RBD- specific Th1 responses are associated with vaccine-induced protection against SARS-CoV-2 infection in patients with hematological malignancies (English)
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In:
OncoImmunology
;
12
, 1
;
2023
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ISSN:
- Article (Journal) / Electronic Resource
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Title:RBD- specific Th1 responses are associated with vaccine-induced protection against SARS-CoV-2 infection in patients with hematological malignancies
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Contributors:Bigenwald, Camille ( author ) / Haddad, Yacine ( author ) / Thelemaque, Cassandra ( author ) / Carrier, Agathe ( author ) / Birebent, Roxanne ( author ) / Ly, Pierre ( author ) / Flament, Caroline ( author ) / Lahmar, Imran ( author ) / de Sousa, Eric ( author ) / Maeurer, Markus ( author )
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Published in:OncoImmunology ; 12, 1
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Publisher:
- New search for: Taylor & Francis
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Publication date:2023-12-31
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Keywords:
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Source:
Table of contents – Volume 12, Issue 1
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
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The signaling function of IDO1 incites the malignant progression of mouse B16 melanomaOrecchini, E / Belladonna, ML / Pallotta, MT / Volpi, C / Zizi, L / Panfili, E / Gargaro, M / Fallarino, F / Rossini, S / Suvieri, C et al. | 2023
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B cells require licensing by dendritic cells to serve as primary antigen-presenting cells for plasmid DNARastogi, Ichwaku / McNeel, Douglas G. et al. | 2023
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CD8 T cell-mediated depletion of HBV surface-antigen-expressing, bilineal-differentiated liver carcinoma cells generates highly aggressive escape variantsQiu, Na / Srikanth, Akshaya / Mulaw, Medhanie / Tharehalli, Umesh / Selvachandran, Shanthiya / Wagner, Martin / Seufferlein, Thomas / Stifter, Katja / Lechel, André / Schirmbeck, Reinhold et al. | 2023
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Preclinical evaluation of chimeric antigen receptor T cells targeting the carcinoembryonic antigen as a potential immunotherapy for gallbladder cancerLopez, Ernesto / Hidalgo, Sofía / Roa, Eduardo / Gómez, Javiera / Hermansen Truan, Carlos / Sanders, Evy / Carrasco, Cristian / Pacheco, Rodrigo / Salazar-Onfray, Flavio / Varas-Godoy, Manuel et al. | 2023
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In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapiesGalat, Yekaterina / Du, Yuchen / Perepitchka, Mariana / Li, Xiao-Nan / Balyasnikova, Irina V / Tse, William T / Dambaeva, Svetlana / Schneiderman, Sylvia / Iannaccone, Philip M / Becher, Oren et al. | 2023
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The yes-associated protein (YAP) is associated with resistance to anti-GD2 immunotherapy in neuroblastoma through downregulation of ST8SIA1Pilgrim, Adeiye A. / Jonus, Hunter C. / Ho, Andrew / Cole, Anna C. / Shim, Jenny / Goldsmith, Kelly C. et al. | 2023
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Melanoma patients with immune-related adverse events after immune checkpoint inhibitors are characterized by a distinct immunological phenotype of circulating T cells and M-MDSCsLepper, Alisa / Bitsch, Rebekka / Özbay Kurt, Feyza Gül / Arkhypov, Ihor / Lasser, Samantha / Utikal, Jochen / Umansky, Viktor et al. | 2023
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Lag-3 expression and clinical outcomes in metastatic melanoma patients treated with combination anti-lag-3 + anti-PD-1-based immunotherapiesGide, Tuba N. / Paver, Elizabeth C. / Yaseen, Zarwa / Maher, Nigel / Adegoke, Nurudeen / Menzies, Alexander M. / Pires da Silva, Ines / Wilmott, James S. / Long, Georgina V. / Scolyer, Richard A. et al. | 2023
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A novel Fc-enhanced humanized monoclonal antibody targeting B7-H3 suppresses the growth of ESCCWu, Huiting / Liu, Chang / Yuan, Qiang / Qiao, Yan / Ding, Yongwei / Duan, Lina / Li, Wenjing / Zhang, Mengjia / Zhang, Xuhua / Jiang, Yanan et al. | 2023
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Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapyVaxevanis, Christoforos K. / Bauer, Marcus / Subbarayan, Karthikeyan / Friedrich, Michael / Massa, Chiara / Biehl, Katharina / Al-Ali, Haifa Kathrin / Wickenhauser, Claudia / Seliger, Barbara et al. | 2023
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Altered phenotypic and metabolic characteristics of FOXP3+CD3+CD56+ natural killer T (NKT)-like cells in human malignant pleural effusionWang, Zi-Hao / Zhang, Pei / Peng, Wen-Bei / Ye, Lin-Lin / Xiang, Xuan / Wei, Xiao-Shan / Niu, Yi-Ran / Zhang, Si-Yu / Xue, Qian-Qian / Wang, Hao-Lei et al. | 2023
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The inhibitory NKR-P1B receptor regulates NK cell-mediated mammary tumor immunosurveillance in miceAl Olabi, Raghd / Hendy, Abd El Aziz / Alkassab, Mohamad Basem / Alnajm, Karla / Elias, Manahel / Ibrahim, Mary / Carlyle, James R. / Makrigiannis, Andrew P. / Rahim, Mir Munir A et al. | 2023
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Trial watch: Toll-like receptor ligands in cancer therapyLe Naour, Julie / Kroemer, Guido et al. | 2023
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ELK3-CXCL16 axis determines natural killer cell cytotoxicity via the chemotactic activity of CXCL16 in triple negative breast cancerJung, Hae-Yun / Lee, Dae-Keum / Lee, Minwook / Choi, Seung Hee / Park, Joo Dong / Ko, Eun-Su / Lee, Jongwon / Park, Kyung-Soon et al. | 2023
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Phenotypic characterization of spatial immune infiltration niches in non-small cell lung cancerSandström Gerdtsson, Anna / Knulst, Mattis / Botling, Johan / Mezheyeuski, Artur / Micke, Patrick / Ek, Sara et al. | 2023
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Acquired DNA damage repairs deficiency-driven immune evolution and involved immune factors of local versus distant metastases in non-small cell lung cancerTang, Wen-Fang / Fan, Xiao-Jun / Bao, Hua / Fu, Rui / Liang, Yi / Wu, Min / Zhang, Chao / Su, Jian / Wu, Yi-Long / Zhong, Wen-Zhao et al. | 2023
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Trial watch: an update of clinical advances in photodynamic therapy and its immunoadjuvant properties for cancer treatmentPenetra, Mafalda / Arnaut, Luís G. / Gomes-da-Silva, Lígia C. et al. | 2023
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Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conferenceGregucci, Fabiana / Spada, Sheila / Barcellos-Hoff, Mary Helen / Bhardwaj, Nina / Chan Wah Hak, Charleen / Fiorentino, Alba / Guha, Chandan / Guzman, Monica L. / Harrington, Kevin / Herrera, Fernanda G. et al. | 2023
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Histamine antagonists promote cancer immunosurveillanceLiu, Peng / Kroemer, Guido / Kepp, Oliver et al. | 2023
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L-Kynurenine participates in cancer immune evasion by downregulating hypoxic signaling in T lymphocytesSchlichtner, Stephanie / Yasinska, Inna M. / Klenova, Elena / Abooali, Maryam / Lall, Gurprit S. / Berger, Steffen M. / Ruggiero, Sabrina / Cholewa, Dietmar / Milošević, Milan / Gibbs, Bernhard F. et al. | 2023
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Preclinical characterization of an mRNA-encoded anti-Claudin 18.2 antibodyBähr-Mahmud, Hayat / Ellinghaus, Ursula / Stadler, Christiane R. / Fischer, Leyla / Lindemann, Claudia / Chaturvedi, Anuhar / Diekmann, Jan / Wöll, Stefan / Biermann, Imke / Hebich, Bernhard et al. | 2023
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Safety and effectiveness of combination versus monotherapy with immune checkpoint inhibitors in patients with preexisting autoimmune diseasesReid, Pankti / Sandigursky, Sabina / Song, Juhee / Lopez-Olivo, Maria A. / Safa, Houssein / Cytryn, Samuel / Efuni, Elizaveta / Buni, Maryam / Pavlick, Anna / Krogsgaard, Michelle et al. | 2023
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Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemiaFernandez Botana, Iria / Pagano, Giulia / Moussay, Etienne / Paggetti, Jerome et al. | 2023
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Plasma galectins and metabolites in advanced head and neck carcinomas: evidence of distinct immune characteristics linked to hypopharyngeal tumorsTran, Bao-Tram Thi / Gelin, Aurore / Durand, Sylvère / Texier, Matthieu / Daste, Amaury / Toullec, Clémence / Benihoud, Karim / Breuskin, Ingrid / Gorphe, Philippe / Garic, Florence et al. | 2023
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Suppression of prostate cancer and amelioration of the immunosuppressive tumor microenvironment through selective immunoproteasome inhibitionKoerner, Julia / Horvath, Dennis / Oliveri, Franziska / Li, Jun / Basler, Michael et al. | 2023
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Thiopurine 6TG treatment increases tumor immunogenicity and response to immune checkpoint blockadeNazerai, Loulieta / Willis, Shona Caroline / Yankilevich, Patricio / Di Leo, Luca / Bosisio, Francesca Maria / Frias, Alex / Bertolotto, Corine / Nersting, Jacob / Thastrup, Maria / Buus, Soren et al. | 2023
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Tumor-infiltrating lymphocytes for melanoma immunotherapyKepp, Oliver / Liu, Peng / Zitvogel, Laurence / Kroemer, Guido et al. | 2023
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Rare immune-related adverse events in patients with melanoma: incidence, spectrum, and clinical presentationsPark, Benjamin C. / Narayanan, Sathya / Gavralidis, Alexander / Ye, Fei / Fan, Run / Sullivan, Ryan J. / Boland, Genevieve / Reynolds, Kerry L / Balko, Justin M. / Carlino, Matteo S. et al. | 2023
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Targeting CD70 in combination with chemotherapy to enhance the anti-tumor immune effects in non-small cell lung cancerFlieswasser, Tal / Van den Eynde, Astrid / Freire Boullosa, Laurie / Melis, Jöran / Hermans, Christophe / Merlin, Céline / Lau, Ho Wa / Van Audenaerde, Jonas / Lardon, Filip / Smits, Evelien et al. | 2023
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Early response evaluation of PD-1 blockade in NSCLC patients through FDG-PET-CT and T cell profiling of tumor-draining lymph nodesBorm, Frank J. / Smit, Jasper / Bakker, Joyce / Wondergem, Maurits / Smit, Egbert F. / de Langen, Adrianus J. / de Gruijl, Tanja D. et al. | 2023
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Trial watch: chemotherapy-induced immunogenic cell death in oncologySprooten, Jenny / Laureano, Raquel S. / Vanmeerbeek, Isaure / Govaerts, Jannes / Naulaerts, Stefan / Borras, Daniel M. / Kinget, Lisa / Fucíková, Jitka / Špíšek, Radek / Jelínková, Lenka Palová et al. | 2023
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Group 2 innate lymphoid cells boost CD8+ T-cell activation in anti-tumor immune responsesWen, Jing / Cheng, Shipeng / Wang, Ran / Huang, Yuying / Xu, Long / Ma, Liyan / Ling, Zhiyang / Xu, Jinfu / Zhao, Deping / Zhang, Yaguang et al. | 2023
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CD40 agonism improves anti-tumor T cell priming induced by the combination of radiation therapy plus CTLA4 inhibition and enhances tumor responseCharpentier, Maud / Formenti, Silvia / Demaria, Sandra et al. | 2023
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Listeria-based vaccination against the pericyte antigen RGS5 elicits anti-vascular effects and colon cancer protectionAnderson, Trevor S. / McCormick, Amanda L. / Daugherity, Elizabeth A. / Oladejo, Mariam / Okpalanwaka, Izuchukwu F. / Smith, Savanna L. / Appiah, Duke / Wood, Laurence M. / Lowe, Devin B. et al. | 2023
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CD4+ T cell-derived IL-22 enhances liver metastasis by promoting angiogenesisZhang, Tao / Wahib, Ramez / Zazara, Dimitra E. / Lücke, Jöran / Shiri, Ahmad Mustafa / Kempski, Jan / Zhao, Lilan / Agalioti, Theodora / Machicote, Andres Pablo / Giannou, Olympia et al. | 2023
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Emergence of immune-related adverse events correlates with pathological complete response in patients receiving pembrolizumab for early triple-negative breast cancerMarhold, Maximilian / Udovica, Simon / Halstead, Anna / Hirdler, Mona / Ferner, Muna / Wimmer, Kerstin / Bago-Horvath, Zsuzsanna / Exner, Ruth / Fitzal, Florian / Strasser-Weippl, Kathrin et al. | 2023
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Stereotactic Ablative Radiation Therapy in 3 Fractions Induces a Favorable Systemic Immune Cell Profiling in Prostate Cancer PatientsPalermo, Belinda / Bottero, Marta / Panetta, Mariangela / Faiella, Adriana / Sperduti, Isabella / Masi, Serena / Frisullo, Giuseppe / Foddai, Maria Laura / Cordone, Iole / Nisticò, Paola et al. | 2023
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Anti-CD122 antibody restores specific CD8+ T cell response in nonalcoholic steatohepatitis and prevents hepatocellular carcinoma growthLacotte, Stéphanie / Slits, Florence / Moeckli, Beat / Peloso, Andrea / Koenig, Stéphane / Tihy, Matthieu / El Hajji, Sofia / Gex, Quentin / Rubbia-Brandt, Laura / Toso, Christian et al. | 2023
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Intratumoral neoadjuvant immunotherapy based on the BO-112 viral RNA mimeticAlvarez, Maite / Molina, Carmen / Garasa, Saray / Ochoa, Maria C. / Rodriguez-Ruiz, Maria E / Gomis, Gabriel / Cirella, Assunta / Olivera, Irene / Glez-Vaz, Javier / Gonzalez-Gomariz, Jose et al. | 2023
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Non-small cell lung cancer patients treated with Anti-PD1 immunotherapy show distinct microbial signatures and metabolic pathways according to progression-free survival and PD-L1 statusDora, David / Ligeti, Balazs / Kovacs, Tamas / Revisnyei, Peter / Galffy, Gabriella / Dulka, Edit / Krizsán, Dániel / Kalcsevszki, Regina / Megyesfalvi, Zsolt / Dome, Balazs et al. | 2023
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T-cell dysfunction in natural killer/T-cell lymphomaFeng, Xiaoyan / Meng, Miaomiao / Li, Hongwen / Gao, Yuyang / Song, Wenting / Di, Ruiqing / Li, Zhaoming / Zhang, Xudong / Zhang, Mingzhi et al. | 2023
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FXR agonist GW4064 enhances anti-PD-L1 immunotherapy in colorectal cancerLu, Lu / Jiang, Yi-Xin / Liu, Xiao-Xia / Jin, Jin-Mei / Gu, Wen-Jie / Luan, Xin / Guan, Ying-Yun / Zhang, Li-Jun et al. | 2023
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23ME-00610, a genetically informed, first-in-class antibody targeting CD200R1 to enhance antitumor T cell functionFenaux, Jill / Fang, Xin / Huang, Yao-ming / Melero, Cristina / Bonnans, Caroline / Lowe, Earth Light / Palumbo, Tiziana / Lay, Cecilia / Yi, Zuoan / Zhou, Aileen et al. | 2023
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MicroRNA analysis of Natural Killer cell-derived exosomes: the microRNA let-7b-5p is enriched in exosomes and participates in their anti-tumor effects against pancreatic cancer cellsDi Pace, Anna Laura / Pelosi, Andrea / Fiore, Piera Filomena / Tumino, Nicola / Besi, Francesca / Quatrini, Linda / Santopolo, Silvia / Vacca, Paola / Moretta, Lorenzo et al. | 2023
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Bile acids regulate MAdCAM-1 expression to link the gut microbiota to cancer immunosurveillanceFidelle, Marine / Tian, Ai-Ling / Zitvogel, Laurence / Kroemer, Guido et al. | 2023
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Short-term immune-checkpoint inhibition partially rescues perturbed bone marrow hematopoiesis in mismatch-repair deficient tumorsKrone, Paula / Wolff, Annabell / Teichmann, Julia / Maennicke, Johanna / Henne, Julia / Engster, Leonie / Salewski, Inken / Bergmann, Wendy / Junghanss, Christian / Maletzki, Claudia et al. | 2023
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Spatial heterogeneity of T cell repertoire across NSCLC tumors, tumor edges, adjacent and distant lung tissuesHu, Qikang / Frank, Meredith L. / Gao, Yang / Ji, Liyan / Peng, Muyun / Chen, Chen / Wang, Bin / Hu, Yan / Wu, Zeyu / Li, Jina et al. | 2023
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Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancerKudling, Tatiana V. / Clubb, James H.A. / Pakola, Santeri / Quixabeira, Dafne C.A. / Lähdeniemi, Iris A.K. / Heiniö, Camilla / Arias, Victor / Havunen, Riikka / Cervera-Carrascon, Victor / Santos, Joao M. et al. | 2023
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Chemoimmunotherapy triggers immune responses targeting microsatellite stable colorectal cancerThibaudin, Marion / Ghiringhelli, Francois et al. | 2023
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A mitochondrial checkpoint to adaptive anticancer immunityKepp, Oliver / Liu, Peng / Kroemer, Guido / Galluzzi, Lorenzo et al. | 2023
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Whole stromal fibroblast signature is linked to specific chemokine and immune infiltration patterns and to improved survival in NSCLCKoeck, Stefan / Amann, Arno / Kern, Johan / Zwierzina, Marit / Lorenz, Edith / Sopper, Sieghart / Zwierzina, Heinz / Mildner, Finn / Sykora, Martina / Sprung, Susanne et al. | 2023
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Tumor-intrinsic RGS1 potentiates checkpoint blockade response via ATF3-IFNGR1 axisWang, Baojun / Jiang, Bo / Du, Lin / Chen, Wenyuan / Zhang, Qing / Chen, Wei / Ding, Meng / Cao, Wenmin / Gao, Jie / Deng, Yongming et al. | 2023
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Intracavitary adoptive transfer of IL-12 mRNA-engineered tumor-specific CD8+ T cells eradicates peritoneal metastases in mouse modelsDi Trani, Claudia Augusta / Cirella, Assunta / Arrizabalaga, Leire / Bella, Ángela / Fernandez-Sendin, Myriam / Russo-Cabrera, Joan Salvador / Gomar, Celia / Olivera, Irene / Bolaños, Elizabeth / González-Gomariz, José et al. | 2023
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BCG-activation of leukocytes is sufficient for the generation of donor-independent innate anti-tumor NK and γδ T-cells that can be further expanded in vitroEsteso, Gloria / Felgueres, María José / García-Jiménez, Álvaro F. / Reyburn-Valés, Christina / Benguría, Alberto / Vázquez, Enrique / Reyburn, Hugh T. / Aguiló, Nacho / Martín, Carlos / Puentes, Eugenia et al. | 2023
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RBD- specific Th1 responses are associated with vaccine-induced protection against SARS-CoV-2 infection in patients with hematological malignanciesBigenwald, Camille / Haddad, Yacine / Thelemaque, Cassandra / Carrier, Agathe / Birebent, Roxanne / Ly, Pierre / Flament, Caroline / Lahmar, Imran / de Sousa, Eric / Maeurer, Markus et al. | 2023
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CD25bright NK cells display superior function and metabolic activity under regulatory T cell-mediated suppressionChen, Ziqing / Tong, Le / Neo, Shi Yong / Li, Shuijie / Gao, Jiwei / Schlisio, Susanne / Lundqvist, Andreas et al. | 2023
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Melanoma-associated repair-like Schwann cells suppress anti-tumor T-cells via 12/15-LOX/COX2-associated eicosanoid productionKruglov, Oleg / Vats, Kavita / Soman, Vishal / Tyurin, Vladimir A. / Tyurina, Yulia Y. / Wang, Jiefei / Williams, Li’an / Zhang, Jiying / Donahue Carey, Cara / Jaklitsch, Erik et al. | 2023
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Immunotherapy with IL12 and PD1/CTLA4 inhibition is effective in advanced ovarian cancer and associates with reversal of myeloid cell-induced immunosuppressionPavicic, Paul G.Jr. / Rayman, Patricia A. / Swaidani, Shadi / Rupani, Amit / Makarov, Vladimir / Tannenbaum, Charles S. / Edwards, Robert P. / Vlad, Anda M. / Diaz-Montero, C. Marcela / Mahdi, Haider et al. | 2023
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Studying TIGIT activity against tumors through the generation of knockout miceRishiq, Ahmed / Bsoul, Reem / Pick, Ophir / Mandelboim, Ofer et al. | 2023
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Longitudinal immune monitoring of patients with resectable esophageal adenocarcinoma treated with Neoadjuvant PD-L1 checkpoint inhibitionvan den Ende, Tom / Ezdoglian, Aiarpi / Baas, Lisanne M. / Bakker, Joyce / Lougheed, Sinéad M. / Harrasser, Micaela / Waasdorp, Cynthia / van Berge Henegouwen, Mark I. / Hulshof, Maarten C.C.M. / Haj Mohammad, Nadia et al. | 2023
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CAR-T cells dual-target CD123 and NKG2DLs to eradicate AML cells and selectively target immunosuppressive cellsJin, Xin / Xie, Danni / Sun, Rui / Lu, Wenyi / Xiao, Xia / Yu, Yibing / Meng, Juanxia / Zhao, Mingfeng et al. | 2023
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Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patientsGarcía-Mulero, Sandra / Fornelino, Roberto / Punta, Marco / Lise, Stefano / Varela, Mar / del Carpio, Luis P. / Moreno, Rafael / Costa-García, Marcel / Rieder, Dietmar / Trajanoski, Zlatko et al. | 2023
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Dipeptidyl peptidase 4 inhibition sensitizes radiotherapy by promoting T cell infiltrationTian, Yu / Kong, Lingyi / Li, Yan / Liao, Zhiyun / Cai, Xing / Deng, Suke / Yang, Xiao / Zhang, Bin / Wang, Yijun / Zhang, Zhanjie et al. | 2023
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The significance of the omentum in locoregional immunotherapy for peritoneal carcinomatosisBella, Ángela / Melero, Ignacio / Berraondo, Pedro / Aranda, Fernando et al. | 2023
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In vivo dynamics and anti-tumor effects of EpCAM-directed CAR T-cells against brain metastases from lung cancerXu, Tao / Karschnia, Philipp / Cadilha, Bruno Loureiro / Dede, Sertac / Lorenz, Michael / Seewaldt, Niklas / Nikolaishvili, Elene / Müller, Katharina / Blobner, Jens / Teske, Nico et al. | 2023
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Neoadjuvant immune checkpoint blockade triggers persistent and systemic Treg activation which blunts therapeutic efficacy against metastatic spread of breast tumorsBlomberg, Olga S. / Kos, Kevin / Spagnuolo, Lorenzo / Isaeva, Olga I. / Garner, Hannah / Wellenstein, Max D. / Bakker, Noor / Duits, Danique E.M. / Kersten, Kelly / Klarenbeek, Sjoerd et al. | 2023
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Preexisting autoantibodies as predictor of immune related adverse events (irAEs) for advanced solid tumors treated with immune checkpoint inhibitors (ICIs)Daban, A / Gonnin, C / Phan, L / Saldmann, A / Granier, C / Lillo-Lelouet, A / Le Beller, C / Pouchot, J / Weiss, l / Tartour, E et al. | 2023
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Trial watch: immunotherapeutic strategies on the horizon for hepatocellular carcinomaKoh, Benjamin / Tan, Darren Jun Hao / Lim, Wen Hui / Wong, Jeffrey S L / Ng, Cheng Han / Chan, Kai En / Wang, Meng / Yong, Wei Peng / Dan, Yock Young / Wang, Louis Z et al. | 2023
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Eribulin mesylate exerts antitumor effects via CD103Oya, Kazumasa / Nakamura, Yoshiyuki / Watanabe, Rei / Tanaka, Ryota / Ichimura, Yuki / Kubota, Noriko / Matsumura, Yutaka / Tahara, Hideaki / Okiyama, Naoko / Fujimoto, Manabu et al. | 2023
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Decreased melanoma CSF-1 secretion by Cannabigerol treatment reprograms regulatory myeloid cells and reduces tumor progressionWyrobnik, Iris / Steinberg, Miryam / Gelfand, Anat / Rosenblum, Ronen / Eid Mutlak, Yara / Sulimani, Liron / Procaccia, Shiri / Ofran, Yishai / Novak-Kotzer, Hila / Meiri, David et al. | 2023
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Stem cell-like T cell depletion in the recurrent head and neck cancer immune microenvironmentChen, Linda / Lee, Nancy / Sarkar, Reith / Katabi, Nora / Li, Yanyun / Morris, Luc / Wong, Richard / Sherman, Eric / Reis-Filho, Jorge S. / Hollmann, Travis et al. | 2023
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Chemotherapy-induced neutropenia elicits metastasis formation in mice by promoting proliferation of disseminated tumor cellsRusso, Massimo / Panini, Nicolò / Fabbrizio, Paola / Formenti, Laura / Becchetti, Riccardo / Matteo, Cristina / Meroni, Marina / Nastasi, Claudia / Cappelleri, Andrea / Frapolli, Roberta et al. | 2023
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Non-pharmaceutical interventions to optimize cancer immunotherapyBoesch, Maximilian / Baty, Florent / Rassouli, Frank / Kowatsch, Tobias / Joerger, Markus / Früh, Martin / Brutsche, Martin H. et al. | 2023
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C5aR1 blockade reshapes immunosuppressive tumor microenvironment and synergizes with immune checkpoint blockade therapy in high-grade serous ovarian cancerZhang, Chen / Cao, Kankan / Yang, Moran / Wang, Yiying / He, Mengdi / Lu, Jiaqi / Huang, Yan / Zhang, Guodong / Liu, Haiou et al. | 2023
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Interleukin-17 signaling influences CD8+ T cell immunity and tumor progression according to the IL-17 receptor subunit expression pattern in cancer cellsRodriguez, Constanza / Araujo Furlan, Cintia L. / Tosello Boari, Jimena / Bossio, Sabrina N. / Boccardo, Santiago / Fozzatti, Laura / Canale, Fernando P. / Beccaria, Cristian G. / Nuñez, Nicolás G. / Ceschin, Danilo G. et al. | 2023
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Next-generation CTLA-4 targeting molecules and combination therapy: promising strategies for improving cancer immunotherapyRudqvist, Nils-Petter / Avagyan, Manushak / Chand, Dhan et al. | 2023
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Cellular senescence enhances adaptive anticancer immunosurveillanceMarin, Ines / Serrano, Manuel / Pietrocola, Federico et al. | 2023
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Radiotherapy as a means to increase the efficacy of T-cell therapy in solid tumorsLaurent, Pierre-Antoine / Morel, Daphne / Meziani, Lydia / Depil, Stephane / Deutsch, Eric et al. | 2023
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Mesothelin-targeting T cells bearing a novel T cell receptor fusion construct (TRuC) exhibit potent antitumor efficacy against solid tumorsDing, Jian / Guyette, Sarah / Schrand, Brett / Geirut, Jessica / Horton, Holly / Guo, Guangwu / Delgoffe, Greg / Menk, Ashley / Baeuerle, Patrick A. / Hofmeister, Robert et al. | 2023
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Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibitionCodarri Deak, Laura / Hashimoto, Masao / Umaña, Pablo / Klein, Christian et al. | 2023
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Increased tryptophan, but not increased glucose metabolism, predict resistance of pembrolizumab in stage III/IV melanomaOldan, Jorge D. / Giglio, Benjamin C. / Smith, Eric / Zhao, Weiling / Bouchard, Deeanna M. / Ivanovic, Marija / Lee, Yueh Z. / Collichio, Frances A. / Meyers, Michael O. / Wallack, Diana E. et al. | 2023
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A type I interferon footprint in pre-operative biopsies is an independent biomarker that in combination with CD8+ T cell quantification can improve the prediction of response to neoadjuvant treatment of rectal adenocarcinomaRezapour, Azar / Rydbeck, Daniel / Byvald, Fabian / Tasselius, Viktor / Danielsson, Gustaf / Angenete, Eva / Yrlid, Ulf et al. | 2023
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M2 macrophage-derived exosomes suppress tumor intrinsic immunogenicity to confer immunotherapy resistanceZheng, Naisheng / Wang, Tingting / Luo, Qin / Liu, Yi / Yang, Junyao / Zhou, Yunlan / Xie, Guohua / Ma, Yanhui / Yuan, Xiangliang / Shen, Lisong et al. | 2023
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Prevention and treatment of cancers by tumor antigen-expressing Staphylococcus epidermidisKepp, Oliver / Zitvogel, Laurence / Kroemer, Guido et al. | 2023
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Mammary carcinoma: toward a realistic mouse model of incurable cancersPérez-Lanzón, Maria / Maiuri, Maria Chiara / Lopez-Otin, Carlos / Kroemer, Guido et al. | 2023
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Light on life: immunoscore immune-checkpoint, a predictor of immunotherapy responseHijazi, Assia / Antoniotti, Carlotta / Cremolini, Chiara / Galon, Jérôme et al. | 2023
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Digital spatial profiling of melanoma shows CD95 expression in immune cells is associated with resistance to immunotherapyMartinez-Morilla, Sandra / Moutafi, Myrto / Fernandez, Aileen I. / Jessel, Shlomit / Divakar, Prajan / Wong, Pok Fai / Garcia-Milian, Rolando / Schalper, Kurt A. / Kluger, Harriet M. / Rimm, David L. et al. | 2023
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Immunogenic chemotherapy sensitizes RAS-mutated colorectal cancers to immune checkpoint inhibitorsBezu, Lucillia / Kepp, Oliver / Kroemer, Guido et al. | 2023
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Trial watch: beta-blockers in cancer therapyCarnet Le Provost, Killian / Kepp, Oliver / Kroemer, Guido / Bezu, Lucillia et al. | 2023
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Tissue-resident memory T cells in immune-related adverse events: friend or foe?Reschke, Robin / Gajewski, Thomas F et al. | 2023
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Accumulation of tissue-resident natural killer cells, innate lymphoid cells, and CD8+ T cells towards the center of human lung tumorsBrownlie, Demi / von Kries, Andreas / Valenzano, Giampiero / Wild, Nicole / Yilmaz, Emel / Säfholm, Jesper / Al-Ameri, Mamdoh / Alici, Evren / Ljunggren, Hans-Gustaf / Schliemann, Igor et al. | 2023
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CD39+ conventional CD4+ T cells with exhaustion traits and cytotoxic potential infiltrate tumors and expand upon CTLA-4 blockadeBossio, Sabrina N. / Abrate, Carolina / Tosello Boari, Jimena / Rodriguez, Constanza / Canale, Fernando P. / Ramello, María C. / Brunotto, Valentina / Richer, Wilfrid / Rocha, Dario / Sedlik, Christine et al. | 2023
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Overcoming the resistance of hepatocellular carcinoma to PD-1/PD-L1 inhibitor and the resultant immunosuppression by CD38 siRNA-loaded extracellular vesiclesDeng, Jun / Ke, Hui et al. | 2023
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Tertiary lymphoid structures in desmoplastic melanoma have increased lymphocyte density, lymphocyte proliferation, and immune cross talk with tumor when compared to non-desmoplastic melanomasEdmonds, Nicole L. / Gradecki, Sarah E / Katyal, Priya / Lynch, Kevin T / Stowman, Anne M / Gru, Alejandro A / Engelhard, Victor H / Slingluff, Craig LJr. / Mauldin, Ileana S. et al. | 2023
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Gankyrin-mediated interaction between cancer cells and tumor-associated macrophages facilitates prostate cancer progression and androgen deprivation therapy resistancePeng, Guang / Wang, Chao / Wang, Hongru / Qu, Min / Dong, Keqin / Yu, Yongwei / Jiang, Yuquan / Gan, Sishun / Gao, Xu et al. | 2023
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Expression of OLR1 gene on tumor-associated macrophages of head and neck squamous cell carcinoma, and its correlation with clinical outcomeZhang, Peng / Zhao, Yan / Xia, Xin / Mei, Song / Huang, Yixuan / Zhu, Yingying / Yu, Shuting / Chen, Xingming et al. | 2023
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CARD9 deficiency promotes pancreatic cancer growth by blocking dendritic cell maturation via SLC6A8-mediated creatine transportTian, Cheng / Yuan, Huimin / Lu, Yi / He, Henghui / Li, Qing / Li, Senlin / Yang, Jian / Wang, Mengheng / Xu, Ruochen / Liu, Qian et al. | 2023
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Systemic administration of mesenchymal stem cells loaded with a novel oncolytic adenovirus carrying a bispecific T cell engager against hepatocellular carcinomaYuan, Xiangfei / Lu, Yang / Yang, Yuanyuan / Tian, Wencong / Fan, Dongmei / Liu, Ruoqi / Lei, Xiaomin / Xia, Yafei / Yang, Lei / Yan, Shu et al. | 2023
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Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1Mukherjee, Debayan / Romano, Erminia / Walshaw, Richard / Zeef, Leo A. H. / Banyard, Antonia / Kitcatt, Stephen J. / Cheadle, Eleanor J. / Tuomela, Karoliina / Pendharkar, Swati / Al-Deka, Aws et al. | 2023
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Microbiota-associated immunotherapy resistance caused by deficient PD-L2 - RGMb signalingFidelle, Marine / Lebhar, Isabelle / Zitvogel, Laurence / Kroemer, Guido et al. | 2023
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Formyl peptide receptor-1 (FPR1) represses intestinal oncogenesisLe Naour, Julie / Montégut, Léa / Pan, Yuhong / Scuderi, Sarah Adriana / Cordier, Pierre / Joseph, Adrien / Sauvat, Allan / Iebba, Valerio / Paillet, Juliette / Ferrere, Gladys et al. | 2023
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PD-L1 (CD274) promoter hypomethylation predicts immunotherapy response in metastatic urothelial carcinomaKlümper, Niklas / Wüst, Lennert / Saal, Jonas / Ralser, Damian J. / Zarbl, Romina / Jarczyk, Jonas / Breyer, Johannes / Sikic, Danijel / Wullich, Bernd / Bolenz, Christian et al. | 2023
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g-NK cells from umbilical cord blood are phenotypically and functionally different than g-NK cells from peripheral bloodGao, Fei / Mora, Mauricio Campos / Constantinides, Michael / Coenon, Loïs / Multrier, Caroline / Vaillant, Loïc / Zhang, Tianxiang / Villalba, Martin et al. | 2023
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ADAM12 abrogation alters immune cell infiltration and improves response to checkpoint blockade therapy in the T11 murine model of triple-negative breast cancerWang, Guanpeng / Romero, Yeni / Thevarajan, Indhujah / Zolkiewska, Anna et al. | 2023
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Arsenic trioxide as an inducer of immunogenic cell deathKepp, Oliver / Pan, Hui / Liu, Peng / Kroemer, Guido et al. | 2023
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Ferroptosis: friend or foe in cancer immunotherapy?Demuynck, Robin / Efimova, Iuliia / Catanzaro, Elena / Krysko, Dmitri V et al. | 2023
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Analysis of RBP expression and binding sites identifies PTBP1 as a regulator of CD19 expression in B-ALLZiegler, Nicole / Cortés-López, Mariela / Alt, Francesca / Sprang, Maximilian / Ustjanzew, Arsenij / Lehmann, Nadine / El Malki, Khalifa / Wingerter, Arthur / Russo, Alexandra / Beck, Olaf et al. | 2023
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Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancerCarbonnier, Vincent / Le Naour, Julie / Bachelot, Thomas / Vacchelli, Erika / André, Fabrice / Delaloge, Suzette / Kroemer, Guido et al. | 2023
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Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cellsKajihara, Nabeel / Tanaka, Yoshino / Takeuchi, Riko / Kobayashi, Takuto / Tanji, Masafumi / Ataka, Tsukasa / Nakano, Shiho / Yamada, Taisho / Takaoka, Akinori / Hasegawa, Yoshinori et al. | 2023
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A Chemically Defined TLR3 Agonist with Anticancer ActivityLe Naour, Julie / Thierry, Sylvain / Scuderi, Sarah Adriana / Boucard-Jourdin, Mathilde / Liu, Peng / Bonnin, Marc / Pan, Yuhong / Perret, Clémence / Zhao, Liwei / Mao, Misha et al. | 2023
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CD11c+ and IRF8+ cell densities in rectal cancer biopsies predict outcomes of neoadjuvant chemoradiotherapyTse, Benita C. Y. / Bergamin, Sarah / Steffen, Pascal / Hruby, George / Pavlakis, Nick / Clarke, Stephen J. / Evans, Justin / Engel, Alexander / Kneebone, Andrew / Molloy, Mark P. et al. | 2023
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Enhancing T cell anti-tumor efficacy with a PD1-TIGIT chimeric immune-checkpoint switch receptorZhao, Jingjing / Dong, Jiebin / Deng, Changwen / Zhang, Qianjing / Sun, Shicheng / Li, Honggang / Bai, Yun / Deng, Hongkui et al. | 2023
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Identification and characterization of the anti-viral interferon lambda 3 as direct target of the Epstein-Barr virus microRNA-BART7-3pBlümke, Juliane / Bauer, Marcus / Vaxevanis, Christoforos / Wilfer, Andreas / Mandelboim, Ofer / Wickenhauser, Claudia / Seliger, Barbara / Jasinski-Bergner, Simon et al. | 2023
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Macrophage infiltration promotes regrowth in MYCN-amplified neuroblastoma after chemotherapyValind, Anders / Verhoeven, Bronte Manouk / Enoksson, Jens / Karlsson, Jenny / Christensson, Gustav / Mañas, Adriana / Aaltonen, Kristina / Jansson, Caroline / Bexell, Daniel / Baryawno, Ninib et al. | 2023
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An engineered T-cell engager with selectivity for high mesothelin-expressing cells and activity in the presence of soluble mesothelinSnell, Daniel / Gunde, Tea / Warmuth, Stefan / Chatterjee, Bithi / Brock, Matthias / Hess, Christian / Johansson, Maria / Simonin, Alexandre / Spiga, Fabio Mario / Weinert, Christopher et al. | 2023
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A mechanism of IL-34-induced resistance against cytotoxic anti-cancer therapies such as radiation by X-ray and chemotherapy by OxaliplatinHan, Nanumi / Wada, Haruka / Kobayashi, Takuto / Otsuka, Ryo / Seino, Ken-Ichiro et al. | 2023
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TNBC-derived Gal3BP/Gal3 complex induces immunosuppression through CD45 receptorRaiter, Annat / Lipovetsky, Julia / Stenbac, Asaf / Lubin, Ido / Yerushalmi, Rinat et al. | 2023
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PB101, a VEGF- and PlGF-targeting decoy protein, enhances antitumor immunity and suppresses tumor progression and metastasisGo, Eun-Jin / Yang, Hannah / Lee, Seung Joon / Yang, Hyun Gul / Shin, Jin A. / Lee, Won Suk / Lim, Hye Seong / Chon, Hong Jae / Kim, Chan et al. | 2023
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Piezo1 facilitates optimal T cell activation during tumor challengeabiff, muta / Alshebremi, Mohammad / Bonner, Melissa / Myers, Jay T. / Kim, Byung-Gyu / Tomchuck, Suzanne L. / Santin, Alicia / Kingsley, Daniel / Choi, Sung Hee / Huang, Alex Y. et al. | 2023
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Prognostic and predictive value of Immunoscore and its correlation with ctDNA in stage II colorectal cancerWang, Fulong / Lu, Shixun / Cao, Di / Qian, Juanjuan / Li, Cong / Zhang, Rongxin / Wang, Feng / Wu, Miaoqing / Liu, Yifan / Pan, Zhizhong et al. | 2023
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Daratumumab induces cell-mediated cytotoxicity of primary effusion lymphoma and is active against refractory diseaseShrestha, Prabha / Astter, Yana / Davis, David A. / Zhou, Ting / Yuan, Constance M. / Ramaswami, Ramya / Wang, Hao-Wei / Lurain, Kathryn / Yarchoan, Robert et al. | 2023
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A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor responseRubio-Pérez, Laura / Lázaro-Gorines, Rodrigo / Harwood, Seandean L. / Compte, Marta / Navarro, Rocío / Tapia-Galisteo, Antonio / Bonet, Jaume / Blanco, Belén / Lykkemark, Simon / Ramírez-Fernández, Ángel et al. | 2023
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Novel Fab-peptide-HLA-I fusion proteins for redirecting pre-existing anti-CMV T cell immunity to selectively eliminate carcinoma cellsBritsch, Isabel / van Wijngaarden, Anne P. / Ke, Xiurong / Hendriks, Mark. A.J.M. / Samplonius, Douwe F. / Ploeg, Emily M. / Helfrich, Wijnand et al. | 2023
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Homogeneity in immune features between colorectal liver metastases better identifies patients with good prognosis compared to pathological response to preoperative chemotherapyHenault, David / Stephen, David / St-Hilaire, Pierre-Antoine / Messaoudi, Nouredin / Vandenbroucke-Menu, Franck / Simoneau, Eve / Rong, Zhixia / Plasse, Marylène / Létourneau, Richard / Roy, André et al. | 2023
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Immune checkpoint blockade therapy mitigates systemic inflammation and affects cellular FLIP-expressing monocytic myeloid-derived suppressor cells in non-progressor non-small cell lung cancer patientsAdamo, Annalisa / Frusteri, Cristina / Pilotto, Sara / Caligola, Simone / Belluomini, Lorenzo / Poffe, Ornella / Giacobazzi, Luca / Dusi, Silvia / Musiu, Chiara / Hu, Yushu et al. | 2023
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Cell type-specific induction of ferroptosis to boost antitumor immunityLiu, Jiao / Li, Jingbo / Kang, Rui / Tang, Daolin et al. | 2023