(−)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels (English)
- New search for: Ortar, Giorgio
- New search for: Ortar, Giorgio
- New search for: Petrocellis, Luciano De
- New search for: Morera, Ludovica
- New search for: Moriello, Aniello Schiano
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- New search for: Nalli, Marianna
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In:
Bioorganic & medicinal chemistry letters
;
20
, 9
; 2729-2733
;
2010
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ISSN:
- Article (Journal) / Print
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Title:(−)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels
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Contributors:
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Published in:Bioorganic & medicinal chemistry letters ; 20, 9 ; 2729-2733
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Publisher:
- New search for: Elsevier
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Place of publication:Amsterdam [u.a.]
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Publication date:2010
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ISSN:
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ZDBID:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 44.33 / 44.42
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Source:
Table of contents – Volume 20, Issue 9
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 2687
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Graphical contents list| 2010
- 2705
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Synthesis and biological evaluation of 1,4-diazepane derivatives as T-type calcium channel blockersGu, Su Jin / Lee, Jae Kyun / Pae, Ae Nim / Chung, Hye Jin / Rhim, Hyewon / Han, So Yeob / Min, Sun-Joon / Cho, Yong Seo et al. | 2010
- 2709
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Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and BAlcaro, Stefano / Gaspar, Alexandra / Ortuso, Francesco / Milhazes, Nuno / Orallo, Francisco / Uriarte, Eugenio / Yáñez, Matilde / Borges, Fernanda et al. | 2010
- 2713
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Click reaction synthesis of carbohydrate derivatives from ristocetin aglycon with antibacterial and antiviral activityPintér, Gábor / Bereczki, Ilona / Batta, Gyula / Ötvös, Réka / Sztaricskai, Ferenc / Rőth, Erzsébet / Ostorházi, Eszter / Rozgonyi, Ferenc / Naesens, Lieve / Szarvas, Mariann et al. | 2010
- 2718
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Gold nanoparticles capped with sulfate-ended ligands as anti-HIV agentsDi Gianvincenzo, Paolo / Marradi, Marco / Martínez-Ávila, Olga María / Bedoya, Luis Miguel / Alcamí, José / Penadés, Soledad et al. | 2010
- 2722
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Synthesis and evaluation of a series of C5prime-substituted duocarmycin SA analogsRobertson, W. M. / Kastrinsky, D. B. / Hwang, I. / Boger, D. L. et al. | 2010
- 2722
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Synthesis and evaluation of a series of C5′-substituted duocarmycin SA analogsRobertson, William M. / Kastrinsky, David B. / Hwang, Inkyu / Boger, Dale L. et al. | 2010
- 2726
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Transkarbams as transdermal permeation enhancers: Effects of ester position and ammonium carbamate formationNovotný, Michal / Hrabálek, Alexandr / Janůšová, Barbora / Novotný, Jakub / Vávrová, Kateřina et al. | 2010
- 2729
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(−)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channelsOrtar, Giorgio / Petrocellis, Luciano De / Morera, Ludovica / Moriello, Aniello Schiano / Orlando, Pierangelo / Morera, Enrico / Nalli, Marianna / Marzo, Vincenzo Di et al. | 2010
- 2733
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Symmetrical α-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluationRomagnoli, Romeo / Baraldi, Pier Giovanni / Cruz-Lopez, Olga / Cara, Carlota Lopez / Carrion, Maria Dora / Balzarini, Jan / Hamel, Ernest / Basso, Giuseppe / Bortolozzi, Roberta / Viola, Giampietro et al. | 2010
- 2733
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Symmetrical a-bromoacryloylamido diaryldienone derivatives as a novel series of antiproliferative agents. Design, synthesis and biological evaluationRomagnoli, R. / Baraldi, P. G. / Cruz-Lopez, O. / Cara, C. L. / Carrion, M. D. / Balzarini, J. / Hamel, E. / Basso, G. / Bortolozzi, R. / Viola, G. et al. | 2010
- 2740
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Exploration of secondary and tertiary pharmacophores in unsymmetrical N,N′-diaryl urea inhibitors of soluble epoxide hydrolaseAnandan, Sampath-Kumar / Gless, Richard D. et al. | 2010
- 2740
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Exploration of secondary and tertiary pharmacophores in unsymmetrical N,Nprime-diaryl urea inhibitors of soluble epoxide hydrolaseAnandan, S. K. / Gless, R. D. et al. | 2010
- 2745
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Identification of a novel series of potent RON receptor tyrosine kinase inhibitorsRaeppel, Stéphane / Gaudette, Frédéric / Mannion, Michael / Claridge, Stephen / Saavedra, Oscar / Isakovic, Ljubomir / Déziel, Robert / Beaulieu, Normand / Beaulieu, Carole / Dupont, Isabelle et al. | 2010
- 2750
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Synthesis and biological evaluation of modified pentapeptides as potent proteinase K inhibitorsKore, Anilkumar R. / Shanmugasundaram, Muthian / Charles, Irudaya / Hoang, Quoc et al. | 2010
- 2755
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Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonistsStocking, Emily M. / Aluisio, Leah / Atack, John R. / Bonaventure, Pascal / Carruthers, Nicholas I. / Dugovic, Christine / Everson, Anita / Fraser, Ian / Jiang, Xiaohui / Leung, Perry et al. | 2010
- 2761
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Squalenoyl nucleoside monophosphate nanoassemblies: New prodrug strategy for the delivery of nucleotide analoguesCaron, Joachim / Reddy, L. Harivardhan / Lepêtre-Mouelhi, Sinda / Wack, Séverine / Clayette, Pascal / Rogez-Kreuz, Christine / Yousfi, Rahima / Couvreur, Patrick / Desmaële, Didier et al. | 2010
- 2765
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Synthesis and biological activity of 2H-quinolizin-2-one based p38α MAP kinase inhibitorsTynebor, Robert M. / Chen, Meng-Hsin / Natarajan, Swaminathan R. / O’Neill, Edward A. / Thompson, James E. / Fitzgerald, Catherine E. / O’Keefe, Stephen J. / Doherty, James B. et al. | 2010
- 2765
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Synthesis and biological activity of 2H-quinolizin-2-one based p38a MAP kinase inhibitorsTynebor, R. M. / Chen, M. H. / Natarajan, S. R. / O'Neill, E. A. / Thompson, J. E. / Fitzgerald, C. E. / O'Keefe, S. J. / Doherty, J. B. et al. | 2010
- 2770
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Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution patternLange, Jos H.M. / van der Neut, Martina A.W. / Borst, Alice J.M. / Yildirim, Mahmut / van Stuivenberg, Herman H. / van Vliet, Bernard J. / Kruse, Chris G. et al. | 2010
- 2776
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Expression and characterization of Mycobacterium tuberculosis methionine aminopeptidase type 1aLu, Jing-Ping / Ye, Qi-Zhuang et al. | 2010
- 2780
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Synthesis and biological evaluation of combretastatin analogs as cell cycle inhibitors of the G1 to S transition in Saccharomyces cerevisiaeCoccetti, Paola / Montano, Giuseppe / Lombardo, Alessandro / Tripodi, Farida / Orsini, Fulvia / Pagliarin, Roberto et al. | 2010
- 2785
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Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonistsGuo, Cheng / Guzzo, Peter R. / Hadden, Mark / Sargent, Bruce J. / Yet, Larry / Kan, Yanqing / Palyha, Oksana / Kelly, Theresa M. / Guan, Xiaoming / Rosko, Kim et al. | 2010
- 2790
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Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosidesWang, Ping / Ownby, Stacy / Zhang, Zhizhen / Yuan, Wei / Li, Shiyou et al. | 2010
- 2797
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Potent tricyclic pyrazole tetrazole agonists of the nicotinic acid receptor (GPR109a)Boatman, P. Douglas / Schrader, Thomas O. / Kasem, Michelle / Johnson, Benjamin R. / Skinner, Philip J. / Jung, Jae-Kyu / Xu, Jerry / Cherrier, Martin C. / Webb, Peter J. / Semple, Graeme et al. | 2010
- 2801
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Identification and structure–activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinaseSliman, Faten / Blairvacq, Mélina / Durieu, Emilie / Meijer, Laurent / Rodrigo, Jordi / Desmaële, Didier et al. | 2010
- 2806
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2-C-Methyluridine modified hammerhead ribozyme against the estrogen receptorPontiggia, Rodrigo / Pontiggia, Osvaldo / Simian, Marina / Montserrat, Javier M. / Engels, Joachim W. / Iribarren, Adolfo M. et al. | 2010
- 2809
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Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitorsSabatucci, Joseph P. / Mahaney, Paige E. / Leiter, Jennifer / Johnston, Grace / Burroughs, Kevin / Cosmi, Scott / Zhang, Yingru / Ho, Douglas / Deecher, Darlene C. / Trybulski, Eugene et al. | 2010
- 2813
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A rapid oxime linker-based library approach to identification of bivalent inhibitors of the Yersinia pestis protein-tyrosine phosphatase, YopHLiu, Fa / Hakami, Ramin Mollaaghababa / Dyas, Beverly / Bahta, Medhanit / Lountos, George T. / Waugh, David S. / Ulrich, Robert G. / Burke, Terrence R. Jr. et al. | 2010
- 2817
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Design of environmentally sensitive fluorescent 2′-deoxyguanosine containing arylethynyl moieties: Distinction of thymine base by base-discriminating fluorescent (BDF) probeShinohara, Yuta / Matsumoto, Katsuhiko / Kugenuma, Kenji / Morii, Takashi / Saito, Yoshio / Saito, Isao et al. | 2010
- 2817
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Design of environmentally sensitive fluorescent 2prime-deoxyguanosine containing arylethynyl moieties: Distinction of thymine base by base-discriminating fluorescent (BDF) probeShinohara, Y. / Matsumoto, K. / Kugenuma, K. / Morii, T. / Saito, Y. / Saito, I. et al. | 2010
- 2821
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Cytotoxicity against KB and NCI-H187 cell lines of modified flavonoids from Kaempferia parvifloraYenjai, Chavi / Wanich, Suchana et al. | 2010
- 2824
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Inhibition of antigen-induced degranulation by aryl compounds isolated from the bark of Betula platyphylla in RBL-2H3 cellsKim, Seung Hyun / Park, Jung Hyun / Kim, Tae Bum / Lee, Hyang Hwa / Lee, Ki Yong / Kim, Young Choong / Sung, Sang Hyun et al. | 2010
- 2828
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Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyraseRonkin, Steven M. / Badia, Michael / Bellon, Steve / Grillot, Anne-Laure / Gross, Christian H. / Grossman, Trudy H. / Mani, Nagraj / Parsons, Jonathan D. / Stamos, Dean / Trudeau, Martin et al. | 2010
- 2832
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Imidazoacridin-6-ones as novel inhibitors of the quinone oxidoreductase NQO2Nolan, K.A. / Humphries, M.P. / Bryce, R.A. / Stratford, I.J. et al. | 2010
- 2837
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Piperazine sulfonamide BACE1 inhibitors: Design, synthesis, and in vivo characterizationCumming, Jared / Babu, Suresh / Huang, Ying / Carrol, Carolyn / Chen, Xia / Favreau, Leonard / Greenlee, William / Guo, Tao / Kennedy, Matthew / Kuvelkar, Reshma et al. | 2010
- 2843
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The cytotoxic styryl lactone goniothalamin is an inhibitor of nucleocytoplasmic transportWach, Jean-Yves / Güttinger, Stephan / Kutay, Ulrike / Gademann, Karl et al. | 2010
- 2847
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New diterpenoids from Caesalpinia species and their cytotoxic activityDas, Biswanath / Srinivas, Yallamalla / Sudhakar, Chithaluri / Mahender, Ibram / Laxminarayana, Keetha / Reddy, Parigi Raghavendar / Raju, Tuniki Venugopal / Jakka, Naga Mahesh / Rao, Janapala Venkateswara et al. | 2010
- 2851
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Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffoldsSandanayaka, Vincent / Mamat, Bjorn / Bhagat, Nikhil / Bedell, Louis / Halldorsdottir, Gudrun / Sigthorsdottir, Heida / Andrésson, Þorkell / Kiselyov, Alex / Gurney, Mark / Singh, Jasbir et al. | 2010
- 2855
-
Synthesis and anti-tumor activities of methyl 2-O-aryl-6-O-arylprime-d-glucopyranosidesShi, H. / Zhou, B. / Li, W. / Shi, Z. / Yu, B. / Wang, R. et al. | 2010
- 2855
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Synthesis and anti-tumor activities of methyl 2-O-aryl-6-O-aryl′-d-glucopyranosidesShi, Hefang / Zhou, Bingcheng / Li, Wenwen / Shi, Zhimin / Yu, Biao / Wang, Renxiao et al. | 2010
- 2859
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4-Substituted 4-(1H-1,2,3-triazol-1-yl)piperidine: Novel C7 moieties of fluoroquinolones as antibacterial agentsHuang, Xiaoguang / Zhang, Aiqin / Chen, Dongliang / Jia, Zhenhua / Li, Xingshu et al. | 2010
- 2864
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Methylene amine substituted arylindenopyrimidines as potent adenosine A2A/A1 antagonistsShook, Brian C. / Rassnick, Stefanie / Hall, Daniel / Rupert, Kenneth C. / Heintzelman, Geoffrey R. / Hansen, Kristen / Chakravarty, Devraj / Bullington, James L. / Scannevin, Robert H. / Magliaro, Brian et al. | 2010
- 2868
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Optimization of arylindenopyrimidines as potent adenosine A2A/A1 antagonistsShook, Brian C. / Rassnick, Stefanie / Chakravarty, Devraj / Wallace, Nathaniel / Ault, Mark / Crooke, Jeffrey / Barbay, J. Kent / Wang, Aihua / Leonard, Kristi / Powell, Mark T. et al. | 2010
- 2872
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Chlorin e6–cholesterol conjugate and its copper complex. Simple synthesis and entrapping in phospholipid vesiclesNikolaeva, Irina A. / Misharin, Alexander Yu. / Ponomarev, Gelii V. / Timofeev, Vladimir P. / Tkachev, Yaroslav V. et al. | 2010
- 2876
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Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25BChen, Hai-Jun / Liu, Yong / Wang, Li-Na / Shen, Qiang / Li, Jia / Nan, Fa-Jun et al. | 2010
- 2880
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Synthesis and antibacterial activities of a novel alkylide: 3-O-(3-aryl-2-propargyl) and 3-O-(3-aryl-2-propenyl)clarithromycin derivativesLiang, Jian-Hua / Wang, Yue-Ying / Wang, He / Li, Xiao-Li / An, Kun / Xu, Ying-Chun / Yao, Guo-Wei et al. | 2010
- 2884
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Design and an efficient synthesis of new thiorotenone derivativesYao, Changsheng / Wang, Cuihua / Jiang, Bei / Feng, Xiaodong / Yu, Chenxia / Li, Tuanjie / Tu, Shujiang et al. | 2010
- 2888
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Design of new dopamine D2 receptor ligands: Biosynthesis and pharmacological evaluation of the hydroxylated metabolite of LASSBio-581Pazini, Francine / Menegatti, Ricardo / Sabino, José R. / Andrade, Carolina H. / Neves, Gilda / Rates, Stela M.K. / Noël, François / Fraga, Carlos A.M. / Barreiro, Eliezer J. / de Oliveira, Valéria et al. | 2010
- 2892
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Identification of benzimidazole-based inhibitors of the mitogen activated kinase-5 signaling pathwayFlaherty, Patrick T. / Chopra, Ishveen / Jain, Prashi / Yi, Shuyan / Allen, Erika / Cavanaugh, Jane et al. | 2010
- 2897
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The development and SAR of pyrrolidine carboxamide 11β-HSD1 inhibitorsCheng, Hengmiao / Hoffman, Jacqui / Le, Phuong / Nair, Sajiv K. / Cripps, Stephan / Matthews, Jean / Smith, Christopher / Yang, Michele / Kupchinsky, Stan / Dress, Klaus et al. | 2010
- 2897
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The development and SAR of pyrrolidine carboxamide 11b-HSD1 inhibitorsCheng, H. / Hoffman, J. / Le, P. / Nair, S. K. / Cripps, S. / Matthews, J. / Smith, C. / Yang, M. / Kupchinsky, S. / Dress, K. et al. | 2010
- 2903
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Synthesis of 4-(3-biaryl)quinoline sulfones as potent liver X receptor agonistsUllrich, John W. / Morris, Robert / Bernotas, Ronald C. / Travins, Jeremy M. / Jetter, James / Unwalla, Rayomand / Quinet, Elaine / Nambi, Ponnal / Feingold, Irene / Huselton, Christine et al. | 2010
- 2908
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Selective targeting of 2prime-deoxy-5-fluorouridine to urokinase positive malignant cells in vitroVine, K. L. / Locke, J. M. / Bremner, J. B. / Pyne, S. G. / Ranson, M. et al. | 2010
- 2908
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Selective targeting of 2′-deoxy-5-fluorouridine to urokinase positive malignant cells in vitroVine, Kara L. / Locke, Julie M. / Bremner, John B. / Pyne, Stephen G. / Ranson, Marie et al. | 2010
- 2912
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Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesityHadden, Mark / Goodman, Allan / Guo, Cheng / Guzzo, Peter R. / Henderson, Alan J. / Pattamana, Kevin / Ruenz, Megan / Sargent, Bruce J. / Swenson, Brian / Yet, Larry et al. | 2010
- 2916
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The discovery and structure–activity relationships of 2-(piperidin-3-yl)-1H-benzimidazoles as selective, CNS penetrating H1-antihistamines for insomniaLavrador-Erb, Karine / Ravula, Satheesh Babu / Yu, Jinghua / Zamani-Kord, Said / Moree, Wilna J. / Petroski, Robert E. / Wen, Jianyun / Malany, Siobhan / Hoare, Samuel R.J. / Madan, Ajay et al. | 2010
- 2920
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Truxillic acid derivatives act as peroxisome proliferator-activated receptor γ activatorsSteri, Ramona / Rupp, Matthias / Proschak, Ewgenij / Schroeter, Timon / Zettl, Heiko / Hansen, Katja / Schwarz, Oliver / Müller-Kuhrt, Lutz / Müller, Klaus-Robert / Schneider, Gisbert et al. | 2010
- 2920
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Truxillic acid derivatives act as peroxisome proliferator-activated receptor g activatorsSteri, R. / Rupp, M. / Proschak, E. / Schroeter, T. / Zettl, H. / Hansen, K. / Schwarz, O. / Muller-Kuhrt, L. / Muller, K. R. / Schneider, G. et al. | 2010
- 2924
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Optimization of 7-alkene-3-quinolinecarbonitriles as Src kinase inhibitorsBoschelli, Diane H. / Wang, Daniel / Wang, Yan / Wu, Biqi / Honores, Erick E. / Barrios Sosa, Ana Carolina / Chaudhary, Inder / Golas, Jennifer / Lucas, Judy / Boschelli, Frank et al. | 2010
- 2928
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Water-soluble PDE4 inhibitors for the treatment of dry eyeGovek, Steven P. / Oshiro, Guy / Anzola, John V. / Beauregard, Clay / Chen, Jasmine / Coyle, Avery R. / Gamache, Daniel A. / Hellberg, Mark R. / Hsien, Jennifer N. / Lerch, Julia M. et al. | 2010
- 2933
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Synthesis and structure-activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARa selective activators- PPARa and PPARg selectivity modulationYe, X. Y. / Chen, S. / Zhang, H. / Locke, K. T. / O'Malley, K. / Zhang, L. / Srivastava, R. / Miao, B. / Meyers, D. / Monshizadegan, H. et al. | 2010
- 2933
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Synthesis and structure–activity relationships of 2-aryl-4-oxazolylmethoxy benzylglycines and 2-aryl-4-thiazolylmethoxy benzylglycines as novel, potent PPARα selective activators- PPARα and PPARγ selectivity modulationYe, Xiang-Yang / Chen, Stephanie / Zhang, Hao / Locke, Kenneth T. / O’Malley, Kevin / Zhang, Litao / Srivastava, Raijit / Miao, Bowman / Meyers, Daniel / Monshizadegan, Hossain et al. | 2010
- 2938
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A prodrug approach towards the development of tricyclic-based FBPase inhibitorsTsukada, Tomoharu / Tamaki, Kazuhiko / Tanaka, Jun / Takagi, Toshiyuki / Yoshida, Taishi / Okuno, Akira / Shiiki, Takeshi / Takahashi, Mizuki / Nishi, Takahide et al. | 2010
- 2942
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Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivativesXu, Yulan / Sheng, Chunquan / Wang, Wenya / Che, Xiaoying / Cao, Yongbing / Dong, Guoqiang / Wang, Shengzheng / Ji, Haitao / Miao, Zhenyuan / Yao, Jianzhong et al. | 2010
- 2946
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Bivalent 5,8,9,13b-tetrahydro-6H-isoquino[1,2-a]isoquinolines and -isoquinolinium salts: Novel heterocyclic templates for butyrylcholinesterase inhibitorsSchulze, Maria / Siol, Oliver / Decker, Michael / Lehmann, Jochen et al. | 2010
- 2950
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Molecular modelling, synthesis and acetylcholinesterase inhibition of ethyl 5-amino-2-methyl-6,7,8,9-tetrahydrobenzo[b][1,8]naphthyridine-3-carboxylateSoriano, Elena / Samadi, Abdelouahid / Chioua, Mourad / Ríos, Cristóbal de los / Marco-Contelles, José et al. | 2010
- 2954
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A 3D-pharmacophore model for σ2 receptors based on a series of substituted benzo[d]oxazol-2(3H)-one derivativesLaurini, Erik / Zampieri, Daniele / Mamolo, Maria Grazia / Vio, Luciano / Zanette, Caterina / Florio, Chiara / Posocco, Paola / Fermeglia, Maurizio / Pricl, Sabrina et al. | 2010
- 2958
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Inhibition of g-secretase by the CK1 inhibitor IC261 does not depend on CK1dHottecke, N. / Liebeck, M. / Baumann, K. / Schubenel, R. / Winkler, E. / Steiner, H. / Schmidt, B. et al. | 2010
- 2958
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Inhibition of γ-secretase by the CK1 inhibitor IC261 does not depend on CK1δHöttecke, Nicole / Liebeck, Miriam / Baumann, Karlheinz / Schubenel, Robert / Winkler, Edith / Steiner, Harald / Schmidt, Boris et al. | 2010
- 2964
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In vitro selection of a photoresponsive RNA aptamer to heminLiu, Mingzhe / Jinmei, Hiroshi / Abe, Hiroshi / Ito, Yoshihiro et al. | 2010
- 2968
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The discovery and structure–activity relationships of pyrano[3,4-b]indole based inhibitors of hepatitis C virus NS5B polymeraseLaPorte, Matthew G. / Draper, Tandy L. / Miller, Lori E. / Blackledge, Charles W. / Leister, Lara K. / Amparo, Eugene / Hussey, Alison R. / Young, Dorothy C. / Chunduru, Srinivas K. / Benetatos, Christopher A. et al. | 2010
- 2974
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Bioactivity-guided isolation of mosquitocidal constituents from the rhizomes of Plumbago capensis ThunbSreelatha, T. / Hymavathi, A. / Murthy, J. Madhusudhana / Rani, P.U. / Rao, J. Madhusudana / Babu, K. Suresh et al. | 2010
- 2978
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New 5-HT1A receptor ligands containing a Nprime-cyanoisonicotinamidine nucleus: Synthesis and in vitro pharmacological evaluationFiorino, F. / Severino, B. / De Angelis, F. / Perissutti, E. / Magli, E. / Frecentese, F. / Esposito, A. / Massarelli, P. / Nencini, C. / Santagada, V. et al. | 2010
- 2978
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New 5-HT1A receptor ligands containing a N′-cyanoisonicotinamidine nucleus: Synthesis and in vitro pharmacological evaluationFiorino, Ferdinando / Severino, Beatrice / De Angelis, Francesca / Perissutti, Elisa / Magli, Elisa / Frecentese, Francesco / Esposito, Antonella / Massarelli, Paola / Nencini, Cristina / Santagada, Vincenzo et al. | 2010
- 2983
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Potent dihydroquinolinone dopamine D2 partial agonist/serotonin reuptake inhibitors for the treatment of schizophreniaYan, Yinfa / Zhou, Ping / Rotella, David P. / Feenstra, Rolf / Kruse, Chris G. / Reinders, Jan-Hendrik / Neut, Martina van der / Lai, Margaret / Zhang, Jean / Kowal, Dianne M. et al. | 2010
- 2987
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Peripheral site acetylcholinesterase inhibitors targeting both inflammation and cholinergic dysfunctionYoung, Sherri / Fabio, Karine / Guillon, Christophe / Mohanta, Pramod / Halton, Timothy A. / Heck, Diane E. / Flowers, Robert A. II / Laskin, Jeffrey D. / Heindel, Ned D. et al. | 2010
- 2991
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Structural requirement(s) of N-phenylthioureas and benzaldehyde thiosemicarbazones as inhibitors of melanogenesis in melanoma B 16 cellsThanigaimalai, P. / Le Hoang, Tuan Anh / Lee, Ki-Cheul / Bang, Seong-Cheol / Sharma, Vinay K. / Yun, Cheong-Yong / Roh, Eunmiri / Hwang, Bang-Yeon / Kim, Youngsoo / Jung, Sang-Hun et al. | 2010
- 2994
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Cucurbitacin E as a new inhibitor of cofilin phosphorylation in human leukemia U937 cellsNakashima, Souichi / Matsuda, Hisashi / Kurume, Ai / Oda, Yoshimi / Nakamura, Seikou / Yamashita, Masayuki / Yoshikawa, Masayuki et al. | 2010
- 2998
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Design, synthesis and structure–activity relationships of novel biarylamine-based Met kinase inhibitorsWilliams, David K. / Chen, Xiao-Tao / Tarby, Christine / Kaltenbach, Robert / Cai, Zhen-Wei / Tokarski, John S. / An, Yongmi / Sack, John S. / Wautlet, Barri / Gullo-Brown, Johnni et al. | 2010
- 3003
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Synthesis and biological evaluation of novel 2-arylalkylthio-4-amino-6-benzyl pyrimidines as potent HIV-1 non-nucleoside reverse transcriptase inhibitorsQin, Hua / Liu, Chang / Zhang, Jianfang / Guo, Ying / Zhang, Siwei / Zhang, Zhili / Wang, Xiaowei / Zhang, Liangren / Liu, Junyi et al. | 2009
- IFC
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Editorial board| 2010