Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin (English)
- New search for: Roubalová, Lenka
- New search for: Roubalová, Lenka
- New search for: Purchartová, Kateřina
- New search for: Papoušková, Barbora
- New search for: Vacek, Jan
- New search for: Křen, Vladimír
- New search for: Ulrichová, Jitka
- New search for: Vrba, Jiří
In:
Bioorganic & medicinal chemistry
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23
, 17
; 5402-5409
;
2015
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ISSN:
- Article (Journal) / Print
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Title:Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolin
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Contributors:Roubalová, Lenka ( author ) / Purchartová, Kateřina / Papoušková, Barbora / Vacek, Jan / Křen, Vladimír / Ulrichová, Jitka / Vrba, Jiří
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Published in:Bioorganic & medicinal chemistry ; 23, 17 ; 5402-5409
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Publisher:
- New search for: Elsevier
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Place of publication:Amsterdam [u.a.]
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Publication date:2015
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ISSN:
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ZDBID:
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DOI:
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Type of media:Article (Journal)
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Type of material:Print
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Language:English
- New search for: 35.70 / 44.33 / 44.40
- Further information on Basic classification
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Source:
Table of contents – Volume 23, Issue 17
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 5225
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Graphical contents list| 2015
- 5247
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Pyrroloaryls and pyrroloheteroaryls: Inhibitors of the HIV fusion/attachment, reverse transcriptase and integrasePatel, Rahul V. / Park, Se Won et al. | 2015
- 5264
-
Synthesis and evaluation of arylpiperazine-reverse amides as biased dopamine D3 receptor ligandsCao, Yongkai / Paudel, Suresh / Zhang, Xiaowei / Kim, Kyeong-Man / Cheon, Seung Hoon et al. | 2015
- 5273
-
Synthesis, biological evaluation and docking study of maleimide derivatives bearing benzenesulfonamide as selective COX-2 inhibitors and anti-inflammatory agentsFirke, Sandip D. / Bari, Sanjay B. et al. | 2015
- 5282
-
1,5-Disubstituted benzimidazoles that direct cardiomyocyte differentiation from mouse embryonic stem cellsOkolotowicz, Karl J. / Bushway, Paul / Lanier, Marion / Gilley, Cynthia / Mercola, Mark / Cashman, John R. et al. | 2015
- 5293
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Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent RORγt inverse agonistsWang, Yonghui / Yang, Ting / Liu, Qian / Ma, Yingli / Yang, Liuqing / Zhou, Ling / Xiang, Zhijun / Cheng, Ziqiang / Lu, Sijie / Orband-Miller, Lisa A. et al. | 2015
- 5303
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A new small molecule inhibitor of soluble guanylate cyclaseMota, Filipa / Gane, Paul / Hampden-Smith, Kathryn / Allerston, Charles K. / Garthwaite, John / Selwood, David L. et al. | 2015
- 5311
-
Exploring new Probenecid-based carbonic anhydrase inhibitors: Synthesis, biological evaluation and docking studiesMollica, Adriano / Costante, Roberto / Akdemir, Atilla / Carradori, Simone / Stefanucci, Azzurra / Macedonio, Giorgia / Ceruso, Mariangela / Supuran, Claudiu T. et al. | 2015
- 5319
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Photoaffinity labeling studies of the carbohydrate-binding proteins with different affinitiesSakurai, Kaori / Ozawa, Shimpei / Yamaguchi, Tamayo et al. | 2015
- 5326
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Tight binding enantiomers of pre-clinical drug candidatesEvans, Gary B. / Cameron, Scott A. / Luxenburger, Andreas / Guan, Rong / Suarez, Javier / Thomas, Keisha / Schramm, Vern L. / Tyler, Peter C. et al. | 2015
- 5334
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Ribosome-targeting antibiotics as inhibitors of oncogenic microRNAs biogenesis: Old scaffolds for new perspectives in RNA targetingTran, Thi Phuong Anh / Vo, Duc Duy / Di Giorgio, Audrey / Duca, Maria et al. | 2015
- 5345
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Carbon nanotubes supported tyrosinase in the synthesis of lipophilic hydroxytyrosol and dihydrocaffeoyl catechols with antiviral activity against DNA and RNA virusesBotta, Giorgia / Bizzarri, Bruno Mattia / Garozzo, Adriana / Timpanaro, Rossella / Bisignano, Benedetta / Amatore, Donatella / Palamara, Anna Teresa / Nencioni, Lucia / Saladino, Raffaele et al. | 2015
- 5352
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Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacyLounsbury, Nicole / Mateo, George / Jones, Brielle / Papaiahgari, Srinivas / Thimmulappa, Rajash K. / Teijaro, Christiana / Gordon, John / Korzekwa, Kenneth / Ye, Min / Allaway, Graham et al. | 2015
- 5360
-
Synthesis, binding, nuclease resistance and cellular uptake properties of 2′-O-acetalester-modified oligonucleotides containing cationic groupsBiscans, Annabelle / Rouanet, Sonia / Bertrand, Jean-Rémi / Vasseur, Jean-Jacques / Dupouy, Christelle / Debart, Françoise et al. | 2015
- 5369
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Phosphate-modified analogues of m7GTP and m7Gppppm7G—Synthesis and biochemical propertiesZiemniak, Marcin / Kowalska, Joanna / Lukaszewicz, Maciej / Zuberek, Joanna / Wnek, Katarzyna / Darzynkiewicz, Edward / Jemielity, Jacek et al. | 2015
- 5382
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Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activityAtanasova, Mariyana / Stavrakov, Georgi / Philipova, Irena / Zheleva, Dimitrina / Yordanov, Nikola / Doytchinova, Irini et al. | 2015
- 5390
-
Synthesis and biological evaluation of (3′,5′-dichloro-2,6-dihydroxy-biphenyl-4-yl)-aryl/alkyl-methanone selective CB2 inverse agonistPresley, Chaela S. / Mustafa, Suni M. / Abidi, Ammaar H. / Moore, Bob M. II et al. | 2015
- 5402
-
Sulfation modulates the cell uptake, antiradical activity and biological effects of flavonoids in vitro: An examination of quercetin, isoquercitrin and taxifolinRoubalová, Lenka / Purchartová, Kateřina / Papoušková, Barbora / Vacek, Jan / Křen, Vladimír / Ulrichová, Jitka / Vrba, Jiří et al. | 2015
- 5410
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Guanidinium compounds with sub-micromolar activities against Mycobacterium tuberculosis. Synthesis, characterization and biological evaluationsMassimba-Dibama, Hugues / Mourer, Maxime / Constant, Patricia / Daffé, Mamadou / Regnouf-de-Vains, Jean-Bernard et al. | 2015
- 5419
-
Antimalarial benzoheterocyclic 4-aminoquinolines: Structure–activity relationship, in vivo evaluation, mechanistic and bioactivation studiesOngarora, Dennis S.B. / Strydom, Natasha / Wicht, Kathryn / Njoroge, Mathew / Wiesner, Lubbe / Egan, Timothy J. / Wittlin, Sergio / Jurva, Ulrik / Masimirembwa, Collen M. / Chibale, Kelly et al. | 2015
- 5433
-
Design, chemical synthesis and biological evaluation of 3-spiromorpholinone/3-spirocarbamate androsterone derivatives as inhibitors of 17β-hydroxysteroid dehydrogenase type 3Djigoué, Guy Bertrand / Kenmogne, Lucie Carolle / Roy, Jenny / Maltais, René / Poirier, Donald et al. | 2015
- 5452
-
Highly potent artemisinin-derived dimers and trimers: Synthesis and evaluation of their antimalarial, antileukemia and antiviral activitiesReiter, Christoph / Fröhlich, Tony / Gruber, Lisa / Hutterer, Corina / Marschall, Manfred / Voigtländer, Cornelia / Friedrich, Oliver / Kappes, Barbara / Efferth, Thomas / Tsogoeva, Svetlana B. et al. | 2015
- 5459
-
Molecular dynamics and density functional studies on the metabolic selectivity of antipsychotic thioridazine by cytochrome P450 2D6: Connection with crystallographic and metabolic resultsSasahara, Katsunori / Mashima, Akira / Yoshida, Tatsusada / Chuman, Hiroshi et al. | 2015
- 5466
-
Structural and computational study on inhibitory compounds for endonuclease activity of influenza virus polymeraseFudo, Satoshi / Yamamoto, Norio / Nukaga, Michiyoshi / Odagiri, Takato / Tashiro, Masato / Neya, Saburo / Hoshino, Tyuji et al. | 2015
- 5476
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Novel metal chelating molecules with anticancer activity. Striking effect of the imidazole substitution of the histidine–pyridine–histidine systemAli, Taha F.S. / Iwamaru, Kana / Ciftci, Halil Ibrahim / Koga, Ryoko / Matsumoto, Masahiro / Oba, Yasunori / Kurosaki, Hiromasa / Fujita, Mikako / Okamoto, Yoshinari / Umezawa, Kazuo et al. | 2015
- 5483
-
Discovery and structure of a new inhibitor scaffold of the autophagy initiating kinase ULK1Lazarus, Michael B. / Shokat, Kevan M. et al. | 2015
- 5489
-
Computer-aided identification, synthesis, and biological evaluation of novel inhibitors for botulinum neurotoxin serotype ATeng, Yu-Han Gary / Berger, William T. / Nesbitt, Natasha M. / Kumar, Kunal / Balius, Trent E. / Rizzo, Robert C. / Tonge, Peter J. / Ojima, Iwao / Swaminathan, Subramanyam et al. | 2015
- 5496
-
2- and 3-Fluoro-3-deazaneplanocins, 2-fluoro-3-deazaaristeromycins, and 3-methyl-3-deazaneplanocin: Synthesis and antiviral propertiesLiu, Chong / Chen, Qi / Gorden, John D. / Schneller, Stewart W. et al. | 2015
- 5502
-
Antimalarial activity of prodrugs of N-branched acyclic nucleoside phosphonate inhibitors of 6-oxopurine phosphoribosyltransferasesHocková, Dana / Janeba, Zlatko / Naesens, Lieve / Edstein, Michael D. / Chavchich, Marina / Keough, Dianne T. / Guddat, Luke W. et al. | 2015
- 5511
-
Design and synthesis of dithiocarbamate linked β-carboline derivatives: DNA topoisomerase II inhibition with DNA binding and apoptosis inducing abilityKamal, Ahmed / Sathish, Manda / Nayak, V. Lakshma / Srinivasulu, Vunnam / Kavitha, Botla / Tangella, Yellaiah / Thummuri, Dinesh / Bagul, Chandrakant / Shankaraiah, Nagula / Nagesh, Narayana et al. | 2015
- 5527
-
Novel diazabicycloalkane delta opioid agonistsLoriga, Giovanni / Lazzari, Paolo / Manca, Ilaria / Ruiu, Stefania / Falzoi, Matteo / Murineddu, Gabriele / Bottazzi, Mirko Emilio Heiner / Pinna, Giovanni / Pinna, Gérard Aimè et al. | 2015
- 5539
-
Discovery of a series of novel compounds with moderate anti-hepatitis C virus NS3 protease activity in vitroShi, Fangyuan / Zhang, Yingjie / Xu, Wenfang et al. | 2015
- 5546
-
Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558Takano, Rieko / Yoshida, Masao / Inoue, Masahiro / Honda, Takeshi / Nakashima, Ryutaro / Matsumoto, Koji / Yano, Tatsuya / Ogata, Tsuneaki / Watanabe, Nobuaki / Hirouchi, Masakazu et al. | 2015
- 5566
-
Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitorsWang, Zhen / Wong, Iris L.K. / Li, Fu Xing / Yang, Chao / Liu, Zhen / Jiang, Tao / Jiang, Ting Fu / Chow, Larry M.C. / Wan, Sheng Biao et al. | 2015
- 5574
-
Ethylenedioxy homologs of N-methyl-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) and its corresponding cathinone analog methylenedioxymethcathinone: Interactions with transporters for serotonin, dopamine, and norepinephrineDel Bello, Fabio / Sakloth, Farhana / Partilla, John S. / Baumann, Michael H. / Glennon, Richard A. et al. | 2015
- 5580
-
Addition of niclosamide to palladium(II) saccharinate complex of terpyridine results in enhanced cytotoxic activity inducing apoptosis on cancer stem cells of breast cancerKarakas, Didem / Cevatemre, Buse / Aztopal, Nazlihan / Ari, Ferda / Yilmaz, Veysel Turan / Ulukaya, Engin et al. | 2015
- 5587
-
The influence of the C5 substituent on the 2-thiouridine desulfuration pathway and the conformational analysis of the resulting 4-pyrimidinone productsBartos, Paulina / Ebenryter-Olbinska, Katarzyna / Sochacka, Elzbieta / Nawrot, Barbara et al. | 2015
- 5595
-
Chemoenzymatic synthesis and cytotoxicity of oenanthotoxin and analoguesSommerwerk, Sven / Heller, Lucie / Siewert, Bianka / Csuk, René et al. | 2015
- 5603
-
A P450 fusion library of heme domains from Rhodococcus jostii RHA1 and its evaluation for the biotransformation of drug moleculesKulig, Justyna K. / Spandolf, Claudia / Hyde, Ralph / Ruzzini, Antonio C. / Eltis, Lindsay D. / Grönberg, Gunnar / Hayes, Martin A. / Grogan, Gideon et al. | 2015
- 5610
-
Synthesis, biological evaluation and molecular modeling of new tetrahydroacridine derivatives as potential multifunctional agents for the treatment of Alzheimer’s diseaseBajda, Marek / Jończyk, Jakub / Malawska, Barbara / Czarnecka, Kamila / Girek, Małgorzata / Olszewska, Paulina / Sikora, Joanna / Mikiciuk-Olasik, Elżbieta / Skibiński, Robert / Gumieniczek, Anna et al. | 2015
- 5619
-
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moietiesCongiu, Cenzo / Onnis, Valentina / Deplano, Alessandro / Balboni, Gianfranco / Ceruso, Mariangela / Supuran, Claudiu T. et al. | 2015
- 5626
-
Evaluation of transition-state mimics in a superior BACE1 cleavage sequence as peptide-mimetic BACE1 inhibitorsHattori, Yasunao / Kobayashi, Kazuya / Deguchi, Ayaka / Nohara, Yukie / Akiyama, Tomomi / Teruya, Kenta / Sanjoh, Akira / Nakagawa, Atsushi / Yamashita, Eiki / Akaji, Kenichi et al. | 2015
- 5641
-
Synthesis of CNS active thyrotropin-releasing hormone (TRH)-like peptides: Biological evaluation and effect on cognitive impairment induced by cerebral ischemia in miceMeena, Chhuttan L. / Thakur, Avinash / Nandekar, Prajwal P. / Sangamwar, Abhay T. / Sharma, Shyam S. / Jain, Rahul et al. | 2015
- 5654
-
Imine/amide–imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-α inhibitionNegi, Arvind / Alex, Jimi Marin / Amrutkar, Suyog M. / Baviskar, Ashish T. / Joshi, Gaurav / Singh, Sandeep / Banerjee, Uttam C. / Kumar, Raj et al. | 2015
- 5662
-
Modification of N-(6-(2-methoxy-3-(4-fluorophenylsulfonamido)pyridin-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)acetamide as PI3Ks inhibitor by replacement of the acetamide group with alkylureaWang, Xiao-Meng / Mao, Shuai / Cao, Lei / Xie, Xiao-Xiao / Xin, Min-Hang / Lian, Jia-Fang / Cao, Yong-Xiao / Zhang, San-Qi et al. | 2015
- 5672
-
Antiproliferative and apoptosis-inducing activities of novel naphthalimide–cyclam conjugates through dual topoisomerase (topo) I/II inhibitionTan, Shaoying / Sun, Deheng / Lyu, Jiankun / Sun, Xiao / Wu, Fangshu / Li, Qiang / Yang, Yiqi / Liu, Jianxu / Wang, Xin / Chen, Zhuo et al. | 2015
- 5681
-
A-ring substituted 17β-arylsulfonamides of 17β-aminoestra-1,3,5(10)-trien-3-ol as highly potent reversible inhibitors of steroid sulfataseMostafa, Yaser A. / Kralt, Braden / Rao, Praveen P.N. / Taylor, Scott D. et al. | 2015
- 5693
-
Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogsOndachi, Pauline W. / Ye, Zhuo / Castro, Ana H. / Luetje, Charles W. / Damaj, M. Imad / Mascarella, S. Wayne / Navarro, Hernán A. / Carroll, F. Ivy et al. | 2015
- 5702
-
Factors that influence T box riboswitch efficacy and tRNA affinityZeng, C. / Zhou, S. / Bergmeier, S.C. / Hines, J.V. et al. | 2015
- 5709
-
The importance of the 6- and 7-positions of tetrahydroisoquinolines as selective antagonists for the orexin 1 receptorPerrey, David A. / Decker, Ann M. / Li, Jun-Xu / Gilmour, Brian P. / Thomas, Brian F. / Harris, Danni L. / Runyon, Scott P. / Zhang, Yanan et al. | 2015
- 5725
-
Identification of 2-aminopyrimidine derivatives as inhibitors of the canonical Wnt signaling pathwayDel Bello, Fabio / Farande, Aniket / Giannella, Mario / Piergentili, Alessandro / Quaglia, Wilma / Benicchi, Tiziana / Cappelli, Federico / Nencini, Arianna / Salerno, Massimiliano / Thomas, Russell J. et al. | 2015
- 5734
-
Novel fluorine-18 labeled 5-(1-pyrrolidinylsulfonyl)-7-azaisatin derivatives as potential PET tracers for in vivo imaging of activated caspases in apoptosisWaldmann, Christopher M. / Hermann, Sven / Faust, Andreas / Riemann, Burkhard / Schober, Otmar / Schäfers, Michael / Haufe, Günter / Kopka, Klaus et al. | 2015
- 5740
-
Optimization of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinolines as tubulin polymerization inhibitorsWang, Sheng-Biao / Wang, Xiao-Feng / Qin, Bingjie / Ohkoshi, Emika / Hsieh, Kan-Yen / Hamel, Ernest / Cui, Mu-Tian / Zhu, Dong-Qing / Goto, Masuo / Morris-Natschke, Susan L. et al. | 2015
- 5748
-
Dual inhibitors of the dengue and West Nile virus NS2B–NS3 proteases: Synthesis, biological evaluation and docking studies of novel peptide-hybridsBastos Lima, Allan / Behnam, Mira A.M. / El Sherif, Yasmin / Nitsche, Christoph / Vechi, Sergio M. / Klein, Christian D. et al. | 2015
- 5756
-
Cyclen-based double-tailed lipids for DNA delivery: Synthesis and the effect of linking group structuresZhang, Yi-Mei / Chang, De-Chun / Zhang, Ji / Liu, Yan-Hong / Yu, Xiao-Qi et al. | 2015
- 5764
-
Synthesis and structure–activity relationship of uracil nucleotide derivatives towards the identification of human P2Y6 receptor antagonistsMeltzer, Diana / Ethan, Ophir / Arguin, Guillaume / Nadel, Yael / Danino, Ortal / Lecka, Joanna / Sévigny, Jean / Gendron, Fernand-Pierre / Fischer, Bilha et al. | 2015
- 5774
-
Design, synthesis and biological evaluation of saccharin-based N-hydroxybenzamides as histone deacetylases (HDACs) inhibitorsFu, Huansheng / Han, Leiqiang / Hou, Xuben / Dun, Yanyan / Wang, Lei / Gong, Xiaowei / Fang, Hao et al. | 2015
- 5782
-
Role of polyol moiety of amphotericin B in ion channel formation and sterol selectivity in bilayer membraneYamamoto, Tomoya / Umegawa, Yuichi / Tsuchikawa, Hiroshi / Matsumori, Nobuaki / Hanashima, Shinya / Murata, Michio / Haser, Resul / Rawlings, Bernard J. / Caffrey, Patrick et al. | 2015
- 5789
-
Synthesis and antifungal evaluation of head-to-head and head-to-tail bisamidine compoundsNguyen, Son T. / Kwasny, Steven M. / Ding, Xiaoyuan / Williams, John D. / Peet, Norton P. / Bowlin, Terry L. / Opperman, Timothy J. et al. | 2015
- 5799
-
Synthesis and apoptotic activity of new pyrazole derivatives in cancer cell linesNitulescu, George Mihai / Draghici, Constantin / Olaru, Octavian Tudorel / Matei, Lilia / Ioana, Aldea / Dragu, Laura Denisa / Bleotu, Coralia et al. | 2015
- 5809
-
NMR-based conformational analysis of 2′,6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugsda Paixão Soares, Fábio / Groaz, Elisabetta / Lescrinier, Eveline / Neyts, Johan / Leyssen, Pieter / Herdewijn, Piet et al. | 2015
- 5816
-
Anti-inflammatory and antiproliferative evaluation of 4β-cinnamoyloxy,1β,3α-dihydroxyeudesm-7,8-ene from Verbesina persicifolia and derivativesDalla Via, L. / Mejia, M. / García-Argáez, A.N. / Braga, A. / Toninello, A. / Martínez-Vázquez, M. et al. | 2015
- 5829
-
Structure–activity studies of Wnt/β-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposureMook, Robert A. Jr. / Wang, Jiangbo / Ren, Xiu-Rong / Chen, Minyong / Spasojevic, Ivan / Barak, Larry S. / Lyerly, H. Kim / Chen, Wei et al. | 2015
- 5839
-
Design, synthesis and cytotoxicity studies of dithiocarbamate ester derivatives of emetine in prostate cancer cell linesAkinboye, Emmanuel S. / Bamji, Zebalda D. / Kwabi-Addo, Bernard / Ejeh, David / Copeland, Robert L. / Denmeade, Samuel R. / Bakare, Oladapo et al. | 2015
- 5846
-
Design, synthesis and immunological evaluation of 1,2,3-triazole-tethered carbohydrate–Pam3Cys conjugates as TLR2 agonistsNalla, Naresh / Pallavi, Preethi / Reddy, Bonam Srinivasa / Miryala, Sreekanth / Naveen Kumar, V. / Mahboob, Mohammed / Halmuthur, M. Sampath Kumar et al. | 2015
- 5856
-
Radiosynthesis of 4-[18F]fluoro-l-tryptophan by isotopic exchange on carbonyl-activated precursorsWeiss, Philipp S. / Ermert, Johannes / Castillo Meleán, Johnny / Schäfer, Dominique / Coenen, Heinz H. et al. | 2015
- 5870
-
Synthesis, kinetic mechanism and docking studies of vanillin derivatives as inhibitors of mushroom tyrosinaseAshraf, Zaman / Rafiq, Muhammad / Seo, Sung-Yum / Babar, Mustafeez Mujtaba / Zaidi, Najam-us-Sahar Sadaf et al. | 2015
- 5881
-
Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deacetylase inhibitorsYang, Wei / Li, Lixuan / Wang, Yulan / Wu, Xiaowei / Li, Tingting / Yang, Nan / Su, Mingbo / Sheng, Li / Zheng, Mingyue / Zang, Yi et al. | 2015
- 5891
-
Exploration of the nicotinamide-binding site of the tankyrases, identifying 3-arylisoquinolin-1-ones as potent and selective inhibitors in vitroPaine, Helen A. / Nathubhai, Amit / Woon, Esther C.Y. / Sunderland, Peter T. / Wood, Pauline J. / Mahon, Mary F. / Lloyd, Matthew D. / Thompson, Andrew S. / Haikarainen, Teemu / Narwal, Mohit et al. | 2015
- 5909
-
Efficient one-pot synthesis of CXCL14 and its derivative using an N-sulfanylethylanilide peptide as a peptide thioester equivalent and their biological evaluationTsuji, Kohei / Tanegashima, Kosuke / Sato, Kohei / Sakamoto, Ken / Shigenaga, Akira / Inokuma, Tsubasa / Hara, Takahiko / Otaka, Akira et al. | 2015
- 5915
-
Synthesis and biological evaluation of 9-N-oxamyl sialosides as Siglec-7 ligandsPrescher, Horst / Gütgemann, Stephan / Frank, Martin / Kuhfeldt, Elena / Watzl, Carsten / Brossmer, Reinhard et al. | 2015
- 5922
-
Identification of 2-[2-(4-tert-butylphenyl)ethyl]-N-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide (29) as an orally available MGAT2 inhibitorBusujima, Tsuyoshi / Tanaka, Hiroaki / Shirasaki, Yoshihisa / Munetomo, Eiji / Saito, Masako / Kitano, Kiyokazu / Minagawa, Toshiya / Yoshida, Koji / Osaki, Naoto / Sato, Nagaaki et al. | 2015
- 5932
-
Synthesis of mouse centromere-targeted polyamides and physico-chemical studies of their interaction with the target double-stranded DNANozeret, Karine / Bonan, Marc / Yarmoluk, Serguiy M. / Novopashina, Darya S. / Boutorine, Alexandre S. et al. | 2015
- 5946
-
Design and synthesis of new non nucleoside inhibitors of DNMT3AErdmann, Alexandre / Menon, Yoann / Gros, Christina / Molinier, Nicolas / Novosad, Natacha / Samson, Arnaud / Gregoire, Jean-Marc / Long, Christophe / Ausseil, Frédéric / Halby, Ludovic et al. | 2015
- 5954
-
Metabolically programmed iron chelatorsBergeron, Raymond J. / Bharti, Neelam / McManis, James S. / Wiegand, Jan et al. | 2015
- 5972
-
Synthesis and optical properties of chlorin monomer, dimer and trimer on an amino nitrogen atomTamiaki, Hitoshi / Nagai, Tomoaki / Tanaka, Takuya / Tatebe, Tomohiro et al. | 2015
- 5979
-
Anti-Plasmodium falciparum activity of quinoline–sulfonamide hybridsPinheiro, Luiz C.S. / Boechat, Núbia / Ferreira, Maria de Lourdes G. / Júnior, Carlos C.S. / Jesus, Antônio M.L. / Leite, Milene M.M. / Souza, Nicolli B. / Krettli, Antoniana U. et al. | 2015
- 5985
-
Chemical synthesis of tetracyclic terpenes and evaluation of antagonistic activity on endothelin-A receptors and voltage-gated calcium channelsLu, Jianyu / Aguilar, Angelo / Zou, Bende / Bao, Weier / Koldas, Serkan / Shi, Aibin / Desper, John / Wangemann, Philine / Xie, Xinmin Simon / Hua, Duy H. et al. | 2015
- 5999
-
Vinyl sulfone analogs of lysophosphatidylcholine irreversibly inhibit autotaxin and prevent angiogenesis in melanomaMurph, Mandi M. / Jiang, Guowei W. / Altman, Molly K. / Jia, Wei / Nguyen, Duy T. / Fambrough, Jada M. / Hardman, William J. / Nguyen, Ha T. / Tran, Sterling K. / Alshamrani, Ali A. et al. | 2015
- 6014
-
Synthesis of novel triazoles and a tetrazole of escitalopram as cholinesterase inhibitorsMehr-un-Nisa / Munawar, Munawar A. / Chattha, Fauzia A. / Kousar, Samina / Munir, Jawaria / Ismail, Tayaba / Ashraf, Muhammad / Khan, Misbahul A. et al. | 2015
- 6025
-
Development of indazolylpyrimidine derivatives as high-affine EphB4 receptor ligands and potential PET radiotracersEbert, Kristin / Wiemer, Jens / Caballero, Julio / Köckerling, Martin / Steinbach, Jörg / Pietzsch, Jens / Mamat, Constantin et al. | 2015
- 6036
-
Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4—The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS)St. John, Sarah E. / Tomar, Sakshi / Stauffer, Shaun R. / Mesecar, Andrew D. et al. | 2015
- 6049
-
Design and synthesis of new barbituric- and thiobarbituric acid derivatives as potent urease inhibitors: Structure activity relationship and molecular modeling studiesRauf, Abdul / Shahzad, Sohail / Bajda, Marek / Yar, Muhammad / Ahmed, Faiz / Hussain, Nazar / Akhtar, Muhammad Nadeem / Khan, Ajmal / Jończyk, Jakub et al. | 2015
- 6059
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Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton’s tyrosine kinase (BTK) inhibitorsZhao, Xinge / Xin, Minhang / Wang, Yazhou / Huang, Wei / Jin, Qiu / Tang, Feng / Wu, Gang / Zhao, Yong / Xiang, Hua et al. | 2015
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New acyloxy nitroso compounds with improved water solubility and nitroxyl (HNO) release kinetics and inhibitors of platelet aggregationMohamed, Heba A.H. / Abdel-Aziz, Mohamed / Abuo-Rahma, Gamal El-Din A.A. / King, S. Bruce et al. | 2015
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Corrigendum to “Discovery and structural analyses of S-adenosyl-l-homocysteine hydrolase inhibitors based on non-adenosine analogs” [Bioorg. Med. Chem. 23 (2015) 4952–4969]Nakao, Akira / Suzuki, Hiroko / Ueno, Hiroaki / Iwasaki, Hiroshi / Setsuta, Tomofumi / Kashima, Akiko / Sunada, Shinji et al. | 2015
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Corrigendum to “Discovery of novel tetrahydroisoquinoline derivatives as orally active N-type calcium channel blockers with high selectivity for hERG potassium channels” [Bioorg. Med. Chem. 22 (2014) 6899–6907]Ogiyama, Takashi / Inoue, Makoto / Honda, Shugo / Yamada, Hiroyoshi / Watanabe, Toshihiro / Gotoh, Takayasu / Kiso, Tetsuo / Koakutsu, Akiko / Kakimoto, Shuichiro / Shishikura, Jun-ichi et al. | 2015
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Instructions to contributors| 2015
- IFC
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Editorial board| 2015