Distribution (English)
- New search for: Riviere, Jim E.
- New search for: Buur, Jennifer
- New search for: Riviere, Jim E.
- New search for: Buur, Jennifer
In:
Comparative Pharmacokinetics
: Principles, Techniques, and Applications
;
73-90
;
2011
-
ISBN:
- Article/Chapter (Book) / Electronic Resource
-
Title:Distribution
-
Contributors:Riviere, Jim E. ( author ) / Buur, Jennifer ( author )
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Published in:Comparative Pharmacokinetics : Principles, Techniques, and Applications ; 73-90
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Publisher:
- New search for: Wiley‐Blackwell
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Place of publication:Oxford, UK
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Publication date:2011-03-25
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Size:18 pages
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ISBN:
-
DOI:
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Type of media:Article/Chapter (Book)
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Type of material:Electronic Resource
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Language:English
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Keywords:xenobiotic, absorbed into systemic circulation , P‐glycoprotein, one of the best understood efflux transporters , organs, anatomical barriers to xenobiotic penetration ‐ the blood‐brain barrier , chemical distribution in peripheral tissues ‐ and four factors , plasma protein binding , AUC, metric representing blood‐tissue partitioning ‐ indicator of systemic exposure , toxic effects, or enhanced activity ‐ higher concentration of free xenobiotic , distribution , stereoselectivity in drug disposition ‐ often‐ignored phenomenon influencing studies , body fluids, three primary compartments ‐ one, being vascular fluid
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Source:
Table of contents eBook
The tables of contents are generated automatically and are based on the data records of the individual contributions available in the index of the TIB portal. The display of the Tables of Contents may therefore be incomplete.
- 3
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IntroductionRiviere, Jim E. et al. | 2011
- 13
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Principles of Drug Movement in the BodyRiviere, Jim E. et al. | 2011
- 27
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Quantitative Structure–Permeability RelationshipsRiviere, Jim E. / Xia, Xin‐Rui et al. | 2011
- 39
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AbsorptionRiviere, Jim E. et al. | 2011
- 73
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DistributionRiviere, Jim E. / Buur, Jennifer et al. | 2011
- 91
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Renal EliminationRiviere, Jim E. et al. | 2011
- 113
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Hepatic Biotransformation and Biliary ExcretionRiviere, Jim E. / Baynes, Ronald et al. | 2011
- 143
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Compartmental ModelsRiviere, Jim E. et al. | 2011
- 187
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Noncompartmental ModelsRiviere, Jim E. et al. | 2011
- 207
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Nonlinear ModelsRiviere, Jim E. et al. | 2011
- 225
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Physiological ModelsRiviere, Jim E. / Leavens, Teresa et al. | 2011
- 241
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Dosage RegimensRiviere, Jim E. et al. | 2011
- 255
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Simultaneous Pharmacokinetic–Pharmacodynamic ModelingRiviere, Jim E. / Toutain, Pierre‐Louis et al. | 2011
- 295
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Study Design and Data AnalysisRiviere, Jim E. / Chittenden, Jason et al. | 2011
- 315
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Bioequivalence StudiesRiviere, Jim E. / Martinez, Marilyn et al. | 2011
- 347
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Population Pharmacokinetic ModelsRiviere, Jim E. / Chittenden, Jason et al. | 2011
- 379
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Dosage Adjustments in Disease StatesRiviere, Jim E. / Davis, Jennifer et al. | 2011
- 399
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Interspecies ExtrapolationsRiviere, Jim E. et al. | 2011
- 413
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Tissue Residues and Withdrawal TimesRiviere, Jim E. et al. | 2011
- 425
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IndexRiviere, Jim E. et al. | 2011
- i
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Front MatterRiviere, Jim E. et al. | 2011