Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels (Unknown)
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In:
Autophagy
;
17
, 12
;
4119-4140
;
2021
- Article (Journal) / Electronic Resource
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Title:Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levels
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Contributors:Bailus, Barbara J. ( author ) / Scheeler, Stephen M. ( author ) / Simons, Jesse ( author ) / Sanchez, Maria A. ( author ) / Tshilenge, Kizito-Tshitoko ( author ) / Creus-Muncunill, Jordi ( author ) / Naphade, Swati ( author ) / Lopez-Ramirez, Alejandro ( author ) / Zhang, Ningzhe ( author ) / Lakshika Madushani, Kuruwitage ( author )
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Published in:Autophagy ; 17, 12 ; 4119-4140
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Publisher:
- New search for: Taylor & Francis
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Publication date:2021-12-02
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Size:22 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:Unknown
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Keywords:
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Source:
Table of contents – Volume 17, Issue 12
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3895
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Look youse guys and gals, dat just ain’t rightKlionsky, Daniel J. et al. | 2021
- 3897
-
Class III phosphatidylinositol 3-kinase complex I subunit NRBF2/Atg38 - from cell and structural biology to health and diseaseOhashi, Yohei et al. | 2021
- 3908
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WDR45, one gene associated with multiple neurodevelopmental disordersCong, Yingying / So, Vincent / Tijssen, Marina A. J. / Verbeek, Dineke S. / Reggiori, Fulvio / Mauthe, Mario et al. | 2021
- 3924
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Coxsackievirus B3 targets TFEB to disrupt lysosomal functionMohamud, Yasir / Tang, Hui / Xue, Yuan Chao / Liu, Huitao / Ng, Chen Seng / Bahreyni, Amirhossein / Luo, Honglin et al. | 2021
- 3939
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KRT8 (keratin 8) attenuates necrotic cell death by facilitating mitochondrial fission-mediated mitophagy through interaction with PLEC (plectin)Baek, Ahruem / Son, Sumin / Baek, Yu Mi / Kim, Dong-Eun et al. | 2021
- 3957
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AMPK-dependent phosphorylation is required for transcriptional activation of TFEB and TFE3Paquette, Mathieu / El-Houjeiri, Leeanna / C. Zirden, Linda / Puustinen, Pietri / Blanchette, Paola / Jeong, Hyeonju / Dejgaard, Kurt / Siegel, Peter M. / Pause, Arnim et al. | 2021
- 3976
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CGAS is a micronucleophagy receptor for the clearance of micronucleiZhao, Mengmeng / Wang, Fei / Wu, Juehui / Cheng, Yuanna / Cao, Yajuan / Wu, Xiangyang / Ma, Mingtong / Tang, Fen / Liu, Zhi / Liu, Haipeng et al. | 2021
- 3992
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TNF-induced necroptosis initiates early autophagy events via RIPK3-dependent AMPK activation, but inhibits late autophagyWu, Wenxian / Wang, Xiaojing / Sun, Yadong / Berleth, Niklas / Deitersen, Jana / Schlütermann, David / Stuhldreier, Fabian / Wallot-Hieke, Nora / José Mendiburo, María / Cox, Jan et al. | 2021
- 4010
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Condition-dependent functional shift of two Drosophila Mtmr lipid phosphatases in autophagy controlManzéger, Anna / Tagscherer, Kinga / Lőrincz, Péter / Szaker, Henrik / Lukácsovich, Tamás / Pilz, Petra / Kméczik, Regina / Csikós, George / Erdélyi, Miklós / Sass, Miklós et al. | 2021
- 4029
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Modulation of the IGF1R-MTOR pathway attenuates motor neuron toxicity of human ALS SOD1G93A astrocytesGranatiero, Veronica / Sayles, Nicole M. / Savino, Angela M. / Konrad, Csaba / Kharas, Michael G. / Kawamata, Hibiki / Manfredi, Giovanni et al. | 2021
- 4043
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MED1 mediator subunit is a key regulator of hepatic autophagy and lipid metabolismZhou, Jin / Singh, Brijesh K. / Ho, Jia Pei / Lim, Andrea / Bruinstroop, Eveline / Ohba, Kenji / Sinha, Rohit A. / Yen, Paul M. et al. | 2021
- 4062
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Combination of autophagy and NFE2L2/NRF2 activation as a treatment approach for neuropathic painLi, Jian / Tian, Mouli / Hua, Tong / Wang, Haowei / Yang, Mei / Li, Wenqian / Zhang, Xiaoping / Yuan, Hongbin et al. | 2021
- 4083
-
Long noncoding RNA (lncRNA) EIF3J-DT induces chemoresistance of gastric cancer via autophagy activationLuo, Yuhao / Zheng, Siting / Wu, Qianying / Wu, Jianhua / Zhou, Rui / Wang, Chunling / Wu, Zhenzhen / Rong, Xiaoxiang / Huang, Na / Sun, Li et al. | 2021
- 4102
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CREG1 improves the capacity of the skeletal muscle response to exercise endurance via modulation of mitophagySong, HaiXu / Tian, Xiaoxiang / Liu, Dan / Liu, Meili / Liu, Yanxia / Liu, Jing / Mei, Zhu / Yan, Chenghui / Han, Yaling et al. | 2021
- 4119
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Modulating FKBP5/FKBP51 and autophagy lowers HTT (huntingtin) levelsBailus, Barbara J. / Scheeler, Stephen M. / Simons, Jesse / Sanchez, Maria A. / Tshilenge, Kizito-Tshitoko / Creus-Muncunill, Jordi / Naphade, Swati / Lopez-Ramirez, Alejandro / Zhang, Ningzhe / Lakshika Madushani, Kuruwitage et al. | 2021
- 4141
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Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolismLee, Tzu-Yin / Lu, Wan-Jung / Changou, Chun A. / Hsiung, Yuan-Chin / Trang, Nguyen T. T. / Lee, Cheng-Yang / Chang, Tzu-Hao / Jayakumar, Thanasekaran / Hsieh, Cheng-Ying / Yang, Chih-Hao et al. | 2021
- 4159
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PRDX1 activates autophagy via the PTEN-AKT signaling pathway to protect against cisplatin-induced spiral ganglion neuron damageLiu, Wenwen / Xu, Lei / Wang, Xue / Zhang, Daogong / Sun, Gaoying / Wang, Man / Wang, Mingming / Han, Yuechen / Chai, Renjie / Wang, Haibo et al. | 2021
- 4182
-
The role of mitophagy in the regulation of mitochondrial energetic status in neuronsHan, Sinsuk / Zhang, Mingyang / Jeong, Yu Young / Margolis, David J. / Cai, Qian et al. | 2021
- 4202
-
WLS/wntless is essential in controlling dendritic cell homeostasis via a WNT signaling-independent mechanismWang, Li-Ting / Lin, Ming-Hong / Liu, Kwei-Yan / Chiou, Shyh-Shin / Wang, Shen-Nien / Chai, Chee-Yin / Tseng, Li-Wen / Chiou, Hsin-Ying Clair / Wang, Hsueh-Chun / Yokoyama, Kazunari K. et al. | 2021
- 4218
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Augmenting ATG14 alleviates atherosclerosis and inhibits inflammation via promotion of autophagosome-lysosome fusion in macrophagesZhang, Hui / Ge, Song / Ni, Buqing / He, Keshuai / Zhu, Pengcheng / Wu, Xiaohong / Shao, Yongfeng et al. | 2021
- 4231
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TRIM28 functions as a negative regulator of aggresome formationChang, Jeeyoon / Hwang, Hyun Jung / Kim, Byungju / Choi, Yeon-Gil / Park, Joori / Park, Yeonkyoung / Lee, Ban Seok / Park, Heedo / Yoon, Min Ji / Woo, Jae-Sung et al. | 2021
- 4249
-
CREG1 promotes lysosomal biogenesis and functionLiu, Jie / Qi, Yanmei / Chao, Joshua / Sathuvalli, Pranav / Y. Lee, Leonard / Li, Shaohua et al. | 2021
- 4266
-
Ferritinophagy is involved in the zinc oxide nanoparticles-induced ferroptosis of vascular endothelial cellsQin, Xia / Zhang, Jun / Wang, Bin / Xu, Ge / Yang, Xi / Zou, Zhen / Yu, Chao et al. | 2021
- 4286
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Direct homophilic interaction of LAMP2A with the two-domain architecture revealed by site-directed photo-crosslinks and steric hindrances in mammalian cellsTerasawa, Kazue / Kato, Yuji / Ikami, Yuta / Sakamoto, Kensaku / Ohtake, Kazumasa / Kusano, Seisuke / Tomabechi, Yuri / Kukimoto-Niino, Mutsuko / Shirouzu, Mikako / Guan, Jun-Lin et al. | 2021
- 4305
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Deletion of Ulk1 inhibits neointima formation by enhancing KAT2A/GCN5-mediated acetylation of TUBA/α-tubulin in vivoOuyang, Changhan / Li, Jian / Zheng, Xiaoxu / Mu, Jing / Torres, Gloria / Wang, Qilong / Zou, Ming-Hui / Xie, Zhonglin et al. | 2021
- 4323
-
CUL3 (cullin 3)-mediated ubiquitination and degradation of BECN1 (beclin 1) inhibit autophagy and promote tumor progressionLi, Xuan / Yang, Kai-Bin / Chen, Wei / Mai, Jia / Wu, Xiao-Qi / Sun, Ting / Wu, Rui-Yan / Jiao, Lin / Li, Dan-Dan / Ji, Jiao et al. | 2021
- 4341
-
FOXG1 promotes aging inner ear hair cell survival through activation of the autophagy pathwayHe, Zu-Hong / Li, Ming / Fang, Qiao-Jun / Liao, Fu-Ling / Zou, Sheng-Yu / Wu, Xia / Sun, Hai-Ying / Zhao, Xue-Yan / Hu, Yu-Juan / Xu, Xiao-Xiang et al. | 2021
- 4363
-
Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiologyEl Manaa, Wejdane / Duplan, Eric / Goiran, Thomas / Lauritzen, Inger / Vaillant Beuchot, Loan / Lacas-Gervais, Sandra / Morais, Vanessa Alexandra / You, Han / Qi, Ling / Salazar, Mario et al. | 2021
- 4386
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Acetylation-dependent regulation of TPD52 isoform 1 modulates chaperone-mediated autophagy in prostate cancerFan, Yizeng / Hou, Tao / Gao, Yang / Dan, Weichao / Liu, Tianjie / Liu, Bo / Chen, Yule / Xie, Hongjun / Yang, Zhao / Chen, Jiaqi et al. | 2021
- 4401
-
MCOLN1/TRPML1 finely controls oncogenic autophagy in cancer by mediating zinc influxQi, Jiansong / Xing, Yanhong / Liu, Yucheng / Wang, Meng-Meng / Wei, Xiangqing / Sui, Zhongheng / Ding, Lin / Zhang, Yang / Lu, Chen / Fei, Yuan-Hui et al. | 2021
- 4423
-
HBx induces hepatocellular carcinogenesis through ARRB1-mediated autophagy to drive the G1/S cycleLei, Yiming / Xu, Xuan / Liu, Huiling / Chen, Lingjun / Zhou, Haoxiong / Jiang, Jie / Yang, Yidong / Wu, Bin et al. | 2021
- 4442
-
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesisFormica, Miriam / Storaci, Alessandra Maria / Bertolini, Irene / Carminati, Francesca / Knævelsrud, Helene / Vaira, Valentina / Vaccari, Thomas et al. | 2021
- 4453
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Atg9-centered multi-omics integration reveals new autophagy regulators in Saccharomyces cerevisiaePeng, Di / Ruan, Chen / Fu, Shanshan / He, Chengwen / Song, Jingzhen / Li, Hui / Tu, Yiran / Tang, Dachao / Yao, Lan / Lin, Shaofeng et al. | 2021
- 4477
-
Comment on “mt-Keima detects PINK1-PRKN mitophagy in vivo with greater sensitivity than mito-QC”Ganley, Ian G. / Whitworth, Alexander J. / McWilliams, Thomas G. et al. | 2021
- 4480
-
Autophagy promotes mitochondrial respiration by providing serine for one-carbon-metabolismKumar, Rajesh / Reichert, Andreas S. et al. | 2021
- 4486
-
Targeting lipid droplets for autophagic degradation by ATTECFu, Yuhua / Lu, Boxun et al. | 2021
- 4489
-
Impairment of ULK1 sulfhydration-mediated lipophagy by SREBF1/SREBP-1c in hepatic steatosisNguyen, Thuy T.P. / Kim, Do-Young / Im, Seung-Soon / Jeon, Tae-Il et al. | 2021
- 4491
-
The ingenious ULKs: expanding the repertoire of the ULK complex with phosphoproteomicsMercer, Thomas J. / Tooze, Sharon A. et al. | 2021
- 4494
-
Deathly triangle for pancreatic β-cells: Hippo pathway-MTORC1-autophagyArdestani, Amin / Maedler, Kathrin et al. | 2021
- 4497
-
Autophagy in host stromal fibroblasts supports tumor desmoplasiaRudnick, Jenny A. / Debnath, Jayanta et al. | 2021
- 4499
-
A new type of membrane contact in the ER-Golgi system regulates autophagosome biogenesisLi, Shulin / Zhang, Min / Ge, Liang et al. | 2021
- 4502
-
Loss-of-function mutation in VCP mimics the characteristic pathology as in FTLD-TARDBPWani, Abubakar / Weihl, Conrad C. et al. | 2021
- 4504
-
EIF4A3: a gatekeeper of autophagySakellariou, Despoina / Frankel, Lisa B. et al. | 2021
- 4506
-
The pro-autophagic protein AMBRA1 coordinates cell cycle progression by regulating CCND (cyclin D) stabilityMaiani, Emiliano / Milletti, Giacomo / Cecconi, Francesco et al. | 2021
- 4509
-
Endothelial cell autophagy keeps neutrophil trafficking under controlReglero-Real, Natalia / Pérez-Gutiérrez, Lorena / Nourshargh, Sussan et al. | 2021
- 4512
-
A conserved Vac8/ARMC3-PtdIns3K-CI cascade regulates autophagy initiation and functions in spermiogenesis by promoting ribophagyLei, Yuqing / Zhang, Xueguang / Xu, Qingjia / Liu, Shiyan / Li, Chunxia / Jiang, Hui / Lin, Haocheng / Kong, Eryan / Liu, Jiaming / Qi, Shiqian et al. | 2021
- 4515
-
Correction| 2021