a pirinixic acid derivative that acts as subtype-selective PPARγ modulatorThieme, Theresa M. / Steri, Ramona / Proschak, Ewgenij / Paulke, Alexander / Schneider, Gisbert / Schubert-Zsilavecz, Manfred et al. | 2010
- 2469
-
Rational design of a pirinixic acid derivative that acts as subtype-selective PPARg modulatorThieme, T. M. / Steri, R. / Proschak, E. / Paulke, A. / Schneider, G. / Schubert-Zsilavecz, M. et al. | 2010
- 2474
-
A-ring modifications on the triazafluorenone core structure and their mGluR1 antagonist propertiesSasikumar, T.K. / Qiang, Li / Burnett, Duane A. / Greenlee, William J. / Li, Cheng / Grilli, Mariagrazia / Bertorelli, Rosalia / Lozza, Gianluca / Reggiani, Angelo et al. | 2010
- 2478
-
A novel d-glucose derivative radiolabeled with technetium-99m: Synthesis, biodistribution studies and scintigraphic images in an experimental model of Ehrlich tumorde Barros, André Luís Branco / Cardoso, Valbert Nascimento / Mota, Luciene das Graças / Leite, Elaine Amaral / de Oliveira, Mônica Cristina / Alves, Ricardo José et al. | 2010
- 2481
-
Praziquantel analogs with activity against juvenile Schistosoma mansoniDong, Yuxiang / Chollet, Jacques / Vargas, Mireille / Mansour, Nuha R. / Bickle, Quentin / Alnouti, Yazen / Huang, Jiangeng / Keiser, Jennifer / Vennerstrom, Jonathan L. et al. | 2010
- 2485
-
Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternativesLeung, Cheryl S. / Zeevaart, Jacob G. / Domaoal, Robert A. / Bollini, Mariela / Thakur, Vinay V. / Spasov, Krasimir A. / Anderson, Karen S. / Jorgensen, William L. et al. | 2010
- 2489
-
Synthesis and characterization of a Eu-DTPA-PEGO-MSH(4) derivative for evaluation of binding of multivalent molecules to melanocortin receptorsXu, Liping / Vagner, Josef / Alleti, Ramesh / Rao, Venkataramanarao / Jagadish, Bhumasamudram / Morse, David L. / Hruby, Victor J. / Gillies, Robert J. / Mash, Eugene A. et al. | 2010
- 2493
-
Discovery of triarylethanolamine inhibitors of the Kv1.5 potassium channelBeshore, Douglas C. / Liverton, Nigel J. / McIntyre, Charles J. / Claiborne, Christopher F. / Libby, Brian / Culberson, J. Christopher / Salata, Joseph J. / Regan, Christopher P. / Lynch, Joseph J. / Kiss, Laszlo et al. | 2010
- 2497
-
Identification of very potent inhibitor of human aminopeptidase N (CD13)Grzywa, Renata / Oleksyszyn, Józef / Salvesen, Guy S. / Drąg, Marcin et al. | 2010
- 2500
-
Natural products-based insecticidal agents 5. Design, semisynthesis and insecticidal activity of novel 4′-substituted benzenesulfonate derivatives of 4-deoxypodophyllotoxin against Mythimna separata Walker in vivoXu, Hui / Wang, Juan-Juan et al. | 2010
- 2500
-
Natural products-based insecticidal agents 5. Design, semisynthesis and insecticidal activity of novel 4prime-substituted benzenesulfonate derivatives of 4-deoxypodophyllotoxin against Mythimna separata Walker in vivoXu, H. / Wang, J. J. et al. | 2010
- 2503
-
N-Aryltriazole ribonucleosides with potent antiproliferative activity against drug-resistant pancreatic cancerLiu, Yang / Xia, Yi / Fan, Yuting / Maggiani, Alain / Rocchi, Palma / Qu, Fanqi / Iovanna, Juan L. / Peng, Ling et al. | 2010
- 2508
-
Carbonic anhydrase inhibitors. The β-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamidesGüzel, Özlen / Maresca, Alfonso / Hall, Rebecca A. / Scozzafava, Andrea / Mastrolorenzo, Antonio / Mühlschlegel, Fritz A. / Supuran, Claudiu T. et al. | 2010
- 2508
-
Carbonic anhydrase inhibitors. The b-carbonic anhydrases from the fungal pathogens Cryptococcus neoformans and Candida albicans are strongly inhibited by substituted-phenyl-1H-indole-5-sulfonamidesGuzel, O. / Maresca, A. / Hall, R. A. / Scozzafava, A. / Mastrolorenzo, A. / Muhlschlegel, F. A. / Supuran, C. T. et al. | 2010
- 2512
-
Synthesis and biological evaluation of piperazinyl heterocyclic antagonists of the gonadotropin releasing hormone (GnRH) receptorVera, Matthew D. / Lundquist, Joseph T. IV / Chengalvala, Murty V. / Cottom, Joshua E. / Feingold, Irene B. / Garrick, Lloyd M. / Green, Daniel M. / Hauze, Diane B. / Mann, Charles W. / Mehlmann, John F. et al. | 2010
- 2516
-
Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonistsCramp, Sue / Dyke, Hazel J. / Higgs, Christopher / Clark, David E. / Gill, Matthew / Savy, Pascal / Jennings, Neil / Price, Steve / Lockey, Peter M. / Norman, Dennis et al. | 2010
- 2520
-
Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonistsEvindar, Ghotas / Bernier, Sylvie G. / Doyle, Elisabeth / Kavarana, Malcolm J. / Satz, Alexander L. / Lorusso, Jeanine / Blanchette, Heather S. / Saha, Ashis K. / Hannig, Gerhard / Morgan, Barry A. et al. | 2010
- 2525
-
Synthesis, cytotoxic activity and structure–activity relationships of hedychenone analoguesPrabhakar Reddy, P. / Lavekar, Aditya G. / Suresh Babu, K. / Ranga Rao, R. / Shashidhar, J. / Shashikiran, G. / Madhusudana Rao, J. et al. | 2010
- 2529
-
[11C]Dimebon, radiosynthesis and lipophilicity of a new potential PET agent for imaging of Alzheimer’s disease and Huntington’s diseaseGao, Mingzhang / Wang, Min / Hutchins, Gary D. / Zheng, Qi-Huang et al. | 2010
- 2533
-
Heterocyclic fused pyridone carboxylic acid M1 positive allosteric modulatorsKuduk, Scott D. / Di Marco, Christina N. / Chang, Ronald K. / Ray, William J. / Ma, Lei / Wittmann, Marion / Seager, Matthew A. / Koeplinger, Kenneth A. / Thompson, Charles D. / Hartman, George D. et al. | 2010
- 2538
-
Hydroxy cycloalkyl fused pyridone carboxylic acid M1 positive allosteric modulatorsKuduk, Scott D. / DiPardo, Robert M. / Beshore, Douglas C. / Ray, William J. / Ma, Lei / Wittmann, Marion / Seager, Matthew A. / Koeplinger, Kenneth A. / Thompson, Charles D. / Hartman, George D. et al. | 2010
- 2542
-
Benzyl prolinate derivatives as novel selective KCC2 blockersPégurier, Cécile / Bosman, Nathalie / Collart, Philippe / Delporte, Marie-Laure / Leclercq, Karine / Lengelé, Sébastien / Kanduluru, Ananda Kumar / Meunier, Stéphane / Pacico, Nathalie / Vadali, Lakshmana Rao et al. | 2010
- 2546
-
Chemopreventive activities of etodolac and oxyphenbutazone against mouse skin carcinogenesisKapadia, Govind J. / Azuine, Magnus A. / Shigeta, Yuuko / Suzuki, Nobutaka / Tokuda, Harukuni et al. | 2010
- 2549
-
Curcumin derivatives inhibit testicular 17β-hydroxysteroid dehydrogenase 3Hu, Guo-Xin / Liang, Guang / Chu, Yanhui / Li, Xiaokun / Lian, Qing-Quang / Lin, Han / He, Yi / Huang, Yadong / Hardy, Dianne O. / Ge, Ren-Shan et al. | 2010
- 2549
-
Curcumin derivatives inhibit testicular 17b-hydroxysteroid dehydrogenase 3Hu, G. X. / Liang, G. / Chu, Y. / Li, X. / Lian, Q. Q. / Lin, H. / He, Y. / Huang, Y. / Hardy, D. O. / Ge, R. S. et al. | 2010
- 2552
-
Discovery of a new series of Aurora inhibitors through truncation of GSK1070916Medina, Jesus R. / Grant, Seth W. / Axten, Jeffrey M. / Miller, William H. / Donatelli, Carla A. / Hardwicke, Mary Ann / Oleykowski, Catherine A. / Liao, Qiaoyin / Plant, Ramona / Xiang, Hong et al. | 2010
- 2556
-
Amide-based inhibitors of p38a MAP kinase. Part 1: Discovery of novel N-pyridyl amide lead moleculesLuedtke, G. R. / Schinzel, K. / Tan, X. / Tester, R. W. / Nashashibi, I. / Xu, Y. j. / Dugar, S. / Levy, D. E. / Jung, J. et al. | 2010
- 2556
-
Amide-based inhibitors of p38α MAP kinase. Part 1: Discovery of novel N-pyridyl amide lead moleculesLuedtke, Gregory R. / Schinzel, Kurt / Tan, Xuefei / Tester, Richland W. / Nashashibi, Imad / Xu, Yong-jin / Dugar, Sundeep / Levy, Daniel E. / Jung, Joon et al. | 2010
- 2560
-
Amide-based inhibitors of p38α MAP kinase. Part 2: Design, synthesis and SAR of potent N-pyrimidyl amidesTester, Richland / Tan, Xuefei / Luedtke, Gregory R. / Nashashibi, Imad / Schinzel, Kurt / Liang, Weiling / Jung, Joon / Dugar, Sundeep / Liclican, Albert / Tabora, Jocelyn et al. | 2010
- 2560
-
Amide-based inhibitors of p38a MAP kinase. Part 2: Design, synthesis and SAR of potent N-pyrimidyl amidesTester, R. / Tan, X. / Luedtke, G. R. / Nashashibi, I. / Schinzel, K. / Liang, W. / Jung, J. / Dugar, S. / Liclican, A. / Tabora, J. et al. | 2010
- 2564
-
The effect of the pyridyl nitrogen position in pyridylpiperazine sigma ligandsStavitskaya, Lidiya / Seminerio, Michael J. / Matthews-Tsourounis, Marilyn M. / Matsumoto, Rae R. / Coop, Andrew et al. | 2010
- 2566
-
NGF-potentiating vibsane-type diterpenoids from Viburnum sieboldiiKubo, Miwa / Kishimoto, Yoshiko / Harada, Kenichi / Hioki, Hideaki / Fukuyama, Yoshiyasu et al. | 2010
- 2572
-
Identification of potent, highly constrained CGRP receptor antagonistsStump, Craig A. / Bell, Ian M. / Bednar, Rodney A. / Fay, John F. / Gallicchio, Steven N. / Hershey, James C. / Jelley, Richard / Kreatsoulas, Constantine / Moore, Eric L. / Mosser, Scott D. et al. | 2010
- 2577
-
2,5-Disubstituted pyridines as potent GPR119 agonistsWu, Yulin / Kuntz, Judith D. / Carpenter, Andrew J. / Fang, Jing / Sauls, Howard R. / Gomez, Daniel J. / Ammala, Carina / Xu, Yun / Hart, Shane / Tadepalli, Sarva et al. | 2010
- 2582
-
Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT2-selective melatonin ligandsHu, Yueqing / Ho, Maurice K.C. / Chan, King H. / New, David C. / Wong, Yung H. et al. | 2010
- 2586
-
Novel benzofuran-3-one indole inhibitors of PI3 kinase-α and the mammalian target of rapamycin: Hit to lead studiesBursavich, Matthew G. / Brooijmans, Natasja / Feldberg, Lawrence / Hollander, Irwin / Kim, Stephen / Lombardi, Sabrina / Park, Kaapjoo / Mallon, Robert / Gilbert, Adam M. et al. | 2010
- 2586
-
Novel benzofuran-3-one indole inhibitors of PI3 kinase-a and the mammalian target of rapamycin: Hit to lead studiesBursavich, M. G. / Brooijmans, N. / Feldberg, L. / Hollander, I. / Kim, S. / Lombardi, S. / Park, K. / Mallon, R. / Gilbert, A. M. et al. | 2010
- 2591
-
Design and synthesis of tricyclic sulfones as γ-secretase inhibitors with greatly reduced Notch toxicityXu, Ruo / Cole, David / Asberom, Ted / Bara, Tom / Bennett, Chad / Burnett, Duane A. / Clader, John / Domalski, Martin / Greenlee, William / Hyde, Lynn et al. | 2010
- 2591
-
Design and synthesis of tricyclic sulfones as g-secretase inhibitors with greatly reduced Notch toxicityXu, R. / Cole, D. / Asberom, T. / Bara, T. / Bennett, C. / Burnett, D. A. / Clader, J. / Domalski, M. / Greenlee, W. / Hyde, L. et al. | 2010
- 2597
-
Substituted hydrazinecarbothioamide as potent antitubercular agents: Synthesis and quantitative structure–activity relationship (QSAR)Singh, Supriya / Mandal, Pintu K. / Singh, Nagendra / Misra, Anup K. / Singh, Shubhra / Chaturvedi, Vinita / Sinha, Sudhir / Saxena, Anil K. et al. | 2010
- 2601
-
(−)-Carbodine: Enantiomeric synthesis and in vitro antiviral activity against various strains of influenza virus including H5N1 (avian influenza) and novel 2009 H1N1 (swine flu)Rao, Jagadeeshwar R. / Jha, Ashok K. / Rawal, Ravindra K. / Sharon, Ashoke / Day, Craig W. / Barnard, Dale L. / Smee, Donald F. / Chu, Chung K. et al. | 2010
- 2605
-
(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl)propanoic acid compounds: Synthesis and biological evaluation of dual PPARa/g agonistsZhou, X. / Chen, W. / Xu, C. / Fan, S. / Xie, Y. / Zhong, W. / Wang, L. / Li, S. et al. | 2010
- 2605
-
(S)-3-(4-(2-(5-Methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)-2-(piperazin-1-yl)propanoic acid compounds: Synthesis and biological evaluation of dual PPARα/γ agonistsZhou, Xinbo / Chen, Wei / Xu, Cheng / Fan, Shiyong / Xie, Yunde / Zhong, Wu / Wang, Lili / Li, Song et al. | 2010
- 2609
-
Discovery and SAR of potent, orally available 2,8-diaryl-quinoxalines as a new class of JAK2 inhibitorsPissot-Soldermann, Carole / Gerspacher, Marc / Furet, Pascal / Gaul, Christoph / Holzer, Philipp / McCarthy, Clive / Radimerski, Thomas / Regnier, Catherine H. / Baffert, Fabienne / Drueckes, Peter et al. | 2010
- 2614
-
Design, synthesis and in vitro/in vivo evaluation of orally bioavailable prodrugs of a catechol-O-methyltransferase inhibitorRautio, Jarkko / Leppänen, Jukka / Lehtonen, Marko / Laine, Krista / Koskinen, Mikko / Pystynen, Jarmo / Savolainen, Jouko / Sairanen, Mikko et al. | 2010
- 2617
-
The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitorBennett, Frank / Huang, Yuhua / Hendrata, Siska / Lovey, Raymond / Bogen, Stephane L. / Pan, Weidong / Guo, Zhuyan / Prongay, Andrew / Chen, Kevin X. / Arasappan, Ashok et al. | 2010
- 2622
-
4,7-Dichloro benzothien-2-yl sulfonylaminomethyl boronic acid: First boronic acid-derived beta-lactamase inhibitor with class A, C, and D activityTan, Qiang / Ogawa, Aimie M. / Painter, Ronald E. / Park, Young-Whan / Young, Katherine / DiNinno, Frank P. et al. | 2010
- 2625
-
Synthesis and bioluminescence-inducing properties of autoinducer (S)-4,5-dihydroxypentane-2,3-dione and its enantiomerKadirvel, Manikandan / Stimpson, William T. / Moumene-Afifi, Souad / Arsic, Biljana / Glynn, Nicola / Halliday, Nigel / Williams, Paul / Gilbert, Peter / McBain, Andrew J. / Freeman, Sally et al. | 2010
- 2629
-
Selectivity profiling of novel indene H1-antihistamines for the treatment of insomniaLi, Bin-Feng / Moree, Wilna J. / Yu, Jinghua / Coon, Timothy / Zamani-Kord, Said / Malany, Siobhan / Jalali, Kayvon / Wen, Jianyun / Wang, Hua / Yang, Chun et al. | 2010
- 2634
-
Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinaseWalker, John K. / Selness, Shaun R. / Devraj, Rajesh V. / Hepperle, Michael E. / Naing, Win / Shieh, Huey / Kurambail, Ravi / Yang, Syaulan / Flynn, Daniel L. / Benson, Alan G. et al. | 2010
- 2639
-
Discovery of novel N-acylsulfonamide analogs as potent and selective EP3 receptor antagonistsAsada, Masaki / Obitsu, Tetsuo / Kinoshita, Atsushi / Nakai, Yoshihiko / Nagase, Toshihiko / Sugimoto, Isamu / Tanaka, Motoyuki / Takizawa, Hiroya / Yoshikawa, Ken / Sato, Kazutoyo et al. | 2010
- 2644
-
Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitorsZask, Arie / Verheijen, Jeroen C. / Richard, David J. / Kaplan, Joshua / Curran, Kevin / Toral-Barza, Lourdes / Lucas, Judy / Hollander, Irwin / Yu, Ker et al. | 2010
- 2648
-
2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: Optimization of human microsomal stabilityVerheijen, Jeroen C. / Richard, David J. / Curran, Kevin / Kaplan, Joshua / Yu, Ker / Zask, Arie et al. | 2010
- 2654
-
Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3KαRichard, David J. / Verheijen, Jeroen C. / Yu, Ker / Zask, Arie et al. | 2010
- 2654
-
Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3KaRichard, D. J. / Verheijen, J. C. / Yu, K. / Zask, A. et al. | 2010
- 2658
-
1,7-Disubstituted oxyindoles are potent and selective EP3 receptor antagonistsZhou, Nian / Polozov, Alexandre M. / O’Connell, Matthew / Burgeson, James / Yu, Peng / Zeller, Wayne / Zhang, Jun / Onua, Emmanuel / Ramirez, Jose / Palsdottir, Gudrun A. et al. | 2010
- 2665
-
Endoxifen is a new potent inhibitor of PKC: A potential therapeutic agent for bipolar disorderAli, Shoukath M. / Ahmad, Ateeq / Shahabuddin, Syed / Ahmad, Moghis U. / Sheikh, Saifuddin / Ahmad, Imran et al. | 2010
- 2668
-
A new cytotoxic tambjamine alkaloid from the Azorean nudibranch Tambja ceutaeCarbone, Marianna / Irace, Carlo / Costagliola, Francesca / Castelluccio, Francesco / Villani, Guido / Calado, Gonçalo / Padula, Vinicius / Cimino, Guido / Lucas Cervera, J. / Santamaria, Rita et al. | 2010
- 2671
-
Synthesis and antibacterial activity of new 9-O-arylpropenyloxime ketolidesNam, Ghilsoo / Kim, Yang Soo / Choi, Kyung Il et al. | 2010
- 2675
-
Enhanced Nrf2-dependent induction of glutathione in mouse embryonic fibroblasts by isoselenocyanate analog of sulforaphaneEmmert, Sans W. / Desai, Dhimant / Amin, Shantu / Richie, John P. Jr. et al. | 2010
- 2680
-
Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system over the vesicular glutamate transporterEtoga, Jean-Louis G. / Ahmed, S. Kaleem / Patel, Sarjubhai / Bridges, Richard J. / Thompson, Charles M. et al. | 2009
- 2680
-
Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system over the vesicular glutamate transporterEtoga, Jean-Louis G. et al. | 2010
- 2680
-
Conformationally-restricted amino acid analogues bearing a distal sulfonic acid show selective inhibition of system Formula Not Shown over the vesicular glutamate transporterEtoga, J. L. / Ahmed, S. K. / Patel, S. / Bridges, R. J. / Thompson, C. M. et al. | 2010
- 2684
-
Corrigendum to “A novel chemotype of kinase inhibitors: Discovery of 3,4-ring fused 7-azaindoles and deazapurines as potent JAK2 inhibitors” [Bioorg. Med. Chem. Lett. 20 (2010) 153]Wang, Tiansheng / Ledeboer, Mark W. / Duffy, John P. / Salituro, Francesco G. / Pierce, Albert C. / Zuccola, Harmon J. / Block, Eric / Shlyakter, Dina / Hogan, James K. / Bennani, Youssef L. et al. | 2010
- 2685
-
Corrigendum to “Quinazolin-4-piperidin-4-methyl sulfamide PC-1 inhibitors: Alleviating hERG interactions through structure based design” [Bioorg. Med. Chem. Lett. 19 (2009) 3339]Patel, Snahel D. / Habeski, Wendy M. / Cheng, Alan C. / Cruz, Elisa de la / Loh, Christine / Kablaoui, Natasha M. et al. | 2010
- IFC
-
Editorial board| 2010