Adverse drug event risk assessment by the virtual addition of COVID‐19 repurposed drugs to Medicare and commercially insured patients’ drug regimens: A drug safety simulation study (English)
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In:
Clinical and Translational Science
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14
, 5
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1799-1809
;
2021
- Article (Journal) / Electronic Resource
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Title:Adverse drug event risk assessment by the virtual addition of COVID‐19 repurposed drugs to Medicare and commercially insured patients’ drug regimens: A drug safety simulation study
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Contributors:Smith, Matt K. ( author ) / Bikmetov, Ravil ( author ) / Al Rihani, Sweilem B. ( author ) / Deodhar, Malavika ( author ) / Hafermann, Matthew ( author ) / Dow, Pamela ( author ) / Turgeon, Jacques ( author ) / Michaud, Veronique ( author )
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Published in:Clinical and Translational Science ; 14, 5 ; 1799-1809
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Publisher:
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Publication date:2021-09-01
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Size:11 pages
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ISSN:
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DOI:
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Type of media:Article (Journal)
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Type of material:Electronic Resource
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Language:English
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Source:
Table of contents – Volume 14, Issue 5
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 1621
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Issue Information| 2021
- 1625
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Autoantibodies in moderate and critical cases of COVID‐19Chang, Soon Hee / Minn, Dohsik / Kim, Yu Kyung et al. | 2021
- 1627
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Antinuclear antibodies in COVID 19Muratori, Paolo / Lenzi, Marco / Muratori, Luigi / Granito, Alessandro et al. | 2021
- 1629
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Opportunities and challenges in translational scienceAustin, Christopher P. et al. | 2021
- 1648
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HLA‐associated adverse drug reactions ‐ scoping reviewJeiziner, Chiara / Wernli, Ursina / Suter, Katja / Hersberger, Kurt E. / Meyer zu Schwabedissen, Henriette E. et al. | 2021
- 1659
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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory considerationWang, Hongbing / Brown, Paul C. / Chow, Edwin C.Y. / Ewart, Lorna / Ferguson, Stephen S. / Fitzpatrick, Suzanne / Freedman, Benjamin S. / Guo, Grace L. / Hedrich, William / Heyward, Scott et al. | 2021
- 1681
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Optimizing clinical phenotyping to better delineate the complex relationship between type 2 diabetes and Alzheimer’s diseaseHanson, Angela J. / Rubinow, Katya B. et al. | 2021
- 1689
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Design and conduct considerations for studies in patients with impaired renal functionRavenstijn, Paulien / Chetty, Manoranjenni / Manchandani, Pooja et al. | 2021
- 1705
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Practical publication metrics for academicsMyers, Bethany A. / Kahn, Katherine L. et al. | 2021
- 1713
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Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraceptionLazorwitz, Aaron / Aquilante, Christina L. / Shortt, Jonathan A. / Sheeder, Jeanelle / Teal, Stephanie / Gignoux, Christopher R. et al. | 2021
- 1719
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Application of MCAT questions as a testing tool and evaluation metric for knowledge graph–based reasoning systemsFecho, Karamarie / Balhoff, James / Bizon, Chris / Byrd, William E. / Hang, Sui / Koslicki, David / Rensi, Stefano E. / Schmitt, Patrick L. / Wawer, Mathias J. / Williams, Mark et al. | 2021
- 1725
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Analysis of GABRG2 C588T polymorphism in genetic epilepsy and evaluation of GABRG2 in drug treatmentWang, Shitao / Zhang, Xianjun / Zhou, Liang / Wu, Qian / Han, Yanbing et al. | 2021
- 1734
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Influence of 4‐week or 12‐week glucocorticoid treatment on metabolic changes in patients with active moderate‐to‐severe thyroid‐associated ophthalmopathyChen, Xiaoman / Abudukerimu, Buatikamu / Li, Qin / Li, Qing / Qiao, Jie / Lin, Dongping / Sui, Chunhua / Ye, Lin / Zhai, Hualing / Jiang, Boren et al. | 2021
- 1747
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Tissue pharmacokinetics of DHP107, a novel lipid‐based oral formulation of paclitaxel, in mice and patients by positron emission tomographyMoon, Byung Seok / Park, Hyun Soo / Sunwoo, Jung / Lee, In‐Hyun / Kim, Anhye / Moon, Seol Ju / Lee, Heechan / Son, Min Hee / Kim, Su Bin / Park, Sun Mi et al. | 2021
- 1756
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Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and pharmacodynamics in a randomized phase I trialKaul, Martin / End, Peter / Cabanski, Maciej / Schuhler, Carole / Jakab, Annamaria / Kistowska, Magdalena / Kinhikar, Arvind / Maiolica, Alessio / Sinn, Angela / Fuhr, Rainard et al. | 2021
- 1769
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Safety, tolerability, pharmacokinetics, and pharmacodynamics of HBM9161, a novel FcRn inhibitor, in a phase I study for healthy Chinese volunteersYap, Desmond Y. H. / Hai, Jojo / Lee, Paul C. H. / Zhou, Xueying / Lee, Michael / Zhang, Yu / Wang, Meng / Chen, Xiaoxiang et al. | 2021
- 1780
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An evaluation on the association of vancomycin trough concentration with mortality in critically ill patients: A multicenter retrospective studyRen, Jiajia / Hou, Yanli / Li, Jiamei / Gao, Ya / Li, Ruohan / Jin, Xuting / Zhang, Jingjing / Wang, Xiaochuang / Wang, Gang et al. | 2021
- 1791
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Immune response profiling in patients with traumatic injuries associated with alcohol ingestionBreslin, Adam W. / Limkakeng, Alexander T. / Silvius, Elizabeth / Staton, Catherine A. / Almond, Chandra / Joshi, Mary‐Beth / Adams, Bartley / Johnston, Bria / McGowan, Lauren / Kirk, Allan D. et al. | 2021
- 1799
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Adverse drug event risk assessment by the virtual addition of COVID‐19 repurposed drugs to Medicare and commercially insured patients’ drug regimens: A drug safety simulation studySmith, Matt K. / Bikmetov, Ravil / Al Rihani, Sweilem B. / Deodhar, Malavika / Hafermann, Matthew / Dow, Pamela / Turgeon, Jacques / Michaud, Veronique et al. | 2021
- 1810
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Dose selection for intracerebroventricular cerliponase alfa in children with CLN2 disease, translation from animal to human in a rare genetic diseaseHammon, Kevin / de Hart, Greg / Vuillemenot, Brian R. / Kennedy, Derek / Musson, Don / O’Neill, Charles A. / Katz, Martin L. / Henshaw, Joshua W. et al. | 2021
- 1822
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SMAD4 loss is associated with response to neoadjuvant chemotherapy plus hydroxychloroquine in patients with pancreatic adenocarcinomaFei, Naomi / Wen, Sijin / Ramanathan, Rajesh / Hogg, Melissa E. / Zureikat, Amer H. / Lotze, Michael T. / Bahary, Nathan / Singhi, Aatur D. / Zeh, Herbert J. / Boone, Brian A. et al. | 2021
- 1830
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Preoperative medication use and development of postoperative delirium and cognitive dysfunctionHeinrich, Maria / Nottbrock, Anja / Borchers, Friedrich / Mörgeli, Rudolf / Kruppa, Jochen / Winterer, Georg / Slooter, Arjen J. C. / Spies, Claudia / the BioCog Consortium et al. | 2021
- 1841
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Patients with geographic barriers to health care access are prescribed a higher proportion of drugs with pharmacogenetic testing guidelinesDalton, Rachel / Brown, Joshua D. / Duarte, Julio D. et al. | 2021
- 1853
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Macrophage migration inhibitory factor predicts an unfavorable outcome after transarterial chemoembolization for hepatic malignanciesWirtz, Theresa H. / Loosen, Sven H. / Schulze‐Hagen, Max / Gorgulho, Joao / Kandler, Jennis / Joerdens, Markus / Demir, Münevver / Mohr, Raphael / Bruners, Philipp / Kuhl, Christiane et al. | 2021
- 1864
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Application of machine learning to predict reduction in total PANSS score and enrich enrollment in schizophrenia clinical trialsPodichetty, Jagdeep T. / Silvola, Rebecca M. / Rodriguez‐Romero, Violeta / Bergstrom, Richard F. / Vakilynejad, Majid / Bies, Robert R. / Stratford, Robert E. Jr. et al. | 2021
- 1875
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Safety and pharmacokinetics of docetaxel in combination with pegvorhyaluronidase alfa in patients with non‐small cell lung cancerHeineman, Thomas / Baumgart, Megan / Nanavati, Charvi / Gabrail, Nash / Van Wart, Scott A. / Mager, Donald E. / Maneval, Daniel C. / Fathallah, Anas M. / Sekulovich, Rose E. et al. | 2021
- 1886
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Effect of difelikefalin, a selective kappa opioid receptor agonist, on respiratory depression: A randomized, double‐blind, placebo‐controlled trialViscusi, Eugene R. / Torjman, Marc C. / Munera, Catherine L. / Stauffer, Joseph W. / Setnik, Beatrice S. / Bagal, Sukirti N. et al. | 2021
- 1894
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Pharmacokinetic, pharmacodynamic, and immunogenic rationale for optimal dosing of pegvaliase, a PEGylated bacterial enzyme, in adult patients with phenylketonuriaQi, Yulan / Patel, Gina / Henshaw, Joshua / Gupta, Soumi / Olbertz, Joy / Larimore, Kevin / Harding, Cary O. / Merilainen, Markus / Zori, Roberto / Longo, Nicola et al. | 2021
- 1906
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Effects of 5‐HT₃ receptor antagonists on cisplatin‐induced kidney injuryGoda, Mitsuhiro / Kanda, Masaya / Yoshioka, Toshihiko / Yoshida, Ami / Murai, Yoichi / Zamami, Yoshito / Aizawa, Fuka / Niimura, Takahiro / Hamano, Hirofumi / Okada, Naoto et al. | 2021
- 1917
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The timing of 30‐month stay expirations and generic entry: A cohort study of first generics, 2013–2020Kannappan, Sunand / Darrow, Jonathan J. / Kesselheim, Aaron S. / Beall, Reed F. et al. | 2021
- 1924
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Application of a PBPK model to elucidate the changes of systemic and liver exposures for rosuvastatin, carotegrast, and bromfenac followed by OATP inhibition in monkeysCheng, Yaofeng / Liang, Xiaomin / Hao, Jia / Niu, Congrong / Lai, Yurong et al. | 2021
- 1935
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Safety, tolerability, and pharmacokinetics of single‐ and multiple‐dose administration of islatravir (MK‐8591) in adults without HIVMatthews, Randolph P. / Ankrom, Wendy / Friedman, Evan / Jackson Rudd, Deanne / Liu, Yang / Mogg, Robin / Panebianco, Deborah / De Lepeleire, Inge / Petkova, Magdalena / Grobler, Jay A. et al. | 2021
- 1945
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Translational and pharmacokinetic‐pharmacodynamic application for the clinical development of GDC‐0334, a novel TRPA1 inhibitorChan, Phyllis / Ding, Han Ting / Liederer, Bianca M. / Mao, Jialin / Belloni, Paula / Chen, Liuxi / Gao, Simon S. / Joseph, Victory / Yang, Xiaoying / Lin, Joseph S. et al. | 2021
- 1955
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Effects of vancomycin‐induced gut microbiome alteration on the pharmacodynamics of metformin in healthy male subjectsKim, Eunwoo / Kim, Andrew Hyoungjin / Lee, Yujin / Ji, Sang Chun / Cho, Joo‐Youn / Yu, Kyung‐Sang / Chung, Jae‐Yong et al. | 2021
- 1967
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A phase I study of high dose camostat mesylate in healthy adults provides a rationale to repurpose the TMPRSS2 inhibitor for the treatment of COVID‐19Kitagawa, Junsaku / Arai, Hayato / Iida, Hiroyuki / Mukai, Jiro / Furukawa, Kenji / Ohtsu, Seitaro / Nakade, Susumu / Hikima, Tomohiro / Haranaka, Miwa / Uemura, Naoto et al. | 2021
- 1977
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Particle size affects pharmacokinetics of milled oxycodone hydrochloride tablet products following nasal insufflation in nondependent, recreational opioid usersRaofi, Saeid / Kinjo, Minori / Sun, Dajun / Li, Zhichuan / Boyce, Heather / Natarajan, Karthika / Frost, Mitchell / Zhao, Liang / Luke, Markham / Lionberger, Robert et al. | 2021
- 1988
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Modeling and simulation to predict the degree of disability over time in acute ischemic stroke patientsPark, Sang‐In / Kang, Dong‐Wha / Lim, Hyeong‐Seok et al. | 2021
- 1997
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Tilidine and dipyrone (metamizole) in cold pressor pain: A pooled analysis of efficacy, tolerability, and safety in healthy volunteersKleine‐Borgmann, Julian / Wilhelmi, Johannes / Kratel, Johannes / Baumann, Frederik / Schmidt, Katharina / Zunhammer, Matthias / Bingel, Ulrike et al. | 2021
- 2008
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Are body surface area based estimates of liver volume applicable to children with overweight or obesity? An in vivo validation studyHosey‐Cojocari, Chelsea / Chan, Sherwin S. / Friesen, Chance S. / Robinson, Amie / Williams, Veronica / Swanson, Erica / O’Toole, Daniel / Radford, Jansynn / Mardis, Neil / Johnson, Trevor N. et al. | 2021
- 2017
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Safety, tolerability, and pharmacokinetics of oral baicalein tablets in healthy Chinese subjects: A single‐center, randomized, double‐blind, placebo‐controlled multiple‐ascending‐dose studyLi, Lijun / Gao, Hongzhi / Lou, Kun / Luo, Hongmei / Hao, Sheng / Yuan, Jing / Liu, Zeyuan / Dong, Ruihua et al. | 2021
- 2025
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Metabolomic profiling of extraesophageal reflux disease in childrenMahoney, Lisa B. / Esther, Charles R. Jr / May, Kara / Rosen, Rachel et al. | 2021
- 2034
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Association of CYP3A5 polymorphisms and parathyroid hormone with blood level of tacrolimus in patients with end‐stage renal diseaseTanaka, Ryota / Suzuki, Yosuke / Watanabe, Hiroshi / Fujioka, Takashi / Hirata, Kenshiro / Shin, Toshitaka / Ando, Tadasuke / Ono, Hiroyuki / Tatsuta, Ryosuke / Mimata, Hiromitsu et al. | 2021
- 2043
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Persistent follicular granulosa cell senescence and apoptosis induced by methotrexate leading to oocyte dysfunction and aberrant embryo developmentFu, Jingbo / Liu, Yang / Wang, Chen / Zhang, Hongxia / Yu, Bin / Wang, Ye / Zhu, Haiying et al. | 2021
- 2075
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Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK PathwayHe, Hongtao / Qiao, Kuangyuan / Wang, Chao / Yang, Wuhan / Xu, Zhuo / Zhang, Zhilei / Jia, Yuming / Zhang, Chong / Peng, Li et al. | 2021
- 2085
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Expression of Concern: Zhou, Y., & Zhou, J. Tranilast Treatment Attenuates Cerebral Ischemia‐Reperfusion Injury in Rats Through the Inhibition of Inflammatory Responses Mediated by NF‐κB and PPARs, Clin. Trans. Sci. https://ascpt.onlinelibrary.wiley.com/doi/10.1111/cts.12606| 2021
- 2086
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Expression of Concern: He, H., Qiao, K., Wang, C., Yang, W., Xu, Z., Zhang, Z., Jia, Y., Zhang, C., & Peng L. Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK Pathway, Clin. Trans. Sci. https://ascpt.onlinelibrary.wiley.com/doi/full/10.1111/cts.12765| 2021